SAFETY DATA SHEET

Creation Date 02-Jan-2015 Revision Date 18-Jan-2018 Revision Number 6

1. Identification
Product Name Ethylenediamine Tetraacetic Acid

Cat No. : BP118-500; E478-1; E478-10; E478-500; NC1065691; XXBP118-10KG;

NC1163901; XXE478-12KG; NC1253743
CAS-No 60-00-4
Synonyms 3,6-Diazaoctanedioic acid, 3,6-bis(carboxymethy; Acetic acid, (Ethylenedinitrilo)tetraacetic
acid; EDTA; Edetic acid; Diaminoethanetetraacetic acid

Recommended Use Laboratory chemicals.

Uses advised against Not for food, drug, pesticide or biocidal product use

Details of the supplier of the safety data sheet

Company
Fisher Scientific
One Reagent Lane
Fair Lawn, NJ 07410
Tel: (201) 796-7100

Emergency Telephone Number

CHEMTRECÒ, Inside the USA: 800-424-9300
CHEMTRECÒ, Outside the USA: 001-703-527-3887

2. Hazard(s) identification
Classification
This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200)

Acute Inhalation Toxicity - Dusts and Mists Category 4

Serious Eye Damage/Eye Irritation Category 2
Specific target organ toxicity - (repeated exposure) Category 2
Target Organs - Respiratory system.

Label Elements

Signal Word
Warning

Hazard Statements
Causes serious eye irritation
Harmful if inhaled
May cause damage to organs through prolonged or repeated exposure

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Precautionary Statements
Prevention
Use only outdoors or in a well-ventilated area
Wash face, hands and any exposed skin thoroughly after handling
Wear eye/face protection
Do not breathe dust/fume/gas/mist/vapors/spray
Response
Get medical attention/advice if you feel unwell
Inhalation
IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
Call a POISON CENTER or doctor/physician if you feel unwell
Eyes
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
If eye irritation persists: Get medical advice/attention
Disposal
Dispose of contents/container to an approved waste disposal plant
Hazards not otherwise classified (HNOC)
None identified

3. Composition/Information on Ingredients
Component CAS-No Weight %
Ethylenediamine tetraacetic acid (EDTA) 60-00-4 > 99

4. First-aid measures
General Advice If symptoms persist, call a physician.

Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.
Obtain medical attention if irritation persists.

Skin Contact Wash off immediately with plenty of water for at least 15 minutes. If skin irritation persists,
call a physician.

Inhalation Move to fresh air. If not breathing, give artificial respiration. Get medical attention if
symptoms occur.

Ingestion Clean mouth with water and drink afterwards plenty of water. Get medical attention if
symptoms occur.

Most important symptoms and None reasonably foreseeable.

effects
Notes to Physician Treat symptomatically

5. Fire-fighting measures
Suitable Extinguishing Media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Unsuitable Extinguishing Media No information available

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Flash Point Not applicable

Method - No information available

Autoignition Temperature Not applicable 200 °C / 392 °F

Explosion Limits
Upper No data available
Lower No data available
Sensitivity to Mechanical Impact No information available
Sensitivity to Static Discharge No information available

Specific Hazards Arising from the Chemical

Thermal decomposition can lead to release of irritating gases and vapors. Keep product and empty container away from heat and
sources of ignition.

Hazardous Combustion Products

Nitrogen oxides (NOx) Carbon monoxide (CO) Carbon dioxide (CO2)
Protective Equipment and Precautions for Firefighters
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full
protective gear.

NFPA
Health Flammability Instability Physical hazards
2 1 0 N/A

6. Accidental release measures

Personal Precautions Use personal protective equipment. Ensure adequate ventilation. Avoid dust formation.
Environmental Precautions Do not flush into surface water or sanitary sewer system.

Methods for Containment and Clean Sweep up or vacuum up spillage and collect in suitable container for disposal. Keep in
Up suitable, closed containers for disposal.

7. Handling and storage

Handling Wear personal protective equipment. Ensure adequate ventilation. Avoid dust formation. Do
not get in eyes, on skin, or on clothing. Avoid ingestion and inhalation.

Storage Keep in a dry, cool and well-ventilated place. Keep container tightly closed.

8. Exposure controls / personal protection

Exposure Guidelines This product does not contain any hazardous materials with occupational exposure
limitsestablished by the region specific regulatory bodies.

Engineering Measures Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations
and safety showers are close to the workstation location.

Personal Protective Equipment

Eye/face Protection Wear appropriate protective eyeglasses or chemical safety goggles as described by
OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard
EN166.

Skin and body protection Long sleeved clothing.

Respiratory Protection Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard
EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if

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exposure limits are exceeded or if irritation or other symptoms are experienced.

Hygiene Measures Handle in accordance with good industrial hygiene and safety practice.

9. Physical and chemical properties

Physical State Powder Solid
Appearance White
Odor Odorless
Odor Threshold No information available
pH 2.5 10 g/L (23°C)
Melting Point/Range 220 °C / 428 °F
Boiling Point/Range No information available
Flash Point Not applicable
Evaporation Rate Not applicable
Flammability (solid,gas) No information available
Flammability or explosive limits
Upper No data available
Lower No data available
Vapor Pressure 0.013 hPa @ 20 °C
Vapor Density Not applicable
Specific Gravity 0.86 @ 20°C
Solubility Slightly soluble in water
Partition coefficient; n-octanol/water No data available
Autoignition Temperature Not applicable 200 °C / 392 °F
Decomposition Temperature > 150°C
Viscosity Not applicable
Molecular Formula C10 H16 N2 O8
Molecular Weight 292.23

10. Stability and reactivity

Reactive Hazard None known, based on information available

Stability Stable under normal conditions.

Conditions to Avoid Avoid dust formation. Incompatible products. Excess heat.

