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Genetics

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13 views80 pages

Genetics

Uploaded by

Vishnu
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF or read online on Scribd
‘Syemdics ! dui couned -by Batison . UM 1906 : } Gente, _ Study of “gen . } Shedy of horedily -ernel Vasrialions ) ) Prrnecply Inhuutone cand Vanialions ) > Youbis _, atindy 6 > (atuen) “| aia saluyitones 22» 8 ag tty > Awedit Vaniation » | : b » Aimilartus diffornes YL v Smbunitamee S (Tromsmission) > > itil Aeletion. -omd clemutioation of, amcbial, : wild Cows eg Sahiwal of Punjab ® ape 1BBY > Apuyor Mama eas 2 Fath oh Aynibies wits pleas IE, olan ee ’ fpr Fycars, > . Poste. » Dawin — Hms B Submissive ’ Solapagos IAlomd Introvert Ju edinny ine Stich , tolrowet , Nok Bolgist Profeoror ogpusive : Rutoresh ala Ceili Jere sy Locale on. Chrornsze7™ Ahremosome ¢ gems mods up 5 DNA. Gane > Chaemoseme => nucleus chuwteal matiane of gene ix DNA. Hl Physical basis oa Snkuulanee > garralis : my [Cremial bord ef nrvatonce > DNA - endl dvorked gn garden peo for Tyeons : 1922 - 198 ca law ef Qnbarttemes Precuduig’s : L Jatwirek Romain. unnoticad Se . = et CN ipllimiled ireatation % fowrnal Cocre y yr Welk war ahead 4 Home / wh _ Nok give prysioul prvr) of foctors (gem) Wied Slerlislics ame Matumalrcs dled in | p84. . - : 956 — potlilepiie ao ge pe we Lb - Shanna 4, jp unit lonhernlornee a 1409 Johansen prot Neretdian foal. eer Dantut oe 7 SE of Rediscovery f Mimolel 1s uote Gn) ° a 1900 3 WOkus Huge De Vatoy Holland Conk Corns Germarry Erich Yen Tchumak Mstivo. > > Reasons for Munclil’s aucceas Cam) Pisum — sadivum O Ahead pea plant for Meorimenty . @ Costly avoilanl, 4¥¥ y QAR eeageurere , ole. . eal ae py Pure. breading Aine : a Shot bile Abom rye self pMenation 3) large ong. of ad vbait * >) Both Auf y Goss polinadion - Toul Cursed with a TN > Aone enrrping bing wo linkage / Sneomplebe Daw nance Atuely oy om characte of a fome Morn height Tat / Owar, flower colowe oon ' a flewee position. a ah ee ee Suplaled] Comstricted P fed colowr ‘Green| apllow? Aud shape Roumd jrancaliteg ae Mellow | green Lamarck ae “pot eveluionary Adentst dandelion of evolution — gave Aum Biology. Te Lamorde 2+ Danwin —> Syears, Sveyages ” Hugo De Vrs Darwin Ovrpowered Mendl as vrtl as Alfreol Mdallace . “Alafegos Ssland — Buig Laborde Hemtyygout indinitual ie have Aimilan allel fou , Abeatfre otriuk - ) > tT be. ak 3® produ et kind o} > gomly CT, on 4,4) > . 