[Link]

id=9979
• Advert number: 168151-0
• Posted Date: 09/06/08
• Closing Date: 18/07/08
National Institute for Health Research
NIHR Biomedical Research Centre
for Ophthalmology
Moorfields Eye Hospital NHS Foundation Trust
and UCL Institute of Ophthalmology
City Road, London EC1V 2PD
CLINICAL LECTURESHIP IN OPHTHALMIC
TRANSLATIONAL RESEARCH – REF: D4/91
The National Institute of Health Research (NIHR) Specialist Biomedical Research
Centre (BMRC) at Moorfields Eye Hospital/UCL Institute of Ophthalmology is one of
six new specialist BMRCs in the UK. The partnership has an outstanding track
record of basic biomedical research, much of which has led to translational programmes and
innovations that have already benefited large numbers of patients in
the United Kingdom and around the world. The juxtaposition of a huge and
unique clinical resource at one of the largest and the longest established eye hospitals
in the world, together with one of the largest eye research institutions with
40 academic staff, has led to a wide range of ground breaking biomedical research
firmly embedded in an appreciation of important clinical problems. The site is one
of the most productive and pre-eminent ophthalmological research sites in the
world. The Moorfields Eye Hospital/UCL Institute of Ophthalmology BMRC focuses
on five research themes: Age-related macular degeneration, Diabetes, Glaucoma,
Ocular Surface Disease, and Paediatric Ophthalmology and Inherited Eye Disease.
This is not exclusive for applicants.
[Link]
We are seeking to appoint four Clinical Lecturers to posts in 2009 (with 2 further
posts to be advertised in the future) to undertake translational biomedical
research in both clinical and research settings included within the Centre. The successful
candidates will need to be undertaking a higher degree (PhD/MDRes) which
must be completed and awarded by the commencement of the post. The individuals
would write a research programme and would be expected to seek an academic
partner in research, probably from the UCL Institute of Ophthalmology, with
whom the research project will be undertaken jointly. The appointments will be
for four years’ duration.
The training programmes for these lectureships have been selected through
national competition to provide high quality academic training for individuals in
specialist training who can demonstrate that they have outstanding potential for
development as a Clinical Academic in research and/or education. These ST5 level
Academic Clinical Lectureship posts allow the successful candidates to divide their
time 50:50 between clinical training and undertaking research. It is expected that
over the four year appointment the successful candidates will complete their clinical
training on the North Thames Ophthalmology rotation to obtain their CCT,
whilst also spending 50% of their time in both clinical and laboratory based
research under the guidance of their Academic Supervisor.
Please apply online for this position at [Link] where you can download
the job description and person specification.
It is essential that applicants complete the online application form in full.
Closing date for applications: Friday 18 July 2008
Successful candidates are expected to take up their posts by 1st August 2009.
Working Towards Equality of Opportunity
POSITIVE ABOUT DISABLED PEOPLE
[Link]

NIHR Biomedical Research Centre for Ophthalmology

Moorfields Eye Hospital NHS Foundation Trust and
UCL Institute of Ophthalmology
City Road
London EC1V 2PD

Ref: D4 /91

Clinical Lectureship in Ophthalmic Translational Research

The National Institute of Health Research (NIHR) Specialist Biomedical Research Centre
(BMRC) at Moorfields Eye Hospital / UCL Institute of Ophthalmology is one of six new
specialist BMRCs in the UK. The partnership has an outstanding track record of basic
biomedical research, much of which has led to translational programmes and innovations that
have already benefited large numbers of patients in the United Kingdom and around the
world. The juxtaposition of a huge and unique clinical resource at one of the largest and the
longest established eye hospitals in the world, together with one of the largest eye
research institutions with 40 academic staff, has led to a wide range of ground breaking
biomedical research firmly embedded in an appreciation of important clinical problems. The
site is one of the most productive and pre-eminent ophthalmological research sites in the
world. The Moorfields Eye Hospital / UCL Institute of Ophthalmology BMRC focuses on
five research themes: Age-related macular degeneration, Diabetes, Glaucoma, Ocular Surface
Disease, and Paediatric Ophthalmology and Inherited Eye Disease. This is not exclusive for
applicants.

We are seeking to appoint four Clinical Lecturers to posts in 2009 (with 2 further posts to be
advertised in the future) to undertake translational biomedical research in both clinical and
research settings included within the Centre. The successful candidates will need to be
undertaking a higher degree (PhD/MDRes) which must be completed and awarded by the
commencement of the post. The individuals would write a research programme and would be
expected to seek an academic partner in research, probably from the UCL Institute of
Ophthalmology, with whom the research project will be undertaken jointly. The appointments
will be for four years’ duration.

The training programmes for these lectureships have been selected through national
competition to provide high quality academic training for individuals in specialist training
who can demonstrate that they have outstanding potential for development as a Clinical
Academic in research and/or education. These ST5 level Academic Clinical Lectureship posts
allow the successful candidates to divide their time 50:50 between clinical training and
undertaking research. It is expected that over the four year appointment the successful
candidates will complete their clinical training on the North Thames Ophthalmology rotation
to obtain their CCT, whilst also spending 50% of their time in both clinical and laboratory
based research under the guidance of their Academic Supervisor.

Please apply online for this position at [Link] where you can download the job
description and person specification. It is essential that applicants complete the online
application form in full.

Closing date for applications: Friday 18th July 2008

Successful candidates are expected to take up their posts by 1st August 2009.

