Biomedical Instruments-BME460
Chapter 7: Cardiac Defibrillators
R. S. Khandpur, 2nd Edition, Chapter 26
Dr. Qasem Qananwah
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 1
CHAPTER 7: Cardiac Defibrillator
CHAPTER OUTLINE
• Need for Defibrillator –arrhythmias
• Defibrillation Process
• Defibrillation strength and Duration
• Types of Defibrillators
External
Internal - Endocardial
Internal - Epicardial
• Defibrillation Electrodes
• Implantable Defibrillators
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 2
CHAPTER 7: Cardiac Defibrillator
Introduction
(a)
(b)
Figure : Pacemaker (a) Implantable Defibrillators, (b) External Defibrillator
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 3
CHAPTER 7: Cardiac Defibrillator
Need for Defibrillation
heart muscle fibres are
continuously stimulated by
adjacent cells
Source: [Link]
Figure : Restoration of normal rhythm in fibrillating heart as achieved by direct current shock (arrow) across the chest wall.
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 4
CHAPTER 7: Cardiac Defibrillator
Need for Defibrillation
[Link] [Link]
emergency-nursing/code-blue-defibrillation/
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 5
CHAPTER 7: Cardiac Defibrillator
Need for Defibrillation
• Used to treat ventricular fibrillation (cardiac arrest) loss of coordinated
contraction of muscle fibers in ventricles, death occurs in minutes if left
untreated.
• 500,000 cardiac arrest cases occur annually in US.
• 1,844 out of 12,223 death due to Ischemic heart disease in Jordan
(statistics 2004)
• Defibrillation involves the application of a strong electrical shock designed
to depolarize most of the heart cells simultaneously, which often
reestablishes coordinated contractions and a normal sinus rhythm.
• Exact physical mechanism leading to ventricular fibrillation is not known.
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 6
CHAPTER 7: Cardiac Defibrillator
Defibrillation Curve
Defibrillation Strength Duration Curve
• pulse amplitude in tens of amperes (few thousand volts).
• operator selects energy delivered: 50-400 joules, depends
on:
1. intrinsic characteristics of patient
2. patient’s disease
3. duration of arrhythmia
4. patient’s age
5. type of arrhythmia (more energy required for v. fib.)
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 7
CHAPTER 7: Cardiac Defibrillator
Defibrillation Process
Monophasic and biphasic waveform
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 8
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
• For each minute elapsing between onset of ventricular fibrillation
and first defibrillation, survival decreases by 10%.
• Defibrillators should be portable, battery operated, small size.
• Energy in defibrillators usually stored in large capacitors.
• Total energy stored in capacitor:
1
WC CVC2
2
Vc = capacitor voltage
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 9
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Fig. 26.2: Schematic diagram of a defibrillator
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 10
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Capacitive Discharge Defibrillator
L Rlead
power
supply + Rchest
Vc C
_
Vchest C: (10 – 50)μF, takes about 10s to full charge
2kV Vc: (4,000 - 9,000) V for a maximal Energy of 400J
up to 40% of energy in C can be dissipated in L and Ri
response is slightly underdamped (depends on chest resistance R)
~10 ms t
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 11
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Example: Rlead
power +
supply +
Vchest Rchest
Vc C
_
_
Rchest = 95Ω, Rlead = 5Ω, total energy stored in C is W = 300 J, want
to deliver 90% of W to heart in 8 ms. What value of C should be used?
RL Rlead Rchest
VC t VC 0e t / RL C , t 0
VC(0) = initial capacitor voltage after charging
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 12
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Example (Cont.):
Rchest
Vchest t VC t
Rchest Rlead
Rchest
VC 0e t / RL C
VC 0e t / RL C ……..(1)
Rchest Rlead
Energy stored in capacitor at t = 0:
0 0
W VC iC dt VC C
dVC
dt
dt
0
1
C VC dVC CVC 0 2
….…..(2)
2
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 13
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Example (Cont.):
energy delivered to Rchest:
Wchest t
tV2
chest t dt
0 Rchest
substituting (1):
Wchest t 2
tV2
C
0 e 2t / R LC
dt
0 Rchest
using (2): 1 0.008 V 2 0e 2 t / R L C
0.9 CVC2 0 2 C
dt
2 0 Rchest
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 14
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Example (Cont.):
2 ( 0.008) / R L C
0.9 / e 1
2 ( 0.008) / R L C
0.0526 e
solving for C give: C = 54.3 μF
initial voltage across capacitor:
1
300J CVC 0
2
2
Vc(0)=3,322.90V
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 15
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Square Wave Defibrillators
Rlead
SCR2
power +
+ Load voltage regulated by
supply SCR1 thyristor (Silicon controlled
Vc Vchest Rchest
rectifier SCR).
