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1. Official method of determining particle size?

MODULAR EXAM A. Sieve analysis

B. Sedimentation method

RATIONALE C. Coulter counter

D. Optical microscopy
Module5

CORRECT ANSWER: A

2. Point where solid A & B and liquid phase co- 3-6. Choose from the ff. choices below
A. Drug trader
exist. B. Drug distributor/Importer
A. Critical point C. Drug manufacturer
D. Drug distributor/Wholesaler
B. Eutectic point
C. Triple point 3. Any establishment engaged in operations involved in the
production of a drug.
D. Tie point 4. Any establishment which is a registered owner of the
drug product but subcontracts a licensed manufacturer.
5. Any establishment that imports raw materials, active
ingredients or finished products.
6. Any establishments that exports raw materials, active
ingredients or finished products from local establishments
for local distribution on wholesale basis.
CORRECT ANSWER: B

7. A type of filter media except: Match the ff:

A. BHT
A. Polyamide B. Glycerin
B. Nylon C. Bentonite
D. Thimerosal
C. Veegum
D. Cellulose nitrate 8. Humectant
9. Viscosity enhancer
10. Antioxidant
11. Preservative

CORRECT ANSWER: C

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12. Arrange properly the sequences in manufacturing of

emulsion. 13. Preservativ e commonly used for prev ention of
I. Adjusting the final weight when it reduces to 35°C mold growth?
II. Aqueous phase is heated to the same temperature
III. Two phases are mixed A. Methyl paraben
IV. Oil phase is heated at about 5-10°C above the melting B. Propyl paraben
point of the ingredient with the highest melting point
V. Volatile ingredients are added at the lowest C. Sorbic acid
temperature as possible as 45-55°C. D. BHT
[Link], III, IV, V, I
[Link], II, III, V, I
[Link], II, IV, V, I
[Link],III, II, V, I
CORRECT ANSWER: B CORRECT ANSWER: A

14-17. Choose from the ff: 18. HEPA filter is used to achieve a class 100
A. Compounding area condition. It is 99.97% efficient in removing
B. Aseptic filling area 0.3µm particles from air.
C. Material support area
D. Quarantine area A. S1 is true, S2 is false
14. What production area in parenteral manufacturing B. S1&S2 are both false
establishment is constructed of impervious C. S1 is false, S2 is true
material? D. S1&S2 are both true
15. What production area where most stringent control
is practiced?
16. What is the heart of production area?
17. Part of production that serves as storage while
waiting for Q.C. results.
CORRECT ANSWER: D

19. It refers to pharmaceutical research and 20. In the compounding of Calamine lotion, what
manufacturing companies providing pharmacists is the use of liquid phenol?
with medicines in pre-fabricates/ ready to take
form A. Disinfectant & antipruritic
B. Astringent & protective
A. Manufacturing pharmacy
B. Industrial pharmacy C. Protectant
D. Preservative
C. Manufacturing firm
D. Hospital pharmacy

CORRECT ANSWER: B CORRECT ANSWER: A

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21. Which of the ff. is not an indication of 22. Type of glass that is not used for parenterals
resorcinol cream?
A. Type I
A. Antifungal
B. Type II
B. Antibacterial
C. Type III
C. Local irritant
D. Type IV
D. Humectant

CORRECT ANSWER: D CORRECT ANSWER: D

23. A plastic material that cannot be autoclave

Types of Glasses
Type Other name Suitability for
Parenterals
Tests
A. Polyethylene
I Highly-resistant Borosilicate Usually for parenterals, Powdered Glass B. Polypropylene
Glass and alkaline prep. (if (PG) and Surface
demonstrated suitable) Glass (SG)Test C. Polyethylene terapthalate
II Treated Soda-lime Glass For acidic , neutral, and Water attack at 121
alkaline parenterals (if C or SG test D. PVC
demonstrated suitable)
III Soda-lime Glass Not for parenterals PG and SG test
unless demonstrated
suitable
IV Non-parenteral/General Not suitable for None
Purpose Glass parenterals

