SCHOOL OF NURSING
THE ASSAM KAZIRANGA UNIVERSITY
HEALTH EDUCATION
ON
S
TUBERCULOSIS
SUBMITTED TO:
SUBMITTED BY:
MRS. VINEETHA. M
MR. SHAMEZ UDDIN KHAN
ASSOCIATE PROFESSOR
B.S.C. NURSING 3RD SEM
MEDICAL SURGICAL NURISNG
SCHOOL OF NURSING
SCHOOL OF NURSING
STUDENT PROFILE
Name of the instructor :
Name of the Groups :
Course :
Name of the Topic :
Subject :
Date :
Time :
Venue :
Name of Student :
Method of Teaching : Lecture methods, Lecture cum discussion.
AV AIDs : Blackboard and chalk, Pictures, Charts, leaflets, pamphlet, and
Powerpoint presentation with videos assisted teaching.
General Objective:
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INTRODUCTION
Tuberculosis (TB) is an infectious disease caused by
Mycobacterium tuberculosis. It usually involves the lungs,
but any organ can be infected, including brain, kidneys,
and bones. About one third of the world's population are
infected with TB. According to 2019 estimates, nearly 10
million people had tuberculosis in the world, with 1.2
million being children. TB is one of the 10 leading causes
of death in the world. Worldwide 1.4 million people died
of the disease (including 208,000 people with HIV).¹¹ It is
the leading cause of mortality in patients with HIV
infection. The incidence of TB worldwide declined until
the mid-1980s when HIV disease emerged. The major
factors contributing to the resurgence of TB were: (1) high
rates of TB among patients with HIV infection and (2) the
emergence of MDR strains of M. tuberculosis.
DEFINITION
"Tuberculosis is defined as, "A contagious bacterial
infection caused by Mycobacterium tuberculosis that
involves the lungs"."
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TYPES OF TUBERCULOSIS
1. Primary tuberculosis is the form of disease that
develops in a previously unexposed and therefore
unsensitized person. It is the initial infection,
characterized by Ghon’s complex (lesion in lung
caused by TB). The chief implications of primary
tuberculosis are as follows:
a. It induces hypersensitivity and increased resistance.
b. The foci of scarring may harbor viable bacilli for
years, perhaps for life, and thus be the nidus for
reactivation at a later time when host defenses are
compromised.
c. Uncommonly, the disease may develop without
interruption into so-called progressive primary
tuberculosis.
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2. Secondary (or post primary) tuberculosis is the pattern
of disease that arises in a previously sensitized host. It may
follow shortly after primary tuberculosis, but more
commonly it arises from reactivation of dormant primary
lesions many decades after initial infection, particularly
when host resistance is weakened.
3. Miliary tuberculosis occurs when organisms drain
through lymphatics into the lymphatic ducts, which empty
into the venous return to the right side of the heart and then
into the pulmonary arteries. Individual lesions are either
microscopic or small, visible (2 mm) foci of yellow-white
consolidation scattered through the lung parenchyma (the
word miliary is derived from the resemblance of these foci
to millet seeds).
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ETIOLOGY
Agent Factors
Mycobacterium tuberculosis is a facultative intracellular
parasite, i.e. it is readily ingested by phagocytes and is
resistant to intracellular killing.
Source of Infection
1. Human source: Human to human.
2. Bovine source: The bovine source of infection is usually
infected milk.
Community
Patients are infective as long as they remain untreated and
effective antimicrobial treatment reduces infectivity by
90% within 48 hours.
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Host Factors
1. Age: Tuberculosis can affect all age groups.
2. Sex: More prevalent in males than in females.
3. Hereditary: Tuberculosis is not a hereditary disease.
4. Immunity: Man has no inherited immunity against
tuberculosis.
Mode of Transmission
Tuberculosis is transmitted mainly by droplet infection and
droplet nuclei generated by sputum, positive patients with
pulmonary tuberculosis.
Incubation Period
The time from receipt of infection to development of the
tuberculin test ranges from 3 to 6 weeks.
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RISK FACTORS
1. The most common risk factor associated with TB is
HIV and other conditions that impair the immune system.
2. Patient’s dependent on alcohol or other chemical
because of malnutrition, debilitation and generally poor
health; older alcoholics who are of minority races are even
at greater risk.
3. Infants and children under the age of 5 years.
4. People with lifelong conditions, such as diabetes or
kidney diseases.
5. People who inject drugs.
6. Tobacco use.
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PATHOPHYSIOLOGY OF TUBERCULOSIS
1. Main Pathophysiology Flow
Exposure to Mycobacterium tuberculosis
↓
Entry as droplet infection into alveoli and bronchioles
↓
Multiplication of bacteria
↓
Local inflammatory response: exudate in alveoli resulting
in bronchopneumonia
↓
Granuloma formation
Infected macrophages spread infection to lymph nodes:
'Primary Ghons Focus' formation
↓
3 Possible Outcomes:
1. Infection clears
2. Primary TB
3. Latent TB
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2. Progression to Disease
From Primary TB:
Primary TB → Progressive disease → Pulmonary TB /
Extrapulmonary TB / Miliary TB
From Latent TB:
Latent TB → Progressive disease → Pulmonary TB /
Extrapulmonary TB / Miliary TB
3. Factors Affecting Transmission
• Bacillus load
• Concentration of bacillus
• Length of time of exposure
• Immune system of the exposed person
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4. Factors for Reactivation: Latent TB → Progressive
Disease
• Immunodeficiency
• Extremes of age
• Severe malnutrition
• Immunosuppression
• Drug addiction
• Chronic diseases
• Diabetes
• Pregnancy
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CLINICAL MANIFESTATIONS
[Link] symptoms
• Persistent cough for more than 2–3 weeks (starts as dry,
later becomes productive)
• Sputum may be mucoid or mucopurulent
• Chest pain
• Shortness of breath (dyspnea) – usually a late symptom
• Hemoptysis (coughing up blood) – seen in some patients
2. Constitutional (general) symptoms
• Low-grade fever (especially in the evening)
• Night sweats
• Fatigue
• Malaise (feeling weak and unwell)
• Loss of appetite (anorexia)
• Unexplained weight
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3. Acute presentation (in some patients)
• High fever
• Chills
• Flu-like symptoms
• Pleuritic chest pain
• Productive cough
4. Extrapulmonary TB symptoms
• Depend on the organ affected:
- Kidney TB → Painful urination (dysuria), blood in
urine (hematuria)