3@ Possas ethu clominant Dy Acme altel, mower > both 3 Bo . »® Breed hue boo Apeetec > tri - ) Los E pa de Met have adalitionad , Vigew + disarnilon_ Ts 4 Two both have Ae Mondulian Now known as gue [Johanna 1904) is Mont a ‘unhuitanee , Helgi se Hy TIA DNA Lhiemosome ie y! ee pean arm Loud C positon) = as cchnompyons = sontiol contrat Chanactors Asmelo-geus thromoemy, Same shape, dine, Atrtohat Aang Same guna ok o position Aonboling some chareclin . ometis honteud. jpettphonli a J > D > > L 2 Gack game reetimesltacter stat game gate } > > ) Jametu are pure - : ; Bes CMe Atpanat, . peck Ag a Tt 14, 74,7 Low ef Dewsnames, ee pe gid tal v ; Try tt , Whur sAwo “genetically abipoont plans Are LnOsred l, Fy rosulk js abo ups Aybud TH. hybrid Always Aosombby tomar : © A characlin A, Aight ja sontrolled by a pain of footers (gins) ber dolls. — wre wok Lis ef ont chet. Gruption! —> Mubple aldals _ ger din tt Law ares ape ~ Plagemney, mer Sb eg - 44 human shin Colour (TBidyorid C02) . c ot Aegnegelt | ® during gownste fomatiion foots APD wey sipyolioh ¢ yak ¢ "o_o taaplion — untuonally oxaptid — No -eneeption ¢ — ALL plank ond avinala- : Low @} Dowinomer = ok universal é — \nos srtophows ¢ — Sweomplute Dominance ¢ - Codominomcy - : € € ¢ ‘ prunobype > Ltlineal aprpuoramee, umalype = snitvnal gual, ‘makeup Monshybrid ror Alindy 0) inhenclamee Hf ene thorecin nities Sr ‘bE vail \8 * Tait we uns 4f unit chanacdin oy J 8 an) ¥ pen tb Dhiw 0 aight SB. Mag > mus}. : gamnitis F gennration TH, Thy TEs Tt tow of dominance Wybrid TL a ° — Mw Yw YU eaUEeVNYVuv” “Tsk rors PE Rh Demivanst phimatjge Teak plat C Gunotype aunknoum)—(4) fo Ny Www Wud [Aybrid of Fr gor ene date noyy.o0 Viott Gx | WW x wor ue) Nar x wer at, Pemenigaus su Regssive ; gems WW ws, Wy Wr ae, aw Ram Ww, Wu, Ww, Ww Wor , Wie, with, woud : fol | Raw yrotst yw hate fut. ay flowers ine cv aan ; oy deprelation : dinknown flower A hamerygous i hefroyygows + clominamt , “Tesh sid, — To find gentle of clorinant Aysia of Fy captsed pith Ateussiue > > 2 2 2 > 2 a > 3 > 2 > > > ’ ’ , ’ ' Parunt RR x UL Red white gomti, RR nN, Fy gen Re, Ra, Re, Re E Pimk) Ru X Re 1 oy ro : R TRE ae Fa gen RR J Ra, Rn | Du iad Pink whee Tet Lew A 1 5 6 ® @ Wor | Wer w®W * Toa ss | wis AL vil fers re -hemeayeun lominentt eon fs Aitlisoyya ous AL fk An Rn x Re Ra, Rr Derninanee! ay yea pdiagon , Jvdiorhiuar , Jd Ra, L245 wr Colowe rower lover colo” Ruot RR y Ryk Figeit 74 oso IDR OER ALAA LA LALTATBARAADAPDAPNIPPONONDAM HARA am ~ Dihybrd 200 Grheritamer of Ave gem « Posumls YYRR yy tae ab Siaoned Poitk O gums yk, YR wpe pe th tin Fun YyRe , Yyhee PEED ie | sie gama fl ( 4 ¢ € 4 iy 4 Ee ak ws ! yR ne oo yh IS 5 Phometiypic sralio \ iad tn » YR Wy <* aN 3 gy “ sian i, als 5 oana trundle pia Whindeled = > 3 3 | 2 saps al ; P24 pea ey gy > > YR YYRR, YR YR Vy <0) | . 