Experiment = 4. _ “Te prepare and submit” paracetamal paedis “Elinte fF. Se iia lad oad it Reference: Sanmathi BS Mehta KK Aon wpe oaual dupa pny _ edition, Phar p. Sa fderabad. “i Pg No. 46 to 44 _ i Prop tne 9 col is used asa co- solvent ,to ineréade the | olubitity of paracetamo. “Therefore to mask this taste, invert s Yis_ pn ee aan al sgt aac por pte, [ e, © Glycerine _is used to increose the vi cosity —__| of the prepa ration and also acts ag ——Thumectant and gives soothing effect. i = Teacher's Signature :__k R Paracetamol Ethanol (46 7.) Propylene Glycol Conc. raspber juice Chloroform spirit Invert Syrup Amaranth solution Glyeriny.. qs: Fiat: Elixiy gr xxxvi f1.3 iiss FI.3 tiss M xxxvil ss M xxx RL.3 vit M iti Fl.3 xxv Mitte: [Link] ij Signa: Cochleare minimum mane et hocte capiendus. Type ‘Ingredients Raed was hea fe Rept imperial | Metric | patient | in tab Paracetamol 36 ay aby Heute g | 0.48 Mono- | Ethanol (961) 2B Ady! tom | 6 mt | 2m ‘ phasic | Propylene Glycol | 2:5 fdr] tom | 6 mi aml, ie ee Conc Taspberry Juice! 34-5 Mit 2-5 wat} 65 mt | od ml! Chloroform Spirit | 30 minim gan) Lom | o& wl Trvert Syrup Tidy | og mp | tg ml 5.6m Arnaranth solution! 3rninim) eg ml | 0.12 ml | 0.04" Glycerin. qs. [85 Fld lOom! | 60 ml aot} Make: Elixir Send: Go ml Direction: One ce to be taken, mornity | 4Procedure: DAccurately weigh the paracetamol! and dissolve _— tn_measured queintity of alcohol C961.) and propylene o Hlycol. eae ___@To “the above mixture ,add chloroform spitit invert jar and concentrated raspberry juice wwoith stir - sane ne! audit —__ @ Transfer this content toa measure, add amaranth ___ solution and make up the final volume with glycerine ___ @Filter if any foreign particles _or any ——__ ss “undissolved ‘subst@nces Tas ere Lenk on Dispensing: Transfer the elixir toa light resistant,norvow Dispensing) sistant n — mouthed, glass bottle, se it ti ghtly with | metallic screw cap, polish ound * lobel, dt - - - 7 Direction: One teaspoon to be taken, morning ond night: Storage: Store in_a_cool place aR ha ae Lobel : Label must bear all necessary requirements of liguid dosage forms ,meant for internal use. In addition, a TtheYamount of alcohol content used in the —— 7 “preparation shouldbe “mentioned on the label. Use, Parocetarnel pacdinbric elixir [_used_aa— Sos fan analgesic and antipyretic for_childeen.* Conversion factors» tion facto @ 1 fluid dracum = 4 mI @ ts grain = 4 gm ® 15 minim: 4 ml 4 @ 4 Fluid 02 = 30 ml. * Lobel: Paracetamol poesiorris Elixir I. [Link]) Paracetamo| Ethanol Propylene Glycol : 1 046g 2 ml ami Conc. raspberry juice : 0.5 ml Chloroform Spirit Lrvert suv Amaranth solution Glycerine -q.8:- ‘Lie No.: Aor Batch No: ol iMrp: XXK 10.4 mi | 6.6 ml 2 0.04 wml + 20 ml | | pH MPg Date: 20-09-23 | Exp Date: 20- 0g- 24 | Store in a cool. “Place. ‘Direction: One teas Poontyy | Use: Analg esic an rerning rae af be taken, | anti My by Stisha bate \Pyretic fo children Mfg Hep Maliba har Gnd Krishi Patel. | matey