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MBC Course Topics

The document outlines the curriculum for the 200L MBBS Medical Biochemistry program, detailing various subjects including Nucleic Acid Chemistry, Enzymes and Bioenergetics, Amino Acid Metabolism, Carbohydrate Metabolism, and Lipid Metabolism. Each subject includes key topics such as genome organization, enzyme kinetics, amino acid metabolism processes, carbohydrate pathways, and lipid biosynthesis. The course aims to provide a comprehensive understanding of biochemical processes relevant to medicine.

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0% found this document useful (0 votes)
2 views5 pages

MBC Course Topics

The document outlines the curriculum for the 200L MBBS Medical Biochemistry program, detailing various subjects including Nucleic Acid Chemistry, Enzymes and Bioenergetics, Amino Acid Metabolism, Carbohydrate Metabolism, and Lipid Metabolism. Each subject includes key topics such as genome organization, enzyme kinetics, amino acid metabolism processes, carbohydrate pathways, and lipid biosynthesis. The course aims to provide a comprehensive understanding of biochemical processes relevant to medicine.

Uploaded by

tom654holland
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

MBC 202

Nucleic Acid Chemistry


Prof. Oseni O. A.

01 Genome organization.

02 Nucleic acids (DNA and RNA), Structures of bases and sugars in


nucleic acids.

03 Nucleotides and nucleosides.

04 Structures (Primary, secondary, tertiary, and quaternary) of nucleic


acids.

05 Watson-Crick base pairing rules: A=T, G≡C.

06 H-bonds and stability.

07 Structures and types of RNAs.

08 Physical and Chemical Properties of nucleic acids.

09 Modified nucleotides and analogues.

10 Replication of nucleic acid and nucleic acid sequencing.

11 Human Genome Sequencing Project and Its Clinical Relevance.

200L MBBS – Medical Biochemistry – Second Block


MBC 204

Enzymes, Coenzymes and


Bioenergetics
Dr. Ogunmoyole T.

01 Introduction to enzymes.

02 Properties and functions, nature and properties of enzymes.

03 Kinetics of enzyme action, allosteric effects.

04 Enzyme assay in clinical medicine, immobilised enzymes, hybridoma


technology, and monoclonal antibodies in medicine and biological
research.

05 The role of electron transport chain and oxidative phosphorylation in the


generation of ATP, theories and models proposed for ATP generation.

200L MBBS – Medical Biochemistry – Second Block


MBC 206

Amino Acid Metabolism


Prof. Awoyinka O. A. / Mr Ayita E. D.

01 Introduction to the metabolism of amino acid.

02 Transamination, oxidative deamination, decarboxylation.

03 The urea cycle and its biochemical importance.

04 Biosynthesis and degradation of amino acids.

05 Inborn errors of metabolism of some amino acids, phenylketonuria,


tyrosinosis, alkaptonuria, albinism, cystinuria.

200L MBBS – Medical Biochemistry – Second Block


MBC 208

Carbohydrate Metabolism
Dr. (Mrs) Oladele F. C.

01 Glycolysis (Embden-Meyerhof pathway), aerobic and anaerobic


phases.

02 Control mechanisms and substrate level phosphorylation.

03 The kerb’s cycle/citric acid cycle.

04 Metabolism of galactose and fructose, the uronic acid pathway,


gluconeogenesis, glycogenesis and glycogenolysis.

05 The HMP shunt and its biochemical importance.

200L MBBS – Medical Biochemistry – Second Block


MBC 212

Lipid Metabolism
Mr Ayita E. D.

01 Biosynthesis of fatty acids, triacylglycerol and phospholipids.

02 Fatty acid oxidation, Ketogenesis and its clinical relevance.

03 Cholesterol metabolism, Arachidonate metabolism (prostaglandins,


prostacyclins, thromboxanes, leukotrienes), phospholipids, and
glycolipid metabolism and their clinical relevance.

04 Disorders of lipid metabolism.

200L MBBS – Medical Biochemistry – Second Block

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