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Document Analysis and Data Summary

The document discusses a patient with abnormal liver function test results including elevated levels of SGOT, SGPT, bilirubin, and bile salts/pigments. It recommends further tests and treatment to diagnose the cause of the liver problems.

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vishnu13141
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0% found this document useful (0 votes)
11 views63 pages

Document Analysis and Data Summary

The document discusses a patient with abnormal liver function test results including elevated levels of SGOT, SGPT, bilirubin, and bile salts/pigments. It recommends further tests and treatment to diagnose the cause of the liver problems.

Uploaded by

vishnu13141
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

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Kaumarbhritya II
The effect of Kanchanara Twak in the management of
Tundikeri (Tonsillitis) of the children
Name ' Dr. Bimal Kumar Panda
Guide ' Prof. C.H.S. Shastry
Co-Guide ' Dr. Moti Rai
' Dr. M.L. Gupta
Year ' 1997
Large prevalance of disease in the age group of 4-15 years and in
regular recurrance of disease compelled to take the present study. Tundikeri
is a large swelling at the root of palate which is associated with pricking
pain, burning sensation and suppuration due to vitiation of kapha and rakta

24
which gives much pain to the child and disturb his normal living hence an
attempt is made to give the child relief in his symptoms.

The present research work was carried on 45 patients of age group 5-


10 yrs. The trial drug was in the form of syrup, named Kanchanar syrup
which is prepared from dry Kanchanara tvak.

The criteria adopted for the assesment was subjective and objective
both. In the symptoms of Tundikeri both according to modern and ayurvedic
view were assesed under subjective criteria. In objective criteria the
dehaprakriti, dosha, dushya dhatu, adhisthana desha, kala, kostha, nadi,
natural signs and symptoms were assessed and according to modern
concept-Hb%, TLC, DLC, ESR, Throat swab culture/sensitive test, C-
reactive protein (CRP) test, Anti streptolysin "O" titre (ASLO) were
assessed.

The trial patients were grouped in 3 groups - Group A : Treated group


given Kanchanar syrup 5-10ml t.d.s. with luke warm water for 1 month.
Group B - Standard group given Amoxycillin 25-50 mg/kg of body wt./day
t.d.s. for 10days. Group C - Placebo group given Sugar syrup 5-10ml t.d.s.
for 1 month.

After the trial there was 46.66% result showed in remission, 40% in
partial remission and 13.33% no remission in group A. 73.33% and 26.66%
result showed in remission and partial remission in group B and 60%, 40%
result showed in partial remission and no remission in group C respectively.

25
IM
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26
Kaumarbhritya IV
A Clinical study on Gokshur Siddha Yavagu and Dhatryavaleh
on Fetus in cases of Toxaemia of Pregnancy
Name ' Dr. Renu C. Mohta
Guide ' Prof. C.H.S. Shastry
Co-Guide ' Dr. Geeta Sharma
Year ' 1998
Toxaemia of pregnancy is common. It appears to be largest, single
cause of feto-maternal morbidity and mortality. It is mandatory to evaluate
the action of Gokshur Siddha Yavagu along with Dhatryavaleh and rules of
garbhini paricharya to see its curative action on disease entity.
Total 30 cases had been registered between the age group of 15th to
45th year having 20 weeks onwards gestation and two group in which, one
control group with plain mudga yavagu 100 gm b.d. with anupan of water
and simple avaleh (ghrit, honey, ela powder & thready pak of sugar) 100gm
b.d. with anupan of milk in 15 cases and another group with trial drug.
Gokshur Siddha Yavagu (Gokshur 10gm and yavagu was made by mudga)
100 gm b.d. with anupan of water and Dhatryavaleha ([Link]. 16/100)
10gm b.d. with anupan of milk in 15 cases. The duration of treatment was 15
days.
In control group, all the patients except two had shown deterioration
in the condition. In trial group 66.6% patients have received excellent
response while 33.4% got good response. Thus it could be concluded that
both Gokshur Siddha Yavagu and Dhatryavaleh administered right from the
4th month of pregnancy can prevent the incidence of pre-eclampsia
(Toxaemia) and super imposed eclampsia.

