Albumin
3.2 - 5 g/dl
Alkaline phosphatase
(Adults: 25-60)
33 - 131 IU/L
Adults > 61 yo:
51 - 153 IU/L
Ammonia
20 - 70 mcg/dl
Bilirubin, direct
0 - 0.3 mg/dl
Bilirubin, total
0.1 - 1.2 mg/dl
Blood Gases
Arterial
pH
7.35 - 7.45
Venous
7.32 - 7.42
pCO2
35 - 45
38 - 52
pO2
70 - 100
28 - 48
HCO3
19 - 25
19 - 25
O2 Sat %
90 - 95
40 - 70
BUN
7 - 20 mg/dl
Complete blood count (CBC) Adults
Male
Female
Hemoglobin (g/dl)
13.5 - 16.5
12.0 - 15.0
Hematocrit (%)
41 - 50
36 - 44
RBC's ( x 106 /ml)
4.5 - 5.5
4.0 - 4.9
RDW (RBC distribution width) < 14.5
MCV
80 - 100
MCH
26 - 34
MCHC %
31 - 37
Platelet count
100,000 to 450,000
Creatine kinase (CK) isoenzymes
CK-BB
0%
CK-MB (cardiac)
0 - 3.9%
CK-MM
96 - 100%
Creatine phosphokinase
(CPK)
8 - 150 IU/L
Creatinine (mg/dl)
0.5 - 1.4
Electrolytes
[Link]
Calcium
8.8 - 10.3 mg/dL
Calcium, ionized
2.24 - 2.46 meq/L
Chloride
95 - 107 mEq/L
Magnesium
1.6 - 2.4 mEq/L
Phosphate
2.5 - 4.5 mg/dL
Potassium
3.5 - 5.2 mEq/L
Sodium
135 - 147 mEq/L
Other
Ferritin (ng/ml)
13 - 300
Folate (ng/dl)
3.6 - 20
Glucose, fasting (mg/dl)
60 - 110
Glucose (2 hours
postprandial) (mg/dl)
Up to 140
Hemoglobin A1c
<6% of total Hb
AACE Guidelines (2011)
Hemoglobin A1c, % (as a screening test)
5.4 - Normal
------------------------5.5-6.4 - High risk/prediabetes; requires
screening by glucose criteria
------------------------6.5 -Diabetes, confirmed by repeating the
test on a different day
=================
In general, therapy should target a A1C level
of 6.5% or less for most nonpregnant adults.
Iron (mcg/dl)
65 - 150
Lactic acid (meq/L)
0.7 - 2.1
LDH (lactic dehydrogenase)
56 - 194 IU/L
Lipoproteins and triglycerides
Cholesterol, total
< 200 mg/dl
HDL cholesterol
35 mg/dL. Negative risk factor:
mg/dL
LDL cholesterol
65 - 180 mg/dl
Triglycerides
Normal: < 150 mg/dL.
Borderline-high: 150 to 199 mg/dL
High: 200 to 499 mg/dL
Very High: >499 mg/dL
60
[Link]
Osmolality
289 - 308 mOsm/kg
SGOT (AST)
< 35 IU/L (20-48)
SGPT (ALT)
<35 IU/L
Male: 300 to 1000 ng/dL
Female: < 62 ng/dL
Testosterone - total(serum)
ALT:
Male:
14-15 yr: 33-585 ng/dL
16-17 yr: 185-886 ng/dL
18-39 yr: 400-1080 ng/dL
40-59 yr: 350-890 ng/dL
> 60 yr: 350-720 ng/dL
Tanner Stage IV: 165-854 ng/dL
Tanner Stage V: 194-783 ng/dL
Thyroid Function tests
Thyroid Function Testing
Thyroid Function
Test
Measurement
Normal Range
Total T4 (TT4)
bound and free T4
4.5 -11.5 ug/dL
Free T4 (FT4)
free T4
0.8 -2.8 ng/dL
Free T4 Index
(FT4I)
estimate of free T4
FT4I = TT4 x RT3U
1.0 -4.3 U
Total T3 (TT3)
bound and free T3
75 -200 ng/dL
Resin T3 Uptake
(RT3U)
binding capacity of
TBG
25 -35%
TRH
TRH
5 -25 mIu/mL
TSH
TSH
0.5 - 4.70 IU/mL
American Association of Clinical
Endocrinologists guidelines
changed their normal range for
TSH to
0.3 - 3.04 mIU/L.
Thyroglobulin
Thyroglobulin
5-25 ng/mL
Radioactive Iodine Distribution of
5 hr 5 to 15%
Uptake (RAIU)
radiolabeled iodine in 24 hr 15 to 35%
the thyroid
Notes:
Free T4 - much more useful then total T4 (e.g. interested in unbound or
active form). Total T4 not commonly measured. Greatly affected by TBG.
[Link]
Free T4 index: indirect measure of free T4. Corrects for high/low values of
TBG.
Total T3: not as useful as free T3, however, may be useful in locating
problems with TBG, or if looking for problems with peripheral conversion of
T4 to T3.
Resin T3 Uptake: if low, then TBG binding capacity is high. Opposite if high.
TSH: best measure to determine thyroid function.
Thyroglobulin: nonspecific test that is elevated when the thyroid gland is
inflamed or enlarged.
Free T3
2.3-4.2 pg/ml
Total iron binding capacity
(TIBC)
250 - 420 mcg/dl
Transferrin
> 200 mg/dl
Uric acid
(male)
2.0 - 8.0 mg/dl
(female)
2.0 - 7.5 mg/dl
WBC + differential
WBC (cells/ml)
4,500 - 10,000
Segmented neutrophils
54 - 62%
Band forms
3 - 5% (above 8% indicates left shift)
Basophils
0 - 1 (0 - 0.75%)
Eosinophils
0 - 3 (1 - 3%)
lymphocytes
24 - 44 (25 - 33%)
Monocytes
3 - 6 (3 - 7%)
Absolute Neutrophil Count (ANC) - Oncology
Equations:
(1) Segs and bands reported as a percentage:
WBC * ((segs / 100) + (bands / 100))
(2) Segs and bands reported in total numbers:
WBC * (segs + bands)
Neutrophils (aka polymorphonuclear cells, PMNs, granulocytes, segmented
neutrophils, or segs) fight against infection and represent a subset of the
white blood count. Neutropenia by definition is an ANC below 1800/mm3
(some sources use a lower value).
Absolute neutrophil count (ANC) of 1000-1800:
Most patients will be given chemotherapy in this range.
Risk of infection is considered low.
Mild neutropenia - Absolute neutrophil count (ANC) of 500-1000:
[Link]
Carries with it a moderate risk of infection.
Absolute neutrophil count (ANC) of less than 500:
Severe neutropenia - high risk of infection. Remember that a reduced WBC
is known as leukopenia.
The WBC consists of the following (differential):
Lymphocytes: 20-40%
Neutrophils: 50-60%
Basophils: 0.5-2%
Eosinophils: 1-4%
Monocytes: 2-9% (average: 4%).
ANC = Total WBC x (% "Segs" + % "Bands")
Equivalent to: WBC x ((Segs/100) + (Bands/100))
The ANC refers to the total number of neutrophil granulocytes present in the
blood.
Normal value: 1500 cells/mm3.
Mild neutropenia: 1000 - <1500/mm3.
Moderate neutropenia: 500 - <1000/mm3.
Severe neutropenia: < 500/mm3.
Reference:
Ayalew Tefferi, MD, ed. Primary Hematology. Totowa, NJ: Humana Press,
2001
[Link]
