Pharmaceutical Dosage Forms and Drug Delivery E.

Dissociation constant
System
9. Which of the following excipients are added to tablet
1. The purpose of Phase 3 clinical trial is; formulations to provide enough bulk for compression?
I. Safety A. Glidants D. Disintegrants
II. Effectiveness B. Diluents E. Surfactants
III. Dosage C. Lubricants
A. I, II and III
B. I and III 10. Characteristics of Stevia powder include;
C. II and III I. A natural, non-toxic sweetener
D. I and II II. Contraindicated to phenylketonurics
E. I only III. About 30 times sweeter than sucrose
A. Only 1 D. II and III
2. Which of the following is a correct statement regarding B. I and II E. III only
TDDS? C. I and III
A. Ortho Evra is a testosterone transdermal
system. 11. A hermetic container which permits withdrawal of
B. Skin lotion may be used at the application successive portions of the contents without changing
site of transdermal patches to avoid the strength of the remaining portion
irritation. A. Multiple dose vial
C. Physical exercise and extreme ambient B. Single dose ampule
temperatures (e.g. sauna) may increase the C. Blister package
absorption of drug from Nitroglycerin D. Large plastic bottle for capsule
patch. E. Tamper-evident package
D. Absorption of drug from TDDS is greater
if the patch is applied to a site with a thick 12. Photodegradation can be prevented by packaging drugs
horny layer. in a light resistant container. Which of the following
E. TDDS should be removed when containers is NOT light resistant?
showering, bathing or swimming. A. Colorless bottle covered with aluminum foil
B. Bottle covered with carbon paper
3. Which of the following phrases describe the elixir C. Transparent plastic container
dosage form? D. Amber colored bottle
I. Sweetened and flavored E. Opaque plastic container
II. The product contains alcohol as
preservative 13. This plastic material is rigid and has good clarity thus,
III. Medicated or nonmedicated is used in blister packaging of capsules and tablets is;
A. I only D. I and II A. PET
B. II and III E. I, II and III B. PVC
C. I and III C. PETG
D. APET
4. Which of the following preparations is for external use E. APETG
only?
A. Lugol’s solution 14. Simple syrup can be prepared by;
B. Iodine tincture I. Percolation
C. Magnesium citrate solution II. Solution with heat
D. Belladonna tincture III. Agitation without heat
E. Diphenhydramine elixir A. I, II and III are correct
B. I and II are correct
5. A preparation applied to the skin with a fine camel’s C. II and III are correct
hair brush or glass applicator is known as: D. Only II is correct
A. Glycerite D. Cataplasm E. I and III are correct
B. Liniment E. Glycerogelatin
C. Collodion 15. Features of ophthalmic ointments and gels include;
I. Must be packaged in collapsible ointment
6. For orally administered drug, the dosage form used as tubes having elongated narrow tip
clinical trial material for Phase 1 is; II. Non-sterile preparation
A. Capsule with excipients III. Ointment bases should have a softening
B. Capsule containing active ingredient alone point close to body temperature, both for
C. Tablet without excipient comfort and for drug release
D. Tablet with excipient A. Only I is correct
E. Solution form B. I and III are correct
C. II and III are correct
7. If a drug product requires an antioxidant, which of the D. I and II are correct
following would be used? E. I, II and III are correct

A. Fumed silica 16. Ointment base classified as hydrocarbon base include;

B. Titanium dioxide I. Petrolatum
C. Benzalkonium chloride II. White ointment
D. Butylhydroxyanisole III. PEG ointment
E. Phenylmercuric nitrate A. Only I is correct
B. I and III are correct
8. The following are physicochemical properties to be C. II and III are correct
considered in dosage form design except; D. I and II are correct
A. Physical state E. I, II and III are correct
B. Nature of the illness
C. Polymorphism 17. How many percent of glycerin is contained in
D. Solubility glycerogelatin?
 A. 15% D. 5% C. Solution by chemical reaction
B. 35% E. 10% D. Percolation
C. 40% E. Any of these methods

18. Papers, Moleskin, linen are types of what component 27. All of the following otic preparations are indicated for
of plasters? bacterial infections of the ear EXCEPT;
A. Adhesives A. Auralgan otic Solution
B. Backing material B. Cerumenex Eardrops
C. Absorbents C. Chloromycetin Otic Solution
D. Medicaments D. Corticosporin Otic Solution
E. Container E. Maxitrol Drops

19. Creams ointments may be medicated or nonmedicated. 28. Aromatic Spirit of Ammonia is a reflex stimulant
Which of the following preparations contain a administered;
depigmenting medicament? A. Orally
A. Crotamiton cream B. Topically into the abdomen
B. Tolnaftate cream C. By rubbing into the affected area
C. Hydroquinone cream D. By inhalation
D. Mupirocin ointment E. By subcutaneous injection
E. Tretinoin cream
29. A pharmaceutical solvent water intended for the
20. Type of ointment that must meet sterility test and preparation of aqueous dosage forms except those
requirements for metal particles. intended for parenteral administration is officially
A. Dermatologic ointment known as;
B. Ophthalmic ointment A. Water, USP
C. Rectal ointment B. Purified Water, USP
D. Nasal ointment C. Water for Injection, USP
E. Vaginal ointment D. Sterile Water for Injection, USP
E. Bacteriostatic Water for Injection, USP
21. An enema used for the diagnostic visualization of the
GIT is; 30. A topical solution employed as astringent was or wet
A. Starch enema dressing is;
B. Barium sulfate enema A. Aluminum Subacetate Topical Solution
C. Aminophylline enema B. Povidone-Iodine Solution
D. Nutritive enema C. Coal Tar Topical Solution
E. Hydrocortisone enema D. Hydrogen Peroxide Solution
E. Chlorhexidine Topical Solution
22. Nasal preparations are employed;
I. As nasal decongestant for prevention and 31. Pharmaceutical solutions are of different
treatment of allergic rhinitis characteristics, uses and methods of preparation.
II. To restore moisture and relieve dry, Which of the following statements correctly describe a
congested and inflamed nasal membranes specific solution?
III. In the form of nose drops or sprays A. Magnesium citrate solution is prepared by
A. I, II and III simple solution method
B. I and II B. Liniments are ethereal solutions
C. II and III C. Embrocations are used externally and are
D. I and III applied with rubbing
E. I only D. Bactidol® is a collyrium
E. Douches are rectal injections
23. Flexible collodion,USP, is rendered waterproof by the
addition of; 32. An aqueous solution used for irrigative cleansing of the
A. Menthol D. Camphor vagina is termed as;
B. Castor oil E. Alcohol A. Enema D. Douche
C. Ether B. Lavatio ori E. Collunarium
C. Embrocation
24. Which of the following statements is correct?
A. Diapid nasal spray is used for the prevention 33. Characteristics of large volume parenterals include all
and treatment of perennial allergic rhinitis of the following EXCEPT;
B. Lugol’s solution contains sodium iodide as co- A. Sterile
solute B. Isotonic
C. Simple syrup can be prepared by percolation C. Package in containers not exceeding 1 liter
D. Calcium hydroxide Topical Solution is also D. Meet standards for particulate matter
known as Liquor Carbonis Detergens E. Colored
E. Magnesium citrate solution is used as
antidiarrheal 34. The method of sterilization employed for heat-labile
enzyme preparations, catheters, needles and plastic
25. This tincture is a topical protectant. disposable syringes is;
A. Belladonna tincture A. Sterilization by ionizing radiation
B. Compound benzoin tincture B. Gas sterilization
C. Tolu balsam tincture C. Autoclaving
D. Sweet orange peel tincture D. Steam sterilization
E. Iodine tincture E. Dry heat sterilization

