0% found this document useful (0 votes)
98 views2 pages

Beverage Flavor and Hypertension Study Results

Two medical researchers conducted a clinical trial to test the effectiveness of a treatment for hypertension. 45 patients were randomly assigned to a placebo group (Group A) or treatment group (Group B). After 3 months, the average blood pressure change was -0.218 for Group A and 3.359 for Group B, with unequal variances of 16.81 and 21.19 respectively. Using a significance level of 0.01 and a t-test, the researchers found a statistically significant difference between the groups, thus supporting that the treatment was effective in lowering blood pressure.

Uploaded by

CARL JAMES
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
0% found this document useful (0 votes)
98 views2 pages

Beverage Flavor and Hypertension Study Results

Two medical researchers conducted a clinical trial to test the effectiveness of a treatment for hypertension. 45 patients were randomly assigned to a placebo group (Group A) or treatment group (Group B). After 3 months, the average blood pressure change was -0.218 for Group A and 3.359 for Group B, with unequal variances of 16.81 and 21.19 respectively. Using a significance level of 0.01 and a t-test, the researchers found a statistically significant difference between the groups, thus supporting that the treatment was effective in lowering blood pressure.

Uploaded by

CARL JAMES
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

1.

The research director of a leading beverage conducted a research to measure the


effectiveness of a new flavoring of its beverage compared to beverage with classical
flavoring. A sample of 20 persons tasted the beverage with the classical flavoring,
and 30 persons tasted the one with new flavoring. The participants were asked to
rate their enjoyment on the beverage, the highest score is 20 and the lowest is 0. 
The summary result of the study is shown below. Assuming equal variance and at
a .01 level of significance, is there significant difference between the enjoyment level
of the two differently flavored beverages?

Flavoring Sample Average enjoyment Variance

New 30 16.75 8.97

Classical 20 15.95 8.75

Null Hypothesis: There is no significant difference between the enjoyment level of the two differently
flavored beverages.

Alternative Hypothesis: There is significant difference between the enjoyment level of the two
differently flavored beverages

Level of Significance: 0.01/2 = 0.005

Df = n1-1 + n2-1 = 30-1 + 20-1 = 48

Critical Value: +2.682

Decision Rule: Reject the null hypothesis if t < -2.682 or t > 2.682; otherwise, do not reject the null
hypothesis.

Computation:
2
( n¿¿ 2−1)S2
S2 p=( n¿¿ 1−1) S21 + ¿¿
( 30−1 ) 8.97+ ( 20−1 ) 8.75
(n¿¿ 1−1)+(n¿¿ 2−1)= =8.8829166667 ¿ ¿
(30−1)+(20−1)

(xbar 1−xbar 2) (16.75−15.95)


t= = =0.93

√ 2 1 1
S p( + )
n1 n2 √ 1 1
8.8829166667 ( + )
30 20

Conclusion: Do not reject the null hypothesis, 0.93 < 2.682; which means there is no significant
difference between the enjoyment level of the two differently flavored beverages.
2. Two medical researchers looked into the effectiveness of a treatment for
hypertension or high blood pressure. In a clinical trial, 45 patients with hypertensions
were randomly assigned to either Group A (placebo control or Group B (treatment);
and were closely monitored for three months. After which, the researchers
measured and recorded the changes in the blood pressure of the patients in each
group.  The summary of the results is shown below.  Assuming unequal variance
and at .01 level of significance, is there evidence of significant difference on the
change in blood pressures of the two groups of patients?

Average change in blood


Groups Sample variance
pressure

A (placebo control) 21 -0.218 16.81

B (treatment) 24 3.359 21.19

Null Hypothesis: There is no evidence of significant difference on the change in blood pressures of the
two groups of patients

Alternative Hypothesis: There is evidence of significant difference on the change in blood pressures of
the two groups of patients

Level of significance: 0.01/2 = 0.005

Df = ¿ ¿

Critical Value: +2.695


Decision Rule: Reject the null hypothesis if t < -2.695 or t > 2.695; otherwise, do not reject the null
hypothesis.

( xbar 1−xbar 2 ) (−0.218−3.359 )


t= = =−2.757

√( ) √(
16.81 21.19
)
2 2
Computation: S S
1 2 +
+ 21 24
n1 n2

Conclusion: Reject the null hypothesis, -2.757 < -2.695; which means there is evidence of significant
difference on the change in blood pressures of the two groups of patients.

