Point Loop Diuretics Thiazide Diuretics K+ Spearing Diuretics Carbonic anhydrase Inhibitor Osmotic Diuretics

Name 1. Frusemide 1. Hydrochlorothiazide 1. Spironolactone 1. Acetazolamide 1. Mannitol

6. Bendrofluazide
2. Torsemide 2. Chlorothiazide 7. Bendroflumethiazide 2. K+ canrenone 2. Methazolamide 2. Glucose
3. Bumetanide 3. Cyclopenthiazide 8. Indapamide 3. Triamterene 3. Ethoxyzolamide 3. Isosorbide
4. Ethacrynic acid 4. Polythiazide 9. Metolazone 4. Amiloride 4. Dorzolamide
5. Chlorthalidone 10. Xipamide 5. Dichlorphenamide
Indicati 1. Acute pulmonary oedema 1. First line anti-hypertensive drug 1. Given with K+ losing 1. Glaucoma 1. To produce dieresis
on 2. Acute left ventricular failure 2. Congestive cardiac failure diuretics to minimize 2. Acute mountain sickness (Increase urine
3. Acute renal failure 3. Nephrogenic diabetes insipidus hypokalaemia in oedema / [Decrease rate of CSF volume)
hypertension.
4. Oedema due to nephrotic syndrome / 4. Nephrolithiasis due to idiopathic hypercalciuria production] 2. To reduce
2. Primary hyper-
cardiac failure (Reduce calcium stone formation in urinary tract) aldosteronism (Conn's 3. Metabolic alkalosis intracranial pressure
5. Hyperkalemia 5. Oedema associated with cardiac failure and syndrome) 4. Urinary alkalization in aspirin 3. To decrease
6. Hypercalcemia nephrotic syndrome 3. Secondary hyper- poisoning intraocular pressure
aldosteronism (Heart 5. Epilepsy 4. Prevention of renal
failure, Hepatic cirrhosis, tubular necrosis in
Nephrotic syndrome) acute renal failure
4. Management of refractory
oedema
5. Diuretics of choice in
cirrhosis of liver.
Adverse 1. As related to renal action 1. Due to fluid and electrolyte imbalance 1. Hyperkalaemia 1. Metabolic acidosis 1. Dehydration
effect * Hyponatremia * Hyponatremia 2. Metabolic acidosis 2. Potassium depletion 2. Hypernatremia
* Hypokalemia * Hypokalaemia 3. Gynecomastia in male 3. Renal stone formation 3. Hyperkalaemia
* Hypocalcaemia * Hyperuricemia 4. Paraesthesia
(reversible) 4. Transient
* Hyperuricemia (Precipitate gout) * Hypercalcemia 5. Drowsiness
* Hypomagnesemia * Metabolic alkalosis 4. Decrease libido impotency, 6. Hypersensitivity reaction extracellular volume
* Metabolic alkalosis * Volume depletion Benign prostatic • Fever expansion
* Acute hypovolemia 2. Due to metabolic imbalance hyperplasia • Rash 5. Headache
2. Not related to renal action * Hyperglycaemia [avoided by insulin injection] 5. Menstrual irregularity 6. Nausea
* Ototoxicity (Reversible) * Hypercholesterolemia (3, 4, 5 due to steroid structure) 7. Vomiting
* Dermatological 3. Other 6. Kidney stone (Triamterene) 8. Pulmonary oedema
* Photosensitivity / Rash * Hypersensitivity 7. Acute renal failure (when
* Hematological * Bone marrow depression → Dermatitis / Necrotizing
combination of triamterene
* Blood dyscrasias (Eosinophilia) Vasculitis
* Dermatological → Rash / Photosensitivity with indomethacin)
* Sexual → Decrease libido / Impotency
Contra 9. Borderline renal failure, heart failure 1. Renal insufficiency 1. Fatal hyperkalaemia 1. Liver cirrhosis 1. Anuria (risk of cardiac
indicati 10. Liver cirrhosis 2. Diabetes mellitus 2. Chronic renal insufficiency 2. Hepatic encephalopathy failure)
on 11. Severe volume and sodium depletion 3. Gout 3. Liver disease 2. Pulmonary oedema and
congestion
12. Pregnancy 4. Hepatic cirrhosis 4. Peptic ulcer disease
3. Dehydration

Md. Sherajul Haque 1

Md. Sherajul Haque 2