WORKING TOWARDS EQUALITY OF OPPORTUNITY

Jump to Apply Now

More information
You can view more information about this employer and this vacancy by clicking on any of
the Job Pack Documents or Further Links below. Clicking a link will open a pop-up window
containing the relevant details. You may view, print or download the details from there.
Documents
• Job Description (67 KB)

• Person Specification (54 KB)

• Additional Document (67 KB)

Further Links
• Trust web site

CRB Check
This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as
such it will be necessary for a submission for Disclosure to be made to the Criminal Records
Bureau to check for any previous criminal convictions.
UK Registration
Applicants must have current UK professional registration. For further information please
 MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST &
UCL INSTITUTE OF OPHTHALMOLOGY

JOB DESCRIPTION
UKCRC/MMC NIHR INTEGRATED ACADEMIC TRAINING (IAT)

CLINICAL LECTURER

NIHR BIOMEDICAL RESEARCH CENTRE

Moorfields Eye Hospital – Background Information

MoorfieldsEye Hospital NHS Trust is a teaching hospital managed by a Trust Board
appointed by the Secretary of State. The Hospital is closely associated with the
adjacent UCL Institute of Ophthalmology and this association fosters a unique
mixture of teaching and research.

The Hospital has a 24-Hour Accident and Emergency Department, modern and well
equipped Operating Theatres, an extensive Outpatient Department and a wide range
of clinical and non-clinical support services. Moorfieldsalso has eleven Community
Eye Service Units which provide community based Primary Ophthalmic Care and
Specialist Services. Patients are referred from the surrounding catchment area, but
additionally both the Hospital and Institute provide a nationwide service for
consultation and treatment of rare or complex cases.

Consultant Physicians hold weekly clinics in general medicine and neurology and
there are close links with the National Hospital for Neurology & Neurosurgery
through these consultants. There is a joint Consultant Radiologist who is also on the
staff of the National Hospital, Queen Square.

The Hospital has an Ophthalmology training programme for SpRs / OSTs who are
based within the North Thames Ophthalmology Rotation. SpRs / OSTs are attached
to the Specialist Service Groups for periods of four months at a time.

UCL Institute of Ophthalmology – Background information

The UCL Institute of Ophthalmology is a dedicated eye research centre associated
with Moorfields Eye Hospital, committed to investigating the causes of eye disease
and the development of new therapies. Forty-one academic staff are employed
across twelve Divisions, encompassing Cell Biology, Visual Science, Molecular
Genetics and others. The Institute received a 5* rating in both the last two research
assessment exercises conducted by HEFCE (in 1996 and 2001), and has therefore
received “double 5*” recognition from HEFCE, demonstrating a sustained level of
research excellence.

The National Institute for Health Research’s Biomedical Research Centre for
Ophthalmology is based at MoorfieldsEye Hospital NHS Foundation Trust and the UCL
Institute of Ophthalmology. Established in April 2007, the centre is funded by the
Department of Health via the National Institute for Health Research. The objective of the
Centre is to conduct 'translational research' that is designed to take advances in basic medical
research from the laboratory to the clinic, enabling patients to benefit more quickly from new
scientific breakthroughs. The research of the Centre falls within five major research
“themes”: Age-related Macular Degeneration, Diabetes, Glaucoma, Ocular Surface Disease,
Paediatric Ophthalmology and Inherited Eye Disease.
Our centre is one of 11 biomedical research centres in the UK that were awarded to NHS-
university partnerships having an outstanding international reputation for medical research
and expertise, and experience of translating research into the clinical setting.
For further information please see use the following web links:
[Link]/ioo

[Link]

[Link]/Healthprofessionals/Biomedicalresearchcentre

The Post
This vacant posts are available from 1st August 2009for a period of 4 years.
Applicants will be expected to have completed their Ophthalmology training to a mid
or Higher level (at least 3rd year SpR/OST5) and be in possession of a relevant
Higher degree (eg PhD, MD Res or equivalent).

Over the period of the year it is envisaged that around 50% of the post holder’s time
will be spent on clinical training and 50% on research.

Research duties will include:

1. Full management of patients attending hospital clinics / casualty departments
as required
2. Preparation and upkeep of research material, equipment and laboratory
space
3. Feedback about, and audit of, research process
4. Development of a programme of research that could ultimately result in
publications in high-rating, peer-reviewed academic journals
 5. Seeking grant support
6. Development and maintenance of national and international research links
7. Contribution, where appropriate, to the development of research programmes
in line with the joint site’s research mission

Clinical duties will include:

1. The post holder will be required to attend specified clinics and surgical lists
2. Management of patients presenting during the week.
3. Supervision of junior medical staff in the Service and participation in informal
and formal clinical teaching.
4. There will be opportunities for undertaking research and audit

The clinical duties of this post are to be undertaken in a manner satisfactory to the
Service Director. Clinical Lecturers are responsible to members of the Consultant
and Honorary Consultant Staff at MoorfieldsEye Hospital NHS Foundation Trust and
to the Academic Supervisory Staff at the UCL Institute of Ophthalmology. They may
also expect to work in close association with Fellows, OSTs, as well as members of
various departments within the Institute of Ophthalmologynot directly related to their
research. They are expected to liaise closely with members of the nursing staff
regarding patient management (including those attending the Accident and
Emergency Department); and to co-operate with other professional and technical
staff, including Orthoptists and Optometrists. Clinical Lecturers are expected to
undertake teaching duties in the management of patients (including those attending
the Accident and Emergency Department) with regard to junior and non-training
grade medical staff, orthoptic students and other professional and technical staff in
training. They are expected to take an active part in Audit meetings.

Programme
Clinical Lecturers will attend general and specialist clinics at Moorfields Eye Hospital,
City Road (or elsewhere within the North Thames Ophthalmology rotation) according
to the junior doctors’ 4 month rotations between the specialist services.

Working emergencies and unforeseen circumstances

Clinical Lecturers are expected to perform duties in clinical emergencies and
unforeseen circumstances at the behest of their Service Consultant. They will also
participate in emergency procedures to deal with fires, floods, security risks and the
like as directed by the Chief Executive.

It has been agreed between the profession and the Department of Health that, while
juniors accept that they will perform such duties, additional commitments arising
under this sub-section are exceptional and that junior staff should not be required to
undertake work of this kind for prolonged periods or on a regular basis.