College, Tarsndi© xperivnent-2. ave ‘To prepare “end “submit simple symp. Reference: Sanmathi_| BS,Menta kK ,Gupta A, D jspensing. ph +O practical manual, 37% rd edition,_ Pharm Med Press. Press, Hyderabad , Pg No. 100 _to (Ol. fice Sica sy trated or nearly — 2 __~__ saturated “solution of Sucros oce_in purified Gattr. Tt contains 66.4: wlus of sucrose. tence the solubilis en lS rose, $ rm cae he ati a Sucrose is @ cara pared whi ch partially ____ hydrolyzed i a a iainemealr tae feewere uct) apd lappa Boece nies ee _dive _catled nd_rtaction is — catled as “Inversion” 4, ator tal — Teta 2 Dyce HO 9 Cet Og t CoH yy Og __ Sucrose Dextrose Laevulose — the inversion of sucrose is confirmed by __ i ppeasearin its optical rotation. After inversion, if th —_ leplution of sucrose rotates the polarized light to “he right side, then it is considered _as “dl exteo - lyotatery, If same solution rotates the - polarized Light to the left side then it is considered as (evo -rotatory.R Sacchart Aquam q:s- Fiat: Syrupi Type, Tngredtents More : iomenoee liquid for pharmact| Purified water 126 fidr atic | Make: Syrup 3xvisss 3 xxv Mitte: flioz ij Quant ity Guinntity Quontity duanty i 1 taken by! p mar | imperial! ¥ metric patient! te ab Tt 16-45 dy | 6tg A0.2q 13-4 (00 ml] €o mI | 20 ml: qs ; Send: 60 wl.Procedure +O Accura weigh sucrose and olissolve in 2 of total volume of purified water ino beaker. _@Heat this solution on a water bath with occasional Stirring, until whole amount of sugar completely ____dissolvés.(Do not do overheating) ———— ____ @Allow the solution tocol a Filter through ___ THe muslin cloth, to xtmove fortiqn. articles ,if— | pre seb Dispensing > Syrup “shou id_be always dispensed in do _bottles,_| ___ becaus e¢ Moistire coritent present in the wet —_ ‘pottle is sufficient to cause Fermentation. After preparation of syrup _it bould be cooled] 7 z room temperature, before Filling into the bottle a ce if ayup filled in to the bottle, it should be occasionally shaked until, hat attains room temperate Because moisture will condense or th inner side_o anes | pper part of the bottle These water molecules after a _Lrunning down, dilute the upper layers of the syrup, which Leads to fermentation of sucrose a : “Therefore transfer the symp to a well dried, — | neerrow_rnouthed, amber coloured, well Fil _bottle , close it thoroughly wi th plastic screw cap, nee! polish and label Sag fa agp le poapased_on_legaquntily then it aig! aaa ath eoatoned int loosely stoppertd _ — bottle, because plese entation takes place Carbon ioride oill liberate, pohich i rect# Conveuion factors * ® 1 dvacuum = 4 qm @ 1 fluid dracum = 4 ml @ 4 [Link] - 30 ml ¥ Lobel: ee Sirmple Syrup 7-P — Sucrose (3.49 Purified water..q.s ‘Lic No. : Ado! [Batch No: 02 i x xo ml | MFg Date: 24-09-23 | Exp Date: 24-09-23 | | | [Mrpixxe | [Store in a dark place ,at 25°C . |Use: Pharmaceutical aid. Mfg by : Misha Patel Mfg ot: Maliba Pharmacy College ,Tarsadi.