CORRECT ANSWER: A

Polymer of Plastic 24. Section of warehouse division where raw

materials used in production are weighed and
• Polyethylene (PE) measured?
• HDPE [2] - hard thermosets; for solid dosage forms
• LDPE [4] - flexible, durable; for sprays, medicine droppers, parenteral
• Polypropylene (PP) [5]
A. Dispensing area
• high temp resistance B. In-process area (IPQC)
• for autoclavable plastics
C. Returned goods
• Polyethylene Terephthalate (PET) [1]
• for beverages such as mineral water bottles D. Finished products (FPQC
• Polyvinyl Chloride (PVC) [3]
• least resistant to permeation
• for plastics used in blister packs

CORRECT ANSWER: A

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25. Who is in charge in the preparation of QA vs QC

manufacturing order?
Quality Assurance Quality Control
A. Quality control head • Assures that policies are • Tests compliance of raw
followed materials and packaging
B. Production control head • Cooperates with materials
C. Warehouse head regulatory agencies • Performs in-process
• Prepares SOPs quality control
D. Quality assurance head • Audit and monitoring • Monitors environmental
procedures

CORRECT ANSWER: B

26. In pharmaceutical plant design & 27. Also known as 1:10 dilution
construction, penicillins & cephalosporins, shall
be manufactured in the same building to avoid
A. Levigation
contaminations. Anteroom should operate at a
negative pressure relative to the processing B. Blending
area. C. Trituration
D. Geometric dilution
A. S1 is true, S2 is false
B. S1&S2 are both false
C. S1 is false, S2 is true
D. S1&S2 are both true
CORRECT ANSWER: B CORRECT ANSWER: C

28. This is the most pha rmaceutical e legant

paper?
Types of Papers
• Bond Paper - no moisture resistance
A. Waxed paper • Glassine - glazed, transparent paper; moisture-resistant; does
not protect the powder from photodegradation
B. Parchment paper
• Vegetable Parchment - thin, semi-opaque paper; moisture
C. Bond paper resistant
D. Glassine • Waxed Paper - suitable for hygroscopic and deliquescent
powder due to its water-proof property
• Efflorescent – gives off water of crystallization
• Deliquescent – absorbs moisture then liquefies
• Hygroscopic – absorbs moisture but does not liquefy

CORRECT ANSWER: C

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29. This is hydrated aluminium silicate? 30. In emulsion, it happens when there is already
total separation of phases
A. Bentonite
B. Kaolin A. Cracking
C. Tragacanth B. Creaming
D. Veegum C. Phase inversion
D. Coalescence

CORRECT ANSWER: B CORRECT ANSWER: A

31. Which is not a process for water purification? 32. In microencapsulation, this is the most
common wall material
[Link]-exchange A. Lactose
[Link] B. Gelatin
[Link] osmosis C. Silica
[Link] D. Cellulose

CORRECT ANSWER: D CORRECT ANSWER: B

33. Average weight of adult rectal suppositories 34. Which of the ff. substances cannot be
compressed directly?
A.2g
A. ASA
B.4g
B. HCl
C.1g
C. KCl
D.5g
D. NaCl

CORRECT ANSWER: A CORRECT ANSWER: A

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[Link] limit for content uniformity? 36. Convert 250ml to minims

A.80-110% A. 4180 minims

B.85-115% B. 4080 minims
C.85-110% C. 4018 minims
D.85-100% D. 41800 minims

CORRECT ANSWER: B CORRECT ANSWER: B

37. Glycerogelatin component except: 38. Which of the following is not an ophthalmic
ointment?
A. Medicinal substance
[Link] PO4
B. Glycerin
[Link]
C. Water
C. Tobrex
D. Cellulose
[Link]

CORRECT ANSWER: D CORRECT ANSWER: B and D

39. The ff. are tablet hardness tester except: Tester Description
A. Monsanto Stokes- Barrel with a compressible spring
Monsanto held between two plungers
B. Strong-cobb Strong-Cobb Plunger activated by a lever arm,
C. Roche fibrillation which forces an anvil by hydraulic
D. Shimadzu pressure “airpump”
Pfizer Operates like pliers
Erweka A suspended motor driven weight
uniformly transmits pressure
Schleuniger Motor driven anvil crushes tablet in
horizontal position; most widely
used
CORRECT ANSWER: C and D

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40. Generics act of 1988 41. All are regulated drugs except:

