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BNB Pharmacy College Pharmaceutics Q&A

This document contains a question bank for the Pharmaceutics 1 course at Smt. B.N.B Swaminarayan Pharmacy College. It includes questions related to historical background of pharmacy, dosage forms, prescriptions, posology, pharmaceutical calculations, liquid and solid dosage forms, pharmaceutical incompatibilities, and semisolid dosage forms. The questions cover topics like classification of dosage forms, parts of a prescription, factors affecting drug doses, solubility enhancement techniques, types of emulsions and suspensions, suppository bases, and mechanisms of dermal drug penetration.

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Avinash Mansuk
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32 views6 pages

BNB Pharmacy College Pharmaceutics Q&A

This document contains a question bank for the Pharmaceutics 1 course at Smt. B.N.B Swaminarayan Pharmacy College. It includes questions related to historical background of pharmacy, dosage forms, prescriptions, posology, pharmaceutical calculations, liquid and solid dosage forms, pharmaceutical incompatibilities, and semisolid dosage forms. The questions cover topics like classification of dosage forms, parts of a prescription, factors affecting drug doses, solubility enhancement techniques, types of emulsions and suspensions, suppository bases, and mechanisms of dermal drug penetration.

Uploaded by

Avinash Mansuk
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Smt. B.N.

B Swaminarayan Pharmacy College, Salvav


*Dr. Kantilal Narkhede
BP103TP Pharmaceutics 1 Question Bank

Chapter 1: - Historical background and development of profession of pharmacy, Dosage


forms, Prescription, Posology:

1) Give a full introduction of Indian Pharmacopeia.(W2017)


2) Classify dosage forms in detail. Define Tablet, Capsule, Syrup and Ointment.
.(W2017)
3) What is posology? Discuss factors affecting posology.(W2018, 2017)
4) The prescription order requires 35% of dextrose solution in 1 liter, and pharmacy is
having 70% and 20% dextrose solutions. How much of 20% solution is required to fill
the order? (W2017)
5) Discuss various parts of prescription. (W2017,18,19, S18, S19)
6) Define the prescription. Discuss in detail parts of prescription. (W2018)
7) Explain various scope of pharmacy. (W2018)
8) Define pharmacopoeias. Discuss about IP. (W2018)
9) Define Posology. Explain various factors affecting on Posology. (W2018 S18)
10) Define prescription. Discuss the parts of prescription with drawing ideal
prescription.(W2018, 2019)
11) Discuss Scope and Potential of Pharmacy as Career. (W2018, 2019, S2019)
12) Explain in brief sources of errors in prescription. (S2018)
13) Write in detail about handling of prescription by Registered Pharmacist. (W2019)
14) Define posology. Discuss factors affecting doses. (W2019)
15) Give the classification of dosage forms with definitions. (S2019)
16) What is posology? Discuss the pediatric dose calculations based on age and body
weight. (S2019)
17) Define prescription. Explain in detail sources of errors in prescription. (W2021,
S2018)
18) Define and classify dosage form. Give importance of dosage form. (W2021)
19) Discuss scope of pharmacy. (W2021, 18, 19 S19)
20) Define posology. Explain in detail factors affecting dose of drug. (W17, 18, 21, S18)
21) Define pharmacopoeia. Explain Indian Pharmacopoeia in detail. (W 17,18,21)

Chapter 2: - Pharmaceutical calculations, Powders, Liquid dosage forms: -


Smt. B.N.B Swaminarayan Pharmacy College, Salvav
*Dr. Kantilal Narkhede
BP103TP Pharmaceutics 1 Question Bank

1) Write a short note on different weights and measures system. (W2017)


2) Write a short note on eutectic mixture. (W2017)
3) Discuss merits and demerits of liquid dosage forms. Enlist various excipients used in
preparation of liquid dosage forms. (W2017)
4) Calculate % strength of 65° o/p and 35° u/p. (W2017)
5) Discuss various solubility enhancement techniques of liquid dosage forms. (W2017)
6) Write down various methods used for calculating the dose for children and infant.
(W2018)
7) Find out the parts of 80% and 30% alcohol to supply 500ml of 50% alcohol. (W2018)
8) Define powder. Classify it and write its merits and demerits. (W2018, 17)
9) Define following terms (1) Dusting powder (2) effervescent powder (3) hygroscopic
powder (4) efflorescent Powder (5) eutectic mixture. (W2018)
10) Write a note on solubility enhancement techniques. (W2017, 18)
11) Define and classify the pharmaceutical incompatibility. Explain physical
incompatibility. (W2018)
12) Classify powders and briefly discuss surgical and medical dusting powders. (S2018)
13) Describe various techniques used for solubility enhancement. (W2017, W18, S18)
14) Convert 90% v/v and 40 % v/v alcohol in to proof strength. (S2018)
15) Calculate and suggest: (i) Calculate the quantity of sodium chloride required to
prepare 700 ml of a 0.9% solution? (ii) Find the strength of 85% v/v alcohol in terms
of proof spirit. (W2019)
16) How many mililitres of a 1:20 v/v solution of a drug can be prepared from 100 ml of
6% v/v solution. (W2019)
17) Discuss the imperial systems for weight and measures. ( W2017, S19)
18) Explain with examples: effervescent and efflorescent powders? (S2019)
19) Discuss the Geometric dilutions in powders and explain eutectic mixtures. (S2019)
20) What are the merits and demerits of liquid dosage forms? (W17, S2019)
21) Describe the calculation for isotonic solutions based on freezing point. (S2019)
22) Enlist various solubility enhancement technique. Explain any two in detail. ((W2017,
W18, S18,W21)
23) Write a note on effervescent powder. (W2021)
Smt. B.N.B Swaminarayan Pharmacy College, Salvav
*Dr. Kantilal Narkhede
BP103TP Pharmaceutics 1 Question Bank

