HKDSE Biology Mock Exam Paper 1
HKDSE Biology Mock Exam Paper 1
BIOLOGY PAPER 1
HKDSE MOCK EXAM V
GENERAL INSTRUCTIONS
1 There are TWO sections, A and B, in this Paper. You are advised to finish Section A in about 35 minutes.
2 Section A consists of multiple-choice questions in this question paper. Section B contains conventional
questions printed separately in Question-Answer Book B.
3 Answers to Section A should be marked on the Multiple-choice Answer Sheet while answers to Section B
should be written in the spaces provided in Question-Answer Book B. The Answer Sheet for Section A and
the Question-Answer Book B for Section B will be collected separately at the end of the examination.
1 Read carefully the instructions on the Answer Sheet. After the announcement of the start of the examination,
you should first stick a barcode label and insert the information required in the spaces provided. No extra time
will be given for sticking on the barcode label after the ‘Time is up’ announcement.
2 When told to open this book, you should check that all the questions are there. Look for the words ‘END OF
SECTION A’ after the last question.
4 ANSWER ALL QUESTIONS. You are advised to use an HB pencil to mark all the answers on the Answer
Sheet, so that wrong marks can be completely erased with a clean rubber. You must mark the answers clearly;
otherwise you will lose marks if the answers cannot be captured.
5 You should mark only ONE answer for each question. If you mark more than one answer, you will receive
NO MARKS for that question.
Directions: Questions 1 and 2 refer to the electron micrograph below, which shows some cells in a
blood smear.
A 500X
B 1000X
C 2000X
D 5000X
A Different fruits contain different substances that prevent jelly from setting.
B Fruits contain substances that prevent jelly from setting.
C Kiwi fruits contain a substance that prevents jelly from setting.
D Kiwi fruits and pineapples contain the same substance that prevents jelly from setting.
5 Which of the following correctly shows the independent variable and dependent variable in the
experiment?
6 Three cells, P, Q and R, were left in distilled water or 10% sucrose solution for 10 minutes. The
cells were then examined under the microscope. The appearance of the cells is shown below.
A cell P only
B cell R only
C cell P and cell Q only
D cell Q and cell R only
(3) (4)
A stage (1).
B stage (2).
C stages (2) and (3).
D stages (3) and (4).
After a person drank the milk, digestion of the milk first took place in
A the mouth.
B the stomach.
C the duodenum.
D the ileum.
Directions: Questions 10 and 11 refer to the flow chart below, which shows the main processes
involved in human reproduction.
10 Which of the following types of cells have the highest percentage of cells carrying a
Y chromosome?
A sperm-producing cells
B sperms
C ovum-producing cells
D ova
11 What contraceptive methods can work by affecting processes (1) and (2) respectively?
(1) (2)
A tubal ligation diaphragm
B tubal ligation intrauterine device
C contraceptive pills diaphragm
D contraceptive pills intrauterine device
Which labelled sub-cellular structure(s) is/are abundant in the epithelial cell on the inner wall of the
small intestine?
A Y only
B X and Y only
C Y and Z only
D X, Y and Z
13 The diagram below shows a set-up for comparing the carbon dioxide content in inhaled air and
exhaled air. The hydrogencarbonate indicator was red in colour at the beginning. A student breathed
deeply and slowly through the mouthpiece.
What is the colour of the indicator in tubes A and B after the student had breathed a few times
through the mouthpiece?
Tube A Tube B
A red red
B yellow purple
C purple yellow
D red yellow
14 During which time period(s) is the amount of oxygen produced by the grass more than that used by
the grass?
A PW
B PQ and VW
C PR and UW
D RU
A M and Y
B N and X
C N and Z
D O and Z
What are the diploid number and haploid number of this animal?
20 Diagram I shows a man riding a bicycle. Diagram II shows the muscles in his left leg when he is
standing upright.
Diagram I Diagram II
A (1) only
B (3) only
C (1) and (2) only
D (1), (2) and (3)
Directions: Questions 22 and 23 refer to the diagram below, which shows some processes in the
nitrogen cycle.