A. RA 8203 A. Morphine
B. RA 6675 B. Amobarbital
C. RA 6425 C. Amphetamine
D. RA 9165 D. Methaqualone

CORRECT ANSWER: B CORRECT ANSWER: A

• “Prohibited Drugs” refer to opium and its derivatives such as heroin

42. Comprehensive DDA of EO 173
and morphine; cocoa leaf and its derivatives, principally cocaine,
alpha and beta eucaine; hallucinogenic drugs, such as mescaline, A. RA 8203
lysergic acid diethylamide (LSD) and other substances producing
similar effects; Indian hemp and its derivatives; all preparations made B. RA 6675
from any of the foregoing and other drugs, whether natural or
synthetic, with the physiological effects of a narcotic drug. C. RA 6425
• “Regulated Drugs” refers to sleep-inducing sedatives, such as D. RA 9165
secobarbital, Phenobarbital, barbital, amobarbital and other drugs
which contain a salt or derivative of a salt of barbituric acid; any salt,
isomer or salt of an isomer of amphetamine, such as Benzedrine or
Dexedrine, or any drug which produces a pharmacologic action similar
to amphetamine; and hypnotic drugs such as methaqualone, or any
other compound producing similar pharmacologic effects

CORRECT ANSWER: D

43. License for wholesaler of dangerous drug 44. Initial LTO issued is valid for how many years?

A. S1 A. 1 year
B. S2 B. 2 years
C. S3 C. 3 years
D. S4 D. Lifetime

CORRECT ANSWER: D CORRECT ANSWER: A

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45. Consumer’s act of the Philippines 46. Which of the ff. is not available in the market?
A. RA 7581 [Link]
B. RA 7394 [Link]
C. RA 9711 [Link]
D. RA 8203 [Link]

CORRECT ANSWER: B CORRECT ANSWER: A and D

47-50. Choose from the ff. choices below: 51. It is tamper resistant by design
A. Light resistant
B. Hermetic A. Tape seal
C. Tight
B. Aerosol container
D. Closed container
C. Shrink seal
47. Protects the contents from extraneous solid and from loss D. Bottle seal
of the article under handing, storage and distribution
48. Protects the contents from contaminations by extraneous
liquids.
49. Protects the contents from photochemical deterioration.
50. It is impervious to air or any other gas under the ordinary
condition of handling, shipment or distribution. It is often
sterile.
CORRECT ANSWER: B

52. Condition for a cool place

Storage Condition
A. 2-8°C • Cold - temperature not greater than 8°C
B. 8-15°C • Freezer - -20 to -10°C
• Refrigerator - 2-8°C
C. Not exceeding 80°C
• Cool - 8-15°C
D. -24°C- 10°C • Room Temp - temp prevailing in the work
area
• Controlled Room Temp - 20-25°C
• Warm - 30-40°C
• Excessive Heat - >40°C
CORRECT ANSWER: B

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53. Leaching happens when there is a movement 54. Used to dispense semi-solid dosage forms
of component of container into the contents. such as creams and ointments
Sorption is when the contents adhere to the
containers molecule. A. Collapsible tubes
B. Dropper bottles
A. S1 is true, S2 is false
B. S1&S2 are both false C. Slide box
C. S1 is false, S2 is true D. Application bottles
D. S1&S2 are both true

CORRECT ANSWER: D CORRECT ANSWER: A

55. Beeswax is used in drug cosmetics due to its 56. The cap ability of absorbing skin secret ions like
perspirations
ability to impart good consistency in the product.
What is its melting point? A. Bloom
B. Absorbancy
A. 70-72% C. Adhesiveness
B. 64-68% [Link]
C. 68-70%
D. 62-65%

CORRECT ANSWER: D CORRECT ANSWER: B

58. Which of the ff. is/are not true about CGMP

57. The ff. animal secretions are used in perfume I. Regulations developed by USP
industry except: II. Describe in the code of Federal regulations title
21, Sections 210&211
A. Musk III. It ensures that the finished product has the
correct identity, strength & purity.
B. Ambergris
IV. It is fixed as it is
C. Gum styrax
A.I & IV
D. Civet
[Link] & IV
[Link] & III
[Link] & IV
CORRECT ANSWER: C CORRECT ANSWER: A

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59. Which is not a QC test for troches 60. The ff. are flavorants used in antibiotics
except:
A. Weight
B. Specific gravity A. Anise
C. Pyrogenecity B. Raspberry
D. Melting test C. Cherry
D. Maple