Study and training

Study leave is granted prospectively (on the basis that at least 2 months notice is
given) by the Study Leave Committee, following Consultant approval, and subject to
agreement by the Clinical Management Board.

Main conditions of service

The post is covered by the Terms and Conditions of Service for Hospital Medical and
Dental Staff (England and Wales) and General Whitley Council Conditions of Service
with the exception of paragraph 190 and may be amended from time to time by the
Trust.

Salary
The salary range is between £28,352 to £44,581 per annum plus a London
Weighting of £2,162 per annum.

Annual leave entitlement

Six weeks per year by agreement with the Teaching and Service Directors.

Conditions of appointment
The Clinical Lecturer Person Specification contains information regarding required
qualifications and eligibility. In addition, appointees will have membership of a
Medical Defence Organisation. The required notice period is available on request
from the Personnel Department.

No Smoking Policy
The Hospital operates a no smoking policy and all staff are asked to comply with this
and to promote it at all times.

Facilities
A well stocked library offers comprehensive sections on all aspects of ophthalmology
and is available to all medical staff.

There is a subsidised staff restaurant in addition to a cafeteria and shop run by the
Friends of Moorfields.

Rehabilitation of Offenders Act

Because of the nature of the work for which you are applying, this post is exempt
from the provisions of Section 4 (2) of the Rehabilitation of Offenders Act 1974
(Exemptions) order 1975. Applicants are, therefore, not entitled to withhold
information about convictions which for other purposes are "spent" under the
provisions of the Act, and in the event of employment, any failure to disclose such
convictions could result in dismissal or disciplinary action by the Authority. Any
information given will be completely confidential and will be considered only in
relation to an application for positions to which the order applies.

Applications
Application is via online application at the NHS Jobs Recruitment site at
[Link] Ifyou experience any problems, please contact the Personnel
Department (020 7566 2041 / 2430 / 2043). Descriptions of the clinical training and
service requirements will be available from the Personnel Department once start
dates are finalised, according to the rotational placements for the specialist services.

As attachments cannot be made to the on line application form you will need
to email the following documents to personnel@[Link]. Please
ensure that all emails and documents contain the following:-

a. your name
b. job reference D4 / 91
c. the reference number on your application form which will start with AR

The additional documents you are required to send to the above Personnel
email address are:

• A Research proposal. Applicants should view the BMRC’s website for the list
of research areas and academic supervisors available to Clinical Lecturers.
Applicants are encouraged to contact a prospective supervisor in advance of
submitting an application. The research proposal should outline the research
question the Clinical Lecturer intends to explore, the facilities for which s/he is
 likely to need access (for example, patient cohorts, research equipment), and
the benefits for patients that might arise from the research. The research
proposal should be no longer than 2 pages.
• The name of the proposed research supervisor you have chosen.
• The completed ‘Supplementary Questions For Candidates Applying For A
Clinical Lectureship As Part Of Integrated Academic Training’ form.

[Link]

Please contact Louise Halfhide, Administrator for the NIHR Biomedical Research
Centre for Ophthalmology, with informal enquiries via email:
[Link]@[Link]

Professor Peng Khawis the Director of the NIHR Biomedical Research Centre for
Ophthalmology, and Director of the Clinical Lecturer programme. He may be
contacted via his secretary on 020 7253 3411 ext 2334.
Closing date for receipt of applications is:- Friday 18th July 2008

MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST &

UCL INSTITUTE OF OPHTHALMOLOGY

CLINICAL LECTURER

TRAINING PROGRAMME DESCRIPTION - NIHR BIOMEDICAL RESEARCH

CENTRE, UKCRC/MMC INTEGRATED ACADEMIC TRAINING

Objectives of Academic and Clinical Training:

The objective of the academic training is to allow the trainee to consolidate and build
on their relevant Higher Degree training and develop their research skills to the point
where they can achieve a successful independent research career. The objective of
the clinical training is to achieve the clinical skills necessary within a structured
clinical training programme enabling them to work as a consultant ophthalmologist in
the UK. It is anticipated that most of the candidates for the lectureships will usually
enter at a mid or higher level of training (ie SpR3 / OST 5).

Training support, location, infrastructure and protected time for research and
education:
The Lecturer will have an honorary contract with UCL, which provides full access to
post doctoral courses and lectures, training, laboratory space, libraries and other
facilities, and will have study leave for meetings and courses. It is expected that the
Lecturers will be associated with one of the many major research groups at the UCL
Institute of Ophthalmology and interact with the other researchers. The Lecturers will
have recourse to internal peer review for papers and grant applications before
submission. Research time for Lecturers will be fully protected by doing alternate
clinical and research periods. During the equivalent clinical weeks, there will be a
balanced programme including 3 sessions for education, study and administration as
recommended by the Royal College of Ophthalmologists who have approved this
timetable

Mentoring arrangements for each trainee:

Each trainee will have a named clinical and scientific mentor. This can be the same
person if appropriate. Each Lecturer will have more informal quarterly meetings and
a formal annual clinical and academic review (jointly if there are separate clinical and
academic mentors).

Milestones and assessment:

The academic milestones for the trainees will include progress in their research
programme as delineated during early review meetings, publications in good
journals, and progress in obtaining grant support.

Individual needs of the Lecturer, quality of training, and academic mobility:

The mentoring system with regular reviews should ensure each Lecturer has a
suitable training scheme. This system will monitor the quality of both scientific and
clinical training. The curriculum is in essence broad based but can be tailormadein a
number of ways, as it is for other ophthalmic trainees. If the RITA process identifies a
training need, targeted training would be undertaken in that area - the Specialist
Training Committee would organise this. Each Lecturer will continue rotating through
the four month clinical attachments, doing alternate clinical and academic weeks
until he/she attains a Certificate of Completion of Specialist Training. During this
time, the Lecturer will also be mentored to apply for post-doctoral training support eg.
Clinician Scientist awards from sponsors such as WellcomeTrust and the Medical
Research Council.