— inside the_bottle_and mes “leads to bursting of container (ee J — Warm f lace favours the Permentation and C00 ol place induces s alization, therefore synus Teneo “Phir uy cant bap eratue ie | —trceeding 26°C 41 ae ‘Auiiliany + STORE AT FAIRLY CoOL TEMPERATURE ,NOT label” EXCEEDING #5°C IN DARK PLACE. Uses 5 Simple mup is used os a pharmaceutical aidl, i in the __ preparation of many pharticeutical products for the! | Following rem songs Tt has plaice sureet taste. Hence itis used as o_ Te ad aaiguoucabstageen | _ bitter az 7 @ Itis alco used aso vehicle for many ti liquid | ! oe ee ee a ec pe __@ Ins sucrose undergo hydrolysis into reducing sugars, as) __idextrase and Levulose which acts as anti-oxidants: Hence sy raf reduces ths ation of ee ee hpi ___|sufficient. be vec ceceiatave Dementia _osrnotic pressu. eit withdraws water frm the ricroor pele ood tends Ht dehy den __| finally death of microorganisms it_acttas Sq ot preservative" _ oa Teacher's SignatureExperiment 3. Te prepare and | A supp ly piperazine citrate — DATE finns: Sanvonta Bs _,Mehta } K K strap. A — Dispensing — — ohana. Med Prees Hyderabad Pg No. #4 to 5. Theory : Piperazine citrate acts acts ag anthelmmmtic. It __~isin salt form ond hence freely soluble in water. Therefore it doesn't requi € Qmount of aleshel The alcohol Which ig present i Spiti _ enous are h -alcoholic i y in itrate - \ pirit also act aa preservative: 2 | Glycerin act$ as a _co-Solvent to enon e the —___solubi of dru vi fect. ao | iPerazi itr i a 6 ; tu i Le and flav lagent like orange oil art used Yor masking the Lun pleasant taste:& Piperarinae citratis Spiritus Chloroformi Glyerim Olei auranti Syrupi Aquam-- 4S Fiat: Elixir Signa: Cochleare mi % ivss M viit £).3 iiss ae £1.38 xiiss f).3 xxv Mitte: [Link] nimum duo nocte Sumendum Type Ingredients Cuontity| duastity) Cuontity [Gusti — im 7) in Haken b ory imperial) metric | pati in [ab Mono- Piperazine citrate plasic Chloroform spirit Htiquid \for oral Glycerine [Link] | 18g 5.44 3.6 9 : g minim 0-5ml} 0-15 ml Oot mal 26 fdr} tOml| Seat | rl | use 0 nil | | |Oran \ 1S. +S. 18s BI easel Onenaect! (ance ides Ja esate pouaple syrup 12-5 £ldrl 5oml| tS ml | (Om | Purified ee 25 fldr| l00 mt] Jo mt | 207! I "Make: Elixir Send: 30 ml “Direction: Two teaspoonful to be taken at nighProcedure: OAccurate eis aa eine FT dissolve im alte igh the pipetntine citrate card 4 : OF purified woten —____ i -@ Dissolve oran e oil in chlornform spiritand odd tothe _ piperazine citrate solution, mix welt ____@ To the above soluti i ution,add simple syrup ond — _—glyceriny mix_uniformly. Th isconttnt to o __ measure ioind:adjuat the Final volume: twith purified user Dispensing: Transfer tae elixir to lig 4 resistant nor roi mouthed ___— glass ttle, close ik tig htl { etallic screw top, polish and lobel Dose _ ‘for treatment _of round worms, asa single lose up th f \ cco 0. i £ for children + 4-12 A ee eta ad 2 40.3 years = 5 ml | 4 to b yeors = 4.5 ral — [Econ 4 to 12 fears = 1o ml For treatment of