27
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29
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Kaumarbhritya IQ
Effect of some indigenous drugs in Balatisara

Name ' Dr. Syamal Deb


Guide ' Dr. Vijay Laxmi
Year ' 1999
The problem of diarrhoea in pediatric practice is almost of daily
occurrence. This disease is one of the main cause of infantile mortality
and morbidity because a child may loose almost as much water as an
adult. Childhood diarrhoea is mainly a crucial problem of developing
countries like India due to poor sanitation, lack of health knowledge
and low socio-economic status. Due to usual recurrence child becomes
severely malnourished and it leads to different ailments. Due to
common occurrence and serious complications this subject was chosen.
Total 36 patients were studied up to age group of 15 years.
Patients were divided in two groups. Group A was named as treated
group and group B as control (placebo) group.
A compound Balatisarahara Yoga (Ingredients – Dadim
phaltwak, Nagkesar, Shwet jirak and Gaja pippali) was used in the form
of syrup in treated group for 7 days and dose was decided 4 ml/kg of
body weight/day in divided doses.
In Investigations mainly stool test for colour, odour, mucous,
parasites, ova/cyst, reaction (pH) were done.

30
After treatment the average improved % of treated group was
75.38% and not improved percentage was 24.62%. In control group the
average improved percentage was 15.83% and not improved percentage
was 84.17%. Hence conclusion comes out that drug compound named
Balatisarahara Yoga can be used effectively in the management of
Balatisara.
Kaumarbhritya IB
Efficacy of Snuhi Kshara and Haridra on Pharyngitis in
children
Name ' Dr. Rakesh Kumar Gaur
Guide ' Dr. Vijay Laxmi
Co-Guide ' Dr. Moti Rai
Year ' 1999
The upper respiratory tract infections are quite commonly
prevailing among children especially in India. Pharyngeal involment in
most URTI and is found with various acute generalized infection,
similar condition are also described in ayurvedic classics under
Kanthagata rogas like vrinda and ekvrinda. Present study has been
planned to manage this problem by drug – Snuhi Kshara and Haridra.
The study was conducted on 20 patients. Clinical criterias were
cardinal feature of Pharyngitis (e.g. sore throat, dysphagia, irritating
cough, fever etc.) and objective criteria included Throat swab culture,
ESR, Leucocytes count. Drug was prescribed in the dose of 3 ml twice
daily through spray in the throat for 15 days.
The study revealed highest incidence in the age group of 6-15
years and higher incidence was found in vatakaphaja prakriti. After

31
treatment insignificant changes were noted in Hb gm % and
Polymorphs while in ESR and TLC significant and highly significant
changes were recorded respectively. Moderate improvement was noted
in Throat swab culture, 66.6% cases showed change in Throat swab
culture from positive to negative. Analysis of total severity of clinical
features have shown remarkable improvement in almost all associated
features. Observation revealed that 15% cases were got excellent
remission, in about 65% cases good remissions (50 to 75% relief in
severity) was found, while partial remission (25 to 50% relief in
severity) was recorded in 15% cases, only 5% cases were concerned to
no remission group.
This study is suggestive that Snuhi Kshara and Haridra is quite
effective in Pharyngitis.
Kaumarbhritya I+
Comparative study on the efficacy of Balachaturbhadrika in
different disorders of children
Name ' Dr. Dharmendra Kumar Sharma
Guide ' Dr. Vijay Laxmi
Co-Guide ' Dr. Abhimanyu Kumar
Year ' 2000
Children usually suffer with the common ailments like
malnutrition, atisara, jwara, kasa, swasa & chhardi. India being a
developing country the nutritional status of major children population
is very poor which lay down foundation for nutritional deficiency,
infections, acute respiratory disorders, diarrhoeal diseases etc.
Balachaturbhadra, the drug chosen for the research is especially

32
indicated for the childhood ailments, the research work is commenced
to test the efficacy of the chosen drug in different childhood diseases.
No. of patients chosen for the study were 65 in the age group of 4
months to 10 yrs. the patients were divided in two groups.
Group A – 35 patients – Balachaturbhadrika syrup
Group B – 30 patients – Sugar syrup
The ingredients of the Balachaturbhadrika are Ativisha, Mustak,
Pippali, Karkatshringi.
Dose – 1 ml/kg of body wt./day individed doses and duration of
trial was 7 days.
Drug result showed good response in jwara (group-A 80%, group
B-31.81%), in case of kasa, response was noticed as mild to moderate
improvement. Moderate response was found in paittika kasa (group A –
60%, group B-14.48%), as well as kaphaja kasa (group A-75%, group
B-30%).
The drug has shown good response in following features like
associated with - chhardi, greater incidence like headache, salivation,
anorexia, pain in cardiac region.
The drug has good response in paittika atisara (group A-80%,
group B-28.57%), while the response in vatika atisara was good and it
was moderate in Kaphaja variety.