Parameters/requirements

• Acquire resources and financial support consistent with a double 5*-rated

institution.
• Develop and ultimately undertake an independent research programme
complementary to the overall research strategy of the Division and the Institute.
• Develop and maintain national and international research links and a high profile
in their field.
• Maintain an output of publications using well-regarded means, such as in high-
rating peer-reviewed academic journals, reputable publishers, and conference
proceedings.
• Contribute their special expertise to the development of research programmes
that meet the mission of the site and to play a significant role in regular research
group meetings.
Ultimately supervise postgraduate students engaged in research, postdoctoral
research workers and research assistants, as appropriate
 MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST &

UCL INSTITUTE OF OPHTHALMOLOGY

NIHR BIOMEDICAL RESEARCH CENTRE

UKCRC/MMC NIHR INTEGRATED ACADEMIC TRAINING (IAT)

Person Specification

Clinical Lecturer
ESSENTIAL DESIRABLE METHODS TO
TEST FIT TO
THESE
CRITERIA
• GMC registration • Other degrees awarded Application form
• MB BS (or equivalent) • Extracurricular activities/ Interview
• MRCOphth / FRCS or achievements relevant to
FRCS (Ed) or equivalent ophthalmology
• Relevant Higher Degree,
PhD or MD Research or
equivalent
• Evidence of achievement of
Foundation competencies
or equivalent, in line with
GMC standards/Good
Medical Practice including:
Good clinical care

Maintaining good medical practice

Good relationships and

communication with patients

Good working relationships with

colleagues
QUALIFICATIONS
Good teaching and training
&
Professional behaviour and
ELIGIBILITY Probity

Delivery of good acute clinical

care

• Evidence of good progress

in clinical training and that
completion of specialty
training may be
accommodated either
 ESSENTIAL DESIRABLE METHODS TO
TEST FIT TO
THESE
CRITERIA
during or after the 4 year
period of the CL award
• Eligibility to work in the UK
• In possession of an • Experience in other Application form
NTN related specialities
CLINICAL
• Wide experience of
EXPERIENCE intraocular surgery,
equivalent to Year 3 of SpR
training / OST5.
• Understanding of the principles of • research
research experience,
presentations, Application form
• Demonstration of understanding
and commitment to academic publications,
career prizes and
• Indication of medium and long- honours
Interview
term career goals • Evidence of
• Demonstration of a keen interest in previous research
grants awarded
the research element of the CL
ACADEMIC/ programme • Evidence of
RESEARCH • Demonstration of understanding of active
participation in
the principles of audit and
audit
research; evidence of participation
in audit
• Demonstration of the potential for
scientific independence and the
ability to lead a research team
• Appropriate
knowledge base
and capacity to
apply sound clinical
judgement Application form
• understanding of
clinical risk
management References
• competent to work
CLINICAL SKILLS without direct supervision
where appropriate
• clear, logical thinking
showing an
analytical/scientific
approach
• good manual dexterity
and hand/eye co-ordination
• up to date and fit to
practise safely
• appropriate level of • demonstrate
clinical knowledge s breadth of
• shows knowledge of experience and Application form
evidence informed practice awareness in and
• shows awareness of outside
own limitations specialty/medicin
Interview
• Demonstration of e
acquisition of the level of • demonstrate
s use of evidence
 ESSENTIAL DESIRABLE METHODS TO
TEST FIT TO
THESE
CRITERIA
knowledge and skills informed practice
necessary for the • Knowledge
achievement of Foundation of the centre
and clinical (matched to the hosting the
KNOWLEDGE entry level) competencies research and how
or equivalent this is best placed
to support the
research,
education and
training needs
• Prizes or
distinctions
• Presentation
of work at a
national or
international
meeting
• Ability to organise • understandin Application form
oneself & own work and g of NHS, clinical
prioritise clinical need governance &
• Capacity to manage resource Interview
time and information constraints;
ORGANISATION & effectively management/fina
ncial awareness;
PLANNING experience of
committee work
• information
technology skills
 ESSENTIAL DESIRABLE METHODS TO
TEST FIT TO
THESE
CRITERIA
• Communication & • the ability to produce
language skills: legible notes
Application form
All applicants to have

demonstrable skills in written

Interview
and spoken English that are

adequate to enable effective

References
communication about

medical topics with patients

and colleagues which could

be demonstrated by one of

the following:

a) that applicants have undertaken

undergraduate medical training in

English; or

b) have the following scores in the

academic lnternational English

Language Testing System (IELTS) –

Overall 7, Speaking 7, Listening 6,

Reading 6, Writing 6.

Ability to build rapport, listen,

persuade, negotiate

• uses a non-judgmental approach

to patients and colleagues
PERSONAL regardless of their sexuality,
SKILLS ethnicity, disability, religious
beliefs or financial status
• Decisiveness/accoun
tability: ability to take
responsibility, show
leadership, make
decisions, exert appropriate
authority, capacity to use
logical/lateral thinking to
solve problems and make
decisions
ESSENTIAL DESIRABLE METHODS TO
TEST FIT TO
THESE
CRITERIA
• Interpersonal skills,
managing others and
team involvement: see
patients as people,
empathise, work co-
operatively with others in
multi-professional teams,
open and non-defensive,
sense of humour, self-
starter, motivated, shows
curiosity, initiative
• Flexibility: able to
change and adapt, respond
to rapidly changing
circumstances
• Resilience: able to
operate under pressure,
demonstrates initiative,
cope with setbacks, self-
aware
• Thoroughness: is
well prepared, shows self-
discipline/commitment, is
punctual and meets
deadlines
• Probity: displays
honesty, integrity. Capacity
to take responsibility for
own actions and
demonstrate a non-
judgemental approach
towards others, aware of
ethical dilemmas
 SUPPLEMENTARY QUESTIONS FOR
CANDIDATES APPLYING FOR A CLINICAL LECTURESHIP AS
PART OF INTEGRATED ACADEMIC TRAINING

Academic Achievement and Professional qualifications

University (ies) attended. Please also indicate the Department or School. Dates

Shortlisted candidates will be required to bring original certificates to the interviews

Degree/Diploma (include BSc, BDS, Awarding Body Date of Qualification
BChD, MBBS, MSc, MB/PhD, PhD,
MD or equivalent) – state class of
degree awarded, where appropriate.

