Earth and Life Science

Quarter 2 – Module 25:

Benefits of Genetically Modified
Organisms
Personal Development
Alternative Delivery Mode
Quarter 2 – Module 25: Benefits of Genetically Modified Organisms
First Edition, 2020

Republic Act 8293, section 176 states that: No copyright shall subsist in any work of
the Government of the Philippines. However, prior approval of the government agency or office
wherein the work is created shall be necessary for exploitation of such work for profit. Such
agency or office may, among other things, impose as a condition the payment of royalties.

Borrowed materials (i.e., songs, stories, poems, pictures, photos, brand names,
trademarks, etc.) included in this module are owned by their respective copyright holders.
Every effort has been exerted to locate and seek permission to use these materials from their
respective copyright owners. The publisher and authors do not represent nor claim ownership
over them.

Published by the Department of Education

Secretary: Leonor Magtolis Briones
Undersecretary: Diosdado M. San Antonio

Development Team of the Module

Writers: Nerissa E, Manila
Editors: Melanie I. Samudio
Jocelyn M. Manset
Reviewer: Jason Ricaforte, Elizabeth A. Soriano
Princess Paolah L. De Guzman, Marissa C. Betchaida, Louie L. Alvarez
Gregorio M. De Chavez, Jr, Jocelyn M. Manset, Mario B. Maramot, Elaine T. Balaogan
Job S. Zape Jr.
Illustrator: Ednelinda Robles
Lovely Joy La Rosa, Charles Erick A. Jusay, Sandro Carlo B. Tablizo
Layout Artist: Anselma M. Ebero, Jocelyn M. Manset, Julie Anne V. Vertudes

Management Team: Wilfredo E. Cabral

Job S. Zape Jr.
Elaine T. Balaogan
Merthel M. Evardome
Nadine C. Celindro
Nicolas M. Burgos
Mario B. Maramot
Fe M. Ong-ongowan
Rosalinda A. Mendoza

Printed in the Philippines by ________________________

Department of Education – Region IV-A CALABARZON

Office Address: Gate 2 Karangalan Village, Barangay San Isidro

Cainta, Rizal 1800
Telefax: 02-8682-5773/8684-4914/8647-7487
E-mail Address: region4a@[Link]
Earth and Life Science
Quarter 2 – Module 25:
Benefits of Genetically Modified
Organisms
Introductory Message
For the facilitator:

Welcome to the (Earth and Life Science Grade 11) Alternative Delivery Mode
(ADM) Module on Benefits of Genetically Modified Organisms) !

This module was collaboratively designed, developed and reviewed by educators both
from public and private institutions to assist you, the teacher or facilitator in helping
the learners meet the standards set by the K to 12 Curriculum while overcoming
their personal, social, and economic constraints in schooling.

This learning resource hopes to engage the learners into guided and independent
learning activities at their own pace and time. Furthermore, this also aims to help
learners acquire the needed 21st century skills while taking into consideration their
needs and circumstances.

In addition to the material in the main text, you will also see this box in the body of
the module:

Notes to the Teacher

This contains helpful tips or strategies that
will help you in guiding the learners.

As a facilitator you are expected to orient the learners on how to use this module.
You also need to keep track of the learners' progress while allowing them to manage
their own learning. Furthermore, you are expected to encourage and assist the
learners as they do the tasks included in the module.

ii
For the learner:

Welcome to the Mathematics 7 Alternative Delivery Mode (ADM) Module on (Lesson

1: Genetic Engineering)!

The hand is one of the most symbolized part of the human body. It is often used to
depict skill, action and purpose. Through our hands we may learn, create and
accomplish. Hence, the hand in this learning resource signifies that you as a learner
is capable and empowered to successfully achieve the relevant competencies and
skills at your own pace and time. Your academic success lies in your own hands!

This module was designed to provide you with fun and meaningful opportunities for
guided and independent learning at your own pace and time. You will be enabled to
process the contents of the learning resource while being an active learner.

This module has the following parts and corresponding icons:

What I Need to Know This will give you an idea of the skills or
competencies you are expected to learn in the
module.

What I Know This part includes an activity that aims to

check what you already know about the
lesson to take. If you get all the answers
correct (100%), you may decide to skip this
module.

What’s In This is a brief drill or review to help you link

the current lesson with the previous one.

What’s New In this portion, the new lesson will be

introduced to you in various ways such as a
story, a song, a poem, a problem opener, an
activity or a situation.

What is It This section provides a brief discussion of the

lesson. This aims to help you discover and
understand new concepts and skills.