2 S. De 4 i oY, —, yy. : Ys we Yate @) {: % & WR Z ue : wie SE < Phandlypic retin 42 3.3: | Amalie role Lae Mina tbe Aru Apter yedlows 7 yon —— a? [) [e=. fi 38 J Ated Shape. Round } Assriinsled fa Bi | Law of Srdipemcnt Ataoninant OY 4 andepenalick of Bh @ fosulk of Dihybud ee ew wv UUvUHUHe ee ae Panacls BB SS bbss Block colewre Pa While colewr ‘Short Nair dong ait Gavutis BS, BS bs 7 b& Figen BbS& %, BbS& — Hybrud Block 4 het har | "== wewweuwvwvwevwvwvwrTwerwrr rer SSeS OTTO Bs Bs Black Block Aho: hath bong hase q 3 BBSS BBSs l 2 BRAS Bb as \ oy bbSSs bbSs \ 2 bbas | VS BDU etry 5 BLSS ! Sy BbSs Punnett appa 44408 (Rc ~ Punnett) Prema bic I graphical aypravnlation, a Fy Juegull 3" -probability / possi bilcly a of al the J 5. Statistical Analya%s, Phunety pte Aatio 34] ee 7 yoctpie sale Fea [bs 2 JLB I ee 4* 2° & Qs + 50 235] Benemial 2upussion (axtby)* = a+ Jab +b* Tt 4 atk + > (gis = ee 34) *l a TT Ate yd Ltt \ q y tide 1 | Rut ‘plicale Y y cS { Rut e Mattplicatton) British genedist | Reginad ©. Punactl ~ Atsro tlus mnethord fost aw [1925-| =. Sach oe eae Sop CS ai Andiviclral a te hl pole are. enlonid An mol > Ube vertical Squansr - Rurntining vXeb ome fil im by Combining the alleles of. ynake and fumake garnets, Advowtogs. dis in oninizaisiong the rary which corn OUP Am Avhon listing “Ol possible COM nrotiow 44 gowns et A Cee \reomplots coved namt Dihybsad AOSD Ugo rents TT RR mk On (Tau ped) ( dws shale) gama TR, TR dn, He Fy gun + TAR Tal -pink | Tek » TER gps TR Tae IR te ARR ducarf, Red de asl. Pink Tall Ave Tale pink. Tale whek 3 b 3 i Clon Hore deasart hit, ‘dh ( Tal : Th > Tod ‘ duo . durant - dura a) prk while Jed * pinks + usp Lhd 32.63 3° % Vout by y TA Red Tal pink Skin Red, \ 2 2 “Fatt whole Sako. Whe Qed pink 4 ! woe) au dusary perk usar} wh& J { TFL fad Tah pork Tal white Socban Pat Seda, pik | a \ a y anti ws dasa} nid. dung pre © dusong Aad \ pe \ THRn oy TAR TR TH AR be | ~ 2 TR Yeu tR | ae TTAR [rea Trea [eee z Tah ud | 7 ee oie de Red oo —f Pr Jrdvaradiak | < pak o \ ena Flower Latour an odtyay oclerats_ p- whit while cc EE Clee 9 CE Ce - e£ CcEe purple iss Cc&e X CcEe, | = [|Ccke |Ccee CE. | Clee CY | purple | uh | whee | white Oe he Me eve evvVveoeuogoUMwmwrmmacrmuaeraelNe Nee whi purpl QS. CS ythaaia of} Your rmatirial for purple pigment - Eo -> Aydin oh amypyme Hak conver Anu mobrial ivte puape pig ment - Oo l colo Chiermageyn Amys Hot coments Usernagon i nto dmtho tyanimn Cprsple pigment) [CCEE , ccte , CcFE, Se | cctt , Clee , Cet >» ceEe) soe mn b Bots CHE should be dominant Pr Purple - 4 ith ent BD Altesrive , plunolype b while « jyrg Dative, gnc wap : —— im Joserrtainsel aby ancy o Pregery a Individual - . Dm atone) Nei Tndeeendunt Spy worbolled by j 6 1 a ie % : Sutividaats having [eactets | ee? wy fame came phnolyrs [AY ae 4 jpaltvinucall i Atriduals with eee 2 alppemt soto, © prenotete may pray not Aant Pore ayer Same ahmolype - gomlype. . —Ereapiks emronte | Codeminange © Bsth attules fail 2 Expat