Drugs for Bacteria

Nafcillin/oxacillin S Aureus
Penicillin  Strep A pyogenes
 Strep Pneumoniae
 Strep Viridans (G)
 Clostridium Perfringens (Clinda)
 Clostridium tetani. (metronidazole)
 Actinomyces israelii (V)
 P aeruginosa (antipseudomonal + aminoglycoside/fluoroquinolone)
 EPEC
 Treponema pallidum (benzathine)
 Leptospira interrogans (G; or doxycycline)
Ampicillin/aminoglycoside  Strep Agalactiae
 Listeria (gentamycin)
 Yersinia pestis
Ciprfloxacin  Bacillus anthracis (doxy)
Metronidazole  C Difficile
 Gardnerella (or clindamycin)
 Bacteroides fragilis (or clindamycin or cefoxitin)
 Porphyromonas
 Prevotella
 Fusobacterium
Erythromycin  C diphtheria
 B pertussis
 Chlamydophila pneumoniae (or azithro, clarithro)
 Mycoplasma pneumoniae (or azithro, clarithro)
 Ureaplasma urealyticum (or tetracycline)
Sulfonamides  Nocardia (TMP-SMX)
Rifampin, isoniazid, pyrazinamide,  M TB
ethambutol (RIPE)
Cephalosporin  N meningitis (ampicillin, cefotaxime, ceftriaxone)
 N gonorrhea (ceftriaxone)
 Haemophilius influenza (cefotaxime, ceftriaxone)
 Haemophilius ducreyi (ceftriaxone, ciprofloxacin, azithromycin)
 HACEK
 E-coli neonatal meningitis (ceftriaxone)
 Klebsiella pneumoniae
 Aeromonas (cefixime)

Amoxi-clav  Moraxella catarrhalis (cephalosporin)
 Pasteurella multocida
Fluoroquinolone  Legionella (levofloxacin/ azithromycin (macrolide))
 HACEK
 EColi UTI, septicemia (or sulfonamide)
 Yersinia enterocolitica – IC (or cephalosporin)
 Proteus mirabilis/vulgaris
 Salmonella enterica typhi (or cephalosporin)

Streptomycin  Francisella tularensisi
Azithromycin  Bartonella henselae (or doxy)
 Chlamydia trachomatis (or doxy)
Rifampin  Brucella (+doxy/ cotrimoxazole)
Omeprazole + amoxi +  H pylori
clarithromycin
Doxycycline  Klebsiella granulomatis
 Borelia burgdorferi
 Chlamydophila psittaci
 Rickettsia rickettsia
 Coxiella burnetii
Nothing  Salmonella other than typhi
Virus Drugs
IFNa+RTI  Hep B
Elbasavir/grazoprevir;  Hep C
ledipasvir/sofosbuvir
Cidofovir  HPV
 Adenovirus (IC)
 Molluscum contagiosum (IC) (or ritonavir)
Acyclovir  HSV-1/2 (or famciclovir, valacyclovir, penciclovir)
 VZV (oral – healthy, IV – IC)
Ganciclovir/foscarnet  CMV (IC)
Ribavirin  SARS-CoV (and IFN)
 Measles (experimental)
 RSV (and palivizumab)
 Arenaviridae (lumphocytic choriomengitis, lassa fever)
hRIG  Rabies (prophylaxis)
Amantadine/rimantadine  Influenza virus (or zanamivir/oseltamivir)
Nothing  Hep A
 Hep D
 Hep E
 B19
 JC
 BK
 EBV
 CMV
 HHV-6/7
 HHV-8
 Small pox
 Molluscum contagiosum
 Calicivirus (Norwalk)
 Bunyaviridae (California and lacrosse encephalitis,
hantavirus)
 Pircorna (Polio, Coxsackie a/b, D68, Echovirus,
Rhinovirus, HAV)
 Flaviviridae (st louis encephalitis, west nile
encephalitis, dengue, yellow fever, zika)
 Togaviridae (EEE, VEE, WEE, chikungunya, rubella)
 SARS-CoV
 Measles
 Mumps
 Parainfluenza
 Rabies
 Ebola (or favipiravir, brincidofovir)
 Reoviridae (Rotavirus, reovirus)
Drugs for Fungi
Selenium sulfide  Malassezia furfur
Imidazole  Dermatophytes (or tolnaftate)
 Candida albicans (or nyastatin)
Amphotericin B  Sporothrix schenckii (or itraconazole)
 Histoplasma capsulatum (or itraconazole if mild)
 Coccidioides immitis (or itraconazole if mild)
 Blastomyces dermatitidis (or itraconazole if mild)
 Aspergillus fumigatus (ABPA)
 Candida albicans (dessiminated; or fluconazole)
 Mucor, rhyzopus, absidia (zygomycophyta)
Voriconazole  Asperigillus fumigatus (invasive/aspergilloma)
AMB+5FC (flucytosine)  Cryptococcus neoformans (then fluconazole)
Trimethoprim/sulfamethoxazole  Pneumocystis jirovecci (dapsone if severe)

Drugs for Parasite

Metronidazole  Entamoeba histolytica (then iodoquinol)
 Giardia lamblia
 Trichomonas vaginalis
Azithromycin  Cryptosporidium (or nitrazoxanide, puromycin)
TMP-SMX  Isospora belli (or pyrimethamine/sulfadiazine)
 Cyclospora cayetanensis
Amphotericin B  Naegleria
Miconazole/propamidine  Acanthamoeba
isethionate
Chloroquine PO4 then primaquine  Plasmodium vivax
 Plasmodium ovale
 Plasmodium malariae (no prima)
Benzimidazole  Trypanosoma cruzi
Suramin  Trypanosoma brucei gambiense; trypanosoma b
rhodesiense (melarosoprol if chronic)
Stibogluconate  Leishmanial donovani
 Leischmania
 Leishmanial braziliensis
Clindamycin  Babesia (+ quinine)
Pyrimethamine  Toxoplasma gondii (+sulfadiazine)
Praziquantel  S mansoni; Schistosoma japonicum
 Schistosoma haematobium
 Clonorichis sinensis
 Taenia saginata
 Taenia solium
 Diphyllobothrium latum
 Echinococcus multilocularis
Albendazole  Echinococcus granulosus
Trimeprazine  Non-human schistosomes
Nothing  Microsporidia
 Plasmodium falciparum
Virulence Factor for Bacteria

Media for Bacteria

Organism Medium
Anaerobes Thioglycolate
Corynebacterium Loffler’s coagulated serum medium (S)
Tellurite agar (D)
Enteric bacteria Eosin methylene blue (EMB) (D)
MacConkeys
Enteric pathogens Hektoen enteric agar )D_
Xylose-lysine-deoxycholate agar
V Cholerae (likes alkaline) Thiosulfate Citrate Bile salts sucrose agar
(TCBS) (S)
Legionella Charcoal yeast extract (CYE) (S)
Mycobacterium Lowenstein Jensen medium (S)
Neisseria (sterile), Haemophilus Chocolate agar
Neisseria (flora) Thayer Martin (S)