A producer
B primary consumer
C secondary consumer
D decomposer
Which of the following eye defects can be corrected by the removal of part of the cornea shown?
A short sight
B long sight
C cataract
D colour blindness
(1) predation
(2) mutualism
(3) competition
A (1) only
B (1) and (2) only
C (1) and (3) only
D (2) and (3) only
26 The anticodon on a tRNA that carries the amino acid serine is AGU. What is the corresponding
triplet code on the coding strand of DNA?
A AGT
B AGU
C TCA
D UCA
A (1) only
B (3) only
C (1) and (2) only
D (1), (2) and (3)
Directions: Questions 28 and 29 refer to the diagram below, which shows the concentration of
substance X in a person’s blood. The person was infected by the same pathogen two
times within 80 days. The numbers of pathogens entering the body in the two
infections were the same.
A antigen
B pathogen
C antibiotic
D antibody
29 Which of the following statements about the immune response of the person is correct?
Which of the following correctly shows the cause of the change in blood glucose level between
7:00–9:00 and 9:00–11:00?
31 The number of people infected with malaria in a country has increased in recent years. Which of
the following are possible causes of this?
A (1) only
B (2) only
C (1) and (2) only
D (2) and (3) only
What is the factor limiting the rate of photosynthesis at point X and point Y?
Point X Point Y
A light intensity carbon dioxide concentration
B carbon dioxide concentration light intensity
C temperature light intensity
D carbon dioxide concentration temperature
34 The following are some processes in respiration or photosynthesis. Which of them produce ATP?
A 5 only
B 1 and 2 only
C 3 and 4 only
D 1, 2 and 5 only
– END OF SECTION A –
PAPER 1B
BIOLOGY PAPER 1
HKDSE MOCK EXAM V
SECTION B
Answer ALL questions. Put your answers in the spaces provided.
1 For each cell structure listed in column 1, select from column 2 one phrase that correctly
describes its property or function. Put the appropriate letter in the space provided. (3 marks)
Column 1 Column 2
B Lipid-soluble
b State one way in which we can reduce the chance of catching influenza. (1 mark)
a i Using letters in the diagram, list the structures that are involved in bringing
about breathing actions. (1
mark)
ii Does the diagram show the condition of inhalation or exhalation? Explain briefly.
(2 marks)
ii stages X and Y. (1
mark)
b i Which type of cell division does the cell undergo? Give an evidence provided
by the graph. (1
mark)
ii Suggest one type of cell in the human body that can undergo the type of cell
division in b i. (1 mark)
b What kind of data can be obtained from the sampling method in a but not from
using the transect alone?
(1 mark)
a State one observable feature from the photograph that indicates it is an insect-pollinated
flower. (1 mark)
ii 0.3 M (2 marks)
c What is the advantage of presenting the experimental results as a ratio of the initial
mass to final mass of the potato cylinders?
(1 mark)
a Name the part of the neurone that is surrounded by myelin sheath. (1 mark)
d Testing the knee jerk reflex is one of the diagnostic tests for multiple sclerosis. People
suffering from multiple sclerosis may show weak, absent or excessive responses.
i Describe how the test of knee jerk reflex is carried out. (2 marks)
ii Complete the diagram below to show the nervous pathway of the knee jerk reflex.
Label your drawings and use arrows to show the direction of nerve impulse
transmission. (2 marks)
He measured the movement of the air bubble in an hour when the fan was off. He then turned
on the fan and repeated the experiment. The table below shows his results.
d What assumption was made when this set-up was used for finding out the rate of
transpiration? (2 marks)
e After all the measurement was made, the student cut the leafy shoot at X. In the
following diagram, label and shade the part which was stained with dye solution.
(2
marks)
a Explain, with Mendel’s law of inheritance, why all the plants in F1 generation are
tall. (4
marks)
b In the 19th century, many scientists believed the Blending Theory which stated that
parental traits were mixed in the offspring.
i Do the results of Mendel’s experiment support the Blending Theory? Explain
your answer. (2 marks)
Describe how the results of this experiment differ from that of Mendel’s experiment.