Prizes and other academic Awarding Body Date of Award

distinctions

Key and Relevant Academic Achievements

Prizes or other academic distinctions. Please provide any relevant additional information to that provided above.
Describe your PhD research. Include a brief description of your main findings and their impact and the research
methods you used (up to 750 words).

Please describe any research training that you have received to date, for example, training courses in research
methods (up to 250 words).
Publications (short-listed candidates will be asked to bring copies of all peer-reviewed publications to the
interview).
Presentations/posters at national or international conferences (indicate whether national or
international).

Other Relevant Experience

Please provide brief description of any teaching experience you have had. You may include experience gained
outside of medicine/dentistry.
Please give examples and brief details of experience you have had of management or leadership.

Aims, Career Objectives, and Commitment to a career in Academic Medicine/Dentistry

Please indicate your medium and long-term career goals in relation to an academic career.

If you are successful in gaining a Clinical Lectureship, please describe how you will manage the completion of
your clinical training.

Please explain how the hosting research department will support your research aims and career objectives.
Any further information relevant to an application for a Clinical Lectureship
Please provide any further information that you feel is relevant to this application, in particular, areas that have
not been covered elsewhere. Please state what skills and attributes you will bring to this position and how you
meet the selection criteria.

Academic Referees
Name, job title and address of at least two referees, one of whom should be able to comment on your suitability
for a Clinical Lectureship.
1 2

Telephone Number Telephone Number

Fax Number Fax Number
Email address Email address
Guidance Notes for completion of the “Supplementary Questions for
candidates applying for a Clinical Lectureship as part of Integrated
Academic Training”

These Guidance Notes are for candidates applying for an IAT Clinical Lectureship.
In addition to the application form please ensure that you meet the criteria in the
Person Specification for a Clinical Lectureship and eligibility criteria outlined in
the paper ‘Clinical Lectureships: Entry, Eligibility, and Exit Points in from August
2007’ which can be downloaded from the National Co-ordinating Centre for
Research Capacity Development’s (NCCRCD) website at
[Link]

Academic Achievement and Professional Qualifications

University (ies) attended

Please provide the name of the university or universities that you have attended
with dates where you gained your professional or academic qualifications. For
each, please name the Department or School where you were based for your
study.

Degree/Diplomas

Please provide all the qualifications that you have achieved which you feel are
relevant to your application for a Clinical Lectureship. Where a class or grade was
associated with your qualification, please provide this information. The date and
awarding body of your qualification(s) should also be provided. Please note that
original certificates will be requested at interview.

Prizes or other academic distinctions

Please list any prizes or academic distinctions (maximum of six) which you have
gained and provide the date of award and the awarding body for each.

Key and Relevant Academic Achievement

Prizes and other academic distinctions

This section gives you the opportunity to provide further detail about the prizes
or distinctions you have achieved. Please select those that are relevant to your
application for a Clinical Lectureship and briefly describe what you did in order to
be recognised with a prize or distinction.

Describe your PhD research

This section gives you the opportunity to describe the research you completed
for your PhD. Please include a brief description of your main findings and the
impact these have had. Examples of impact could include:-

• Contribution of research to practice, diagnosis, treatment or management

of patients;
• Contribution of research to the understanding of a disease process;
• Changes to a service (e.g. a referral pathway); and
• Translation of a research finding or development into clinical practice (e.g.
a diagnostic tool)

Please also give details of the research methods that you used. Please do not
exceed the 750 word limit.

One other significant research project

This section provides you with the opportunity to give details about one other
significant research project, other than your PhD, that you have been involved in.
You only have 250 words, but please give brief details about the project, the
methods you used and you exact role in and contribution to the project overall.

Publications

Please list all your publications. Please note that short-listed candidates will be
required to provide copies of their peer-reviewed publications at interview.

Presentations/posters
Please provide details of any posters or presentations you have given at both
national and international conferences. Please make it clear which are national
and which are international.

Other Relevant Experience

Teaching experience

Please describe any experience you have of teaching and indicate where this is
relevant to research. You may also include examples outside of
medicine/dentistry.

Management or leadership

Please give examples and brief details of the experience you have had of
developing your management or leadership skills.

Aims, Career Objectives and Commitment to a Career in Academic

Medicine/Dentistry

Medium and long-term career goals

Please indicate your medium and long-term goals in relation to academic

medicine/dentistry. You might wish to say what you are aiming to be doing in 5
and 10 years time.

Managing completion of clinical training

Please use this section to describe how you will manage the completion of your
clinical training alongside your academic development. Please provide a
timetable of your plans.

Support from Host Department

Please explain how the host department offering the Clinical Lectureship you
have chosen will support your research aims and career objectives.