What’s More This comprises activities for independent

practice to solidify your understanding and
skills of the topic. You may check the
answers to the exercises using the Answer
Key at the end of the module.

What I Have Learned This includes questions or blank

sentence/paragraph to be filled in to process
what you learned from the lesson.

What I Can Do This section provides an activity which will

help you transfer your new knowledge or skill
into real life situations or concerns.

iii
 Assessment This is a task which aims to evaluate your
level of mastery in achieving the learning
competency.

Additional Activities In this portion, another activity will be given

to you to enrich your knowledge or skill of the
lesson learned. This also tends retention of
learned concepts.

Answer Key This contains answers to all activities in the

module.

At the end of this module you will also find:

References This is a list of all sources used in developing

this module.

The following are some reminders in using this module:

1. Use the module with care. Do not put unnecessary mark/s on any part of the
module. Use a separate sheet of paper in answering the exercises.
2. Don’t forget to answer What I Know before moving on to the other activities
included in the module.
3. Read the instruction carefully before doing each task.
4. Observe honesty and integrity in doing the tasks and checking your answers.
5. Finish the task at hand before proceeding to the next.
6. Return this module to your teacher/facilitator once you are through with it.
If you encounter any difficulty in answering the tasks in this module, do not
hesitate to consult your teacher or facilitator. Always bear in mind that you are
not alone.

We hope that through this material, you will experience meaningful learning and
gain deep understanding of the relevant competencies. You can do it!

iv
 What I Need to Know

This module was designed and written with you in mind. It is here to help you master
the nature of Earth and Life Science. The scope of this module permits it to be used
in many different learning situations. The language used recognizes the diverse
vocabulary level of students. The lessons are arranged to follow the standard
sequence of the course. But the order in which you read them can be changed to
correspond with the textbook you are now using.

The module has one lesson:

 Lesson 1 – Benefits of Genetic Engineering

After going through this module, you are expected to:

1. classify the situation given as a benefit or risk in using GMO
2. express one’s perception in the use of GMO

What I Know

Choose the letter of the best answer. Write the chosen letter on a separate sheet of
paper.
1. What do you call the technique wherein there is the transfer of genes from one
organism to another?
A. cloning C. inbreeding
B. genetic engineering D. selective breeding
2. What is the other term for genetically modified organism?
A. genetically spliced organism C. both a and b
B. transgenic organism D. none of a and b
3. What do you call the process of genetic engineering that is aimed for improving
health conditions in producing vaccines?
A. cloning C. recombinant DNA technology
B. gene splicing D. selective breeding
4. What is the term used for the ethical implications and applications of genetic
engineering?
A. bioethics C. biogenesis
B. biogenetics D. biosynthesis
5. What do you call the hybrid of tiger and lion?
A. gerlion C. lioner
B. liger D. tilion
 6. What do you call the transgenic organism that is injected with scorpion venom
aimed to kill caterpillars?
A. venomous cabbage C. venomous cotton
B. venomous corn D. venomous soy
7. What do you call the transgenic organism that contained human protein per
liter of milk and found to be more nutritionally balance?
A. transgenic cow C. transgenic spider
B. transgenic goat D. transgenic scorpion
8. What transgenic organism can produce a fluorescent protein in its fur?
A. luminous cat C. luminous goat
B. luminous cow D. luminous spider
For numbers 9-15, refer to the following choices.

A. Statement I is correct
B. Statement II is correct
C. Statement I and II are correct
D. Statement I and II are incorrect
______9. I. Genetically modified plants have created resistance to harmful
agents, enhanced product yield, and shown increased adaptability
for better survival
II. Recombinant DNA technology has applications in various area
like medicine focusing on the discoveries of medicine to cure and
improve human health and nutrition
_____10. I. Genetically modified organisms (GMO) are products of
recombinant DNA technology
II. Translated organisms are other term for genetically modified
organisms
______11. I. Corn Resistance to insect pests, specifically the European corn
borer, through expression of the insecticidal protein Cry1Ab
from Bacillus thuringiensis
II. Vaccines in Maize Hepatitis B virus surface antigen (HBsAg)
produced in transgenic maize induces immune response when
injected into mice.
______12. I. Synthesis of synthetic human hemoglobin and erythropoietin by
genetically modified bacteria
II. Human growth hormone which cure blood clotting among
arteries
______13. I. Human clotting factors have also been produced in the milk of
transgenic cows
II. “Pharm” animals were produced to synthesize pharmaceutical
products
______14. I. Crops like potato, tomato, soybean and rice are currently being
genetically engineered to obtain new strains with better nutritional
qualities and increased yield.
II. Angus cows give enhanced milk that can produce silk stronger
than steel
______15. I. Eherichia coli has injected human gene to produce hormone
insulin.
II. Liger is hybrid of tiger and lion.
 Lesson
Benefits of Genetic
1 Engineering
As defined Genetic engineering is the processes of changing the DNA in living
organisms to create something new. It involves artificial manipulation, modification,
and recombination of DNA or other nucleic acid molecules in order to modify an
organism or population of organisms.