Thread worms, 4 to 15 ml _ — daily in divided doses i given. Direction : Tusa teaspoonful to be taken, at night. Storage. : “Store ina cool place, re lee - ane Uses |; Piperazine citrate expels Hae round worms —__ thrtad worms fim the intestine therfore tae elixir is Used os anthelmintic: | jeacher’s Signature¥ Conversion factors @ 1 dracum = & gm @15 minimse 1 wl @1 fldy > ¥ Lobel: uml we Piperazine Citrate Elixiy IP. | Piperazine citrate 3.69 | Chloroform spirit 0.t ml | Glycerine 2QmI | Orange oil q:s- Simple symp loml | Purified Water-q.s-- 20 ml |Store in @ cool place. Direction: Two FeaspoonFul to be taken | at ni Use: Anthelmintic [Lie No. + A0ol Mq Date: 24-09-23 fl Batch No.:03 E 24-09- Imig: ee xp Date: 2-09-24 Mey by Misha Patel Mfg a :Matiba Pharmacy College, Tarsadi. ee aones prepart_ond Sie Tes -- | submit Aqueous == water im presence of potassium iodide. ____ Because Todine reacts with potarsitim— _ ——todide cuncl_Pornas_comele ex called au sl polyiodides A “These polyiodides pleas Lil a stable iodine ine KI +1, —— kKr.1, ( Potas ita monoiadide) ___|Ki + +21, ——> KL.21, (foto [er + tal. — —— KL. at, (Potassium tri iodide) | > KET, + KD2t thE BT KL. nl Ho Ke tn TY | Potassium +Todine Polyiodi ided Eee fodide Hi her pol ‘iodide: are more Soluble than | epee Polyiedide Therefore to aet higher = [poly iodides» ithe comnce nitrated solution { — prepared boy dissay) iodine and ide_im small portion of | water, then it is diluted ‘with theTodi Potassi lodidi Aquom...q.s ] Bis Bitss £3 RXV Fiat: Liquor Mitte? Plozi Signa: Cochleare amplum, omni nocte sumendum., j Type redients Ouonti ty Quantity Cuanti ty Quant [at tng | imperil mebric fakery! haa otytion| Todine 125 dy 5g 154 14 wwe) | [Potassium iodidel 2.5 dr (og 34 24 oe Purified water 25 fldr) | | es OO ml} 30 mi} 20 ml eee Moke: Aolution Djrection | 1 fend: 39 me Bigna ne tabled poonfus every wight ut to be taken af Eeefeature Weigh separately iodine ond polassium di Triturate . : , : one sHedine into Pine ponder in [Link]— ®Tn Oo benken, dissolve potassium iodide ae portion of water To Hau solution & wot lQaseaodiet Wien eae Telus ain al[Aqueous “Lodine Solution I.P. LAG OOK Todine tq | Potassium iodide 24 Purified water gS: 20ml lic No: Aool Mfg Date: 1-10-23 Bateh No:04 Exp Date :t1-19-24 [Mrp: xxx [Store in a cool and dark place. Use: For treatment of goitre. MPg My Misha Patel & Notnrahtel. Meg Oo ‘Maliba Pharmacy College Tarsadi. iret: One tablespoonfur enot evel A to be bd.el s o - ye UAE nsteaol muUdth, bu the py idotion or alogenattem off pets 8 veel protein a NOTE: © Todine staina a1 brown colour on the—skin, cloths ond containers mode up_ oh Pc eloin ond | metals. ae al tod Ln pent. Tt | oxidizea irom Conv tod .R xx vlis Citric acid monohydrate qr x S Concentrated amise woter qt ‘ett ss Uquor amaronthi ee Chioroformi Spiritus pied ew Syru pi “QS: . . Fiot: Linctus Mitte: floz.t Signa: Sip, Cochleave minimum et degiutiendus tente, bled. TT 7. ; se] 7 . Type | Ingredients