Any further information

Please use this section to provide information which might support your
application that has not been covered elsewhere on the form. Please describe
the skills and attributes that you feel you have which make you a suitable
candidate for a Clinical Lectureship.
[Link]

Clinical Research Associates in Vision Research

(MRCOphth or equivalent required)

The National Institute for Health Research (NIHR) Specialist Biomedical Research Centre (BMRC)
for Ophthalmology at Moorfields Eye Hospital NHS Foundation Trust / UCL Institute of
Ophthalmology is seeking to accelerate the application of clinical and basic research in the
treatment of blinding eye diseases. We have vacancies for three motivated individuals who have
achieved MRCOphth or equivalent residency training recognised by the GMC to join us as Clinical
Research Associates within the research themes of Diabetes, Ocular Surface Disease or
Paediatric/Inherited Eye Diseases.
Applicants must have achieved the MRCOphth or equivalent overseas qualification; be able to
perform a competent clinical ophthalmological examination; be committed to high quality research
and be able to perform technically and intellectually demanding experiments independently.
Previous research experience is desirable, as is a BSc (or overseas equivalent) qualification.
The Clinical Research Associates will have considerable input into research project direction; work
collaboratively with colleagues; organise project data; present research at national and
international meetings; prepare project results for publication; undertake specific technical/clinical
duties relevant to individual projects.
Appointment is likely to be made at the base of the appropriate clinical research scale, either CL7
(£29,580-£37,510) or CL8 (£37,510-£42,813) plus London Allowance at £2,649. The post-holders
will be based at UCL Institute of Ophthalmology and Moorfields Eye Hospital NHS Foundation Trust.
Recruitment will be made for 24 to 36 months, in the first instance. Please see individual job
descriptions for specific terms.
Please click for:
Job description for Inherited Eye Disease
Job description for Ocular Surface Disease
Job description for Diabetic Retinopathy
and an application form or via email at : education-ioo@[Link]. Please quote
reference number: 127265-7.
Completed applications should be returned by post (as signed copies are required) to the
Personnel Office, UCL Institute of Ophthalmology, 11-43 Bath Street, London EC1V 9EL,
U.K. In the interests of economy only those candidates who are called for interview will
be notified of the outcome of their application. Any applicant who is not an EU or UK
resident, should be aware when applying that any offer will be dependent on the
Institute being able to obtain a valid work permit on his/her behalf.'
Closing date for the receipt of applications: 25 July 2008.
UCL Taking Action for Equality
Pursuing Excellence in Education and Research

UCL INSTITUTE OF OPHTHALMOLOGY

 Ocular Surface Diseases

Clinical Research Associate

REF: 127266
UNIVERSITY COLLEGE LONDON (UCL)

INTRODUCTION

UCL is one of the UK’s premier universities. It is a world-class research and

teaching institution based in Londonwhose staff and former students have included
19 Nobel Prize winners. Founded in 1826, it was the only university in Englandat
that time which admitted students regardless of race or religion. UCL was also the
first to admit women on equal terms with men. Today UCL is a friendly university in
which to work and study and it continues to thrive on the diversity and creativity of its
community.
UCL is in practice a university in its own right, although constitutionally a college
within the federal University of London. With an annual turnover exceeding £485
million, it is financially and managerially independent of the University of London.

The UCL community

UCL has over 18,000 students from over 140 countries and employs over 8,000 staff,
including 3,800 plus academic staff. In total, there are 70 Academic Departments and
Institutes whose activities span the following: arts and humanities, social and historical
sciences, law, architecture and the built environment, engineering, mathematical and
physical sciences, life and clinical sciences, and medicine. UCL’s academic and research
staff are a truly international community with more than a quarter coming from 84 countries
outside the UK.

UCL’s annual turnover exceeded £485m in the latest financial year. Over 12,000
undergraduates and 7,000 graduate students study at UCL, of whom over 25%
come from 130 countries outside the UK. UCL offers 275 undergraduate
programmes and more than 220 taught postgraduate programmes as well as the
opportunity to carry out postgraduate research in all of its subjects.

UCL has the highest number of professors of any university in the UK, an academic
community including 35 Fellows of the Royal Society, 27 Fellows of the British Academy, 13
Fellows of the Royal Academy of Engineering and 75 Fellows of the Academy of Medical
Sciences. Nobel Prizes have been awarded to 18 academic staff and graduates.

Quality of UCL’s teaching and research

Two measures of the current quality of UCL’s teaching and research are the results
of the external teaching quality assessment reviews and the periodic Research
Assessment Exercise (RAE).

During the teaching quality reviews conducted in the period 1993-2001, 75% of all
reviews of UCL Departments resulted in ratings of ‘excellent’ (22+ points out of 24).
Of these, four Departments received the maximum 24 points.

In the 2001 RAE, 60 UCL Departments achieved top ratings of 5* and 5: of these, 15
Departments have since been classified by the Higher Education Funding Council for
England (HEFCE) as 'best 5*' for HEFCE research funding purposes - that is,
departments which either received the 5* rating both in 2001 and in the previous
RAE in 1996 or which improved their 1996 rating to 5* in 2001 while maintaining or
increasing numbers of research active staff. These 'best 5*' departments span the
full range of UCL’s disciplines.

Another measure of UCL’s research excellence has been its success in bidding for
external competitive funds from the Joint Infrastructure Fund (JIF) and the Science
Research Investment Fund (SRIF). With the addition of required matching funds, JIF
and SRIF are allowing UCL to invest more than £250 million into state-of-the-art
infrastructure for cutting-edge research and teaching programmes.
UCL is consistently rated among the top four universities in the UK (together with
Cambridge, Imperial College and Oxford) and in the 20 best universities in the world.

UCL Institute of Ophthalmology

The Institute of Ophthalmology is one of a number of specialised biomedical

research centres within UCL and is, together with Moorfields Eye Hospital, world’s
leading centres for eye health, vision research and training.

UCL Institute of Ophthalmology conducts cutting-edge science, attracting research workers

of the highest international calibre. In recognition of our international standing, the Higher
Education Funding Council for England (HEFCE) has awarded us the highest possible rating
in the last three Research Assessment Exercises; we hold a "5**".

The researcher of tomorrow is critical to our goal of improving sight. To this end, we are
involved in graduate training of research students (MD, MPhil, PhD) and our contributions to
UCL undergraduate and taught graduate teaching are increasing year by year.