26. Which method is used in the preparation of Ipecac 35. Parenteral preparations are of different types. Which of
Syrup? the following is a dry Solid for Injection?
A. Solution with the aid of heat A. Propofol, USP
B. Solution by agitation without the aid of heat
 B. Imipenem and Cilastatin for Injectable A. Estring
Suspension, USP B. Interferon
C. Methylprednisolone Acetate Suspension, USP C. Human Growth Factor
D. Insulin Injection, USP D. Rituximab
E. Cefuroxime for Injection, USP E. Epoeitin alfa

36. Pastes are semi-solid preparations that generally 44. Advair diskus is a novel preparation for;
contain a larger proportion of solid materials so are; A. Oral inhalation
I. Less greasy and stiffer than ointments B. Parenteral administration
II. More macerating and more C. Subgingival application
penetrating than ointments D. Vaginal insert
III. Are effectively employed to absorb E. Topical delivery
serous secretions
A. I and II D. III only 45. Characteristic of drug substance best suited for
B. II and III E. I, II and III incorporation into an extended release product include;
C. I and III I. Uniformly absorbed form the GIT
II. Possess a good margin of safety
37. Considerations in the use of TDDS include; III. Used in the treatment of acute rather than
I. Rotating locations within the chronic conditions
recommended site should be avoided in A. Only I is correct
the application of replacement patches B. I and III are correct
II. TDDS should be removed when C. I and II are correct
showering, bathing or swimming D. I, II and III are correct
III. Use of the skin lotions should be avoided E. Only I is correct
at the application site because they affect
skin hydration and can also alter the 46. Camphor is usually comminuted by which of the
partition coefficient between the drug in following techniques?
the TDDS and the skin A. Trituration
A. I, II and III D. II and III B. Levigation
B. I and II E. III only C. Sieving
C. I and III D. Pulverization by intervention
E. Micronization
38. All of the following statements are true regarding
biologics, EXCEPT; 47. The vehicle of Effervescent granulated salts usually
A. Biologic products must pass control contain;
requirements such as potency, sterility, I. Citric acid
pyrogens and constituent materials. II. Tartaric acid
B. Freezing is required in the storage of III. Sodium bicarbonate
biologics. A. I, II and III
C. Most biologics have an expiration date of a B. I and III
year or longer after the date of manufacture. C. II and III
D. Biologics are generally administered by D. Only II is correct
injection E. I and II
E. Toxoids and Vaccines are biologics for active
immunity 48. Pharmaceutics is concerned with the following areas of
pharmaceutical dosage form design EXCEPT;
39. Which of the following biologics is available in oral A. Formulation
form as enteric coated capsules? B. Manufacture
A. Typhoid vaccines C. Stability
B. Hepatitis B vaccine D. Sales and marketing
C. Diphtheria and Tetanus Toxoids E. Effectiveness
D. Measles Virus Vaccine
E. Hepatitis Vaccine 49. Drug substance can be protected from the destructive
influences of atmospheric oxygen or humidity through;
40. Methylcellulose is used in ophthalmic solutions as; I. Coated tablets
A. Buffer D. Thickener II. Enteric coated tablets
B. Preservative E. Isotonic agent III. Sealed ampoules
C. Sterilizing agent A. I, II and III D. I and III
B. I and II E. III only
41. Which of the following preparations is NOT sterile? C. II and III
A. Eye drop
B. Implant 50. Preformulation considerations include all of the
C. Suppository following EXCEPT;
D. Solution for Injection A. Polymorphism
E. Dialysis Solution B. Stability in the presence of expected excipients
C. Membrane permeability
42. A novel drug delivery system Cyanocobalamine D. Particle size
(Nascobal Gel) used in the treatment of vitamin B12 E. Dissolution
deficiency is available as;
A. A controlled release sublingual application 51. Liquid drugs such as Vit A, D and E are formulated as;
B. Microspheres for injection A. Sublingual tablet
C. A nasal gel B. Soft gelatin capsule
D. Automatic injector C. Nasal inhaler
E. Chewable dispersible tablet D. Compressed tablets
E. Hard gelatin capsule
43. Products of biotechnology include all of the following
EXCEPT;
52. The original appearance, palatability, uniformity, C. Leaching
dissolution and suspendability are retained. The type of D. Deformation upon storage
stability described is; E. Sorption
A. Physical
B. Chemical 60. The following drug products require colorants
C. Toxicologic EXCEPT;
D. Microbiologic A. Capsules
E. Therapeutic B. Compressed tablets
C. Sugar-coated tablets
53. Approaches in the stabilization of drug products D. Suppositories
against hydrolytic decomposition include all of the E. Suspension
following EXCEPT;
A. Replacement of atmospheric oxygen present in 61. Two plasticized gelatin ribbons are continuously and
container with an inert gas such as nitrogen simultaneously fed with liquid or paste fill between the
B. Supply drug in a dry form for reconstitution rollers of the rotary die mechanism. What method of
C. Refrigeration preparing SGC is described?
D. Use of buffering agents A. Plate process
E. Suspending the drug in non-aqueous vehicle B. Rotary die process
rather than dissolving them in an aqueous C. Reciprocating die process
medium D. Punch method
E. Both B and C
54. Based on USP guidelines for extemporaneously
prepared drug products, the stability of water 62. A tablet excipient that causes adhesion of powder
containing formulation prepared from ingredients in particles in tablet granulation
solid form is; A. Lubricant D. Diluent
A. Not later than 25% of the time remaining until B. Disintegrant E. Antiadherents
the products expiration date or 6 months C. Binder
whichever is earlier.
B. A beyond use date of 6 months 63. An excipient used in sugar free-chewable tablet
C. A beyond use date not later 14 days on storage A. Mannitol D. Lactose
at cold temperature B. Sorbitol E. Crystalline maltose
D. A beyond use date of the intended duration of C. Xylitol
therapy or 30 days whichever is earlier
E. None of these 64. In preparing vaginal inserts, the following excipients
are used EXCEPT;
55. TRUE statements regarding flavoring of A. Lubricant
pharmaceuticals include all of the following EXCEPT; B. Disintegrating agent
A. Fruit or citrus flavors combat acid or sour taste C. Filter
of drugs D. Coating agent
B. Children prefer less sweet with tart rather than E. Dispersing agent
a fruit flavor pharmaceutical
C. Organic esters, alcohols and aldehydes are 65. Wecobee bases used in suppositories are triglycerides
pleasant to taste derived from;
D. Chewable tablets and lozenges are usually A. Mineral oil
flavored and sweetened B. Coconut oil
E. In selecting a flavorant, the age of the intended C. Almond oil
patient must be considered D. Olive oil
E. Theobroma oil
56. The following products require the addition of
preservatives EXCEPT; 66. In preparing suppositories by molding from a melt,
A. Syrups lubricating the mold is required if the suppository is;
B. Emulsions A. PEG-based
C. Semisolid preparations B. Cocoa butter-based
D. Ophthalmic products C. Glycerinated gelatin based
E. Large volume parenterals D. Both B and C
E. All of these
57. Strip packs, blister packs, tape seals and bubble packs
are examples of; 67. Suppositories using this base should be moistened first
A. Light-resistant packaging with water to avoid irritation to the tissue upon
B. Compliance packaging insertion;
C. Child-resistant packaging A. Cocoa-butter
D. Tamper-resistant packaging B. Glycerinated gelatin
E. Adult-senior use packaging C. Wecobee base
D. Glyceryl monopalmitate
58. Characteristics of APET and PETG plastic materials E. Witepsol base
include;
I. Transparent 68. TRUE statement about PEG-based suppositories
II. Unsuitable for gamma radiation include;
III. Has excellent luster I. Stored at room temperature
A. I, II and III D. I and III II. Leaks from the orifice
B. I and II E. III only III. It dissolves in the body fluid to release the
C. II and III active drug
A. I, II and III
59. Problems encountered with plastic containers include B. I and III
all of the following EXCEPT; C. II and III
A. Permeability D. I and II
B. Alkalinity E. I only
 77. The following are oral suspensions EXCEPT;
69. Tablets may differ in terms of release mechanism. A. Maalox suspension
Which of these tablets has delayed-release feature? B. Combantrin suspension
A. Sugar-coated tablets C. Mesalamine suspension
B. Film-coated tablets D. Amoxicillin suspension
C. Chewable tablets E. Gaviscon Liquid suspension
D. Enteric coated tablets
E. Instant dissolving/disintegrating tablet 78. Which of the following properties is undesirable in
pharmaceutical suspension?
70. Reasons for suspension include; A. Thixotropy
I. Sustaining effect B. Caking
II. Taste C. Cracking
III. Stability D. Bleeding
A. I, II and III E. Flocculation
B. II and III
C. I and II 79. Single phase gels;
D. III only I. Are made up of small inorganic particles
E. I and III II. Exhibit thixotropy
III. Are those in which no apparent
71. Characteristics of particles of suspension in ideal boundaries exist between the dispersed
situation include; phase and the dispersion medium
I. Perfectly spherical in dilute suspension A. I and III
II. No collision of particles B. II and III
III. Settling of particles obey Stokes’ Law C. I and II
A. I, II and III D. III only
B. II and III E. I, II and III
C. I and II
D. III only 80. Aluminum hydroxide gel is;
E. I and III I. Prepared by chemical reaction method
II. An antacid
72. A technique of reducing particle size producing 10- III. Applied externally
50um particle diameter is; A. I and II
A. Dry milling B. II and III
B. Micropulverization C. I and II
C. Micronization D. III only
D. Spray drying E. I, II and III
E. Fluid energy grinding
81. The first step in the continental method of preparing
73. Bentonite, a suspending agent is classified as; emulsion is the combination of;
A. Clay A. Gum and water
B. Plant colloid B. Gum and oil
C. Synthetic C. Oil and water
D. Cellulose D. Gum and active ingredient
E. Protein substance E. Gum, water and oil are mixed all together