Quantity Cuaartiy Quantity earl L imperial | metric poati lob. | Citric. acid SES are . A |: Honophai monohydrate (Sq) 2-59 | 0.459 | 0.59 jar oal Cone-amise water [5 minim 1m | O.3mt} o.2ml VAC Amaranth solution 22-5 minim (5 ml | 6.45 ml} 0.3 ml) iChloro form spirit | [1 minim, 6 mat {Sirm ple ogre 25 Sly) too mt | | L&mt | tam Boml| 2oml | Make: Linctus oul Boul ‘ | BignaDirection: Sip, one teas | | slowly , tuo Firmen a oy supasloy ooCpeniens e — DATE SS To prepare a) f Prep tnd subnit simple tinctus BPC. Teacher's Signature —® Conversion factors: @1s gre @ 15 minim 24 @ | thedr= & wy * Label: | a ID) - Simple Linctus Bec. | Citric acid monohydrate 0.5g Conc. amise water 0.2m) | Amaranth solution 0.3m | Chloroform spirit 1.2 ml] Sirnple SYMP--Gs-- 20 ml [Lic No: Avot Mfg Date: 1-10-23 patsuNes 05 [Exp Dote: 11-10-24 Store in a cool and dark place. | DO NOT DILUTE WITH WATER Direction: Sip, one teaspoonful and oo ees sloubigy buss iy | Use: For treatment of cough. Mfg by : Misho Patel 2 Namra Patel mg at : Maliba Pharmacy College Tarsad iDATE se Troms Pen he ae to a norrow moutted, aes eA Stant, gloss bottle, clede — + Sagal wits smetallio Acre Cae peluk" ard label, se S_po0ny tt and swallow asl nach d tore in aco oA potted Tre i lay ST TORE IN_A COOL AND DARK PLACE. Lobel's Do NoT DILUTE WITH wATER BEFORE USE: tBimple linetis is uted os demufeent = +h ector ont in the treat nremt of na - wenn Toachor's Signal;Experiment 6 DATE ar = cop dispense “ce eened watts Eevee le ca poo: 4 4 7 bee e| boadul? Dissolve potassium hidroxide in Vy te A af ed AD OL PH» ‘ Teachers SignatureR Cresol 1.3 iiss Vegetable oil A..3 ivss Potassi hydroxidi 3 i Aquam .@.5 [1.3 xxv Fiat: Liquor Mitte: floz it. Signo: Utendus, more dicto. —— uantity | Quantity Cuartt ty) Qusst | 7 dients a GP | green Hinapertadl| ncebtte,|* patie | ‘nctas (2.5Pldr 5 lo ml Pie Cresed oml| 30 ml jor | Ves etobte ol 45 Play (8 mi | (0.8 wal) 30m eee Mettler | 49 Joey] ota, | | Purified iceter 26 Pld (OOm!| 60 mi Do wil | og etek Salat i Make: solution Send: bom - | Direction: “To be uled, au dinected . eteaid. meal i ; the oboe mixtire Got Hh Prieta «| Ativrina | (Add tM ia 4 Content to Cu meat | —_| On At uLA Fin ok v Otte I ae [ if : eects Sirota Ee" SLOAN¥ Conversion Pactors :- 1dre 4 4 fidre G ml ¥ Lobet:- = Fare | _Cresol with Soap Solution. | | Cresol 10 mI Vegetable oul 3.6 mt Potassium hydroxide 0.8 g Purified water, 9.5. 20 ml ‘Lic No: Aool (MPy Date:18-10-23 Batch No. 06 I 5 -10- Mrp oxen, Exp Daterig 10-2 Store in a cool place. For EX TERNAL USE ONLY. Direction: To be Use: As a disin Ffectant, Mfg by :Misha Wed, a4 directed. Pater & Monn Patel Pharmacy Colleg eTarsodyy, FOR EXTERNAL US ONLY an tL US and hence camatic in Nord. tissug it. uk Co taed 1A_O a tae ot ortho, acta 3 i438 pecrotic_actian to Onimal tissug it - Ahold net be ued as Gmetinpee for Heir otn beings ‘Teacher's Signature LeExperiment <7. vi te aE A — leotution are tused eaaare otis , bi b ic if | icjent