PAPER I

THE CELL AS A UNIT OF HEALTH AND DISEASE

S. No. Topic Exam Date(s)
1 Discuss the role of myofibroblasts in health and disease Nov-11
Signal transduction proteins, mode of action, and association with
2 May-20
cancer
3 Extracellular matrix in health and disease May-20
4 Discuss the role of stem cells in health and disease May-22
5 Discuss the role of HLA in health and disease Nov-22
6 Role of neutrophils in health and disease Nov-21

INFLAMMATION AND REPAIR

S. No. Topic Exam Date(s)
Nov-12, Nov-
1 Role of oxygen free radicals in disease
17
2 Free radical injury May-18
May-13, Nov-
3 Role of adhesion molecules in inflammation
18, Nov-21
4 Angiogenesis May-13
5 Mechanisms of angiogenesis Nov-13
Discuss chemokines with special emphasis on their role in
6 May-14
inflammation
Nov-18, Nov-
7 Cytokines
20
Define inflammation. Discuss the role of various chemical
8 Nov-14
mediators in acute inflammation
9 Pathogenesis of tuberculosis May-16
10 Granulomas Nov-14
11 Types of collagens Nov-14
May-17, Nov-
12 Selectins and their role in inflammation
15
May-16, Nov-
13 Growth factors involved in tissue regeneration and repair
17
14 Role of extracellular matrix in cell growth and healing May-19
15 Alcohol-induced liver changes Nov-19
16 Endothelium in health & disease May-20

CELL INJURY, CELL DEATH, AND ADAPTATIONS

S. No. Topic Exam Date
Discuss mechanical defects in protein folding and its role in
1 Nov-11
health and disease
2 Mechanism of cell injury Nov-11
3 Reperfusion injury Nov-19
4 Role of Telomerase Nov-11
5 Telomere May-18
Pathogenesis of ischemic and hypoxic cell injury; role of growth
6 May-12
factors and cytokines in regeneration and wound healing
7 Disorders associated with defects in receptor proteins May-12
8 Discuss the role of endothelium in health and disease Nov-12
Nov-12, Nov-
9 Pathogenesis of pathological calcification
18
10 Types of necrosis Nov-10
May-13,
11 Biochemical features and mechanisms of apoptosis
May-17
12 Mechanism of apoptosis May-17
13 Discuss the role of apoptosis in health and disease Nov-13
14 Mitochondrial pathway of apoptosis May-14
 15 Discuss apoptosis and differentiate from necrosis May-18
16 Reactive oxygen species in cell injury May-14
Nov-14, May-
17 Cellular aging
19
Nov-14, Nov-
18 Pathologic calcification
23
19 Mechanism of cell death in ionizing radiation May-19
20 Apoptosis in health and disease May-15
21 Phagocytosis May-16
22 Advances in apoptosis May-20
23 Stains for melanin May-22
24 Zebra bodies May-22
25 Chaperone proteins Nov-22
26 Pigmented disorders Aug-23
27 Ochronosis Aug-23

HEMODYNAMICS

Here is the tabulation of topics and exam dates:

S. No. Topic Exam Date

1 Hypercoagulable states and its complications May-12
Endothelial properties responsible in maintenance of normal
2 Nov-17
hemostasis
3 Virchow’s triad Nov-19
4 Acquired causes of thrombotic diathesis May-13
5 Pathogenesis of septic shock Nov-10
6 Pulmonary embolisms May-18
7 Oedema: pathogenesis, morphology, types Nov-10
8 The pathogenesis of thrombus formation May-17
 May-19, Aug-
9 Pathophysiology of thrombosis
22
10 Pathology of multiple organ failure syndrome May-20
11 Pathology of systemic inflammatory response syndrome Aug-22
12 Platelet-derived inflammatory mediators Aug-23