33
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Kaumarbhritya MM
Study on the role of Triphala Rasayan in Morbidity pattern of
children

Name ' Dr. Deepti Ahuja


Guide ' Dr. Vijay Laxmi
Co-Guide ' Dr. Abhimanyu Kumar
Year ' 2001
Morbidity has been defined as "any departure subjective or
objective, from a state of physiological well being". Nutritional
deficiencies, gastro-intestinal and respiratory ailments are three major
disturbances which afflict the child and are responsible for the high
morbidity and mortality. The study is carried out to find the role of
Triphala Rasayan in morbidity pattern of children.

37
The clinical trial was done on 20 patients. Contents of Triphala
Rasayan drug are Amalki, Vibhitaki and Haritaki. The drug has been
prepared in the form of syrup. Dose of medicine – 1 ml/kg of body
weight/day in 2 divided doses for 3 months. Routine blood
investigations have been carried out.
As incidence of running nose, cough and fever were found higher
previously and after the treatment the drug was found more effective in
above mentioned features. The incidences after 3 months in above
features were 50%, 65% and 35% respectively. Incidences of sore
throat and LRTI were 20% and 10% respectively after treatment.
Kaumarbhritya MV
Study on Medhya effect of Jyotishmati in Borderline Mentally
Retarded children
Name ' Dr. Hema S. Kolhe
Guide ' Dr. Vijay Laxmi
Co-Guide ' Dr. Abhimanyu Kumar
Year ' 2001
A person will be called mentally retarded who has I.Q. less than
70 with difficulty in adoptive behaviour which is manifested before 18
yrs. of age. Mental retardation is a social problem of great magnitude as
well as the problem faced by the parents of such child is beyond limit.
The drug used for the research work was Jyotishmati, in the form
of syrup in the dose of 4-5 drops daily for 3 months. Total no. of
patients chosen were 68 in the age group of 6-12 yrs. The patients were
grouped as below –

38
1. Group BT – Borderline mentally retarded children who were
treated.
2. Group BT – Borderline mentally retarded given placebo.
3. Group NT – Children with normal IQ who were treated.
4. Group NT – Children with normal IQ given placebo.
There were 17 patients in each group.
Sample of 68 children was further stratified into 2 categories i.e.
BMR category and normal category as per their IQ level. They were
further divided into a treated and a placebo group as above.
The results showed that maximum patients belonged to age group
8-12 yrs. with male prominence. Maximum cases were from UKG upto
IV class belonging to lower socio-economic status with poor parental
education. After 3 months of trial there was a significant gain in IQ
score in BMR treated group as well as in normal IQ treated group
compared to placebo group. Therefore, it can be concluded that drug is
beneficial both in borderline mentally retarded as well as normal
children.
Kaumarbhritya MR
Effect of Lavang Chatuhsam in Balatisar
Name ' Dr. Reena Pandey
Guide ' Dr. Vijay Laxmi
Co-Guide ' Dr. Moti Rai
Year ' 2001
Balatisara is a common problem in childhood mainly showing its
presence in the developing countries due to poor hygiene and low
socio-economic status like India. It leads to many diseases like

39
Balshosha and make the child unable to thrive properly, due to its
common presence and dreadful results this topic was chosen.
In the yoga Lavang Chatuhsam there are 4 drugs named Jayaphal,
Sweta Jeeraka, Lavanga and Tankan. It was used in the form of syrup.
Total 60 patients were taken and divided into 2 groups. Patients were
taken based on subjective and objective criteria. In investigations
mainly stool test for ova, cyst, parasite, reaction (pH) and blood were
undertaken. Dose of yoga Lavang Chatuhsam was decided on the basis
of wt. of patients weighing between 3-6 kg. were given 2 ml t.d.s.
Patients weighing between 6-9 kg. were given 4 ml t.d.s. and above 9
kg were given 5 ml t.d.s. Total duration of medicine was of 7 days.
After treatment the average improvement seen in group A was
84.95% and in group B was 36.82%.
Hence conclusion comes out that Lavang Chatuhsam can be used
effectively in the management of Balatisar.
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Kaumarbhritya M+
Study on the efficacy of an Ayurvedic compound in the
management of some common Respiratory ailments of children