74. Caking of particles in suspension can be prevented by 82. Surfactants of HLB value 3 to 6 are employed as;
inducing flocculation. Which of the following can be A. O/W emulsifier
employed as flocculating agent? B. W/O emulsifier
I. Diluted bentonite magma C. Antifoaming agents
II. Surface active agent D. Wetting agents
III. Electrolytes E. Solubilizing agents
A. I, II and III
B. II and III 83. This theory of emulsification assumes monomolecular
C. I and II layers of emulsifying agent curved around a droplet of
D. I and III the internal phase.
E. III only A. Surface tension theory
B. Plastic-film theory
75. These substances increase the viscosity of the C. Oriented-wedge theory
dispersion medium. D. Interfacial film theory
A. Wetting agents E. Molecular layer theory
B. Flocculating agents
C. Suspending agents 84. Creaming of emulsion, though reversible, is not
D. Solubilizing agents esthetically acceptable. This problem can be remedied
E. All of these by increasing the viscosity of the external phase.
Which of the following can promote the desired
76. TRUE statements regarding packaging, labeling and condition?
storage of suspensions include; A. Agitation
I. Packaged in an oversized container to B. Reformulation
facilitate thorough mixing C. Addition of suspending agents
II. A “shake well” label must be affixed D. Addition of preservatives
III. Must be protected from freezing E. Addition of thickeners
A. I, II and III
B. II and III 85. The separation of internal phase from the emulsion is
C. I and III called;
D. I and II A. Aggregation D. Flocculation
E. III only B. Creaming E. Sedimentation
C. Breaking
 D. Pathologic state
86. Microemulsions are; E. Tolerance
I. Thermodynamically stable system
II. Optically transparent 95. The copies of the NDA submitted by the applicant
III. O/W system stabilized by surfactant include;
A. I, II and III I. Field copy
B. II and III II. Pre-approval copy
C. I and II III. Archival copy
D. I and III A. I, II and III
E. only I B. II and III
C. I and II
87. Inhalation aerosols are commonly employed; D. I and III
A. As anti-infective E. III only
B. As contraceptives
C. In anorectal conditions 96. Clinical trial materials include;
D. In asthma therapy I. The proposed new drug
E. As local anesthetic II. Placebos
III. Comparator drug
88. In mixing powder, the diluent is added in portions to A. I only
the potent drug, with trituration after each addition. B. I and III
What principle is described? C. II and III
A. Levigation technique D. I and III
B. Geometric dilution E. I, II and III
C. Pulverization with intervention
D. Comminution 97. A chemical compound that has a fundamental desired
E. Spatulation biologic or pharmacologic activity is referred to as;
A. Prodrug
89. Powders containing deliquescent and hygroscopic B. Lead compound
materials should be wrapped in what kind of paper? C. Goal drug
I. Vegetable parchment D. All of these
II. Glassine paper E. None of these
III. Waxed paper
A. I only 98. These are solid dosage forms which are designed to be
B. III only inserted under the skin by special injectors or by
C. I and II surgical incision.
D. II and III A. Pellets
E. I, II and III B. Inserts
C. Plasters
90. In dry or fusion method of preparing effervescent D. Pills
granulated salt, the binding agent used is; E. Troches
A. Alcohol-water mixture
B. Water of crystallization of citric acid 99. Cocoa butter, NF is also known as;
C. Alcohol, 95% A. Yellow wax D. Spermaceti
D. Lanolin B. Paraffin E. Lanolin
E. Acacia mucilage C. Theobroma oil

91. A tablet which is 50% larger and heavier than the 100. One of the following is NOT used in the
original uncoated one is; preparation of oral solutions, syrups and elixirs.
A. Sugar-coated tablet A. Ethylene glycol
B. Film-coated tablet B. Alcohol, USP
C. Enteric-coated tablet C. Propylene glycol
D. Chocolate coated tablet D. Purified water, USP
E. Gelatin coated tablet E. Glycerin, USP