CORRECT ANSWER: C CORRECT ANSWER: A

61. Which of the ff is/are not correctly paired? 62- 65. Choose from the following:
I. Veegum : 6% A. Cold cream
II. Acacia : 10% B. Acid mantle cream
III. Bentonite : 1-3% (5%) C. PEG ointment
IV. Tragacanth : 6% (1-3%)
D. Lanolin USP
A. I & IV
B. III & IV 62. Emulsion base (O/W)
63. Water soluble
C. II & III 64. Hydrous emulsion base (W/O)
D. II & IV 65. Absorption base
CORRECT ANSWER: B

66. If you want to mask the bitter taste of your

Ointment Bases drug. Which one below should you use?
Oleaginous/ Absorption Water- Water-Soluble
Hydrocarbon Removable A. Butterscotch
Petrolatum, USP Hydrophilic Hydrophilic PEG B. Chocolate mint
Petrolatum Ointment
White Petrolatum, USP Lanolin
C. Vanilla
D. Citrus
Yellow Wax
White Wax
Yellow Ointment
White Ointment

CORRECT ANSWER: B

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67. Capsule size that can carry 195-520mg of the 68. Ultra short acting barbiturates except:
preparation?
A. Amobarbital
A. no. 5 B. Methohexital
B. no. 3 C. Thiopental
C. no. 2 D. Pentotal
D. no. 1

CORRECT ANSWER: C CORRECT ANSWER: A

69. Multiplication factor of milli?

Classification Examples
Thiopental, A. 1x10'(
Ultra Short Acting Thiamylal, B. 1x10')
Methohexital
C. 1x10 '+
Pentobarbital,
Short Acting Secobarbital, D. 1x10 ',
Hexobarbital
Amobarbital,
Intermediate Acting
Butabarbital
Long Acting Phenobarbital

CORRECT ANSWER: D

70. Defined as mass/unit volume at fixed

temperature & pressure and expressed in g/cc or
g/cm3
A. Mass
B. Density
C. Specific gravity
D. Weight

CORRECT ANSWER: B

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71. Which is not a unit for pressure

A. atm
B. mmHg
C. BTU
D. psi

CORRECT ANSWER: C

72. Intermolecular force of attraction involving 2

non-polar substances and is aka as London force Intermolecular Forces of Attraction
• Induced Dipole-Induced Dipole
A. dipole-dipole
B. induced dipole- induced dipole
• London Dispersion Forces
C. dipole-induced dipole • Dipole-Induced Dipole Forces
D. ion-dipole • Debye Forces
• Dipole- Dipole Forces
• Keesom Forces
• Hydrogen Bonding
• H- N,O,F
CORRECT ANSWER: B

73. Which of the ff. pertains to intramolecular force 74. If a gas is held at constant temperature , the
I. H bond is a type of intramolecular force
II. They are forces of attraction existing between bonds volume is inversely proportional to the pressure.
within a molecule Compressing a gas to half of its initial volume
III. Bond involved in salt/NaCl is a type of intramolecular doubles its pressure. What is this gas law
force
IV. Bond involve in glucose is also a type of intramolecular
force. A. Boyle’s Law
B. Gay-Lussacs Law
A.I, II & IV
[Link], III & IV
C. Charle’s Law
C.I, III & IV D. Avogadro’s Law
D.d. I,II & III

CORRECT ANSWER: B CORRECT ANSWER: A

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75. Property of metal that enables them to

Gas Laws return to the ir original shape when the force
that causes the change of shape is removed.

A. Malleability
B. Hardness
C. Brittleness
D. Ductility

CORRECT ANSWER: A

76. A solution that contains more solute than it 77. Gram equivalent weights of solute in 1Lite r of
can ordinary dissolve at room temperature
solution
A. Supersaturated
B. Unsaturated A. Molarity
C. Saturated B. Molality
D. concentrated C. Normality
D. Mole fraction

CORRECT ANSWER: A CORRECT ANSWER: C

78. In the laboratory you are asked to compute 79. The ff are correctly paired except:
for the normality of NaOH solution if 20ml A. Osmosis: movement through a semi
portion of 0.2N HCl required exactly 20ml of permeable membrane
NaOH to reach chemical equivalent point.
B. Surface tension: force required to break the
A.0.30N surface film
B.0.10N C. Diffusion:higher to lower concentration
C.0.20N [Link] tension : attractive force to
D.0.05N between miscible liquids

CORRECT ANSWER: C CORRECT ANSWER: D

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81. Which of the ff. is/are not a property of colloid?