Name ' Dr. Sandhya Tuppekar


Guide ' Dr. Vijay Laxmi
Co-Guide ' Dr. Abhimanyu Kumar
Year ' 2002

43
In childhood respiratory tract disease is a common problem. 30%
of total admissions in pediatric hospital are due to respiratory
complaints and 15% of total deaths during childhood from age of 1-5
years are due to respiratory infections. So due to the recurrence and
common presence this topic was considered for research.
A drug compound named Top-C mainly having Guduchi, Tulsi,
Haridra and Pippali was used in the form of granules. Dose was decided
1 gm/kg of body weight/day in the divided doses for 3 months. 40
patients were taken in the two groups (Management group & prevention
group) in the age group of 1-5 years patients were taken on the basis of
subjective and objective criteria. In investigations Hb gm%, TLC, ESR
were done. Follow up was done fortnightly.
Drug Top-C compound has showed excellent response in
changing morbidity score of cough, running nose, expectoration, while
good response was observed in cases of dyspnoea, fever & sore throat.
Hence conclusion comes out that Top-C compound is very much
effective in the management of respiratory ailments in children.
Kaumarbhritya VT
Comparative study on the efficacy of Shringyadi Yoga in
different disorders of children
Name ' Dr. Anju Nagar
Guide ' Dr. Vijay Laxmi
Co-Guide ' Dr. C.M. Jain
Year ' 2002
Children are future of nation. It is indeed to be a better growth at
mental and physical level of them so, they will be free from disease and
make an healthy environment. Children are very delicate physically and
mentally. Some disorder related to GIT and Respiratory system as

44
jwara, kasa and chhardi are very common in them. According to
Chakradatta, the various disorder mentioned above can be successfully
cured by the Shringyadi Yoga which contain - Ativisha, Mustaka &
Karkatshringi.
In this study, the total 60 patients were taken in 2 groups. Group
A was treated with Shringyadi Yoga in the dose of 1 ml/kg of body
wt./day for 7 days and the group B was treated with placebo (Sugar
syrup), having 30 patients. During the treatment period patients were
assessed on 3rd , 5th and 7th day.
Subjective criteria was based on the clinical symptoms seen in
jwara, kasa and chhardi roga.
After completion of study improvement status of jwara in group
A - 90% & B-10%, in kasa group A-88.88% & B-16.66%, in chhardi
group A-50% & B-0% was found. No side effect of drug was found.
Observing the overall response of the trial drug, it was found that
relief in jwara, chhardi was good while moderate in case of kasa.
Shringyadi Yoga was found beneficial in jwara, kasa and chhardi.
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48
Kaumarbhritya VV
Study on the efficacy of Guduchyadi Rasayana in Learning
Disability of children

Name ' Dr. Geeta Rani


Guide ' Prof. S.K. Sharma
Co-Guide ' Dr. Abhimanyu Kumar
Year ' 2003
Learning Disability is the most common developmental disability and
estimated that 5-15% of all school going children suffer from this. It
includes problems of attention, memory, language etc. In ayuveda, Medhya
Rasayanas are used for this purpose.

96 patients of age group 8-12 yrs. were selected for study out of which
16 patients droped out. Study was conducted under 4 groups, 20 patients
each :

Group A - Only drug - Guduchyadi Rasayan (Chakradatta

65/24).

Group B - Drug + Behavioral and Psychological Intervention

and IEP (Individual Educational Plan).

Group C - Only IEP + Behavioral and Psychological

Intervention.

Group D - Given nothing.

The drug was syrup base given in dose of 0.5 ml/kg of body wt./day in
2 divided doses for 3 months.

49
Swarup Mehta Test for diagnosing L.D. child.

Mildly significant improvement was observed with research drug


(group A) in memory, inattention, hyperactivity/impulsivity and TTS
(Total), but result in these areas did not statistically differ from control group
D except in inattention (group A&D). Mildly significant improvement was
observed with IEP and psychological intervention (group C) in figure
ground (Selective attention), inattention, reasoning and TTS (Total). But
none of the difference between group C & D or other groups were
statistically significant. Group B showed significant result in figure ground.

Out of 19 assessments (including cognitive & ADHD) combined


therapy had mildly significant results in 4 areas viz. selective attention (FG),
memory, inattention and hyperactivity/impulsivity. Drug has more effect on
memory than IEP & counselling, as in memory group B had significant
differences from group C. Test drug alone is effective in improving
inattention.
Kaumarbhritya VR
Study on the role of Madhukadi Yoga in Vyadhikshamatva of
children

Name ' Dr. Sri Ram Chaubey


Guide ' Prof. S.K. Sharma
Co-Guide ' Dr. Abhimanyu Kumar
Year ' 2003
Frequent episodes of infection is one of the commenest cause of
disease & death, particularly in children. Increased susceptibility to infection

50
may result from a defect in the immune system, secondly immune system is
inactive in new born. For the prevention of recurrent infectious diseases
there is need to develop such a therapy which improve body immunity
specially non-specific immunity. In ayurveda, this concept comes under the
preview "Vyadhikshamatva".