C timing
_
circuit _
• during charging, SCR1 and SCR2 both open
• to defibrillate, SCR2 closes, current flows to chest Vchest
• after a fixed interval, SCR1 closes, shorts out C
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 16
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
(a) Basic circuit diagram for a capacitive–discharge type of cardiac defibrillator. (b) A
typical waveform of the discharge pulse. The actual waveshape is strongly
dependent on the values of L, C, and the torso resistance RL.
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 17
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
• Defibrillation process assessment:
• HR
• PR, RR interval stability
• more sophisticated electrogram analysis.
Example:
A defibrillator provides a 5 ms pulse of 20 A to a
50 load.
Thus the energy delivered is
E = P = I2Rt =
(20A)2(50)(0.005s) = 100
J.
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 18
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Automatic External Defibrillators (AEDs)
• Two modes of operation:
• Automatic: AED recognizes specific arrhythmias via
signal processing algorithms, applies shock as needed.
No manual control.
• Semi-automatic: operator must confirm shock advisory
from AED to deliver the shock.
• Less operator training needed
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 19
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Automatic External Defibrillators (AEDs)
LIFEPAK 500 Automatic
External Defibrillator
(AED) weighs 3 kg and is
portable (Medtronic inc.
2001).
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 20
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Defibrillator Electrodes
• Usually from metal, 70-100 cm2 surface area
• must be coupled to skin using conductive material (otherwise can
burn patient)
Two types of electrodes:
• Hand-held: conductive gel must be manually applied, reusable.
• Adhesive : adhesive conducting material holds electrode to
skin, disposable
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 21
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Hand-Held Defibrillators Electrodes
Electrodes used in cardiac defibrillation are in two shapes
(a) A spoon-shaped internal electrode that is applied directly to the
heart.
(b) A paddle-type electrode that is applied against the anterior chest
wall.
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 22
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Hand-Held Defibrillators Electrodes
Hand-held transthoracic electrode (From Tacker Jr. 1980).
Button
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 23
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Adhesive Type Defibrillators Electrodes
Some examples of the pre-applied adhesive electrodes (From
Tyco/Healthcare Kendall LTP 2001)
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 24
CHAPTER 7: Cardiac Defibrillator
External Defibrillators
Defibrillators Electrodes
Electrode Placement
anterior wall placement front-to-back placement
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 25
CHAPTER 7: Cardiac Defibrillator
CARDIOVERSION
• Cardioversion is also a shock supplied to treat other types of
arrhythmias such as:
• Atrial fibrillation
• Ventricular tachycardia (rapid heart rate)
• These types of arrhythmias are not life threatening but do
result in reduced cardiac output
• It is important that the cardioversion pulse not coincide with a
T-wave otherwise ventricular fibrillation may result.
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 26
CHAPTER 7: Cardiac Defibrillator
CARDIOVERSION
standby
power charge discharge
gate patient
supply
switch is under
operator control
energy timing ECG
storage circuitry monitor
applies shock about 20-30 ms
after QRS complex
Block diagram of Cardioversion
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 27
CHAPTER 7: Cardiac Defibrillator
CARDIOVERSION
DC Synchronized Defibrillators
In cardioverter, the
defibrillation pulse in
this case must be
synchronized with the R
wave of the ECG so that
it is applied to a patient
shortly after the
occurrence of the R
wave.
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 28
CHAPTER 7: Cardiac Defibrillator
Implantable Defibrillators
• Introduced for the first time by
Cardiac Pacemaker Inc (1985) in
USA
• Recommended for patients of high
risk for VF
• Usually combined with pacemaker
Implantable cardioverter defibrillator (ICD) (Medtronic inc., 2001).
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 29
CHAPTER 7: Cardiac Defibrillator
Implantable Defibrillators
• Treat v. fibrillation, tachycardia
• Usually incorporated as part of an implanted cardiac pacemaker
(typically VVI). Normally Biphasic wave is used
• Specifications:
• ~ 750V
• 30-35J
• Heart load ~ 50Ω
• Shock duration 4-8ms
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 30
CHAPTER 7: Cardiac Defibrillator
Implantable Defibrillators
Safety during defibrillation process:
• Operator should be careful not to touch
electrodes during defibrillation.
• Other personnel should remain clear of patient
and any metal objects contacting patient
during defibrillation.
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 31
The End…
Questions?????
12/11/2022 Biomedical Instrument-BME 460 Biomedical Systems and Informatics Engineering Department 32