IMMUNOPATHOLOGY
S. No. Topic Exam Date(s)
1 Lab diagnosis of amyloidosis May-12
Describe the chemical nature of amyloid. Add a note on renal
2 Nov-19
amyloidosis
3 Anaphylaxis May-12
4 Etiopathogenesis of amyloidosis Nov-12
5 Mechanism of immunological tolerance Nov-12
6 Lab diagnosis of amyloidosis May-12
Discuss the mechanism of autoimmune diseases. Describe the
7 etiopathogenesis, pathology, and laboratory diagnosis of systemic
lupus erythematosus
8 Etiopathogenesis of autoimmune diseases May-19
9 Antiphospholipid antibody syndrome Nov-13
10 Natural Killer cells Nov-13
11 Type II hypersensitivity reaction May-16
12 T Cell mediated (type IV) hypersensitivity Nov-13
13 Factors influencing transplant rejection Nov-17
May-14,
14 Graft versus host disease
May-22
15 Factors influencing transplant rejection May-19
16 Immunopathology of HIV infection May-14
17 Pathogenesis of HIV infection May-16
 May-17, Aug-
18 Pathogenesis of CNS involvement in HIV infection
22
19 Antineutrophil cytoplasmic antibodies May-15
20 Neurosyphilis May-18
21 Classification of autoimmune diseases May-18
22 Tumor immunity May-19
23 Transplant rejection and graft survival Nov-10
24 Role of histopathology in deep fungal infection Nov-21
25 Systemic sclerosis etiopathogenesis May-20
26 Secondary manifestations of HIV May-22
27 Type III hypersensitivity reaction May-22
28 Differential diagnosis of granulomatous disease Aug-22
29 Minor histocompatibility antigen Aug-23

ENVIRONMENTAL AND FETAL DISEASE, NUTRITION

S. No. Topic Exam Date(s)
Nov-11, May-
1 Vitamin D deficiency
17
2 Beriberi Nov-19
3 Trace elements Nov-17
4 Classify obesity, Role of leptin in obesity May-20
5 Pathogenesis of disorders caused by smoking May-12
May-15, May-
6 Acute radiation injury
20
7 Classify leprosy, immunopathology May-20
8 Protein energy malnutrition May-22
9 Effects of hyperthermia Nov-22
10 Etiopathogenesis of congenital anomalies Aug-22
11 Occupational lung disease Aug-22
12 Diseases due to chemicals in agricultural field Nov-21
13 Biomedical waste disposal in pathology lab Nov-21

NEOPLASIA
S. No. Topic Exam Date(s)
1 Role of nutrition in cancer Nov-11
2 Geographic and environmental factors in neoplasia May-12
3 Discuss the molecular basis of carcinogenesis Nov-12
Discuss the important chemical carcinogens and the mechanism
4 May-17
of chemical carcinogenesis
May-18,
5 Viral carcinogenesis
May-16
May-13, Nov-
6 Tumour suppressor genes
17
7 Tumour antigens Nov-18
8 Discuss the role of microsatellite instability in neoplasia May-14
9 Genomic imprinting Nov-14
10 DNA repair defects and cancer Nov-16
Discuss mechanism of metastasis and outline the role of
11 Nov-18
extracellular matrix in tumor progression
May-15, Nov-
12 Warburg effect
22
Nov-18, May-
13 Tumour markers
20
14 Angiogenesis Nov-10
Mention the various paraneoplastic syndromes. Add a note on May-18, Nov-
15
tumour markers. 21
16 Wilms tumour Nov-19
17 WNT signaling pathway in carcinogenesis May-18
18 Matrix metalloproteinases May-20
19 Mechanism of homing of cancer cells May-20
20 Molecular mechanism of genes involved in metastasis May-20
21 BRAF mutations and carcinogenesis May-22
22 Tumor lysis syndrome Nov-22
23 Epigenetics in cancer Nov-22
24 Oncogenes - Classification, detection, analysis Aug-23
25 Cell-free DNA and its utility in cancer diagnosis Nov-21

GENETICS
S. No. Topic Exam Date(s)
Nov-11, May-
1 Molecular diagnosis of genetic diseases
16
2 Mary Lyon’s hypothesis and Barr bodies Nov-17
3 Molecular and genetic basis of Mendelian disorders May-19
May-17, May-
4 Karyotyping - the different methods involved
22
5 Down syndrome May-12
6 Marfan syndrome May-13
7 Ehlers-Danlos syndrome (EDS) Nov-13
8 Fragile X syndrome May-14
9 Recombinant DNA techniques May-18
10 Gene therapy Nov-17
11 Mucovisidosis Nov-19
May-20, Aug-
12 Genomic imprinting
22
13 Tissue microarray May-20
14 DNA fingerprinting May-20
15 FISH, TISH Nov-22
16 Next-generation sequencing Nov-22
17 Describe the role of oncogenes in cancer Aug-22
18 Gene cloning - Merits & demerits Aug-23
19 Autosomal dominant disorders, general features, examples Nov-21