For this study 30 patients of age group between 1 to 5 years were


taken. Following morbidity features have been taken i.e. running nose, nasal
obstruction, sore throat, lower respiratory tract infection, enlarged tonsils,
cough, dyspnoea, expectoration, fever & diarrhoea. Immunoglobulin G
(IgG) value and routine blood investigation has also been carried out for
assesment purpose.

Madhukadi Yoga was used whose ingredients were Yastimadhu,


Vacha, Pippali, Chitraka and Triphala. Form of the drug was ghana
(powder). Drug dose was 15 mg/kg of body wt./day in divided doses for 3
months.

Madhukadi Yoga is an effective recipe in reducing the incidences &


severity of fever, cough,sore throat, expectorant, dyspnoea, running nose and
lower respiratory tract infection. There was slight improvement in cases of
diarrhoea and nasal obstruction.

Statistical analysis of immunoglobulin G value & haemoglobin gm%


shown significant improvement after treatment. Slight reduction was noticed
in Eosinophil count after treatment but there was no remarkable finding
noticed in TLC, Lymphocyte and Neutrophil count.

The overall results indicated that Madhukadi Yoga is beneficial in


boosting up the Vyadhiksamatva in children.

51
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52
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53
Kaumarbhritya VB
Study on the role of an Ayurvedic compound in the
management of Balshosha (Protein Energy Malnutrition)

Name ' Dr. Suresh Kumar


Guide ' Dr. C.M. Jain
Year ' 2004
Malnutrition is broad spectrum and multi factorial major public
health problem in India. Children become more prone to infection due
to their low immunity status caused by poor nutrition. For this a
clinical trial is carried out to find the role of "AW compound" in the
management of Balshosha.

The main ingredients of the "AW compound" is Ashwagandha,


Shankhpuspi, Mandoorbhasma, Guduchi, Muktashukti, Shatavari,
Pippali, Madhuyasthi, Vidanga, Bala etc. AW compound was used in
the form of avaleha. Drug dose was 200 mg/kg of body wt. twice a day
for 2 months.

For this research 30 patients were selected of age 6 months to 6


years while 30 patients were divided into 2 groups of 15 each. In
subjective criteria clinical feature of Balashosha have taken and in
objective criteria Hb%, TLC, DLC, ESR, Serum protein were
investigated in the study. Assessment of the efficacy of drug has done
according to anthropometric reading before and after treatment. In
group A patient only standard diet was recommended and in group B
trial drug along with dietary advice was recommended.
Observation regarding clinical features after treatment showed
that in group A partial remission observed in arochaka, pratishyaya and

54
in shwasa and complete remission was not found in any patient. Where
as in group B complete remission was recorded in arochaka,
pratishyaya, jvara, kash, mukh snighdhata, mukh shuklata, shushkata &
in shwasa. It shows that clinical feature more subsided in group B than
group A due to dipan-pachan (Appetizer) etc. properties of drugs, so
the conclusion is that "AW compound" along with diet is highly
significant to treat Balshosha.
Kaumarbhritya V+
Study on Immunomodulator effect of an Ayurvedic compound
in children

Name ' Dr. Dhirendra Pratap Singh


Guide ' Dr. C.M. Jain
Year ' 2004
Great varieties of infectious microbes are present in our
environment e.g. viruses, bacteria, fungi, protozoa and multicellular
parasites. These microbes can produce diseases and leave less
permanent damage. This is due to immune system which combats
infectious agents. Today the nature has been disturbed by man and so
the defence mechanism of the body has also got impaired. In ayurvedic
text (Charaka Su. 28/7 Chakrapani Commentary) the term Vyadhi-
kshamatva described very well denotes body resistance against disease.
There are various immuno modulator drugs described under the
categories of Rasayan, Balya and Ojovridhikara drugs which are
responsible for enhancing the immune system of the body without any
toward effects.