Suggest a reason for the difference. (2 marks)
c Suggest a reason for changes in the density of yeast cell suspension between 15 and
30 hours after the experiment had started. (2
marks)
12 Phagocytes are a group of white blood cells that engulf and digest foreign particles found in
the blood. Describe how the sub-cellular structures of phagocytes are adapted for such
functions. (10 marks)
– END OF PAPER –
BIOLOGY PAPER 2
HKDSE MOCK EXAM V
INSTRUCTIONS
1 There are FOUR sections, A, B, C and D in this Paper. Attempt ALL questions in any TWO sections.
2 Write your answers in the Answer Book. Start each question (not part of a question) on a new page.
1 a The amount of water reabsorbed in the kidney tubules is controlled by the antidiuretic
hormone (ADH).
i State how ADH controls the amount of water reabsorbed in the kidney tubules.
(2 marks)
ii Mr Lee drank 0.5 L of water when he was at rest. The table below shows the changes
in the concentration of ADH in Mr Lee’s blood after drinking.
0
12.6
(water intake)
0.5 11.0
1 4.6
1.5 5.5
2 8.6
2.5 12.6
3 12.6
(1) Plot a graph to show the changes in the concentration of ADH in Mr Lee’s blood
as shown in the table above. (3 marks)
(2) Explain the changes in the concentration of ADH in the table above. (4 marks)
iii Miss Wong got a genetic disease. Her kidney tubules do not respond to ADH. What
health problems would result from the disease? (1 mark)
Some of these hormones can be used to produce fertility drugs. A doctor is going to
prescribe fertility drugs to three infertile women (X, Y and Z). The causes of infertility of
the women are listed below.
i State which of the hormones might be used to treat infertility in women X, Y and Z
respectively. Explain your answer. (6 marks)
ii Taking fertility drugs may increase the chance of multiple births. Why? (2 marks)
iii Among hormones A, B, C and D, two of them can also be used to produce
contraceptive pills. What are they? Describe how they can prevent pregnancy.
(2 marks)
2 a Read the article below and answer the questions that follow.
AQHIs are reported on a scale of 1 to 10 and 10+ in ascending degree of health risk.
They are calculated based on the health risks of four air pollutants, namely ozone, nitrogen
dioxide, sulphur dioxide and RSPs, at different concentrations. The AQHI informs the
public of the short-term health risk of air pollution and helps the public, especially those
with heart or respiratory diseases, take precautionary actions when necessary.
i Which two air pollutants constituting the AQHI are acidic gases? Describe their effects
on human health. (4 marks)
ii On the days with serious AQHI, the sky may be covered in smog.
(1) How do the air pollutants constituting the AQHI contribute to the formation of
smog? (2 marks)
(2) Suggest two precautionary actions that people with heart or respiratory diseases
should take on the days with serious AQHI. (2 marks)
iii Suggest two ways to reduce the concentrations of the air pollutants constituting the
AQHI. (2 marks)
ii A food chain rarely consists of more than five trophic levels. Why? (2 marks)
iii The aquatic environment of the ecosystem above was found to be contaminated with
DDT. DDT was a stable and persistant pesticide used by farmers on farmlands. Which
organism in the above food web may contain the highest concentration of DDT in its
body? Explain breifly. (4 marks)
iv Apart from pesticides, state another group of chemicals used in farming that can cause
chemical pollution of the aquatic environment. Describe its effect. (3 marks)
3 a A researcher carried out an experiment to study the oxygen requirements for the growth of
three species of microorganisms (X, Y and Z). She prepared three identical test tubes half-
filled with sterile nutrient broth and added the following substances to each of them:
a reducing agent which can reduce dissolved oxygen to water.
a dye which changes from colourless to pink in the presence of oxygen.
The researcher then inoculated microorganisms X, Y and Z into the three test tubes
respectively. After plugging the mouths of the test tubes with cotton wool, she incubated the
test tubes at 30 °C for 24 hours. The diagram below shows the results.
i Why did the researcher add the reducing agent and the dye to the nutrient broth?
