Human Reproduction — Question Paper Page 1
HUMAN REPRODUCTION
CBSE Class 12 | Biology | Very Important Question Paper
Name: _______________________________ Time Allowed: 2 Hours
Class: 12 Section: _______ Maximum Marks: 50
General Instructions
1 This question paper contains six sections — A, B, C, D, E and F.
2 Section A: Q1–10 are Multiple Choice Questions (1 mark each).
3 Section B: Q11–15 are Fill in the Blanks (1 mark each).
4 Section C: Q16–20 are Assertion–Reason questions (1 mark each).
5 Section D: Q21–25 are Short Answer questions (2 marks each).
6 Section E: Q26–28 are Long Answer questions (5 marks each).
7 Section F: Q29 is a Diagram-based question (5 marks).
8 There is no overall choice. However, an internal choice has been provided in one question of 5 marks.
9 Draw neat, labelled diagrams wherever required.
SECTION A — Multiple Choice Questions
(1 mark each)
Q1. Spermatogenesis is initiated due to a significant increase in the level of: (1)
(a) Luteinising Hormone (LH)
(b) Follicle Stimulating Hormone (FSH)
(c) Prolactin
(d) Oxytocin
Q2. Leydig cells, present in the interstitial spaces of the testis, synthesise and secrete: (1)
(a) Androgens
(b) Relaxin
(c) Estrogens only
(d) Inhibin
Q3. The finger-like projections at the edge of the infundibulum that help collect the ovum after ovulation
are called: (1)
(a) Cilia
(b) Fimbriae
(c) Villi
(d) Rugae
Q4. The hormone mainly responsible for inducing strong uterine contractions during parturition is: (1)
(a) Progesterone
(b) Relaxin
(c) Oxytocin
(d) Estrogen
Q5. The site where fertilisation normally occurs in the human female reproductive tract is the: (1)
(a) Uterus
(b) Cervix
(c) Ampullary-isthmic junction of the fallopian tube
(d) Vagina
CBSE Class 12 Biology | Chapter 2: Human Reproduction
Human Reproduction — Question Paper Page 2
Q6. Colostrum, secreted during the initial days of lactation, is particularly rich in: (1)
(a) Fats
(b) IgA antibodies
(c) Lactose
(d) Iron
Q7. The membrane that must be penetrated by a sperm to fertilise the ovum is the: (1)
(a) Zona pellucida
(b) Vitelline membrane
(c) Corona radiata only
(d) Chorion
Q8. The phase of the menstrual cycle during which the ruptured follicle transforms into the corpus luteum
is the: (1)
(a) Menstrual phase
(b) Follicular phase
(c) Ovulatory phase
(d) Luteal phase
Q9. Sertoli cells in the seminiferous tubules are under the regulation of the pituitary hormone: (1)
(a) LH
(b) FSH
(c) hCG
(d) Prolactin
Q10. Human Chorionic Gonadotropin (hCG), which forms the basis of most pregnancy tests, is secreted
by the: (1)
(a) Corpus luteum
(b) Developing embryo/placenta
(c) Anterior pituitary
(d) Hypothalamus
SECTION B — Fill in the Blanks
(1 mark each)
Q11. The membrane covering the ovum that must be penetrated by the sperm during fertilisation is called
the __________. (1)
Q12. Testes are situated outside the abdominal cavity, within a pouch called the __________. (1)
Q13. The inner cell mass of the blastocyst that goes on to form the embryo is called the __________. (1)
Q14. Human placenta is of the __________ type, as maternal blood comes in direct contact with the
chorionic villi. (1)
Q15. The sudden surge of __________ around the mid-cycle leads to rupture of the Graafian follicle and
release of the ovum. (1)
SECTION C — Assertion & Reason
For Q16 to Q20, a statement of Assertion (A) is followed by a statement of Reason (R). Choose the correct option: (a)
Both A and R are true, and R is the correct explanation of A (b) Both A and R are true, but R is NOT the correct
explanation of A (c) A is true, but R is false (d) A is false, but R is true (1 mark each)
CBSE Class 12 Biology | Chapter 2: Human Reproduction
Human Reproduction — Question Paper Page 3
Q16. (1)
Assertion (A): Menstruation occurs due to sloughing off of the endometrium in the absence of
fertilisation.
Reason (R): A sharp decline in the levels of progesterone triggers the breakdown of the endometrial
lining.
Q17. (1)
Assertion (A): Sertoli cells present in the seminiferous tubules are also known as nurse cells.
Reason (R): Sertoli cells synthesise and secrete androgens under the stimulation of LH.
Q18. (1)
Assertion (A): Polyspermy, the entry of more than one sperm into the ovum, is normally prevented during
fertilisation.
Reason (R): The cortical reaction releases granule contents that alter the zona pellucida, blocking the
entry of additional sperms.
Q19. (1)
Assertion (A): Progesterone levels decline steadily throughout human pregnancy.
Reason (R): Human Chorionic Gonadotropin (hCG) maintains the corpus luteum, which continues to
secrete progesterone until the placenta takes over.
Q20. (1)
Assertion (A): Oxytocin is administered clinically (as Pitocin) to induce labour in certain pregnancies.
Reason (R): Oxytocin acts on the uterine musculature to bring about strong contractions that assist in
expulsion of the foetus.
SECTION D — Short Answer Questions
(2 marks each)
Q21. Differentiate between spermatogenesis and oogenesis (any two points). (2)
Q22. Why does menstruation not occur during pregnancy? (2)
Q23. What is the role of Sertoli cells in the seminiferous tubules? (2)
Q24. Mention any two important functions of the human placenta. (2)
Q25. What is colostrum? State its significance for the newborn. (2)
SECTION E — Long Answer Questions
(5 marks each)
Q26. Describe the hormonal regulation of the human menstrual cycle with reference to the follicular,
ovulatory and luteal phases. (5)
Q27. Describe the process of spermatogenesis in humans, including the role of the hormones involved.
(5)
Q28. Trace the sequence of events from fertilisation to implantation in the human female reproductive
tract. (5)
SECTION F — Diagram-Based Question
(5 marks)
CBSE Class 12 Biology | Chapter 2: Human Reproduction
Human Reproduction — Question Paper Page 4
Q29. Draw a well-labelled diagram of the human female reproductive system (sectional view), clearly
labelling the following parts: ovary, fallopian tube (with infundibulum and fimbriae), uterus, cervix and
vagina. (5)
— End of Question Paper —
CBSE Class 12 Biology | Chapter 2: Human Reproduction