55
A formulated drug named MYN compound was used, whose
ingredients mainly are – Madhuyasthi, Vacha, Pippali, Vibhitaki,
Amalaki, Haridra and Guduchi. The drug was administered in form of
granules. In clinical trial 30 patients were taken of age group 1-6 years.
Parameters taken to choose patients were subjective and objective.
Investigations include routine blood investigation, Hb gm%, Serum
immunoglobulin G (IgG). Dose of medicine was 10 mg/kg of body
wt./day and total duration was of 3 months.
The result in % are in running nose 10%, nasal obstruction
39.31%, sore throat 44.44%, lower respiratory tract infection 28.57%,
enlarged tonsils 28.57%, cough 6.66%, dyspnoea 53.84%,
expectoration 35.71%, fever 24.13% and in diarrhoea 54.54%. This
observation of all morbility features before and after treatment shows
that the result are highly significant and provides conclusion that the
drug is very much effective in increasing immunity.

56
Kaumarbhritya RT
Clinical study on the efficacy of a Medhya compound in
children with Attention Deficit/Hyperactivity Disorder (ADHD)

Name ' Dr. Triveni Kalar


Guide ' Dr. C.M. Jain
Year ' 2004
ADHD is one of the most common behavioural disorder in child
and adolescent psychiatry. It accounts for as much as 50% of child
psychiatry in clinical population. ADHD is a persistent problem that
manifests its core symptoms through out life cycle from preschool to
adult life. It interferes with a child's family, academic and social lives.
Several neuroanatomic and neuro psychological conditions have also
been correlated with ADHD viz. thinned and stretched corpus calosum,
EEG abnormalities and imbalance of certain neurotransmitters.
According to ayurveda any dysfunction in the chain of learning due to
imbalanced dosha at any subtle level will lead to abnormal production
of one or more types of innumerable types of buddhi. Balancing
(Harmonizing) the functions of tridosha and triguna is the main
treatment according to ayurveda.
For clinical study drug used was Memo compound having mainly
drugs mentioned in Medhya varga of Charaka.
Ingredients of Medhya compound coded as Memo compound :
(1) Mandukparni (2) Brahmi
(3) Shankhapushpi (4) Vacha
(5) Jatamansi (6) Abhaya

57
(7) Kustha (8) Vidanga
(9) Madhuyasti (10) Aswagandha
(11) Pippali.
Total 45 patients were taken and divided into 4 groups. All
patients were of age group 5-12 years. Patients were selected on the
basis of subjective and objective criteria. Grouping and treatment is as
follows.
Group M – 10 children, given syrup Memo compound only.
Group C – 10 children, given no drug only counselling of parents
and teachers was done.
Group CM – 10 children, given syrup Memo compound +
counselling
Group OO – 10 children, given no drug and no counselling
The drug syrup Memo compound was used 0.3ml/kg of body
wt./day in two divided doses for 3 months.
Mildly significant improvement was observed with research drug
in inattention (p<0.01), hyperactivity/impulsive (p<0.01). Significant
improvement was observed with counselling and psychological
intervention (group C) inattention (p<0.01), group CM showed mildly
significant advantage over group C, suggesting more effect of research
drug.
In scientific study ingredients have been found to possess
immunomodulatory, anti-oxidant, adaptogenic, digestive & normalizing
effect on neurotransmitters. Hence it has been concluded that Memo
compound is having very good results in the management of ADHD.

58
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59
Kaumarbhritya RI
Clinical study of an Ayurvedic compound (Arvindadi Yog) in
the management of Saiyyamutrata (Enuresis)

Name ' Dr. Sudha Singh


Guide ' Dr. C.M. Jain
Year ' 2005
Bed wetting (Enuresis) is a behavioural problem and the most
common chronic problem in childhood, next to allergic disorders.
Saiyyamutra is a disease of psychosomatic origin. Hence psychological
therapy along with drug therapy is thought to be the choice of
treatment.
Drug of choice was Arvindadi Yog, whose ingredients were –
Ashwagandha, Bala, Bal Haritaki, Kamal beej, Mandukparni, Brahmi,
Madhuyasti etc. and was administered in form of granules. Number of
cases were 30, in the age group of 5 to 15 yrs., divided into two groups.
Group A-Arvindadi Yog and group B-Arvindadi Yog + counselling.
Dose of the drug was given according to Clarks' rule, orally for 3
months.
Before treatment 73.33% patients had incidence 2-3 times per
night and 26.66% patients had incidence once/night.
After 3 months of treatment 53.33% patients had no incidence,
and rest 46.66% had incidence of once/night and after 6 months due to
remission of bed wetting only 20% patients had no incidence of bed
wetting. After 6 months the effect of Arvindadi Yog in group A showed
62.26% improvement, where as Arvindadi Yog along with counselling
in group B showed 69.17% improvement. Both were highly significant.