92. Solid dosage administered by oral route include; 101. Salicylic acid collodion contains how many
I. Hypodermic tablets percent of salicylic acid in Flexible Collodion, USP?
II. Troches A. 5% D. 15%
III. Lollipops B. 3% E. 1%
A. Only I is correct C. 10%
B. II and III are correct
C. I and II are correct 102. Compared with syrups, elixirs are;
D. I, II and III are correct I. Less sweet
E. I and III are correct II. Less effective in masking the taste of
medicinal substances
93. Amount administered to a patient after exposure or III. More viscous
contraction of the illness A. I, II and III D. II only
A. Prophylactic dose B. II and III E. I only
B. Therapeutic dose C. I and II
C. Priming dose
D. Maintenance dose 103. TRUE statements concerning bulk powders;
E. Minimum effective concentration I. Oral powders are mixed with water or
other beverages before swallowing
94. Factors considered in determining a drug’s dose during II. Douche powders are dissolve in warm
clinical trial include all of the following EXCEPT; water for vaginal use
A. Age III. Dusting powders include topical anti-
B. Body weight infective, antifungal and antiperspirant
C. Appearance and taste A. I, II and III are correct
 B. I and III are correct E. Not an injectable product
C. II and III are correct
D. Only II is correct 112. All of the following are used as vehicle in various
E. I and II are correct dosage forms EXCEPT;
A. Syrup, USP
104. Blending of powders may be accomplished by; B. Peanut oil
I. Spatulation C. Anise oil
II. Sifting D. Bacteriostatic water for injection
III. Levigation E. White petrolatum
A. I, II and III D. I and II
B. I and III E. III only 113. TRUE statement regarding tartrazine include;
C. II and III I. An FD&C color additive
II. Can cause hypersensitivity reactions in some
105. Different technologies are employed in preparing individuals
modified release products. Glucotrol XL, Procardia XL III. Imparts red color to the preparation
and Covera HS are examples of; A. I only D. II and III
A. Coated beads/granules B. II only E. I, II and III
B. Microencapsulation C. I and II
C. Matrix tablet
D. Osmotic tablet 114. Type II glass container is;
E. Hydrocolloid system I. Highly resistant borosilicate
II. Can be used as container for parenterals
106. F, D and C lakes are used to color; III. Treated soda-lime glass
I. Sugar coated tablets A. I and III
II. Pharmaceutical suspension B. II and III
III. Syrups C. I only
A. III only D. I and III D. I and II
B. II and III E. I, II and III E. I, II and III
C. I and II
115. A sugar-based lozenge on a stick (lollipop) used in
107. Advantages of film-coating over sugar-coating controlling breakthrough pain in cancer patients is;
include; A. Fentanyl Actiq
I. More durable B. Dormicum
II. Less bulky C. Dequadin
III. Less time consuming to apply D. Difflam
A. I, II and III are correct E. Alaxan-FR
B. I and III are correct
C. II and III are correct 116. Spansule capsule is;
D. Only I is correct I. An example of extended release product
E. Only III is correct prepared by embedding drug in a slowly
eroding hydrophilic matrix system
108. Characteristic of added substances to capsule II. A capsule containing beads of different
formulation; coating thickness
I. Harmless in quantities used III. A half-colored, half-transparent hard
II. Do not interfere with requisite compendial gelatin capsule containing colored beads
assays and tests or granules
III. Do not impair product’s bioavailability, A. Only III is correct
therapeutic efficacy or safety B. I and III are correct
A. I, II and III are correct C. II and III are correct
B. I and III are correct D. I and II are correct
C. II and III are correct E. I, II and III are correct
D. Only I is correct
E. I and II are correct 117. The transdermal patch used in travel-related
nausea and vomiting that is to be worn in a hairless
109. TRUE statements about the function of excipients area behind the ear is;
used in tablet formulation EXCEPT; A. Transdermal Nicotine
A. Binders promote granulation B. Transdermal Clonidine
B. Glidants promote the flow of the tablet C. Transdermal Testosterone
granulation D. Transdermal Nitroglycerin
C. Lubricants help the patient to swallow the tablet E. Transdermal Scopolamine
D. Diluents make up the desired bulk of the tablet
formulation 118. A part of a monolithic transdermal system that
E. Disintegrants promote the breakup of tablets after functions to store and release the drug at the skin-site is
administration the;
A. Occlusive backing layer
110. The vehicle used in Calamine Lotion is; B. Liquid drug reservoir
A. Aluminum acetate solution C. Semi permeable membrane
B. Lead acetate solution D. Matrix system
C. Calcium hydroxide solution E. Adhesive layer
D. Magnesium hydroxide solution
E. Purified water, USP 119. TRUE statement about vanishing cream include;
I. A W/O type of cream
111. Propofol, USP is a/an; II. Also known as Petrolatum Rose Water
A. Solution for injection Ointment
B. Dry solid for injection III. Contains large amount of water that
C. Injectable emulsion evaporates after application leaving a thin
D. Injectable suspension film of stearic acid
 A. I, II and III D. I and III III. Containing ingredients dispersible in
B. II and III E. III only water
C. I and II A. I and II
B. II and III
120. Fleet enema is an example of; C. I, II and III
A. Diagnostic enema D. I and III
B. Nutritive enema E. I only
C. Evacuation enema
D. Non medicated enema 130. Upward creaming takes place in unstable
E. Hydrocortisone enema emulsions in which the internal phase has a _____
density than the external phase.
121. Which of the following phrases describe the elixir A. Lesser
dosage form? B. Greater
I. A Colloidal dispersion C. Equal
II. Alcohol and water are its primary solvents D. Minimal
III. The product is self-preserving due to high E. Exceedingly high
alcohol content
A. II only 131. Which of the following can exhibit a reversible
B. II and III sol-to-gel or gel-to-sol transformation?
C. I and III A. Gels
D. I and II B. Magmas
E. I, II and III C. Lotions
D. Mixture
122. A colorless to slightly yellow, clear, effervescent E. Both A and B
liquid having a sweet, acidulous taste and a lemon
flavor; 132. Membrane-controlled transdermal system contains
A. Citric acid syrup the following layers;
B. Magnesium citrate Solution I. An occlusive backing layer
C. Simple syrup II. Drug matrix system
D. Calcium hydroxide solution III. Microporous rate-limiting membrane
E. Aluminum acetate solution A. Only III is correct
B. I and III are correct
123. Magnesium aluminum silicate is also known as; C. II and III are correct
A. Kaolin D. Bentonite D. I and II are correct
B. Acacia E. Tragacanth E. I, II and III are correct
C. Veegum
133. Method used to achieve controlled release from
124. Several processes affect the stability and solid dosage form
pharmaceutical elegance of dispersions. Reversible I. Coated beads and granules
process include; II. Complex formation
I. Caking III. Ion-exchange resin
II. Creaming A. I, II and III are correct
III. Breaking B. I and III are correct
A. I, II and III D. II and III C. I and II are correct
B. I and II E. II only D. II and III are correct
C. I and III E. Only I is correct