Incompatible Materials Strong oxidizing agents, Strong bases, Metals, copper

Hazardous Decomposition Products Nitrogen oxides (NOx), Carbon monoxide (CO), Carbon dioxide (CO2)

Hazardous Polymerization Hazardous polymerization does not occur.

Hazardous Reactions None under normal processing.

11. Toxicological information

Acute Toxicity

Product Information
Component Information
Component LD50 Oral LD50 Dermal LC50 Inhalation
Ethylenediamine tetraacetic acid 4500 mg/kg ( Rat ) Not listed 1 mg/l (rat)
(EDTA) >2000 mg/kg ( Rat )
Toxicologically Synergistic No information available
Products
Delayed and immediate effects as well as chronic effects from short and long-term exposure

Irritation Irritating to eyes

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Sensitization No information available

Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen.

Component CAS-No IARC NTP ACGIH OSHA Mexico

Ethylenediamine 60-00-4 Not listed Not listed Not listed Not listed Not listed
tetraacetic acid
(EDTA)
Mutagenic Effects No information available

Reproductive Effects No information available.

Developmental Effects No information available.

Teratogenicity No information available.

STOT - single exposure None known

STOT - repeated exposure Respiratory system

Aspiration hazard No information available

Symptoms / effects,both acute and No information available

delayed

Endocrine Disruptor Information No information available

Other Adverse Effects The toxicological properties have not been fully investigated.

12. Ecological information

Ecotoxicity
Contains a substance which is:. The product contains following substances which are hazardous for the environment. Toxic to
aquatic organisms.

Component Freshwater Algae Freshwater Fish Microtox Water Flea

Ethylenediamine tetraacetic EC50: = 1.01 mg/L, 72h LC50: 44.2 - 76.5 mg/L, 96h Not listed EC50: = 113 mg/L, 48h
acid (EDTA) (Desmodesmus static (Pimephales Static (Daphnia magna)
subspicatus) promelas)
LC50: 34 - 62 mg/L, 96h
static (Lepomis macrochirus)

Persistence and Degradability Soluble in water Persistence is unlikely based on information available.

Bioaccumulation/ Accumulation No information available.

Mobility Will likely be mobile in the environment due to its water solubility.

13. Disposal considerations

Waste Disposal Methods Chemical waste generators must determine whether a discarded chemical is classified as a
hazardous waste. Chemical waste generators must also consult local, regional, and
national hazardous waste regulations to ensure complete and accurate classification.

14. Transport information

DOT Not regulated
TDG Not regulated
IATA Not regulated
IMDG/IMO Not regulated
15. Regulatory information
All of the components in the product are on the following Inventory lists: X = listed

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International Inventories

Component TSCA DSL NDSL EINECS ELINCS NLP PICCS ENCS AICS IECSC KECL
Ethylenediamine tetraacetic X X - 200-449-4 - X X X X X
acid (EDTA)
Legend:
X - Listed
E - Indicates a substance that is the subject of a Section 5(e) Consent order under TSCA.
F - Indicates a substance that is the subject of a Section 5(f) Rule under TSCA.
N - Indicates a polymeric substance containing no free-radical initiator in its inventory name but is considered to cover the designated
polymer made with any free-radical initiator regardless of the amount used.
P - Indicates a commenced PMN substance
R - Indicates a substance that is the subject of a Section 6 risk management rule under TSCA.
S - Indicates a substance that is identified in a proposed or final Significant New Use Rule
T - Indicates a substance that is the subject of a Section 4 test rule under TSCA.
XU - Indicates a substance exempt from reporting under the Inventory Update Rule, i.e. Partial Updating of the TSCA Inventory Data Base
Production and Site Reports (40 CFR 710(B).
Y1 - Indicates an exempt polymer that has a number-average molecular weight of 1,000 or greater.
Y2 - Indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactants
that comprises one of the eligibility criteria for the exemption rule.

U.S. Federal Regulations

TSCA 12(b) Not applicable

SARA 313 Not applicable

SARA 311/312 Hazard Categories See section 2 for more information

CWA (Clean Water Act)

Component CWA - Hazardous CWA - Reportable CWA - Toxic Pollutants CWA - Priority Pollutants
Substances Quantities
Ethylenediamine tetraacetic X 5000 lb - -
acid (EDTA)

Clean Air Act Not applicable

OSHA Occupational Safety and Health Administration

Not applicable

CERCLA

Component Hazardous Substances RQs CERCLA EHS RQs

Ethylenediamine tetraacetic acid (EDTA) 5000 lb -
California Proposition 65 This product does not contain any Proposition 65 chemicals

U.S. State Right-to-Know

Regulations
Component Massachusetts New Jersey Pennsylvania Illinois Rhode Island
Ethylenediamine X X X - -
tetraacetic acid (EDTA)

U.S. Department of Transportation

Reportable Quantity (RQ): N

DOT Marine Pollutant N
DOT Severe Marine Pollutant N

U.S. Department of Homeland Security

This product does not contain any DHS chemicals.

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Other International Regulations

Mexico - Grade No information available

16. Other information

Prepared By Regulatory Affairs
Thermo Fisher Scientific
Email: [Link]@[Link]

Creation Date 02-Jan-2015

Revision Date 18-Jan-2018
Print Date 18-Jan-2018
Revision Summary This document has been updated to comply with the US OSHA HazCom 2012 Standard
replacing the current legislation under 29 CFR 1910.1200 to align with the Globally
Harmonized System of Classification and Labeling of Chemicals (GHS).

Disclaimer
The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the
date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage,
transportation, disposal and release and is not to be considered a warranty or quality specification. The information
relates only to the specific material designated and may not be valid for such material used in combination with any other
materials or in any process, unless specified in the text

End of SDS

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