60
Kaumarbhritya RM
Role of an Ayurvedic compound (Krishnadi Yoga) on Vyadhi-
kshamatva of children
Name ' Dr. Vinay Kumar Singh
Guide ' Dr. C.M. Jain
Year ' 2005
Every year more than 80 million children are born in the
developing countries. Amongst them less than 10% only are protected
through immunization and about 5 million children die every year in
childhood due to contagious disease. Immunization have efficacy to the
limited disease and for recurrent infections rational use of antibiotics is
the need of todays. Therefore to prevent the recurrent infection, there is
need to develop such a therapy which can prevent the occurrence of
disease and enhance the immunity. That is alone reason to opt this topic
for research.
In present study Krishnadi Yoga was used, which was prepared
by adding five more drugs in Madhukadi Yoga mentioned in Sushruta
Sharira 10/50. The ingredients of Krishnadi yoga were - Madhuyashti,
Vacha, Pippali, Chitrak, Haritaki, Amalaki, Vibhitak, Haridra,
Guduchi, Tulasi, Vidanga & Bhumyamalaki. The form of Krishnadi
Yoga was in syrup to enhance pallatability, dose was 1 ml/kg of body
wt./day in divided doses for 3 months. For this research 30 patients in
the age group of 1 to 6 years were selected. Some clinical criteria as
running nose, enlarged tonsils etc. and laboratory criteria as Hb%,
TLC, DLC, ESR, IgG, Serum immuno-globin assay were adopted.
After 3 month's of treatment improvement was in running nose
16.66%, nasal obstruction 62.96%, sore throat 42.85%, LRTI 93.33%,
enlarged tonsils 47.05%, cough 13.33%, dyspnoea 90.90%,
expectoration 50.00%, fever 44.82% and in diarrhoea 100.00%.
Statistical analysis of morbidity were shows highly significant results
in the morbidity features excepts in fever which is significant.
Statistical analysis of Immunoglobulin G (IgG) shows highly
significant results.

61
Kaumarbhritya RV
Clinical study of an Ayurvedic compound (Somalatadi Yoga) in
the management of childhood Asthma
Name ' Dr. Deepak Saheb Rao Khawale
Guide ' Dr. C.M. Jain
Year ' 2005
Asthma is the most common chronic lung disease and it may
present at any age, but it is common in children and is leading cause of
chronic illness in children, responsible for a significant proportion of
school days loss. For this a clinical study of Somalatadi Yoga in the
management of Bronchial Asthma is proposed.
Ingredients of Somalatadi Yoga was – Somalata, Pushkarmula,
Vasa, Yastimadhu, Tulsi, Kantakari, Bharangi, Haridra, Sirish, Pippali,
Shunthi, Marich, Karkatshringi, Vibhitaki, Shati, Talishpatra, Balsudha
& was administered in form of syrup.
For clinical trial no. of cases were 30 in the age group of 1-12
years. Both subjective and objective parameters were taken for
assessment. Dose of medicine was 1 ml/kg of body wt./day and the
duration of treatment was 2 months.
In subjective morbidity features of Bronchial Asthma were taken
and in objective Hb%, TLC, DLC, ESR, TEC & Spirometry were used.
Statistical analysis of morbidity feature shows highly significant result
in coughing and sinus, while significant result were found in dyspnoea,
wheezing, activity, accessory muscles use, sleep disturbance and
insignificant result were observed in orthopnea and restlessness.
Marked improvement were observed in TEC, Lymphocytes, Hb% and
PEFR.

62
Kaumarbhritya RR
A Clinical study on the Anabolic (Brimhana) effect of
Bhringarajasava in children
Name ' Dr. Jakkula Snehlata
Guide ' Dr. C.M. Jain
Year ' 2005
The present clinical study on the anabolic effect of
Bhringarajasava in children helps for treating Apatarpanjanya vikaras.
The anabolic drug plays a vital role in promotion of tissue growth and
have much importance in the treatment of under wt. children and other
wasting diseases.
No. of cases 40, underweight children of age group 1-16 yrs. of
both sexes were selected for the study and divided into 2 groups A & B.
Group A patients were given balanced diet and group B patients were
given regular diet with Bhringrajasava (Gada Nigraha Vol. 1, 6/209-
212) according to body weight of children ½ hr. after food with equal
quantity of water. The treatment duration was 3 months. For assessment
both subjective and objective parameters were taken.
Observation regarding the morbidity features after 3 months
treatment showed that in group A there is good response in anorexia,
falling of hair, pallor and emaciation of body and there is no response
seen in other remaining features, but in group B excellent response seen
in cough, dyspnoea, insomnia, fever, dryness of skin, falling of hair,
spleenomegaly and there is better response seen in anorexia, giddiness,
pallor, hepatomegaly and emaciation of body.