125. The delivery of fluoride to the teeth may be 134. Components of glycerogelatin EXCEPT:
accomplish through; A. Gelatin
A. Sonophoresis D. Ultrasound B. Petrolatum
B. Phonophoresis E. All of these C. Medicinal agent
C. Iontophoresis D. Glycerin
E. Water
126. The drug antidote for radiation exposure is;
A. Cs D. Prussian blue 135. Drug dosage form/s that is/are protected from the
B. Acetazolamide E. Gallium destructive influence of atmospheric oxygen or
C. Captopril humidity.
A. Coated tablets D. Both A and B
127. A radiopharmaceutical used diagnostically to B. Sealed ampules E. Both A and C
evaluate thyroid fraction and morphology. C. Enteric coated
A. Samarium-153
B. Sodium Iodide-123 136. Drug dosage form that are protected from the
C. Holmium-166 destructive influence of gastric acid after oral
D. D. Cobalt-57 administration.
E. Stronium-89 Chloride A. Enteric coated tablets
B. Coated tablets
128. This nonradioactive drug is used as an alternative C. Sealed ampoules
to a treadmill stress test prior to cardiac imaging. D. Flavored syrups
A. Dipyridamole (Persantine) E. Suspension
B. Cimetidine (Tagamet)
C. Captopril (Capoten) 137. The amount of heat absorbed when 1 g of a liquid
D. Furosemide (Lasix) vaporizes is known as the heat of vaporization of that
E. Acetazolamide (Diamox) liquid and is measured in _______.
A. Celsius
129. Inorganic hydrogels; B. Calories
I. Single Phase System C. Grams
II. Bentonite Magma D. Liter
 E. Atmosphere drug product and becomes available at the site of
action.
138. Use to promote and maintain dispersion of finely A. Drug’s solubility
subdivided particles of liquid in a vehicle in which it is B. Adsorption
immiscible. C. Peak concentration
A. Emulsifying agent D. Bioavailability
B. Levigating agent E. Serum concentration time
C. Plasticizer
D. Solvent 148. Drug products that contain the identical therapeutic
E. Humectant moiety or its precursor but not necessarily in the same
amount or dosage form as the same salt or ester.
139. Used as a filtering aid for its adsorbent qualities. A. Pharmaceutical alternatives
A. Emulsifying agent B. Pharmaceutical equivalents
B. Humectants C. Bioequivalence drug product
C. Levigating agent D. Therapeutic equivalent
D. Solvent E. Bioavailability
E. Clarifying agent
149. Drug products that contain identical amounts of
140. Used to prevent drying or preparations, the identical active drug ingredients, that is, the same
particularly ointments and creams. salt or ester of the same therapeutic moiety, in identical
A. Levigating agents D. Humectant dosage forms but not necessarily containing the same
B. Plasticizer E. Solvent inactive ingredients.
C. Ointment base A. Pharmaceutical alternatives
B. Pharmaceutical equivalents
141. Liquid used as an intervening agent to reduce the C. Bioequivalent drug product
particle size of a powder by grinding, usually in a D. Therapeutic equivalents
mortar. E. Bioequivalence
A. Plasticizer
B. Emulsifying agent 150. Drug substance physiochemical properties that
C. Solvent influence bioavailability of oral drugs.
D. Levigating agent A. Particle size D. Liquid solubility
E. Chelating agent B. Salt form E. All of the above
C. Hydration
142. Used to impart color to liquid and solid
preparations. 151. Pharmaceutical ingredients that influence
A. Flavorant bioavailability of oral drugs.
B. Colorant A. Fillers D. Lubricants
C. Clarifying agent B. Binders E. All of the above
D. Solvent C. Coatings
E. Humectant
152. Characteristics of dosage forms that influence the
143. Used in tablet and capsule formulations to improve bioavailability of oral drugs.
flow properties of the powder mixture. A. Disintegration rate D. Storage condition
A. Tablet lubricant B. Dissolution rate E. All of the above
B. Tablet glidant C. Product age
C. Tablet disintegrant
D. Tablet opaquant 153. Physiologic factors that influence the bioavailability of
E. Tablet polishing agent oral drugs.
A. Gastric emptying time
144. Used in tablet formulations to reduce friction B. Intestinal transit time
during tablet compression. C. Gastrointestinal abnormality
A. Tablet lubricant D. Pathologic condition
B. Tablet glidant E. All of the above
C. Tablet disintegrant
D. Tablet opaquant 154. Site of sublingual route of administration
E. Tablet polishing agent A. Rectal D. Under the tongue
B. Heart E. Spine
145. Which of the following given is consider as C. Bone
example of a tonicity agent?
A. Sodium chloride 155. A coronary vasodilator used in the prophylaxis and
B. Mineral oil treatment of angina pectoris, which dissolve under the
C. Sodium glycolate tongue.
D. Liquid glucose A. Aspirin D. Phenytoin
E. Hydroxyl cellulose B. Aspilet E. Warfarin
C. Nitroglycerin
146. It describes the passage of (drug) molecule through
a membrane that does not actively participate in the 156. Which statement is not true for rectal route of
process. administration?
A. Drug absorption A. Used for local effect
B. Transport mechanism B. Used for systemic effect
C. Passive diffusion C. Preferred for drugs that are destroyed or
D. Osmosis inactivated by the environments of the stomach
E. Dissociation and intestines.
D. 100% of drug absorbed bypass the liver
147. The rate and extent to which an active drug E. Inconvenient
ingredient or therapeutic moiety is absorbed from a
157. Which statement is not true in parental route of drug 169. Preservative used for soft gelatin capsules
administration? A. Glycerin D. 80% ethyl alcohol
A. Rapid absorption B. Sorbitol E. 95% ethyl alcohol
B. Little is lost C. Methylparaben
C. For uncooperative unconscious patients
D. Once injected, withdrawal of drug is easy 170. Compressed tablets coated with a thin layer of a
E. Sterile polymer capable of forming a skin like film.
A. Sugar coated D. Enteric coated
158. Semisolid that has greater aesthetic appeal for their B. Film coated E. Buccal tablet
non greasy character, ability to vanish into the skin upon C. Gelatin coated
rubbing and ability to absorb serous discharges from the
skin lesions. 171. Tablet which has a smooth rapid disintegration when
A. Pastes D. Powder chewed or allowed to dissolved in the mouth has a creamy
B. Lotions E. Ointment base, usually of specially flavored and colored mannitol.
C. Creams A. Sugar coated tablet
B. Enteric coated tablet
159. Semisolid that contain more solid materials, stiffer and C. Buccal tablet
less penetrating, preferred when protective action is D. Chewable tablet
desired. E. Sublingual tablet
A. Ointment D. Suspension
B. Pastes E. Lotion 172. Prepared by compressing granular effervescent salts
C. Creams that release gas when in contact with water.
A. Molded tablet D. Effervescent tablet
160. Dosage form of choice if increased spreadability over B. Tablet triturates E. Dispensing tablet
large areas of skin is desired. C. Hypodermic tablet
A. Cream D. Pastes
B. Ointment E. Powder 173. Used to determine the tablet’s durability
C. Lotion A. Hardness tester
B. Friability
161. Characteristics of ophthalmic preparations, EXCEPT C. Disintegration testing apparatus
A. Sterile D. Microprocessor
B. Free of grit E. Tablet dissolution
C. Usually absorbed in great extent
D. Solution, ointment and suspension form may be 174. Described dosage forms having drug release features
employed based on time, course and/or location that are designed to
E. None of the above accomplish therapeutic or convenience objectives not
offered conventional or immediate release form.
162. Site of excretion of volatile drugs A. Extended release
A. Kidney D. Saliva B. Modified release
B. Sweat glands E. Lacrymal fluids C. Delayed release
C. Lungs D. Repeat action
E. Targeted release
163. Example of drug that enter breast milk and may be
passed on to nursing infants EXCEPT 175. Dosage forms that allows a reduction in dosing
A. Theophylline D. Diltiazem frequency from that necessitated by a conventional dosage
B. Reserpine E. None of the above form, such as solution or an immediate release dosage
C. Barbiturates form.
A. Modified release D. Repeat action
164. Method for the determination of particle size B. Extended releaseE. Targeted release
A. Sieving D. Light scattering C. Delayed release
B. Microscopy E. All of the above
C. Sedimentation rate 176. Dosage form designed to release the drug at a time
other than promptly after administration
165. Solid dosage forms in which medicinal agents and/or A. Modified release D. Repeat action
inert substances are enclosed in a small shell of gelatin. B. Extended releaseE. Targeted release
A. Capsules D. Suppositories C. Delayed release
B. Tablets E. Coated tablet
C. Pills 177. Drug release directed toward isolating or
concentrating a drug in a body region, tissue, or site of
166. It is obtained by the partial hydrolysis of collagen absorption or for drug action.
obtained from the skin, white connective tissue, and bones A. Modified release D. Targeted release
of animals. B. Extended releaseE. Repeat action
A. Agar D. Albumin C. Delayed release
B. Gelatin E. Dye
C. Talc 178. Absorption bases obtained from the wool of sheep, is a
purified waxlike substance that has been cleaned,
167. Capsule sizes available for human use deodorize, and decolorized.
A. 00 D. 3 A. Petrolatum D. Yellow ointment
B. 1 E. All of the above B. Lanolin E. None of the above
C. 2 C. White ointment