80. Amount of heat required to evaporate a liquid I. Exhibits Brownian movement
II. Pass through filter membrane
A. Enthalpy III. Particle size ranges from 1µm to 100µm
B. Vaporization IV. Since i t is composed of aggregates of many
molecules, movement is very slow.
C. Heat of vaporization
A. I & II
D. Latent heat of vaporization
B. III only
C. II only
D. d. II & IV

CORRECT ANSWER: C CORRECT ANSWER: C

82. Colligative properties of a sol ution de pe nds on t he

relative proportion of t he mole cules of the sol ute and
Properties of Colloid the s olvent. W hich of the ff. is/ are not colligative
• Brownian Movement property
• Zigzag movement of colloidal particles I. Elevation of vapour pressure
II. Lowering of boiling point
• Tyndall Effect III. Depression of freezing point
• Beam of light passes through the colloid IV. Osmotic pressure
• Electrically Charged A.I & IV
• Used for gel electrophoresis (SDS-PAGE) B. II & III
• Adsorption C. II & IV
D.I & II
CORRECT ANSWER: D

83. Boric acids phenobarbital & cocaine are all 84. Compute for the osmotic pressure (atm) of a
example of weak electrolytes. What is its Liso 0.995M sucrose solution at 18°c
value?
A. 23.76 atm
A. 3.4 B. 24.02 atm
B. 1.9 C. 22.84 atm
C. 2.0 D. 21.97 atm
D. 4.3

CORRECT ANSWER: C CORRECT ANSWER: A

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85. Compute for the specific gravity of unknown oil, 86. Also known as specific gravity bottle
if it weighs 36.24g and was measured as 44.50ml
A. 0.88 A. Hydrometer
B. 0.86
B. Plummet & sinker
C. 0.84
C. Pycnometer
D. 0.81
D. Leach pycnometer

CORRECT ANSWER: D CORRECT ANSWER: C

87. In relation to the computed specific gravity of 88- 91. Choose from the following:
unknown oil above. This implies that the oil is A. HLB value of 15-20
B. HLB value of 13-16
A. Equal in weight with water
B. Lighter than water C. HLB value of 7-9
D. HLB value of 1-3
C. Heavier than water
D. None of the above
88. Antifoaming agent
89. Solubilizing agents
90. Wetting agents
91. Detergents
CORRECT ANSWER: B

92. Below are all examples of constitutive 93. Benzalkoium chloride is an

property except:
A. non-ionic surfactant
A. Reflection of light B. anionic surfactant
B. Surface characteristics C. ionic surfactant
C. Molecular weight D. cationic
D. Electric property

CORRECT ANSWER: C CORRECT ANSWER: D

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94. It measures the % change in volume of

Types of Surfactant powders after tapping
• Anionic
• Soaps, SLS, SLES A. Carr’s compressibility index
• Cationic B. Hausner’s ratio
• benzalkonium Cl, cetyl pyridinium Cl (Cidex®)
C. Angle of response
• Non-ionic
• cetyl alcohol, cocamide DEA
D. Total volume
• Amphoteric
• ex: betained

CORRECT ANSWER: A

Formula: Formula:

95. You are assigned to make an isotonic solution 96. When you titrate a weak acid and a weak
of 0.6g of atropine SO4 (E=0.13). Using White base. What indicator should you use?
Vincent method compute for the volume you
weighed to make it isotonic A. methyl orange
B. methyl red = WB + SA
A.8.63ml
C. no indicator
B.8.67ml
D. Phenolphthalein = WA + SB
C.8.57ml
D.8.69ml

CORRECT ANSWER: B CORRECT ANSWER: C

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97. If 1gram of solutes dissolves in 30-100 parts 98. An example of channel lattice
of solvent, it is said to be
A. Starch-iodine
A. Soluble B. Cholesteryl benzoate
B. Sparingly soluble C. Boric acid
C. Freely soluble D. Iodoform
D. Slightly soluble

CORRECT ANSWER: B CORRECT ANSWER: A

99. The following are all example of 100. Below are all correctly paired except:
Newtonian flow except:
A. Plastic flow: Bingham bodies
A. acetone B. Pseudoplastic: Shear thinning
B. glycerin C. Thixotropy: Sol-gel transformation
C. water D. Newtonian: water
D. paint

CORRECT ANSWER: D CORRECT ANSWER: C

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