Recombinant DNA technology has applications various area like medicine focusing
on the discoveries of medicine to cure and improve human health and nutrition
aimed to produce good quality and high quantity crops.

What’s In

Activity 1. Guess Me!

Directions. Answer the puzzle by writing your answers in the grid.

1 2 3

2
3

4
4

DOWN ACROSS
1. Enzymes that help cut and 1. Technology used to remove and insert
synthesize DNA nucleotide genetic sequences from and into other
sequences.

2. Process to produce identical 2. Organisms where the recombinant

organism without using gametes DNA is introduced usually bacteria.

3. Practiced to indirectly manipulate 3. Breeding of organism that are

genes focusing on the physical traits genetically similar to maintain desired
among organisms. traits.

4. DNA is cut out of one organism and 4. Technique used to compare DNA from
put into another organism two or more organisms.
 Notes to the Teacher
This module will help you to understand the concepts about the process of
benefits of genetic engineering. All parts are consist of activities. Be guided
with the instruction on how you will answer each. Expectedly you will meet
the target at the end of the module.

What’s New

Activity 2 Transgenic (GM) Organisms

Directions. Name the transgenic organism based from the description given by
filling up the missing letters.
1. __ __ A __ __ __ E taste of grapes but looks like apple

contained human protein per litre of

2. __ __ A __ __ __E __I __ __O__ milk and found to be more nutritionally
balance

3. __E __O__OU___ injected with scorpion venom aimed to

__A__ __ AG ___ kill caterpillars

4. B__N__N__ V__CC___N___ can produce virus proteins against

hepatitis and cholera

5. E___ ___ ___E__I __ __IA insulin gene is injected to bacteria to

___O___I produce hormone insulin

6. SP__D__R G___ ___T spider enhanced milk that can produce

silk stronger than steel

7. L__M__N__ __S C___T produce a fluorescent protein in its fur

8. L__G___R hybrid of tiger and lion

 What is It

The aim of planting genetically modified organism and its commercial use is to help
improve farming methods efficiently and productively. Some of the most common
crops are soybean, maize, cotton, canola, alfalfa, papaya, eggplant, potato, apple,
safflower, pineapple, and sugarcane.
Genetically modified plants have created resistance to harmful agents, enhanced
product yield, and shown increased adaptability for better survival. Recombinant
technology has been widely used in improving crop varieties. Several transgenic or
genetically modified organisms (GMO) have been produced. Genetically Modified
organism are also called transgenic organism, since genes are transferred from one
organism to another. Recombinant DNA technology is playing a vital role in
improving health conditions by developing new vaccines and pharmaceuticals. The
treatment strategies are also improved by developing diagnostic kits, monitoring
devices, and new therapeutic approaches. Synthesis of synthetic human insulin and
erythropoietin by genetically modified bacteria; human growth which cure stunted
growth; tissues plasminogen activator which dissolves blood clots among patients
who had heart attack; transgenic pigs used to produced human hemoglobin; human
clotting factors have also been produced in the milk of transgenic goats; production
of “pharm” animals to synthesize such as pharmaceutical products and production
of new types of experimental mutant mice for research purposes.

Production of human insulin in bacteria

The transfer of human gene to bacteria Escherichia coli aims to have a mass
production of human insulin to cure diabetes mellitus. Insulin gene is extracted from
a human cell and spliced into a plasmid vector before inserted into a bacterial cell.
The transgenic bacteria are selected and cultured to be able to increase its number
carrying human insulin gene. The bacteria are harvested, purified and packed for
human use.