168. Temperatures that thermally bond the capsules’ cap 179. Package for ointments and other semisolid
and body. preparations.
A. 15°C-20°C D. 30°C-35°C A. Large mouth jars
B. 20°C-25°C E. 40°C-45°C B. Metal tubes
C. 25°C-30°C C. Plastic tubes
D. Well closed container
 E. All of the above A. Clindamycin phosphate
B. Clotrimazole
180. Plastic masses containing gelatin (15%), glycerin C. Miconazole nitrate
(40%), water (35%) and medical substance (10%). D. Nonoxynol-9
A. Gels D. Glycerogelatins E. Bisacodyl
B. Pastes E. Gelatins
C. Plasters 191. Example of vaginal suppositories
A. Bisacodyl D. Hydromorphone
181. The ideal molecular weight of a drug for transdermal B. Chlorpromazine E. Clotrimazole
drug delivery is C. Hydrocortisone
A. 1000 and below D. 400 and below
B. 800 and below E. None of the above 192. A viscous liquid, miscible with water and alcohol,
C. 600 and below frequently substituted for glycerin in modern
pharmaceutical formulations.
182. Advantages of transdermal drug delivery systems A. Isopropyl alcohol D. Glycerol
EXCEPT B. Purified water E. Tap water
A. It can avoid gastrointestinal drug absorption C. Propylene glycol
difficulties
B. It avoid first pass effect 193. Purified water, USP, is obtained by the following
C. They are noninvasive EXCEPT
D. Only potent drugs are suitable candidates for A. Distillation
transdermal delivery B. Ion exchange treatment
E. They are easily and rapidly identified in C. Reverse osmosis
emergencies D. All of the above
E. None of the above
183. The first transdermal system for hypertension
A. Nicotine D. Estradiol 194. Processes referred to in the industry as cross-flow
B. Clonidine E. Nifedipine membrane filtration.
C. Nitroglycerin A. Ion exchange method
B. Reverse osmosis
184. General guidelines for TDDS’s EXCEPT C. Cation exchange
A. It should be apply to clean, dry skin D. Anion exchange
B. Udr og skin lotion should be avoided at the E. Distillation method
application site
C. It can be physically altered by cutting 195. Methods of expressing the strengths of pharmaceutical
D. It may be left on when showering, bathing, or preparations EXCEPT
swimming A. %w/v
E. It should be applied with thoroughly clean hands B. %w/w
C. %w/w
185. Suppositories that are shaped like a bullet, or torpedo D. Ratio strength
or the little finger E. Ratio strength
A. Rectal
B. Vaginal 196. A normal physiologic body response to rid itself of a
C. Urethral noxious or toxic substance, such as rotavirus or Escherichia
D. Nasal coli.
E. Aural A. Diarrhea
B. Vomiting
186. Suppositories that are usually globular, oviform, or C. Acidosis
cone-shaped and weigh about 5g when cocoa butter is the D. Hypovolemic shock
base. E. Fever
A. Rectal D. Nasal
B. Vaginal E. Aural 197. Concentrated aqueous preparations of a sugar or sugar
C. Urethral substitute with or without flavoring agents and medicinal
substances.
187. Solid dosage forms intended for insertion into the A. Syrups D. Magma
body orifices where they melt, soften or dissolve and exert B. Elixir E. Juice
local or systemic effects. C. Solutions
A. Suppositories D. Emulsion
B. Tablets E. Lozenges 198. Clear, sweetened hydroalcoholic solutions intended
C. Pills for oral use and are usually flavored to enhance their
palatability.
188. The most frequently employed suppository bases. A. Syrups
A. Water miscible bases B. Elixir
B. Polyethylene glycols C. Solutions
C. Fatty bases D. Juice
D. Glycerin E. Magma
E. Polyoxyl 40 stearate
199. Self preserving elixir and do not require the addition
189. Type of suppositories that is thinner and tapered, often of an antimicrobial agent.
about 5mm in diameter. A. 2%-4% alcohol
A. Rectal B. 4%-6% alcohol
B. Urethral C. 6%-8% alcohol
C. Vaginal D. 8%-10% alcohol
D. Nasal E. 10%-12% alcohol
E. Aural
200. Alcoholic or hydroalcoholic solutions prepared from
190. Example of rectal suppositories vegetable materials or from chemical substances.
 A. Elixir D. Solution 211. Reason/s for preparing suspensions EXCEPT
B. Syrup E. Juice A. Drugs are chemically unstable in solution
C. Tinctures B. Ease of swallowing
C. Used to prepare a palatable liquid dosage form
201. Water-soluble organic mercurial antibacterial agent D. Flexible in administration of a range of doses
used topically for its bacteriostatic and mild fungistatic E. None of the above
properties.
A. Hydrogen peroxide topical solution 212. The study of flow which addresses the viscosity
B. Povidone iodine topical solution characteristics of powders, fluids and semisolids.
C. Chlorhexidine gluconate A. Stokes
D. Thimerosal topical solution B. Colligative properties
E. None of the above C. Embryology
D. Rheology
202. Component/s of douche powders EXCEPT E. Embryology
A. Boric acid
B. Zinc sulfate 213. Guidelines in packaging and storage of suspensions
C. Detergents EXCEPT
D. Sodium citrate A. Use wide mouth container
E. None of the above B. Adequate airspace above the liquid
C. Tight container
D. Clear bottle
203. Component/s of douche powder E. Protected from freezing
A. Boric acid D. Sodium chloride
B. Alum E. All of the above 214. A dispersion in which the dispersed phase is
C. Menthol composed of small globules of a liquid distributed
throughout a vehicle in which it is immiscible.
204. Medicinal substances employed topically in the mouth A. Suspension D. Emulsion
EXCEPT B. Magma E. Tincture
A. Benzocaine eugenol C. Gel
B. Sodium fluoride
C. Carbamide peroxide 215. In emulsion terminology, the dispersed phase is the
D. Parachlorophenol A. External phase
E. None of the above B. Internal phase
C. Continuous phase
205. Medical substances employed topically in the mouth. D. All of the above
A. Benzocaine E. None of the above
B. Camphorated parachlorophenol
C. Carbamide peroxide 216. Phases of emulsion EXCEPT
D. Lidocaine A. Dispersed phase
E. All of the above B. Dispersion medium
C. Emulsifying agent
206. The withdrawal of desired constituents from crude D. External phase
drugs through the use of selected solvents in which the E. None of the above
desired constituents are soluble.
A. Distillation D. Mixing 217. Continental method of emulsion preparation is also
B. Extraction E. Trituration referred as
C. Osmosis A. Dry gum method
B. 4:2:1 method
207. Concentrated preparations of vegetable or animal C. English method
drugs obtained by removal of the active constituents of the D. All of the above
respective drug with suitable menstrua E. A & B only
A. Percolates D. Fluidextracts
B. Macerates E. Solvents 218. Method which is useful for the extemporaneous
C. Extracts preparation of emulsions from volatile oils or oleaginous
substances of low viscosities.
208. Process in which a comminuted drug is extracted of its A. Forbes bottle method
soluble constituents by the slow passage of a suitable B. English method
solvent through the column of a drug. C. Dry gum method
A. Extraction D. Percolation D. Auxiliary method
B. Digestion E. Infusion E. Wet gum method
C. Maceration
219. Semisolid systems consisting of dispersion made up of
209. It is a process in which the properly comminuted drug either small inorganic particles or large organic molecules
is permitted to soak in the menstruum until the cellular enclosing and interpenetrated by a liquid.
structure is softened and penetrated by the menstruum and A. Suspension D. Collodion
the soluble constituents are dissolved. B. Gels E. Ointment
A. Infusion D. Percolation C. Emulsion
B. Maceration E. Extraction
C. Decoction 220. The taking up a certain amount of liquid without a
measurable increase in volume.
210. Preparations containing finely divided drug particles A. Imbibition D. Thixotropy
distributed uniformly throughout a vehicle in which the B. Swelling E. Xerogel
drug exhibits a minimum degree of solubility. C. Syneresis
A. Magma D. Suspension
B. Tinctures E. Gel 221. Taking up a liquid by a gel with an increase in volume
C. Emulsions A. Imbibition D. Thixotropy
B. Swelling E. Xerogel
 C. Syneresis B. Dip tube E. Actuator
C. Gasket
222. It occurs when the interaction between particles of the
dispersed phase becomes so great that on standing, the 233. Part of the usual aerosol valve assembly which are
dispersing medium is squeezed out in droplets and the gel made of plastic EXCEPT
shrinks. A. Actuator
A. Imbibition D. Thixotropy B. Housing
B. Swelling E. Xerogel C. Stem
C. Syneresis D. Mounting cup
E. Dip tube
223. A reversible gel sol with no change in volume or
temperature. 234. Temperature necessary to liquefy the propellant gas in
A. Imbibition D. Thixotropy aerosol
B. Swelling E. Xerogel A. 0°C and below
C. Syneresis B. -10°C to -15°C
C. -34.5°C to -40°C
224. It is formed when the liquid is removed from a gel and D. -15°C to -20°C
only the framework remains E. -20°C to -25°C
A. Imbibition
B. Swelling 235. Sterile, pyrogen limited preparations intended to be
C. Syneresis administered parentally
D. Thixotropy A. Aerosols
E. Xerogel B. Injections
C. Ophthalmic solution
225. Example/s of gelling agent D. All of the above
A. Acacia D. Ethylcellulose E. None of the above
B. Alginic acid E. All of the above
C. Bentonite 236. Small amount of powder may be blended by the
movement of a pharmaceutical spatula thru the powders on
226. Pressurized dosage forms that upon actuation emit a a sheet of paper or pill tile
fine dispersion of liquid and/or solid materials containing A. Spatulation D. Tumbling
one or more active ingredients in a gaseous medium. B. Trituration E. all of the above
A. Magma D. Aerosol C. Sifting
B. Gel E. Inhalant
C. Inhalation 237. Very fine powders intended for the different body
cavity such as ears, nose, throats, teeth and vagina.
227. Components of an aerosol formulation A. Douche powder
A. Product concentrate B. Dusting powder
B. Propellant C. Insufflations
C. Active ingredient D. Teas
D. All of the above E. Inhalations
E. None of the above
238. Study of particles
228. Liquefied gas propellants used in aerosol products A. Micromeritics
which are being phased out B. Micromerics
A. Dichlorodifluoromethane C. Micrometics
B. Difluoroethane D. Micromintics
C. Chlorofluorocarbon E. None of the above
D. Chlorofluorocarbon
E. Dichlorotetrafluoroethane 239. A thin semi-opaque paper having limited moisture
resistant qualities.
229. Part of the usual aerosol valve assembly that supports A. Simple white bond paper
the actuator and delivers the formulation in the proper from B. Vegetable parchment
to the chamber of the actuator. C. Glassine
A. Stem D. Mounting cup D. Waxed
B. Gasket E. Housing E. Colored bond paper
C. Spring
240. Tablets that are prepared by compressing granular
230. Part of the usual aerosol valve assembly that holds the effervescent salts or other materials having the capacity to
gasket in place and is the mechanism by which the actuator release gas (CO2) when in contact with water.
retracts when pressure is released, returning the valve to the A. Effervescent tablet
closed position. B. Press coated tablet
A. Stem D. Mounting cup C. Layered tablets
B. Gasket E. Housing D. Enteric coated tablets
C. Spring E. Multiple compressed tablets

