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B.Sc. Bioinformatics Syllabus - Semester I

This document outlines the syllabus for the first semester of a B.Sc. in Bioinformatics. It covers 4 units: 1) introduction to genetics including Mendelian genetics and genetic mapping; 2) structure and function of DNA, RNA, replication, and transcription; 3) structure and properties of amino acids and proteins including primary, secondary, tertiary, and quaternary structure; 4) chemical and enzymatic synthesis of DNA and RNA as well as purification techniques like gel electrophoresis and blotting. The semester concludes with 4 practical experiments involving protein and DNA isolation. Recommended textbooks are also listed.

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Aqii Lone444
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45 views1 page

B.Sc. Bioinformatics Syllabus - Semester I

This document outlines the syllabus for the first semester of a B.Sc. in Bioinformatics. It covers 4 units: 1) introduction to genetics including Mendelian genetics and genetic mapping; 2) structure and function of DNA, RNA, replication, and transcription; 3) structure and properties of amino acids and proteins including primary, secondary, tertiary, and quaternary structure; 4) chemical and enzymatic synthesis of DNA and RNA as well as purification techniques like gel electrophoresis and blotting. The semester concludes with 4 practical experiments involving protein and DNA isolation. Recommended textbooks are also listed.

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Aqii Lone444
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We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd

THE CLUSTER UNIVERSITY OF SRINAGAR

Syllabus for [Link]. Ist Year (Semester –I)


Subject: Bioinformatics.
(Session- 2017-2018)

Semester I
Unit I

Introduction to genetics and lts importance: Mendelian genetics, Population genetics and lts
applications. Gene concept, alleles, transposable elements. Genetic linkage and mapping, brief
idea of genetic disorders.

Unit II

DNA: Nucleotides and Nucleosides, DNA Structure, non-coding and coding DNA, repeated
sequences, satellite DNA, tandem repeats, VNTRs, junk DNA, palindromes, inverted repeats.
Conformations A, B, C and Z). Super- coiling of DNA (Linking No., Twisting, Contour length)
RNA, and its types and functions. tRNA Structure and function. DNA replication,
transcriptional, post transcriptional modifications, translation.

Unit III

Amino acids, Structure, classification and properties. Levels of protein structure, importance and
determination of primary structure. Secondary structure (Alpha helix, Beta sheet and beta turns).
Characteristics of peptide bond (ᵠ and Ф bonds). Super secondary structures, protein domains.
Tertiary structure of proteins. Quartenary structure of Proteins.

Unit IV

Chemical and enzymatic synthesis of DNA and RNA. Purification of Nucleic acids. Gel
electrophoresis, Blotting techniques and hybridization. DNA finger printing, foot printing, PCR
and Chromosome walking. DNA sequencing.

Practicals:
1. Estimation of Proteins by Lowry’s method.
2. Isolation of DNA from Bacterial Cells.
3. Isolation of DNA from Plant Cells.
4. Isolation of DNA from Blood.

Books Recommended:
1. Genetics : A Conceptual Approach: Benjamin A pierce.
2. Instant Notes in Molecular Biology: Phil Turner et al.,
3. Applied Molecular Genetic: Roger I Miesfeld.
4. Molecular Biology: David P Clark.

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