(2 marks)
iii From the results, deduce the oxygen requirement of each species of the
microorganisms. Give a reason for each answer. (6 marks)
iv Certain anaerobic bacteria can infect us through a wound and produce toxins harmful
to our health. Such infections may be treated by hyperbaric oxygen therapy. This
involves a few daily sessions during which the whole body is exposed to oxygen at
high atmospheric pressure in a chamber for 150 minutes. Suggest how the therapy may
be useful in treating such infections. (2 marks)
i Urea is added to the culture medium for the production of lysine. Suggest a reason for
this. (1 mark)
iii The graph below shows the production of lysine by the bacteria in the fermenter.
Calculate the maximum hourly rate of lysine production. Show your working.
(2
marks)
iv The diagram below shows the metabolic pathways for the production of lysine and
another amino acid, threonine, in the bacteria.
A mutant strain of the bacteria does not produce the enzyme necessary for the
conversion of chemical Z to threonine. Give three reasons why this mutant strain is
more suitable for the industrial production of lysine. (3 marks)
New Senior Secondary Mastering Biology (Second Edition)
Mock Exam V Biology Paper 2 - 44 -
Oxford University Press 2014
SECTION D Biotechnology
Answer ALL parts of the question.
4 a The flow chart below shows a possible method to produce a calf with a high yield of milk.
i Explain why the calf produced using this method has a high yield of milk. (1 mark)
ii A body cell can be used instead of an ovum in step 2. Suggest an advantage of using an
ovum. (2 marks)
iii Suggest how several identical calves can be produced from the embryo formed in step
4. (2 marks)
iv Explain why it is difficult to produce a calf with a high yield of milk by allowing an
ovum of a cow with a high yield of milk to fuse with a sperm of a bull. (3 marks)
v Some people disagree with the production of calves using this method. State two
concerns these people have. (2 marks)
Before analysing the DNA samples by DNA fingerprinting, the scientist performed
polymerase chain reaction (PCR) to amplify the DNA samples.
ii During PCR, DNA samples were mixed with nucleotides, DNA polymerase and
primers, and put into a thermal cycler. The reaction mixtures were exposed to cycles of
heating and cooling. The graph below shows the temperature change in one cycle.
(1) Describe what happened to the DNA samples at stages X, Y and Z. (3 marks)
(2) DNA of other organisms may be present in sample (3). Explain why only DNA of
ladybirds is amplified. (3 marks)
The scientist suggested that ladybird P is a prey of ladybird Q. Why? Explain with
reference to the DNA fingerprints above. (2 marks)
– END OF PAPER –
Paper 1 Section B
Question 1 is a common item.
1 C 1m
B 1m
A 1m
Correct drawing and labels of sensory neurone and motor neurone (no interneurone) 1m
Correct directions of arrows 1m
Correct label 1m
Correct shading of xylem 1m
Correct title 1m
Correct choice of axes with correct labels and units 1m
Correct plotting and joining of line 1m
(2) After drinking 0.5 L of water, the water potential of the blood becomes higher than normal.
1m
The hypothalamus detects the rise in water potential of the blood and causes the pituitary gland
to release less ADH in the first hour after water intake. 1m
A smaller proportion of water is reabsorbed from the glomerular filtrate. The water potential of
the blood falls and returns to normal. 1m
Decreased water potential of the blood causes ADH concentration to increase and return to
normal level. 1m
iii She may suffer from dehydration / excessive loss of water in urine. 1m
b i Woman X: Hormone B 1m
Hormone B maintains the thickness of the uterine lining to prepare for implantation of the embryo.