List of genetically modified organisms

Purpose Plant Descriptions

Herbicide Soybean Glyphosate herbicide (Roundup) tolerance conferred by

tolerance expression of a glyphosate-tolerant form of the
plant enzyme 5-enolpyruvylshikimate-3-phosphate
synthase (EPSPS) isolated from the soil
bacterium Agrobacterium tumefaciens, strain CP4
Insect Corn Resistance to insect pests, specifically the European
resistance corn borer, through expression of the
insecticidal protein Cry1Ab from Bacillus thuringiensis
Altered fatty Canola High laurate levels achieved by inserting the gene for
acid ACP thioesterase from the California bay
composition tree Umbellularia californica
Virus resistance Plum Resistance to plum pox virus conferred by insertion of a
coat protein (CP) gene from the virus

Vitamin Rice Three genes for the manufacture of beta-carotene, a

enrichment precursor to vitamin A, in the endosperm of the rice
prevent its removal (from husks) during milling
Vaccines Tobacco Hepatitis B virus surface antigen (HBsAg) produced in
transgenic tobacco induces immune response when
injected into mice
Oral vaccines Maize Fusion protein (F) from Newcastle disease virus (NDV)
expressed in corn seeds induces an immune response
when fed to chickens
[Link]
crops-and-732/

Activity 3 Uses of Transgenic (GM) Organisms

Direction. Match the following genetically modified organism to its application by
writing on the space given. Write the letter that corresponds to your answer on the
space before the number
______1. Cotton A. Medicine/ Health Proposes
______2. Soy oil B. Energy sources
______3. Corn for livestock feeds C. Manufacturing products
______4. Large quantities of tomatoes D. Good yield/ Food supply
______5. Biodiesel and ethanol from corn E. High Quality Crops
______6. Drugs and genes
 What’s More

Bioethics is the study of controversial ethics brought about by advances in biology

and medicine. Bioethics is multidisciplinary. It blends philosophy, theology, history,
and law with medicine, nursing, health policy, and the medical humanities .
It is concerned with all the ethical questions that arise in the relationships among
life sciences and the cited fields. Bioethics is commonly understood that refers to the
ethical implications and application of the health-related life sciences including
biotechnology, such as cloning, gene therapy, life extension, human genetic
engineering. It promotes critic reflection about ethical conflicts, which are caused by
progressing in life science and medicine.

Activity 4 Benefit and Risk of GMO

Direction. Write the letter B if the statement given is a benefit while the letter R if it
is a risk from the use of genetically modified organism.
________1. Crops like potato, tomato, soybean and rice are currently being genetically
engineered to obtain new strains with better nutritional qualities and increased yield.
________2. Genetic engineering in food can be used to produce totally the same or
identical substances such as proteins and other food nutrients.
________3. Positive genetic engineering deals with enhancing the positive traits in an
individual like increasing longevity or human capacity while negative genetic
engineering deals with the suppression of negative traits in human beings like certain
genetic diseases.
________4. Genetic engineering in food involves the alteration of genes in crops.
________5. While increasing the immunity to diseases in plants, the resistance genes
may get transferred to the harmful pathogens.
________6. Genetic engineering can hamper the diversity in organisms.
________7. The genetic modification of foods can be used to increase their medicinal
value, thus making edible vaccines available.

What I Have Learned

1. Genetic Engineering is the process of changing the DNA in living organisms

to create something new.
2. Genetically modified organism is also called transgenic organism because
there was a transfer of genes from one organism to another.
3. Planting GMO and its commercial use improve farming methods efficiently
and effectively.
 4. Recombinant DNA technology is playing a vital role in improving health
conditions by developing new vaccines and pharmaceuticals.
5. Bioethics is the ethical implication and application of the health-related life
sciences biotechnology such as cloning, gene therapy, life extension, human
genetic engineering.

What I Can Do

Activity 6. What is your stand?

Directions. Below are some of the arguments about the use of transgenic organism.
In your own perspective, explain your answer in not more than 5 sentences.
1. Among the cited examples of GMO, which do you think is the most
beneficial?
2. If you are a farmer would you take the chance of growing crops that are
pest resistant? Why or why not?
3. Considering the knowledge gained in genetic engineering, would you try to
patronize GMO fruits and vegetables? Why or why not?
4. Is creating or altering genes of an organism a form of Blasphemy to the
creator (God)? Why?
5. Is genetic engineering morally permissible or not?

Assessment

Multiple Choice. Choose the letter of the best answer. Write the chosen letter on a
separate sheet of paper.