The Institute is committed to a multi-disciplinary research portfolio that

furthers an understanding of the eye and visual system linked with clinical
investigations targeted to specific problems in the prevention and treatment of
eye disease. The combination of the Institute’s research resource with the
resources of Moorfields Eye Hospital, which has the largest ophthalmic patient
population in the Western World, opens the way for advances at the forefront
of vision research and provides an unparalleled setting for research and
training in ophthalmology.

IT facilities are available to all staff and the Institute has modern, well-
equipped laboratories which cater for academic staff whose specialities fall
within the remit of four Research Departments:

• Cell Biology
• Genetics
• Ocular Biology and Therapeutics
• Visual Neuroscience

The Institute employs 170 staff, has a budget of £11m and is locate next to the City of
London’s main financial district near Old Street Underground station, a short distance from
Liverpool Street Rail station.

To find out more about our research and teaching visit [Link]
Background

The National Institute for Health Research’s Biomedical Research Centre for
Ophthalmology is based at MoorfieldsEye Hospital NHS Foundation Trust and the
UCL Institute of Ophthalmology. Established in April 2007, the Centre is funded by
the Department of Health via the National Institute for Health Research. The
objective of the Centre is to conduct 'translational research' that is designed to take
advances in basic medical research from the laboratory to the clinic, enabling
patients to benefit more quickly from new scientific breakthroughs. The research of
the Centre falls within five major research “themes”: Age-related Macular
Degeneration, Diabetes, Glaucoma, Ocular Surface Disease, Paediatric
Ophthalmology and Inherited Eye Disease.
Our centre is one of 11 Biomedical Research Centres in the UK that were awarded to NHS-
university partnerships having an outstanding international reputation for medical research
and expertise, and experience of translating research into the clinical setting. For further
information, please see [Link]/bmrc

Moorfields Eye Hospital NHS Foundation Trust

MoorfieldsEye Hospital NHS Foundation Trust is a teaching hospital managed by a Trust
Board appointed by the Secretary of State. The Hospital is closely associated with the
adjacent UCL Institute of Ophthalmology and this association fosters a unique mixture of
teaching and research.

The Hospital has a 24-Hour Accident and Emergency Department, modern and well
equipped Operating Theatres, an extensive Outpatient Department and a wide range of
clinical and non-clinical support services. Moorfieldsalso has eleven Community Eye
Service Units which provide community based Primary Ophthalmic Care and Specialist
Services. Patients are referred from the surrounding catchment area, but additionally both
the Hospital and Institute provide a nationwide service for consultation and treatment of rare
or complex cases. The Hospital has an Ophthalmology training programme for SpRs/ OSTs
who are based within the North Thames Ophthalmology Rotation. For further information,
please see [Link]

The Ocular Surface Diseases Research Theme: The objective of this research theme is to
reduce the impact of disorders of the cornea and conjunctiva in patients and the population.
We have prioritised the following two areas of translational research within the Ocular
Surface Diseases theme and the successful applicant will work on one of these projects.
The post-holder is encouraged to consider enrolling for a higher degree (eg. PhD). Training
in all techniques will be given.

Limbal Stem Cell Transplantation project

Limbal epithelial stem cell (LESC) failure, resulting from injury or disease, results in
significant patient discomfort and loss of vision. The Cells for Sight Transplantation Unit was
established in 2002 to translate laboratory research into successful treatment for LESC
failure and is based at the Institute of Ophthalmology, directed by [Link] Daniels and
[Link] Tuft.

The research programme is centred on improving outcomes in the LESC therapy currently
undertaken on patients in Moorfields and developing novel cell-based therapies to treat
ocular surface disease (see Stem Cells 2007;25:1402 and Surv Ophthalmol 2007;52:483). It
includes the following projects,
(i) Identification of novel localised stem cell-rich areas within the limbus which will facilitate
targeting of biopsies for optimal autologous LESC expansion in culture.

(ii) Identify alternative sources of mucous membrane suitable for ocular surface
reconstruction using autologous tissue.
(iii) Attempts to control the LESC phenotype by manipulating gene expression in stem cells.
The long-term goal is to develop gene-based approaches for LESC failure.

Corneal Transplantation project

One of the major problems in corneal disease are patients who require corneal
transplantation to restore vision, but in whom the likelihood of successful surgery is very
poor. Over the next 3-5 years, the research programme on corneal transplantation will have
a dual approach of prevention of corneal transplant rejection by the host immune system
and augmentation of transplant endothelial function post-grafting by ex vivo genetic
modification of donor cornea pre-graft. The research will be undertaken at the Department of
Molecular Genetics, Institute of Ophthalmology and Moorfields Lions Eye Bank, directed by
Professor Robin Ali and Mr Frank Larkin.

The research will build on earlier pilot studies of cDNA transfer to donor corneas to induce
endothelial cell replication and prevent allogeneic rejection (Invest Ophthalmol Vis Sci
2005;46:3597 and Eur J Immunol 2006;36:690). Further investigation is required to bring this
approach to the stage that it can be translated into clinical transplantation and we plan to
investigate the efficacy and safety of new technologies (Nature Med 2006;12:348) for gene
transfer. The expertise in vector development in the laboratory of Professor Ali will be
essential in developing this aspect of the project.

The recently constructed Moorfields Lions Eye Bank will be a platform to allow evaluation of
these interventions and, as for the Cells for Sight facility described above, provide proven
new interventions to improve transplant outcomes in patients.

The Post

For either project, the post-holder will be required to,

• have considerable input into project direction and experimental design

• work collaboratively with other members of the team and clinical colleagues
• organise project data
• participate in laboratory meetings and journal clubs
• achieve goals, agreed in discussions with the principal investigators, independently
and efficiently
 • present the results of the project in national and international meetings
• prepare the results of the project for publication
• perform any other duties within the scope, spirit and purpose of the post, the title of
the post and its grading as requested by the supervisor and head of division.
• the post-holder will gain experience in the clinical management of patients with ocular
surface diseases.