thomas * eupres Mamselues Poy. AA AASIIIAI IIIA ALAA eww D Wiring of, rollin dn hybrif wo mig nid | ho ie Pee Err aan N We phevelype | tome Long get @) chow quatisainve bed ve Ain al Js indamabity foth aluly Berto 2 SH en ta phage obey’ Se ——————————— Mubliple altel CODOMINANCE Yi Blood apioups cin Auman peings population Loureption to Low af, und Chora and baw t Aowinence - Sn pebulation A, &, AB, 0 4 blood groups — sowtwlld by 3 alule | Muttiple alile - J =* 1 andi mary |yorious oltedes Ais auusre do both aS amd JP. TA amd 8 uthyn prumt Aogertter boty Litprrs alg? PB bled group, sodominant alts . sm: phnlype (() Possible genelypes (6 ) 1 A ime an 2 B 5 38 , => J 2 AB af 4% ~~ YP VUU DUT IOIOUD YUU PU OY OEP YEEE SS e—~——— ° c i = max: me of 6 genetyacs Ips 1, ihindape, C gonolupss ——__—. nab hear yhys i By it O mw possible panty AB Z A, 5,2 totiroo A X Jeli B ar & ed fs, © bo [ye Ajo jad A Ay . WAL za 2 bq Multiple allel ~ iene I LOSat & a gow pied ) LE Cit w Ah Agr lanolsteinen ~ Stuchigf bleed graups. ole Y Abeong = divcomeed AR bleay jr ae Asem Tas a Snlitlone Qreri ond Auttor . 1902. } Olt larity blw Mendel fa ~ ald tO Duster “ih poms Que jposurh en etveanelaet ae & Chadmoromes depanale (Amaphéoe 1) " 3. Non Aormoloous chremesemu ake indepenclemt of cock other + LA DASOMY, prt voorrionh of Mendelian ae Uremssemn mob gins Argradi y assert Jmdipomdinctly during yuieus . expanded 4. I Megan pprsend on chromesores a > Abite vant Chrbrnotored degegede 3 Brick 2s 4 other | chromosome jndipencimt AGL EREORAANRAATAATARAAAANA NANDA A 8 homologous (synap sus ) ) New z | Arles nape * Chvemesemne - ’ , , > = 3 —_ 7 » Pp 7 a. > % hy > Jf ~~ > ry vvvwvueugug f gun haw of 4) ) tw Chapracdur J s| 4 Tai estan Posalluliim fu chiemotornis f gener a ir RY KV @® G0 Nen Avorasla pur chre ow aug of 0.0 ole * yy dase of urik cho gr ve, ye law Agteaben® Ya dnclpendesf th RK —— IIMIATATN ANT Anisan wane. mm NANA wewre es -~vveu u va ~wMUUdDGUdDYDOYEYIDOUYYUY Munoel — Gayolen pe Morgen — fal Fy Drie malonate _ 7 7 TMM UB UEU EOD YOUOV EE www ww — Q\0 Fauit ply pari Meena Maly Fete ; - B weeks to err, As -hanolle i [month - Lasily avolable tOsy te Atudy . Singh ming a bag of py Avuual Alimorp his Amerie Mee of linkage yor 3s 4 § 6 F389 4W9 = gems ore pusent om —chnomorowed — in ee Timor Aegpomee — Ans sliakrnn +9 two ayores [ lave >) ~ Mate Mvaloge = [pbs Chomer {nosy ever - JEEVERE-ER £ i a HEE & Id. k wananne Hi . “Bi dutomee mur — > rts —_ - [at ree: yf / l é Neo sbinked untinked unbinedl we OS | fd | Unlinked (uno!) nando New Avra Aogow cha,» op Wrorbmunl . — tr we MENU Yee wee Seige Ik Mate chromosome > Y J—Ahaped , boobed 2 SA Ehromotone 1 fost : Bedy colour 4 tye colour Sreum body =a ed. eye —Dominant charocMie _ "= Weld ‘fe 7 Notwral 1 “ypllos