Common questions

Powered by AI

The decision rule was applied differently due to the variance assumption and the t-test requirements in each study. In the beverage study, equal variance was assumed, and the critical value for the t-test was set at 2.682. In contrast, the hypertension study assumed unequal variances, resulting in a different critical value of 2.695 for the t-test. These adjustments in the decision rule were necessary to accurately determine if the null hypothesis should be rejected based on the specific parameters and assumptions of each experiment .

The different levels of significance in the beverage and clinical trial studies could be attributed to the distinct purposes and contexts of the experiments, which influence the threshold for decision-making. In the beverage study, a higher tolerance for error might be acceptable due to the nature of consumer preference testing, while the clinical trial for hypertension requires stricter controls to ensure the health implications of the treatment are accurately assessed. The significance level (0.01 split into 0.005 for two-tailed tests) reflects the balance between avoiding Type I errors and the need for a higher certainty in critical health-related studies .

The decision rules in hypothesis testing for both studies are set by determining the critical values based on the chosen significance levels (0.01 split into 0.005 for two-tailed tests). This choice balances the probability of committing Type I errors—rejecting a true null hypothesis—with reasonable scientific rigor. For the beverage study, the critical value of ±2.682 reflects a relatively standard requirement in consumer research. The clinical trial demands a bit more stringency (critical value of ±2.695) due to health-related implications, minimizing false positives. These rules aim to provide reliable conclusions based on each study's objectives and constraints .

The sample size of each group affects the outcomes of the statistical tests by influencing the test's power and the estimated standard errors. In both studies, larger sample sizes could provide more reliable estimates, reducing the standard error and potentially identifying significant effects more easily. In the beverage study, the sample size disparity (30 vs. 20) could bias results towards the larger group. Similarly, balance in the hypertension groups (21 vs. 24) impacts reliability, where inconsistent sample sizes may obscure the true effects due to varying group standard deviations .

The beverage study concluded with failing to reject the null hypothesis because the statistical analysis showed that the difference in average enjoyment ratings between the classical and new flavors was not statistically significant at the specified significance level (t-value of 0.93 did not exceed critical value of 2.682). This indicates that the observed enjoyment difference, albeit higher for the new flavor, does not provide sufficient evidence to conclude it is truly better, acknowledging statistical variability and measurement error .

Assuming unequal variance in the hypertension treatment study impacts the power of the statistical test by necessitating a Welch's t-test, which is generally less powerful than a standard t-test for equal variance but more appropriate when variances differ. This adjustment provides a more reliable conclusion by reducing the risk of Type I errors associated with variance inequality. The study's result indicating a significant difference in blood pressure changes is therefore more credible due to this consideration, despite potential power decreases .

The assumed equal variance in the beverage study impacts the robustness of the findings by determining the type of statistical test used. The assumption of equal variance supports the use of a pooled variance t-test, which simplifies the computation and compares groups based on averaged data. This assumption may increase the risk of Type I or Type II errors if not met in reality, thus potentially affecting the robustness of the conclusion that no significant difference in enjoyment exists between the beverage flavors. A more rigorous test would analyze variance homogeneity before proceeding with assumptions .

The conclusion from the clinical trial results is that there is evidence of a significant difference in the change in blood pressures between the two groups (Group A with placebo and Group B with treatment). The statistical analysis supporting this conclusion involved a t-test for unequal variance, with a computed t-value of -2.757, which is less than the critical value of -2.695 at a 0.005 significance level .

To reach the conclusion in the clinical trial that there was a significant difference between the treatment and placebo groups, the calculations involved determining the t-value using the formula: t = (mean1 - mean2) / sqrt((S1^2/n1) + (S2^2/n2)), where mean1 and mean2 are the average changes in blood pressure for the placebo and treatment groups, respectively, and S1^2 and S2^2 are their variances. The resulting t-value of -2.757 was compared against the critical value of -2.695, leading to the rejection of the null hypothesis .

The calculated t-value for the enjoyment level of the two beverages is 0.93, which is less than the critical value of 2.682 at a significance level of 0.005. This comparison leads to the inference that there is no significant difference in enjoyment levels between the new and classical flavored beverages, so the null hypothesis is not rejected .

You might also like