- Bone and joint TB → Severe bone/joint pain
- TB meningitis → Headache, vomiting, enlarged lymph
nodes
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DIAGNOSTIC EVALUATION
1. Medical history.
2. Physical examination: It reveals the following:
a. Clubbing of the fingers or toes (in people with
advanced disease).
b. Swollen or tender lymph nodes in the neck or other
areas.
c. Fluid around the lung.
3. Tuberculin skin test or mantoux test:
a. It is a standardized test.
b. Tubercle bacilli extract Purified Protein Derivate
(PPD) is injected in the intradermal layer of inner aspect of
forearm.
c. PPD intermediates strength, e.g. 5 tuberculin units in a
tuberculin syringe with a 26 to 27 gauge needle is used.
d. Needle is inserted under the skin only 0.1 ml of PPD is
injected, creating an elevation in the skin.
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e. Test is considered positive, if a raised area of in duration
occurs within 48-72 hours. A positive result indicates that a
person has been exposed to infection. It does not mean that
active disease is present.
f. Size of induration: It denotes the significance of
reaction.
i. Not significant – 0 to 4 mm.
ii. May be significant – 5 mm or greater.
iii. Significant – 10 mm or greater.
4. Chest X-ray: In TB infection, there are changes in the
structure of lungs, which of lungs are visible on the X-ray.
5. Sputum culture test: Diagnosis of tuberculosis is
confirmed by finding acid fast bacillinum smears of
sputum.
6. Quanti FERON -TB Gold test: It is a blood test which is
performed to detect active and latent tuberculosis.
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7. Drug susceptibility testing: It provides a definitive
diagnosis of drug-resistant TB.
8. Other tests: These be done to confirm diagnosis and
rule out other problems:
a. Bronchoscopy: In this procedure, a scope is inserted
through mouth or to nose that allow doctor to see patient’s
lungs and airways.
b. CT scan: Performed to check lungs for signs of an
infection.
c. MRI: A magnetic field and radio waves are used to
produce detailed images of the inside of the body.
d. Ultrasound scan: High frequency sound waves create
an image of part of the inside of the body.
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MEDICAL MANAGEMENT
Essential Drugs
1. First line drugs: These are the drugs which first
administered for disease. They have high clinical
effectiveness. They include the following:
a. Isoniazid
b. Ethambutol
c. Rifampicin
d. Streptomycin
e. Pyrazinamide
2. Second line drugs: They are used for the manage-
ment of drug resistant tuberculosis. They include the
following:
a. Kanamycin
b. Ethionamide
c. Para-amino salicylic acid
d. Cycloserine
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Components of TB treatment under RNTCP (Revised
National Tuberculosis Control Programme):
1. Domiciliary treatment
2. Short course chemotherapy
3. Intermittent regimen
4. Direct Observation of Treatment (DOT)
NURSING MANAGEMENT
1. The nurse should teach patient and family that TB is
infectious but it may be cured, if patient take his/her
medication as prescribed by the doctor.
2. Monitor respiratory rate, breath sounds, chest
symmetry and bilateral air entry.
3. Elevate the head of bed and assist the patient to assume
semi-fowler’s position.
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4. Change positions every 2 hourly.
5. Provide information regarding side effects of
prescribed medications.
6. Encourage patient for deep breathing exercises.
7. Instruct patient to cover his/her mouth or nose when
coughing, laughing or sneezing.
8. Instruct patient to wear mask in appropriate situations
when adviced.
9. Provide emotional and psychological support to patient
and family.
10. Provide high protein diet such as soyabean, milk,
leafy vegetables to patient.
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PREVENTION
[Link] patient to use a tissue to cover mouth and nose
while coughing and sneezing.
2. Used tissues should be flushed down the toilet or
disposed off carefully in the waste bin.
3. Instruct patient to perform frequent hand washing and to
wear facial mask.
4. Teach all family members also about importance of hand
washing.
5. Respiratory isolation is recommended until effective
drug therapy puts a stop to infectiousness. Risk of
transmission reduces after 2 weeks of drug therapy.
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COMPLICATIONS
1. Miliary TB: Invade in bloodstream.
2. Pleural effusion and empyema.
3. Tuberculosis pneumonia.
4. Other organ involvement such as CNS with
inflammation of meninges, bone (Pott’s disease of spine),
joints, kidney, lymph node, spleen, etc.
5. Hepatitis (inflammation of liver)
6. Change in vision.
7. Massive hemoptysis
REFERENCE
1) Medical Surgical Nursing -1 LEWIS
2) Adult Medical Surgical Nursing -1 DR. JOGINDRA
VATI PRABHJOT KAUR LAKHWINDER KAUR