for complete nektralization. leh aciol acetre Acid , ae tod at F ; ——— Teachors SignatureR Glacial acetic acid Ammonium bicarbonatis ms Ammonium strong solution K1.3 ss Aquam qs FILB xxv FIL3 Kis % x 1s$S Fiat Liquer Mitte: [Link] i. i Signa: Cochleare amplum, bis indie Sumendum,) > Quostity Quast el mibric ate intab ‘Glacial Acetic acid | 11.25 Play 45mt) 2tmetl On| Aclution Ammoncunmn, | [. en bicarbonocis ae utg 829 449), uit Aromonie trong) Avution d 25 Far} Lomt | Gamat | 9 wl ( Punt pitel usoten | 9 | I 5 fl. I Ban shies Fade 100 my 380 ml Lol” | | Make: Aelution is 5 ae t . Om. | Dirtetion OfagePlespoon tusDATE H Co, 00 a > tH, ,COONH,, tH 0 +60."* Conversion factors: cee OLdr= y O 1 Fide Gynt. ' ¥ Labet:. ‘Strong Ammonium Acetate Solution I.P. GlacioP acetic acid Im Aramonium bicarbonate qu g Aromonium stron Solution d2™| Purified water, PQS... 20 mI Z ; lic No:A0Ol MPg Date: 18-10-23, [Batch No: 0% Exp Pate: 18-10-24 Store in a cool place. 7 | Dyertlon ome tablespoonful to be taken twic Le aus ; a A ee AS a diaphoretic and expectorant, Meg by: Misha Patel 2 Mann Patel | Mf at: Matiba Phar gees Pharmacy Celege, Taree,—2) Bre mothymel blur Givtsa— L -6~> -4£ b) Thana bles gies Yollour ot pH — Blut ot p= 1.6. Bromothymel blur indicates (ower link p= 4-6 and blue | tr_linmat YpH-§.0- Neutra Lizobi th | paint exis between _ [oH 4.6 bo £0 re pH LA mradntainedDATE giaciod Pat acid with continuo can ts ae ee a Uses ~_| ~_|r R aL xXx Soclii chloridi i i Sodii bicarbonatis Liquor amarantis “on x Aguam menthae piperitae qs: [Link]. x. Fiat? Collutorium Mitte: [Link] fi. Siqna*% Cum duplo aqua calidae aequoles, fn, Ulendum et rinse oris omni mane. se li Tupe | Ingyedients | [Cupatity Quantity] Cuontity used yp dd inn \Berial ae iene tre ty M ; jar 40 Aodium chloride Boqr | 5.3 B.l@q | 0.35 Tonophu J 9 J J usedonly Sod (ual vtl 40 gr 2.69 [-569 0.149); in mouth | r or buceed Amaranth (50minim) 3.3 ml} [98 wt} 0-22 mI > cov iby. Solution [ Peppermint) 10 Fz 300ml} 60 mI | 20m! WOttr---q-S- | elk Make: Mouthwaih Aend: bo Conall frection: Dilute With an rel of aaere wattr, before neva vine ta oi Le every ” morning. tha ™ ——_———- er ys | LP UAT aaExpuriment-§. o ane a - Ond dispense com ound Sodium chtoride mls ee angen spc : foe: Aonmotai Bc, Mehta Kol pel k., Anchu : Gupta, Dispensing pharmacy -a practical _—-manuol, 374 edi : med press, _—_ Hyderabad ‘ Pg no. 119-120 — feory: Tk 1s 0 mouthwosh containing sodium 1 i e, sodiumw chloride ata Sodium bicarbonate. Soditim chloride actt os | mM ion ou eon PAE TRToeT ER rere = eodorant antaci trols pH) & ie lone iL, stir lei _pep watth henrte mouth wash ts pre parcal bu im ple olution method J . 5Spe pepe wood Fo oa Ott the “tinal valu oa or +t ote Saree pottte close pear a FST _ iat plastic Screw Cap ; sn im a _coet place * FOR ExTERNAL USE ONLY *NoT To BE SWALLOWED, IN LARGE @UANTITIES. seat Compound sodima chloride naouth wail “ite aed to clean and deodorize Uo. buccal covity. Tt ia ae! used tp