63

Common questions

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The sources describe various Ayurvedic treatments differing in dosages and administration forms. For pharyngitis, Source 2 used a 3 ml spray dose twice daily. Balachaturbhadrika syrup was given at 1 ml/kg body weight per day in Source 2. Top-C granules were administered at 1 gm/kg body weight per day for three months in Source 3, whereas the AW compound was given at 200 mg/kg twice a day for two months in Source 4. These variations highlight tailored approaches based on specific treatment goals and patient demographics .

The trials evaluated using both objective and subjective measures. Objectively, metrics such as throat swab culture, ESR, TLC, and Hb% were used to gauge physiological changes . Subjective measures included the evaluation of clinical symptoms severity, such as relief in cough, fever reduction, or remission from malnutrition symptoms. These metrics provide a comprehensive assessment, combining quantitative data with qualitative patient-reported outcomes to measure treatment efficacy effectively .

The document highlights numerous challenges in developing countries, such as high incidences of nutritional deficiencies, infections, and respiratory ailments among children. These issues are compounded by limited healthcare resources and poor sanitation, raising the prevalence of common yet severe diseases like malnutrition and respiratory infections. The studies underscore the need for affordable and accessible treatments, like Ayurvedic compounds, that cater to prevalent community health issues, suggesting Ayurveda as a complementary approach to conventional treatment .

Demographics play a critical role in the studies from Source 2, particularly regarding the age group, which impacts the incidence of illnesses and treatment outcomes. For instance, the highest incidence of pharyngitis was in the 6-15 year age group, influencing treatment focus and assessment criteria. Understanding demographic factors is crucial for tailoring treatment and predicting intervention success, thus enhancing the study's relevance and applicability .

The Ayurvedic approach in Source 4, using AW compound, focuses on holistic treatment by combining dietary advice with herbal compounds like Ashwagandha and Shankhpuspi, emphasizing improving digestion and immunity through Rasayan (rejuvenation) properties. In contrast, conventional medicine might focus on direct nutritional supplementation and managing symptoms, lacking the emphasis on holistic wellbeing and preventive health inherent to Ayurveda. The Ayurvedic strategy aims to achieve balance and recovery through body systems enhancement rather than symptom suppression alone .

The study in Source 2 found that Balachaturbhadrika was effective in treating various childhood disorders. In jwara (fever), Group A (Balachaturbhadrika) showed an 80% improvement compared to 31.81% in Group B (control). In kasa (cough), moderate to good responses were noticed, with Group A showing 60% improvement in paittika kasa compared to 14.48% in Group B, and 75% in kaphaja kasa compared to 30% in Group B. The drug also showed a good response in addressing symptoms like headache and pain in the cardiac region .

The study in Source 2 evaluated the efficacy of Snuhi Kshara and Haridra for treating pharyngitis using clinical criteria and objective measures such as throat swab culture, ESR, and leucocyte count. Patients received 3 ml doses twice daily for 15 days. The treatment showed significant changes in ESR and TLC, with moderate improvement in throat swab culture—66.6% cases turned from positive to negative. Clinical features saw remarkable improvements, with 15% achieving excellent remission, 65% good remission, and 15% partial remission. Only 5% experienced no remission .

Shringyadi Yoga, comprising Ativisha, Mustaka, and Karkatshringi, was found effective in treating common childhood disorders like jwara, kasa, and chhardi according to Source 3. The study indicates that this compound successfully alleviates symptoms and enhances health outcomes, corroborating traditional Ghakra texts that recommend Shringyadi Yoga for these ailments .

The Top-C compound demonstrated significant effectiveness in managing childhood respiratory ailments. Composed of Guduchi, Tulsi, Haridra, and Pippali, it was administered at 1 gm/kg of body weight per day over three months among two groups. The compound showed an excellent response in changing morbidity scores for cough, running nose, and expectoration, and a good response for dyspnea, fever, and sore throat. This indicates that Top-C is effective in reducing respiratory complaints common in childhood .

AW compound, incorporating Ashwagandha, Shankhpuspi, and other herbs, was pivotal in treating Balshosha by enhancing appetite and digestion. Administered at 200 mg/kg of body weight twice daily for two months, it showed substantial improvement in group B (AW compound with diet) compared to group A (diet alone). Complete remission was recorded for several symptoms in group B, unlike in group A, suggesting the compound's significant contribution to managing malnutrition in children when combined with diet .

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