1. What do you call the process of manipulating genes in order to have the desired
trait?
A. artificial selection C. genetic engineering
B. cloning D. selective breeding
2. Which among the choices is the other term for genetically modified organism?
A. artificially selected organism C. selected organism
B. cloned organism D. transgenic organism
3. Which among the choices below is used for improving health condition by
producing vaccines and pharmaceuticals?
A. cloning C. recombinant DNA technology
B. gene splicing D. selective breeding
 4. Which is referred to as the ethical implications and applications of the
process of genetic engineering?
A. bioethics C. biogenesis
B. biosystematics D. biogenetics
5. What do you call the transgenic organism that taste of grapes but looks like
apple?
A. Aplgrapes C. grapple
B. Aplres D. legrapes

6. What is the transgenic organism that insulin gene is injected to produce

hormone insulin?
A. Amoeba proteus C. both and b
B. Escherichia coli D. none of a and b
7. What plant is used to produce virus proteins against hepatitis B?
A. alfalfa C. soy beans
B. corn D. tobacco
8. What animal is used to enhance milk to produce silk stronger than steel?
A. cow C. scorpion
B. lion D. spider
For numbers 9-15, refer to the following choices.

A. Statement I is correct
B. Statement II is correct
C. Statement I and II are correct
D. Statement I and II are incorrect
______9. I. Genetically modified plants have created resistance to harmful
agents, enhanced product yield, and shown increased adaptability
for better survival
II. Recombinant DNA technology has applications in various area
like medicine focusing in the discoveries of medicine to cure and
improve human health and nutrition
_____10. I. Genetically modified organisms (GMO) are products of
recombinant DNA technology
II. Translated organisms are other term for genetically modified
organisms
______11. I. Corn Resistance to insect pests, specifically the European corn
borer, through expression of the insecticidal protein Cry1Ab
from Bacillus thuringiensis
II. Vaccines in Maize Hepatitis B virus surface antigen (HBsAg)
produced in transgenic maize induces immune response when
injected into mice.
______12. I. Synthesis of synthetic human haemoglobin and erythropoietin
by genetically modified bacteria
II. Human growth hormone which cure blood clotting among
arteries
______13. I. Human clotting factors have also been produced in the milk of
transgenic cows
II. “Pharm” animals were produced to synthesize pharmaceutical
products
______14. I. Crops like potato, tomato, soybean and rice are currently being
genetically engineered to obtain new strains with better nutritional
qualities and increased yield.
III. Angus cow give enhanced milk that can produce silk stronger than
steel
______15. I. Eherichia coli has injected human gene to produce hormone
insulin.
II. Liger is hybrid of tiger and lion.

Additional Activities

1. Watch the video in the website:

[Link]
2. Show your learnings in the module by choosing from any of the platforms
suggested below to be uploaded in our Google Drive folder named as ELS1stQ
 an info graphics
 a one- page essay with maximum 300 words
What’s More What’s New What I Know
Activity 4
1. B 5. R Activity 2 1.B 9. C
2. B 6. R 1. grapple 2.B 10. A
3. B 7. B 2. venomous cabbage 3.C 11. A
4. R 3. Spider goat 4.A 12. D
Assessment 4. liger 5.B 13. B
1.C 9. C 5. luminous cat 6.A 14. A
2.D 10. A 6. Escherichia coli 7.A 15. C
3.C 11. A 7. transgenic cow 8.A
4.A 12. D 8. Banana vaccine What’s In
5.C 13. B Down
6.B 14. A Activity 3 1. restriction
7.D 15. C 1. C 2. cloning
8.C 2. C 3. artificial
3. C 4. gene
4. D Across
5. B 1. recombinant DNA
6. A 2. host
3. inbreeding
4. gel electrophoresis
Answer Key
References
Basco-Tiamzon, M.E. Z, Avissar, Y.,Choi J.,Desaix, J., Jurukovski V., Wise, R., Rye,
C. “General Biology 2 Senior High School Textbook” Published 2016 Vibal
Group, Inc.

Bayo-ang, R.B., Coronacion, M.L.G., Jorda, A.T., Restubog, A.J. “Earth and Life
Science for Senior High School” Published 2016 Educational Resources
Corporation

Commission on Higher Educvation. Earth and Life Science for Senior High School.
C.P. Garcia Ave., Diliman, Quezon City Philippines. Commission on Higher
Education, 2016

Phillips, T. “Genetically modified organisms (GMOs): Transgenic crops and

recombinant DNA technology. Nature Education 1(1):213” Published 2008
Accessed June 6, 2020
[Link] modified-
organisms-gmos-transgenic-crops-and-732/

What is Bioethics? Accessed June 4, 2020 [Link]

bioethics
For inquiries or feedback, please write or call:

Department of Education - Bureau of Learning Resources (DepEd-BLR)

Ground Floor, Bonifacio Bldg., DepEd Complex

Meralco Avenue, Pasig City, Philippines 1600

Telefax: (632) 8634-1072; 8634-1054; 8631-4985

Email Address: [Link]@[Link] * [Link]@[Link]