A Thesis on
DESIGN AND EVALUATION OF MOUTH DISSOLVING FILMS FOR
GRANISETRON IN THE MANAGEMENT OF CHEMOTHERAPY INDUCED
VOMITING
Dissertation submitted to
Jawaharlal Nehru Technological University Kakinada, Kakinada
In Partial Fulfillment for the Award of the Degree of
Bachelor of Pharmacy
By
P. Sai Sudheeksha (169V1R0057)
R. Pratyusha (169V1R0058)
R. Bhavana (169V1R0059)
S. Bhavana Durga (169V1R0060)
Under the Guidance of
Dr . P. Bharghava Bhushan Rao [Link].,Ph.D.
ASSOCIATE PROFESSOR
DEPARTMENT OF PHARMACEUTICS
V. V. INSTITUTE OF PHARMACEUTICAL SCIENCES
GUDLAVALLERU - 521 356, A.P.
2019-2020
V. V. Institute of Pharmaceutical Sciences
SeshadriRao Knowledge Village, GUDLAVALLERU- 521 356, Krishna District, A.P.
(Approved by AICTE & PCI, New Delhi and Affiliated to JNTUK, Kakinada)
Sponsored by A.A.N.M. & V.V.R.S.R. Educational Society
Ph. No. : 08674-274649, Fax: 08674-274441
E-mail: venkatadripharmacy@[Link], Website: [Link]
CERTIFICATE
This is to certify that the dissertation entitled “DESIGN AND EVALUATION OF
MOUTH DISSOLVING FILMS FOR GRANISETRON IN THE MANAGEMENT OF
CHEMOTHERAPY INDUCED VOMITING ”done for the partial fulfilment for the award
of degree of Bachelor of Pharmacy has been carried out by P. SAI SUDHEEKSHA, R.
PRATYUSHA, R. BHAVANA, S. BHAVANA DURGA under the supervision and guidance
of Dr.P. BHARGHAVA BHUSHAN RAO ASSOCIATE PROFESSOR in the Department
of Pharmaceutics at V. V. Institute of Pharmaceutical Sciences during the year 2019-2020
affiliated to the Jawaharlal Nehru Technological University Kakinada, Kakinada.
Place: Gudlavalleru Dr. A. LAKSHMANA RAO, [Link].,Ph.D.
Date: (PRINCIPAL)
V. V. Institute of Pharmaceutical Sciences
SeshadriRao Knowledge Village, GUDLAVALLERU- 521 356, Krishna District, A.P.
(Approved by AICTE & PCI, New Delhi and Affiliated to JNTUK, Kakinada)
Sponsored by A.A.N.M. & V.V.R.S.R. Educational Society
Ph. No. : 08674-274649, Fax: 08674-274441
E-mail: venkatadripharmacy@[Link], Website: [Link]
CERTIFICATE
This is to certify that the dissertation entitled “DESIGN AND EVALUATION OF
MOUTH DISSOLVING FILMS FOR TWO DRUGS IN THE MANAGEMENT OF
CHEMOTHERAPY INDUCED VOMITING ”done for the partial fulfilment for the award of
degree of Bachelor of Pharmacyhas been carried out by P. SAI SUDHEEKSHA , R.
PRATYUSHA ,R. BHAVANA ,S. BHAVANA DURGA under the supervision and
guidance of Dr . P. BHARGHAVA BHUSHAN RAO [Link].,Ph.D. ASSOCIATE
PROFESSOR in the Department of Pharmaceutics at V. V. Institute of Pharmaceutical Sciences
during the year 2019-2020 to the Jawaharlal Nehru Technological University Kakinada, Kakinada.
Place: Gudlavalleru Dr . P. Bharghava Bhushan
Rao
Date: RESEARCH GUIDE
DECLARATION
We hereby declare that the dissertation entitled “DESIGN AND EVALUATION OF MOUTH
DISSOLVING FILMS FOR TWO DRUGS IN THE MANAGEMENT OF
CHEMOTHERAPY INDUCED VOMITING”was carried out by us at V. V. Institute of
Pharmaceutical Sciences, Gudlavalleru under the esteemed guidance of Dr . P.
BHARGHAVA BHUSHAN RAO [Link].,Ph.D. , ASSOCIATE PROFESSOR
Department of Pharmaceutics , V. V. Institute of Pharmaceutical Sciences, Gudlavalleru. The extent
and source of information derived from the existence literature have been indicated through the
project work at appropriate places. The work is original and has not been submitted in part or full
for any diploma or degree of this university or any other university.
P. Sai Sudheeksha (169V1R0057)
R. Pratyusha (169V1R0058)
R. Bhavana (169V1R0059)
S. Bhavana Durga (169V1R0060)
ACKNOWLEDGMENTS
I am deeply indebted to Dr. A. LakshmanaRao,[Link]., Ph.D. Professor & Principal of V.
V. Institute of Pharmaceutical Sciences, Gudlavalleru & my research guide,
Dr . P. BHARGHAVA BHUSHAN RAO [Link].,Ph.D. , ASSOCIATE PROFESSOR
Department of Pharmaceutics , V. V. Institute of Pharmaceutical Sciences, Gudlavalleru. under
whose able and valuable guidance, this entire research work was successfully completed. I am
thankful for his constant source of encouragement and support, which provided to impetus and
paved the way for the successful completion of the research work.
I take this opportunity to express sincere thanks to Mr. [Link] Kumar Lab Assistant of
Pharmaceutics department for his help during experimental work.
I express my sincere thanks to other faculty members for their support and their help during
the course of study and to carry out this project work.
I am very grateful to classmates and friends who have been given a constant inspiration which
enabled me to reach this exuberant moment of my life.
I am indebted to the management “V. V. Institute of Pharmaceutical Sciences & A.A.N.M.
& V.V.R.S.R. Educational Society, Gudlavalleru” for providing me the necessary infrastructural
facilities to carry out the project work.
And above all, words fail to express my feeling to my parents whose initiation, constant
source of inspiration and encouragement throughout this course.
P. Sai Sudheeksha (169V1R0057)
R. Pratyusha (169V1R0058)
R. Bhavana (169V1R0059)
S. Bhavana Durga (169V1R0060)