231. Part of the usual aerosol valve assembly that is 241. Tablets prepared by compressing tablets to a special
attached to the aerosol can or container and holds the valve tablet machine and compressing another layer around the
in place. performed tablet.
A. Actuator D. Mounting cup A. Press coated tablet
B. Stem E. Spring B. Layered tablets
C. Gasket C. Melt-in-your mouth tablets
D. Multiple compressed tablets
232. Part of the usual aerosol valve assembly which E. Enteric coated tablets
extends from the housing down into the product and brings
the formulation from the container to the valve.
A. Stem D. Spring
242. Defined as solid dosage forms in which one or more A. Glycerogelatin D. Plaster
medication and/or inert substances are enclosed within a B. Sponge E. Paste
small shell or container of suitable forms of gelatin. C. Collodion
A. Capsule
B. Tablet 252. Plastic masses intended for topical application
C. Powder containing gelatin, glycerin, water and added medicinal
D. Caplet materials.
E. Both A and B A. Glycerogelatin
B. Gelatin
243. Disc-shaped, solid dosage form containing a medicinal C. TDDS
agent and flavoring agent, intended to be slowly dissolved D. Plasters
in the oral cavity or mouth for local effect. E. None of the above
A. Lozenges D. Caplet
B. Troches E. Both A and B 253. Common topical dusting powder to prevent irritation
C. Pills and chafing.
A. Tolnaftate powder
244. Sterile solutions that are compounded and package for B. Chloride powder
instillation into the eyes. C. Plain talcum powder
A. Ophthalmic solutions D. Nystatin powder
B. Ear preparations E. All of the above
C. Eye drops
D. Nasal preparations 254. Fabrics and/or film even coated on one side with a
E. Ophthalmic ointments pressure sensitive adhesive mixture.
A. Petrolatum gauze
245. Preservative mixture which is effective against some B. Absorbent gauze
strains of Pseudomonas aeruginosa, an organism that can C. Adhesive tapes
invade an abraded cornea and cause ulceration and D. Adhesive bandage
blindness. E. Gauze
A. Polymixin B, Benzethonium chloride
B. Benzalkonium chloride, Thimerosal 255. Contains 1% of liquefied phenol in calamine lotion
C. Benzalkonium chloride, Polyxmyxin B A. Phenolated calamine lotion
D. Phenyl mercuric nitrate, Chlorobutanol B. White lotion
E. Polymixin B and sodium benzoate C. Sulfur lotion
D. Calamine lotion
246. Ophthalmic preparation which is used to increase the E. All of the above
corneal contact time of a drug substance and thus provide a
more sustained action. 256. It is a process of comminution in which a paste is
A. Ophthalmic suspension formed by combining the powder material and a small
B. Ophthalmic ointment amount of liquid in which the powder is insoluble.
C. Ophthalmic drops A. Levigation
D. Ophthalmic solution B. Trituration
E. Otic suspension C. Spatulation
D. Sifting
247. Chloromycetin 1% ophthalmic ointment E. All of the above
A. Silver nitrate ophthalmic solution
B. Pilocarpine HCl Ophthalmic solution 257. Powders containing deliquescent and hygroscopic
C. Chloramphenicol Ophthalmic ointment materials should be wrapped in what kind of paper?
D. Naphazoline Ophthalmic solution A. Vegetable parchment
E. Polymixin B Ophthalmic solution B. Glassine paper
C. Bond paper
248. Preparations usually placed in the ear canal by drops D. Waxed paper
or in small amounts to remove excessive cerumen, treat ear E. Colored paper
infection, pain and inflammation.
A. Aural preparation 258. This type of coating imparts the same general
B. Ear preparation characteristics as sugar coating with the added advantage of
C. Nasal preparation a greatly reduced time period required for the coating
D. Ophthalmic preparation preparation.
E. Both A and B A. Enteric coating
B. Film coating
249. Most common preservative used in ophthalmic C. Multiple layer coating
preparations. D. Single layer coating
A. Benzalkonium chloride E. None of the above
B. Thimerosal
C. Chlorobutanol 259. This is a method of preparing tablets in which the
D. Both A and C powder mixture is compacted in large pieces and
E. All of the above subsequently broken down or sized into granules.
A. Wet granulation
250. Tinactin solution B. Dry granulation
A. Tolnaftate C. Direct compression
B. Povidone Iodine D. Slugging
C. Carbol-fuschin E. Compactness
D. Calcium hydroxide
E. Thimerosal 260. For some granular chemicals like potassium chloride,
this method of preparation of tablet is an advantage to use.
251. Liquid preparations composed of pyroxylin dissolve in A. Wet granulation
a solvent mixture equally composed of alcohol and ether B. Dry granulation
with or without added medicinal substances. C. Direct compression
 D. Geometric dilution C. 40%
E. Slugging
271. This type of suppository base includes mixtures of
261. This substance provides water solubility or fatty and water soluble bases. Example is Polyoxyl 40
permeability to the film to ensure penetration by body stearate.
fluids and therapeutic availability of the drug. A. Fatty base
A. Alloying substance B. Water miscible base
B. Plasticizer C. Water soluble base
C. Film former D. Miscellaneous base
D. Glossant E. None of the above
E. None of the above
272. Glyceryl monopalmitate is an example of this type of
262. Problem often encountered in film coating process suppository base
characterized by roughness of the tablet surface due to A. Fatty base
failure of spray droplets to coalesce. B. Water miscible base
A. Peeling C. Water soluble base
B. Picking D. Absorption base
C. Orange peel effect E. Greaseless
D. Bridging
E. None of the above 273. The most frequently employed method in the
preparation of suppositories both on small scale and on
263. Corresponds to the filling-in of the score line or industrial scale is:
intended logo on the tablet by the film. A. Molding
A. Peeling B. compression
B. Picking C. Hand rolling
C. Bridging D. Hand shaping
D. Mottling E. None of the above
E. None of the above
274. Water impurities like calcium and magnesium can be
264. Most common wall forming material used in removed by:
microencapsulation. A. Ion exchange
A. Lactose D. Dextrose B. Absorption
B. Gelatin E. None of the above C. Filtration
C. Sorbitol D. Distillation
E. All of the above
265. The following ointment base/s is/are classified as
hydrocarbon base/s: 275. The amount of preservative required to protect against
A. Petrolatum USP microbial growth varies with the proportion of water
B. White ointment available for growth. What is the usual effective
C. Polyethylene glycol ointment concentration of benzoic acid as preservative?
D. Both A and B A. 1% D. 0.01-0.02%
E. Both A and C B. 1-2% E. 0.001-0.002%
C. 0.1-0.2%
266. Polyethylene glycol is an example of
A. Hydrocarbon base 276. Relative sweetness of aspartame when compared to
B. Water removable base sucrose is
C. Absorption base A. 1:1 D. 300:1
D. Water soluble base B. 30:1 E. 500:1
E. All of these C.180:1