boely 4 + white ey. ~ “Ricass aes ~ MUTANT Body colour § eye colour vane 40% Dred ascii Uru yWyt uta dd bodiod Broun beclind yates, : ale Awd tyeol / fo “hua ne % gtr A eel | y * ai oma eal | (rucbook 5 THATUM Y~ Qretophila , Lye colour a Y= fink ohoraolt. . nevophila yore ahlule 4 colour > pute & m9 ye 1 > ma P/ Ig Ditybrid (10% (Genes Ose urlinke) fount, AABB Xx anbh fomdler AB Oye 1 Fy gin fiabb [45 s } Aobb X Aabb 3 Somat : AB Ab a8 ab > > Fy gun > x? Ae Ab ak ab 2 AACA PRB b Ag : Araby AaB > 3 a a ; Ab [ARB 7) Bhbb, | Post feap ; AoBB AUB ob | V7 | oe | oe [ee | ee mpc Ab Ab \atio = 3 Jeno ue be ARBB | Abb \ 00.88 \ bob 3 | AABb fab Anbb 2 D 4 Prabb 2 ab : wee -- ~~ ee he CUCU HUU YY Test Uenals AaBh aabb Ay, Bb, bb Ra Ske AB Ah Be wb X abel : fab —— frabl> eal aabh, a . # g ©’) ab ab ab ob Ag Prabb feBb | Fab Paks b Ab | fab | fabb [Aste Aube a6 |oaBh | a6 | ooo) asap ob bobb Aobb abr | Qa Sette el vba | Pobb]: Bobp > oalhh: osbb TT 4 y HOY MY gous are Bolinked AB] AG x ab] ab AB, AB ab , ob ABloe Pra| ab [sea GAB, o» AR, Ob ABA , Adlob abjAB , abob AblAa Blam, aol” ie ee qisst|X Not Awe - DTU UY UU GUUS GOD ap ae Polls = 1007, Paroles types enpectid - But obhuswed Adtio = 93% poumlol types. Body Abbour & Lye (olowe ane Highly Hanke RE: ) F ov Af * Wbhu) wh wy yi wild type Your ai a [Link] white yellow Ly — tL wh tte Your vot <=> w we i w ™ wr wt bp ee = 5 eae ’ 2 white gmninidhuns vaitd yPs b : L b 9 — we ~ w w : F OO a yy a > : we mt white miniature 7 wild yet > J > Qe, bo nant repmbl do Pasunkaul “ WA sy tee). (3727) 5 ar ent wt ™ : at ee ; wild type - “Wikiaho. , : a 7 whe , thin’ hae w* 07 +H Wg usild type wo ™ +——+ a yr 0 hd reek Ben Detrminaction 5 a eee 2 O uaa rotsatich - Snsect 5 © By Henking - 1941 st : Horougl spewmalogentsi dscoyoed. 5 X~ body pa 23 chromosomes = mee | at, Auctosones we 2 pit [ty 22, pairs ppain (ost por) 7 both XX oe XY. = femal) Also called. SS Autd-sorms Sdtochnemotemar . = Sn Aumans 83°" ohne aL Orme ks Sent —it / (alaye Chisemorome Bn Drcoraphba 1” pain 1 SUL chemoteme = be RK SB =] Michamisem 4 tone Determination \ ® XX- XY 4. bros0phila , juman beings - fanenks 44 + XX Wu XY umale small: be o j AA + XX An +txy ( Homo mor pric) ’ ( HETEROMORP Hic) 14 Snel Aur Chromeremer : At KR Saar 29tX , aa+y > h avnclie) 4 F > hemegamatis [ategeorctich 2 > > oy FI ima We xy Sxy gat xy [sing YU+XX 4 ps bey eee 5e/, onppeny ane mM -—- ~~ ww wvuvuuuYy 2: AX XO “4. ound , Susoels. , Grasshopper , Cocksoodhue. Parents AA+ XX AA FXO fomale ie G- Arx , AY Arx Aro ¥, AA+AX . AAAXX AA+ xo Anse oY CSE 57, ; wf. Make Auteriog analy fo + 3 * Posen | | Gawmelis IF, SRY Ye ZW- ZZ wy Binds aml Bomb opts Aw “pA + ZW AA ZZ joa. Male AtZ , Atw Artz , AtZ At 22 | AAtzz, AATZW, Alt ZH I ; a 50], maby 5e7. femmad - wae