1m
Woman Y: Hormone D 1m
Hormone D stimulates follicle development to produce mature ova. 1m
Woman Z: Hormone C 1m
Hormone C stimulates ovulation. 1m
ii Some fertility drugs stimulate a number of follicles to mature at the same time 1m
so that more than one ovum may be released from the ovaries at a time. 1m
iii Hormones A and B 1m
High levels of these hormones in blood inhibit secretion of hormones C and D such that follicle
development and ovulation do not occur. 1m
4 a i The calf carries the same genetic information as the cow with a high yield of milk. 1m
ii An ovum has a larger amount of stored nutrients 1m
for the development of the fused cell. 1m
iii Isolate individual cells from the embryo and grow each of them into an embryo. 1m
Transfer each embryo into a surrogate mother for development into an individual calf. 1m
iv Only half of the genetic information carried in the calf produced is the same as the cow with a high
yield of milk. 1m
If the sperm of the bull does not contain an allele for a high yield of milk, the calf may not have a
high yield of milk. 1m
Finding a bull containing an allele for a high yield of milk is difficult because bulls do not produce
milk. 1m
v The success rate is low. /
The calves produced may have birth defects or other health problems. /
Money should be better spent on other areas. /
Using this method to produce calves may decrease the genetic variations of the population.
(any 2 or other reasonable answers) 1m 2
b i Only a very small amount of DNA can be obtained from the ladybirds. 1m
PCR is needed to amplify DNA so that enough DNA can be obtained for DNA fingerprinting. 1m
ii (1) Stage X: The double helix of the DNA samples separated into two single DNA strands. / DNA
denaturation. 1m
Stage Y: Primers bound to the single-stranded DNA. 1m
Stage Z: Free nucleotides were added to the new DNA strands. 1m
(2) Primers used in PCR have a sequence complementary to the ends of the target region. 1m
DNA of other organisms does not have the sequence complementary to the primers. 1m
Primers cannot bind to the DNA of other organisms and thus the DNA of other organisms
cannot be amplified. 1m
iii The DNA fingerprint of sample (3) contains all the bands in the DNA fingerprint of sample (1). 1m
This indicates the gut content of ladybird Q contains ladybird P. 1m
Nitrogen dioxide can exacerbate respiratory problems by irritating lung tissues and causing or worsening conditions such as asthma and bronchitis. Long-term exposure can lead to decreased lung function and increased susceptibility to respiratory infections .
The mass of DNA changes between stages of cell division because, during the S phase of interphase, DNA replicates, thereby doubling its mass. As the cell enters mitosis, the replicated chromosomes are separated into daughter cells, returning the DNA mass to its original state in each resulting cell .
Osmosis causes potato cells to either gain or lose water when placed in different sucrose solutions. In a hypotonic solution (lower sucrose concentration), cells gain water and become turgid, while in a hypertonic solution (higher sucrose concentration), they lose water, leading to plasmolysis .
Self-pollination can lead to quick and uniform crop production, advantageous for maintaining specific traits. However, it may reduce genetic diversity, making crops vulnerable to diseases and environmental changes. Farmers might employ controlled cross-pollination to maintain genetic variety and crop resilience .
When a virus enters the human body, it is recognized as foreign by the immune system. This triggers a response wherein B cells produce specific antibodies against the virus. These antibodies bind to the virus, neutralizing it and marking it for destruction by phagocytes .
Transpiration rates in plants are influenced by environmental conditions such as humidity, temperature, and wind. For example, higher temperatures and wind speeds increase transpiration by causing more water to evaporate from the leaf surfaces, while high humidity decreases it as the air is already saturated with moisture .
Mendel's experiments showed that traits are inherited as distinct units (genes), rather than being blended. His cross-breeding of purebred tall and short pea plants resulted in all tall offspring (F1 generation), contradicting the Blending Theory which would predict medium height offspring .
Mimosa, a leguminous plant, plays a key role in the nitrogen cycle by housing nitrogen-fixing bacteria in its root nodules. These bacteria convert atmospheric nitrogen into ammonia, enriching the soil with nitrogen compounds that are usable by plants, thereby enhancing soil fertility .
The alveoli have a large surface area and thin walls. The large surface area allows for more gas exchange to occur, while the thin walls facilitate the diffusion of gases between the alveoli and capillaries .
Insect-pollinated flowers typically have bright colors, pleasant scents, and nectar to attract pollinators. These observable features help facilitate the transfer of pollen from one flower to another, ensuring reproductive success .