24) Explain various weights and measure system. (W2021)


25) Find proof strength of 30%v/v and 90%v/v alcohol. (W2021)
26) Write a note on dusting powder (W2021)

Chapter 3:- Monophasic liquids, Biphasic liquids:

1) Differentiate between flocculated and deflocculated suspension. (W2017, 18, S18,


W21)
2) Discuss test for identification of emulsion. (W2017)
3) Define Gargles. Give method of preparation of it. (W2017)
4) Draw a label of Terpentine Liniment with full labeling requirements. (W2017)
5) Describe in detail Liniment and Lotions. (W2018)
6) Define suspension. Give its advantages and disadvantages. (W2018,21)
7) Define emulsion. Write its type. Explain various identification methods. (W2017, 18)
8) Enlist the methods used to prepared emulsion. Explain any one in detail. (W2018)
9) Discuss in detail stability problems of emulsion and describe the methods to
overcome it. (W2018)
10) Explain various test to be performed for identification of types of emulsion. . (W2017,
18, S18)
11) Distinguish the following pairs (S2018)
12) Lotions and Liniments 2) Mouth wash and throat paint
13) Differentiate the following: (i) Syrup I.P and Syrup U.S.P. (ii) Lotion and liniment.
(W2019).
14) Comments: (i) Syrup required preservative. (ii) Suspending agent is required in
Indiffusible mixture. (W2019)
15) Discuss the labeling requirement for elixir,linctuses and eye drops. . (W2019)
16) Write a note on flocculated and deflocculated suspension. (W2019)
17) Write a note on Nasal drops and Ear drops. (W2019)
18) Write a note on Gargles and mouthwashes.. (W2019)
19) Discuss the method of preparation for lotion and liniments. (S2019)
Smt. B.N.B Swaminarayan Pharmacy College, Salvav
*Dr. Kantilal Narkhede
BP103TP Pharmaceutics 1 Question Bank

20) Give the application site for followings: pessaries, enema, elixirs, gargles, 05 throat
paints. . (S2019)
21) Give the labeling requirements of enema, nasal drops, liniments, ointments and
suppository. (S2019)
22) How flocculated and deflocculated suspensions have been prepared? (W19,S2019)
23) Explain in brief: method of preparation of emulsion. (W2018,S19)
24) Differentiate between suspension and emulsion with examples. (S2019)
25) Define: i) syrup ii) Elixirs iii) lotions iv) gargles v) liniments. (W2021)
26) Write a note on identification test of emulsion (W2017, 18,21)
27) Explain different stability problems of emulsion (W2021, 18)
28) Give special labelling requirements for following: i) ear drop ii) Enema iii) Nasal
drops iv) linctus v) Emulsion (W2021)

Chapter 4:- Suppositories, Pharmaceutical incompatibilities:

1) Define Suppositories? Write a note on various bases used to prepare it. (W2017)
2) What is displacement value? How is it calculated? (W2017)
3) Discuss chemical incompatibility with examples. (W2017,S19)
4) Define suppositories. Enlist type of suppositories. Writes its advantages and
disadvantages. (W2018)
5) Write a short note on suppositories base. (W2018)
6) Define and classify the pharmaceutical incompatibility. Explain physical
incompatibility. (W2018)
7) Define Incompatibility. Enumerate various types of incompatibility and explain
various types of physical incompatibilities. (W 2018,S18)
8) Explain therapeutics incompatibility with suitable examples. (S18, W21)
9) Define Suppository. Describe various types of suppository bases with examples.
(W2018,S18)
10) Classify ointment base and discuss any one in detail. Classify methods to prepare
ointment. (W2019)
11) Discuss suppository bases with examples. (W2019)
12) Define suppository. Discuss methods to prepare suppositories. (W2019)
Smt. B.N.B Swaminarayan Pharmacy College, Salvav
*Dr. Kantilal Narkhede
BP103TP Pharmaceutics 1 Question Bank