Hayplo ~ biploidy. A mol (32) Lb) Lb, Lo. mugs mites ub uv 9g [16 Apu [16 — Ltheroos trade/16 oh ( dae (32) Arodne toh quis Linked to dur -chiomesenua. arL Called Ae -Lnked gone chavactun Controlled by theme Sere Linked chaxaclias dy Thedn Suhantarne gion Linked Gpharetdaree X — dymeid Atesstve favectpslia vais ris Sartriforae —Blancler's Aare = tppistman Peodh ® piogunic faltan. te grandson Hee. gh dowighkir Diandrie roth to genta. Hough Agr XY g Normale role @® nouns female X Aolourblind forthe Hen — morwol boys y carniea girls \ gamle \ ' yFy ) b/s by > d founits © 3 > geondla > sn XX, xXx > Novmal. Corn 3 3 D 3 ) ) ’ ’ (i 308 dyduiden) poetic: Mandy ey Gu ee Hooug Doggie fatten di gpancon "Xe Aine Qnisiomee ™* te : O x pe xh ( ner on Y) Ona ely one alle produces sft @ pmol A Adleyagous > capzians Cone ality ——t © mala mpee affected © ws a ave Xe ea berets do disease XK a . xr, x mT AY xno x oY . : C C xx, Xx ky wy VUEWU VE UYUr TT —~—— vuw AXY am Drobophile — female XY din sone Wins elder mable urn Brssophla AX > fumale XY - moe XXY > Tnteaswr Mosephile — mlamogaylr_ foonlly — Gavsephlidae Orolr - Diptero. Sin NGble have bun given Avseatoh a Daptophle . ae fintmabian k firthrepeda. p ' Snsecta Cc 1 Diptire 0 : Drerophibidar F : Drosophila G mubanegartin S$ ‘ (Desephi] | XY > oad forma alin xxy [AA | rorrral female XXYY Ap | viermal Aumoke XX AA mprrad female XY Ab o's + Nrmal node Ltinkage Ty Morgoron ptudied son inked germs Arptred Mai, A fale b bain Bt made 3h Ry ile Auiole Aig'fteanthy rom 93:3: | He knew Bat FL - ; - gems as Looted bn X- Chrome CM iene pruent on same chnernos the i ten of frontal gnecombrration, iutre nuuch. Aigher thon te pen. parrital Aiype , 5. ge ae SF guar vedas physical nvsorialion of 2 gents 4 Coineg Lam . p / 6 Jove term p, Lead . + Tight dunked genes — Jaz Recarbival peatly inkud gene > 39-2): ” Yoigon |s dtudlent Alatte vend prepared ponleage Mops « qyr/, gob /. fo _— Dd s ~~ ye YOU UYU BUOY DY OOO www ma A < p. Jw ++ ay aw elton oly b Fi Yous Fo aero vtut He wild Puartat (9aayb y* wt —++—+ a wild ie ao paw = + white vw at a wid Fw yu a +++ d ur yellow while Sj —_ yt wt Ap ee ~~ hd ye yl brown bly Oo” c wis se ou w ST Adbe * ¥ 8 white Reepmbiname ¢ 4.7 | tow “ ‘ ¢ € ‘ ‘ ‘ ‘ P Bw 44 ' ~yeltows: body wha. aye \ t Fy yur ; gt uot > wild d d > Poruntol (98-9) > : + ut > a Care 3 ola 5 je 3 7 “white a > at wt > file : +a ? Fane > : 3 ) oe ) ) ' Sy ¢ orm wt m? ; a ae . naw * tm a € wit, daebpeye wild z wirtodwre wings & e vom a 's ; aft a. & wh mt 7 = = dad sulk, “into ee feeombirank ( = Coney.) 7B em uw? mt wt wy =i = wild oe iatune c wm aa a : = 2 hh Wr mh q beer 4 white S ss Fi i wt omt i -—1— pe as - wild oe a =. 