Course Code: GBE 206
Level: Undergraduate
Course Title: MOLECULAR BIOLOGY II
Year: II
Semester: IV
Status: Mandatory
ECTS Credits: 5
COURSE DESCRIPTION
The course covers advanced topics on molecules, energy, and biosynthesis,
macromolecules (structure, shape, and information), how cells are studied, protein
function, basic genetic mechanisms, recombinant DNA technology, and control of gene
expression, etc.
COURSE OBJECTIVES
Students will move beyond their introductory textbooks towards a deeper understanding of
modern molecular biology.
COURSECONTENTS
Chromatin structure and function
Molecular mechanisms of DNA replication, mutability and repair of DNA
RNA polymerase dynamics
Regulation of gene expression by different types of RNA
Homologous recombination
Site specific recombination and transposition of DNA
Molecular mechanisms of transcription, RNA splicing
Molecular mechanisms of translation, the genetic code
Gene regulation in prokaryotes
Gene regulation in eukaryotes
Gene regulation during development
Genomics and Systems Biology
Techniques in Molecular Biology
Model Organisms
TEACHING/ASSESSMENT
Description
Teaching Methods
Interactive
Discussions and group works
Tutorials and Labs
Description (%)
Student Assessment Methods
Quizzes
Homework
Project
MidtermExamination
Final Examination
Lab
Learning Outcomes
Language of Instruction
(5%)
(10%)
20
40
25
Actively participate in courses and begin to take responsibility for learning.
Begin to work effectively as part of a team, developing interpersonal, organisational
and problem-solving skills with in a managed environment, exercising some personal
responsibility.
Present information in oral, written, and graphic forms in order to communicate
effectively with peers and tutors.
English
Textbook(s)
10%
10%
20%
20%
40%
25%
Alberts, B., Johnson, A, Lewis, J., Raff, M., Roberts, K., & Walter, P. (2007).
Molecular biology of the cell, 5th ed. New York: Garland Science.
Krebs, J.E, Goldstein, E.S., & Kilpatrick, K.S. (2011). Lewines Gene X. Jones and
Bartlett Publishers, Sudbury, MA.
Karp, G. (2013). Cell and Molecular Biology: Concepts and Experiments, 7th ed.
Hoboken: Wiley.
ECTS (ALLOCATED BASED ON STUDENT) WORKLOAD
Activities
Quanti
ty
Duration
Total Work Load
Lecture (14 weeks x Lecture hours per week)
14
28
Laboratory / Practice (14 weeks x Laboratory / Practice hours per week)
14
28
Midterm Examination (1 week)
Final Examination (1 week)
Preparation for Midterm Examination
14
14
Preparation for Final Examination
15
15
Assignment / Homework / Project
18
18
Seminar / Presentation
18
18
Total Workload
ECTS Credit (Total Workload / 25)
125
5