267. Petrolatum USP is: 277. Tinctures of potent drugs for which no proportion of
A. A purified mixture of semi-solid hydrocarbons active principles has been fixed, shall have the strength of:
from petroleum that has been wholly or nearly A. 10% by weight
decolorized B. 20% by weight
B. Also known as Yellow ointment C. 40% by weight
C. Also known as White ointment D. 50% by weight
D. Water soluble E. 60% by weight
E. None of the above
278. Peppermint spirit USP is prepared by:
268. Hydrophilic petrolatum USP is classified as: A. Solution with maceration
A. Hydrocarbon base B. Chemical reaction
B. Oleaginous base C. Distillation
C. Absorption base D. Fermentation
D. Water removable base E. None of the above
E. All of the above
279. Flexible collodion is prepared by adding castor oil and
269. Semi-solid preparations containing one or more camphor to collodion. How many % of castor oil is
medicinal agents dissolved or dispersed in either an oil-in- required in this preparation?
water emulsion or in another type of water washable base. A. 3% D. 0.5%
A. Creams D. Ointments B. 5% E. 0.005%
B. Gel E. All of the above C. 2%
C. Paste
280. Salicylic acid contains how many percentage of
270. How many percent of glycerin is contained in a salicylic acid in Flexible collodion?
glycerogelatin preparation? A. 3% D. 15%
A. 15% D. 5% B. 5% E. 20%
B. 35% E. 10% C. 10%
 290. These are thermodynamically stable, optically
281. Glycerin or glycerites contain ____ of glycerin transparent, isotropic mixtures of a biphasic oil-water
A. 50% D. 1% system stabilized with surfactants.
B. 25% E. 0.5% A. Microemulsion
C. 10% B. Auxiliary emulsion
C. w/o/w emulsion
282. These are concentrated preparations of vegetable or D. o/w emulsion
animal drugs obtained by the removal of the active E. w/o emulsion
constituents of the respective drugs with suitable menstrual
and evaporation of all or nearly all the solvent. 291. Mineral Oil emulsion is a/an:
A. Fluidextract A. o/w emulsion
B. Distillate B. o/w/o emulsion
C. Extractive C. w/o emulsion
D. Extraction D. w/o/w emulsion
E. None of these E. None of the above

283. This method of extraction is a process in which the 292. This is used for preparing fluidextracts with boiling
soluble constituents of a comminuted drug are extracted by water as the menstruum, alcohol being added as a
the slow passage of a suitable solvent through a column of preservative to the concentrated percolate.
the drug. A. Process A
A. Percolation B. Process B
B. Infusion C. Process D
C. Decoction D. Process E
D. Maceration E. Process M
E. Steam distillation
293. This is a percolation method that can be modified for
284. These preparations are made so that each mL contains fluidextracts that must be assayed.
the therapeutic constituents of 1 g of the standard drug that A. Process A
it presents. B. Process B
A. Fluid extract C. Process C
B. Macerate D. Process E
C. Extractive E. Process M
D. Infusate
E. Extract 294. Magnesium aluminum silicate, also known as veegum,
in concentrations of _____, forms firm, thixotropic gels.
285. Coarse dispersion includes: A. 10% D. 1%
A. Emulsion B. 5% E. 0.5%
B. Gel C. 2%
C. Magma
D. All of the above 295. Bentonite magma is a preparation of ___ bentonite a
E. None of the above native colloidal hydrates aluminum silicate in purified
water.
286. In emulsion terminology, the dispersed phase is A. 10% D. 1%
referred to as: B. 2% E. 0.5%
A. Internal phase C. 5%
B. External phase
C. Continuous phase 296. In moist heat sterilization, spores of which
D. Dispersion medium microorganisms are most commonly employed?
E. Both B and C A. Bacillus stearothermophilus
B. Bacillus subtilis
287. If the oleaginous phase is the internal phase, then the C. Bacillus pumilus
emulsion is referred to as: D. Clostridium botulinum
A. o/w emulsion E. None of the above
B. o/w/o emulsion
C. w/o emulsion 297. A rectal preparation for therapeutic, diagnostic, or
D. w/o/w emulsion nutritive purposes.
E. None of the above A. Enema
B. Elixir
288. This emulsifying agent has a disadvantage of C. Collodion
producing emulsions that are too fluid and which becomes D. Suppositories
more fluid upon standing. E. Foam
A. Gelatin
B. Casein 298. A solid or semisolid mass supplied on a backing
C. Egg yolk material and intended to provide prolonged contact with the
D. Bentonite skin.
E. None of the above A. Patch
B. Plaster
289. In a small scale extemporaneous preparation of C. Film
emulsion, these/this method/s may be applied: D. Foam
A. Dry gum method E. Gum
B. Wet gum method
C. Forbes method 299. It has been employed to study cerebral physiology and
D. All of the above a rapidly growing non invasive modality for the diagnosis
E. None of the above and management of cancer.
A. Positron emission tomography
B. Hydroxyl ethylene diphosphonate
C. Radiopharmacy
 D. Radiation
E. None of the above

300. Radiopharmaceutical drugs that are used for the

treatment of non Hodgkin lymphoma
A. Bexxar
B. Ceretec
C. Choletec
D. Prosta scint
E. Myoview