Person Specification

Knowledge – including Qualifications

Medical qualifications: MBBS, MRCOphth

Skills

• Must be able to perform basic ophthalmic examination competently.

• Good basic IT skills.

Experience

• Should have experience of working in a multi-disciplinary environment and a multi-

disciplinary team working.
• Should ideally have some experience of previous clinical or laboratory research.

Personal Qualities

• Commitment to high quality research.

• Ability to work collaboratively and as part of a team.
• Commitment to maintaining a good knowledge of the published literature in
the relevant fields.
• Have an agreeable manner.
• Commitment to UCL’s policy of equal opportunity and the ability to work
harmoniously with colleagues and students of all cultures and backgrounds.
 4. Person Specification

Requirements Criteria Assesse

E / D* d
A / I*
1. Education, Qualifications and Training
MRCOphth or equivalent overseas Ophthalmology E A
qualification
BSc or equivalent overseas qualification D A
2. Skills, Ability
Ability to perform a competent clinical ophthalmological E A/I
examination

Good IT and computer skills E A/I

3. Experience
General ophthalmology E A/I
Previous research experience in a clinical or laboratory D A/I
environment
Experience of working in a multi-disciplinary environment E A/I
4. Knowledge
5. Personal qualities
Commitment to high quality research. E I

Ability to work collaboratively and as part of a team. E

Ability to perform technically and intellectually demanding E I

experiments independently
Commitment to maintaining a good knowledge of the E I
published literature in the relevant fields
He/she will be required to have an agreeable manner E I
Commitment to UCL’s policy of equal opportunity and the E I
ability to work harmoniously with colleagues and students of
all cultures and backgrounds

* E = Essential; D = Desirable; A = Application; I = Interview

5. Conditions of Appointment

Appointment

The post is graded as CL7 or CL8. CL7 starts at £29,580 and ends at £37,510 plus
discretionary points and CL8 starts at £37,510 plus and ends at £42,813 plus discretionary
points. London Allowance is currently £2,649 and is paid in addition to basic salary.
Although consideration will be given to a candidate’s skills, experience and knowledge,
appointment will normally be made at the base of this range. Cost of living pay awards are
negotiated nationally and are normally effective from 1st August each year.

To be considered for CL8,in addition to the above criteria, the candidate would be
expected to have research experience with evidence of achievement (such as published
research papers) in a subject area relevant to the post. In addition, the candidate would be
expected to demonstrate potential in some or all of the following areas:-

• leading a small team of researchers

• being invited to give papers at conferences
• serving on peer review Committee.

Duration

The post will be offered for 36 months, in the first instance.

Location

Employees of the Institute normally work at the Institute's main location in 11 - 43 Bath
Street, London EC1V 9EL. Some members of staff may also be located within Moorfields
Eye Hospital, City Road, London EC1V 2PD. The Institute reserves the right to re-locate
staff between the above two organisations. Occasionally, staff may be required to work at
other locations; this will be subject to discussion between the member of staff and the
Institute.

Probation
Appointments are subject to receipt of satisfactory references and a probationary period of 9
months.

Hours of Work

Full time hours are 36½ hours per week and times of work are as determined by the Institute
Director, normally between 8:00 am and 6.00pm Monday to Friday.

Holidays

Annual leave is 27 working days for a full time member of staff.

UCL also closes for a period at Christmas and Easter, at which times staff benefit from a
total of 6 ‘closure days’ in addition to Bank Holidays.

Pension

If the post holder is not already a member of the NHS pension scheme he/she will be
eligible to join the Universities Superannuation Scheme, which is a final salary
scheme with a current employee contribution rate of 6.35% and an employer
contribution rate of 14% of salary.

Season Ticket Loans

A season ticket loan is available to staff who have successfully completed their probationary
period with the facility to repay through a monthly deduction from salary.
Equal Opportunities

Our policy includes the provision that in recruitment, the only consideration must be that the
individual meets or is likely to meet the genuine requirements of the job. No one will be
discriminated against on the basis of gender, age, race, colour, ethnic origin, physical
disability, marital status, sexual orientation, caring or parental responsibilities, or belief in any
matters including religion and politics.

Informal Enquiries

Informal discussion with the BMRC Administration or appropriate Theme Leader (Mr Frank
Larkin) or associate consultant specialist (Mr Stephen Tuft) can be arranged through Ms
Louise Halfhide at [Link]@[Link] or phone 020 7253 3411,
extension 4657.

For further information about the UCL Institute of Ophthalmology, please visit our website at
[Link]

Details of how to apply for the post

Applications should be either:

1. CV plus the Application for Employment form found at

[Link]
ction_I.doc and the Equal Opportunities Classification form; or

2. UCL Standard Application Form found at:

[Link]

Applications must be accompanied by a supporting letter which should include:

• Job reference 127266

 • Whether we may approach one or all of your referees prior to interview.
Please note that we require details of at least two referees (to include
your current/most recent employer) together with their full postal address,
telephone number and email details. Relatives may not be used as
referees.

• Whether you require permission / a work permit to take up employment

in the UK.

• If employed, how many days (and how many periods) of sick leave you
have had over the last 12 months (provide additional information if you
feel this would be useful).

Applications should be sent to the address below. All applications must be received before
17:00hrs on the closing date. Please send 4 copies of your documentation to:

The Personnel Officer

UCL Institute for Ophthalmology

Fax: +44 (0) 20 7915 1039

Closing date for applications is 25 July 2008.

Closing date for applications: Monday 25th July 2008

We particularly welcome female applicants and

those from an ethnic minority, as they are under-
represented within UCL at these levels. This is in
line with section 48 of the Sex Discrimination Act
and section 38 of the Race Relations Act.
Unfortunately we cannot write to applicants who are not shortlisted. Consequently, if you

have not heard from the Institute of Ophthalmology within four weeks of the closing date,

please assume that you have not been shortlisted. We hope that this does not discourage

you from making further applications in the future.