13) Give a note on 'displacement value' considered in preparation of suppository. (S2019)


14) Define suppository. Explain in detail displacement value. (W2021)

Chapter 5: Semisolid dosage forms:

1) Give detail note on factor affecting penetration of drug through skin. (W2017)
2) Write a note on method of preparation of cream. (W2017)
3) Discuss various evaluation parameters of semisolid dosage forms. (W2017,18, S18)
4) Write a note on ointment base. (W2018)
5) Discuss in detail “jellies” one of the best promising semisolid dosage form. (W2018)
6) Explain various mechanisms and factors influencing penetration of drug through skin.
(S2018)
7) Comments: (i) Collapsible tubes are more preffered than glass jar for creams. (ii) Gels
and gellies are not required preservatives (W2019)
8) Classify ointment base and discuss any one in detail. Classify methods to prepare
ointment. (W2019,S19)
9) Explain the mechanisms of dermal penetration of drugs. (S2019)
10) Discuss the excipients used in semisolid dosage forms. (S2019)
11) Explain method of preparation of cream with example. (W2021)
12) Give outline for classification of semisolid dosage form. Explain factors affecting
dermal penetration (W2021,S18,17)
Smt. B.N.B Swaminarayan Pharmacy College, Salvav
*Dr. Kantilal Narkhede
BP103TP Pharmaceutics 1 Question Bank

Common questions

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Factors affecting posology include age, weight, sex, physiological state, pathological state, and drug interactions . Understanding these factors is crucial because they influence how individuals respond to medications, ensuring dosages are safe and effective. For instance, children and elderly people metabolize drugs differently, necessitating dosage adjustments .

Suppositories are advantageous for delivering medications directly into the systemic circulation, bypassing the gastrointestinal tract, which is beneficial for those with nausea or swallowing difficulties . However, they can be uncomfortable, have limited drug absorption variability, and require patients to adopt specific positions during administration . These factors impact their acceptability and convenience, often limiting their use to specific patient groups or conditions .

The Indian Pharmacopoeia (IP) sets the standards for drugs manufactured and consumed in India, ensuring safety, efficacy, and quality . Unique to India's legal pharmaceutical framework, it's periodically updated to incorporate new scientific knowledge and global practices. Unlike other pharmacopoeias which cater to multinational standards, IP focuses on India's specific needs and regulatory requirements .

To prepare a 0.9% sodium chloride solution, calculate the mass of sodium chloride needed per volume of solution, using the formula mass = concentration x volume . For example, 0.9g of NaCl per 100ml of water maintains isotonicity with body fluids. Precision is critical to ensure the solution's osmolarity matches physiological environments, preventing cell damage due to osmotic pressure imbalances .

Monophasic liquid dosage forms are homogeneous clear liquids containing the active ingredient dissolved in a suitable solvent, like syrups and solutions . Biphasic forms, such as emulsions and suspensions, consist of two phases - where the active ingredient is dispersed rather than dissolved . Monophasic forms offer consistent dosing and easier administration, while biphasic forms can deliver insoluble drugs and provide controlled release effects .

Pharmaceutical incompatibilities are classified as physical, chemical, and therapeutic . Understanding these classifications informs formulation by identifying potential adverse interactions, such as physical changes in the drug appearance or chemical reactions that alter drug efficacy . By anticipating incompatibilities during the formulation stage, pharmacists can modify excipients or buffer systems to ensure drug stability and efficacy .

Solubility enhancement methods include the use of surfactants, pH adjustment, co-solvents, and particle size reduction . Surfactants help by decreasing surface tension and improving wetting, while pH adjustment can increase solubility for ionizable drugs . Co-solvents like ethanol enhance solubility by altering solvent polarity. Each method has limitations; for instance, surfactants may cause irritation, and pH adjustment is limited by physiological constraints .

Common prescription errors include dosage mistakes, incorrect drug formulations, and administration route errors . Pharmacists can mitigate these by double-checking prescriptions, using standardized protocols for error prevention, and consulting with prescribers when discrepancies arise . Additionally, patient education on how to take medications accurately is crucial .

Flocculated suspensions contain particles that form loose aggregates, which settle rapidly but are easy to redisperse upon shaking . Deflocculated suspensions, on the other hand, have particles that settle slowly and form a compact sediment hard to redisperse . The choice between the two impacts the ease of dosing and patient compliance, as deflocculated suspensions are more likely to cause dosing inconsistencies .

Excipients in liquid dosage forms act as solvents, preservatives, flavoring agents, or viscosity enhancers, influencing the medication's stability, taste, and shelf life . For instance, preservatives prevent microbial growth, enhancing longevity, while viscosity enhancers maintain suspension uniformity, preventing sedimentation . The interplay of these excipients is critical for ensuring the therapeutic effectiveness and patient adherence to liquid medications .

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