4 vain wom Soe: Ti - om —u ee th vm ai Te rio hd] wom ° all hoe dl yi] mye ~~ ZFRPVVOUOOUUIEUUIPDYOEOSE WITT ~~ aoe Q _ of Ww m whide wt wt +e a + rninielivn _ wil wm 7 bw m Ww ™ see + —>—+ + eee Wild whee 7 minioduag foruntol , Rucombinank \ (6>87,) ; (37.2%, ) wt ww wr om - —— wild >t wirtibuss. w ~ ‘ us Ste hte mt FZ win pore oes , fhite wt mt : wt om a il + iid, +t +p vom ; wom ‘ + PO white rT ae mintafure a wW wn wom graphic. pepasemborbton showry posbion genes on chiomolomys —p Linkage ep. Abwtevank (in)) Ahew dislomee bjw gents “nw prequoney of owing Owed, aeconlinabin ond sh distance bf genes = | Meagan (M ) : 5 8 : po 44 1oet Ly a i f : pee SM Bn shape € becky celoun ye colown wing Avy <3 ——=> —'h- ey ed fecombinalion drug rencss hoe ytd | . pitows Yous boot cvinitye = "Yy Papen “UUVUUUUUOU YY UVyrwe Aickl sll amavmia Not India - ayat ak araf- - Heh He® HB He? Hb* =, Hb? ye’ Be 7 p> + poe’, HEMWS | we HB? pbSyES Noma Ca ‘ Hb a commer. Pramony effect ube => Hb? Qn PB cham oh — A poate Wed aed «=> Nolive [qual Dyfi —> RNA —> brolun / Amino Acid Ti uplaced by A Jovmal 4b (A) Prdosdy a) & i GAG —» Glu. Lowa) i em Ait ull Hb(s) cfAle ioe — 5» 6Uh 7 val. tm RNA) ( wR) woumal 14 Sickle cll amauta (Hb-A) CHb-3°) | Phriobrepy | Llistrepis gene ) Natural dolection Cé deni nantt } Polymorphism TranaVVs (oy) Lethal qe LAenybielonaria (peu tteh Ofvtotomal Aetetsive trait Gy erry dalidones . Aock enyyrne phenylalanine bydiionylase Olrbeim urer gf Mmetaboldim. “ Phinybatamine Lhenylatanere Ayelior ylia Tyrosine Ue ergy 46 absent VUUVUUUdUYUUUYyue~ : Hise june on accumulate ne J dp or mudol 5 gan . Thamsamingse Phamglebamers Tomy g > Phenyl paved yh ela oe hen eon) Phanytala Androyflo 1h 5 Melarums lass Taree Farnrate Rucer 4 1: poe! | ‘ ‘ Ze were ‘ Pedigue Anolysis Le 4 yh: — Baly 04, amensbral nissiory Do wl horigondal Wire - pork O 2 pale vaabial Mine -F ZB @-> Solid, Arot undur eonsiclrakions Pression disease sabia Cakes tt Aeast int bath. pannts helinoyygous iota Now posuak ds olfeelia, athe 1-0 6] OOM Om OH mm ‘ é 4 ( ‘ { XP Re OT / ) + i | xa xy KX lea 3 eat oss er8e poss : fp pdm sah em © kasuyotiype | Gdiogzrorm | Denier Ayrlem. pound mulation. 3 7 TM Hote Snvesun = > chrome Ddwion Sewes Dupli ication gine - Sum dolat Oh OWL ann gus in Aaplrid at 9}, hiss ° =a — \ylwore adult — 2 guvine eae — Nor dn ‘mon - plas Ppitiam én Fi poe docglecy EIDD — daw (Tatomg of 2) Lips (Tiseriy 6] Sex cynomotome) \ ‘ ; : ¢ physical , mend, sutordalion Spo : disorder i Bape on vale oat ee rie + ity Chali with gent as dincicedts tact’ Mandal! pineipbr wt apricotl to human gemilice with fourm ved Nica hans found uty, on on quai hating rehwsitemct, Ynkage, Bex lurked Spd hoonosemall wuddatious Y L . v “euchoal Nununteall ABCDEFGH tome bpbidy DSCOEF dita chowngs. cin ly whole. 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