MISCELLANEOUS AND INFECTIOUS DISEASES

S. No. Topic Exam Dates
1 Role of viruses in diseases May-12
2 Viral inclusions Nov-18
3 Pathology of heavy metal poisoning May-19
4 Zygomycosis May-19
5 Role of FNAC in testicular tumours Nov-12
6 Discuss the role of autopsy as a diagnostic tool May-13
7 Proteomics May-14
8 Occupational diseases Nov-19
Discuss the pathogenesis and diagnosis of various fungal infections
9 Nov-14
of the skin
10 Granulomatous inflammations Nov-19
May-15,
11 Discuss the pathogenesis and morphology of leprosy
Nov-21
12 Prion diseases May-15
13 Clinical utility and methodology of telepathology May-15
Discuss the role of electron microscopy in diagnostic surgical
14 May-17
pathology
15 Cell adhesion molecules Nov-10
16 Role of endothelial cells in health and disease Nov-10
Nov-16, Nov-
17 Role of stem cells in health and disease
18
18 Stem cells in metaplasia and fibrosis Nov-15
19 Polymerase chain reaction Nov-17
20 Acute phase reactants Nov-19
21 Ghon’s complex May-22
22 Sudden infant death syndrome Nov-22
23 Homeobox proteins Nov-22
24 Amniotic fluid examination Nov-22
25 Spleen in hematological disease Aug-22
26 Role of mucin stains in histopathology Aug-22
27 Application of CT in autopsy studies Aug-22
28 Tissue processing for electron microscopy Aug-22
29 Flow cytometry in a diagnostic laboratory Aug-23
30 Write in detail about isoenzymes Aug-23
31 Histopathologist and internet Aug-23
32 Silver impregnation technique Aug-23
33 Role of autopsy in maternal deaths Nov-21

PAPER II
HEMATOLOGY, ANEMIAS

S. No. Topic Exam Date(s)

May-15, Nov-
1 Congenital dyserythropoietic anemia
19
2 Hemosiderinuria May-15
3 Pure red cell aplasia Nov-14
4 Discuss the role of red cell indices in evaluation of anemia Nov-13
May-13, Nov-
5 Anemia of chronic disease
22
Discuss anemias of diminished erythropoiesis and write about
6 peripheral smear and bone marrow findings to establish the Nov-11
diagnosis
Etiopathogenesis, pathogenesis, and lab diagnosis of
7 May-11
megaloblastic anemia
8 Reticulocyte and its importance in hematology May-18
May-18, Nov-
9 Pathological inclusions in RBC
18
10 Vitamin B12 assay May-19
11 Bone marrow in megaloblastic anemia Nov-18
12 Role of HPLC in hemoglobinopathies Nov-14
13 Hemoglobinuria May-14
May-14, Aug-
14 Molecular basis of thalassemias
23
Discuss the pathogenesis and lab diagnosis of Paroxysmal
15 Nov-19
nocturnal hemoglobinuria
16 Coombs test Nov-13
Nov-19, May-
17 Immune hemolytic anemia, lab diagnosis
20
18 Aplastic anemia May-18
19 Inherited red cell membrane disorders Nov-18
20 Red cell enzyme deficiencies - etiopathogenesis and lab findings May-20
Aug-22, Nov-
21 Hemoglobinopathies
22
22 Bone marrow failure Aug-23

DISORDERS OF WHITE BLOOD CELLS

S. No. Topic Exam Date(s)
Discuss the classification and lab diagnosis of Myelodysplastic
1 May-15
Syndromes
Classify acute leukemia. Describe the morphology of cells in each May-18, Nov-
2
type 18
3 WHO classification of acute myeloid leukemia May-17
4 Acute leukemia Nov-10
5 Primary myelofibrosis May-15
6 Myelofibrosis May-19
Cytogenetic abnormalities in Acute Myeloid Leukemias and
7 Nov-14
molecular basis of Acute Promyelocytic Leukemia
8 Prolymphocytic leukemia Nov-13
9 Discuss the role of flow cytometry in acute leukemias Nov-13
10 Hairy cell leukemia May-13
Molecular pathogenesis & morphology of myeloproliferative
11 Nov-18
disorders
May-12,
Various classification systems for acute myeloid leukemia &
12 May-16, Nov-
morphology, genetic aberrations, and prognosis
12
13 Myelodysplastic syndrome May-17
Nov-11, May-
14 Classification of acute lymphoblastic leukemia
11
15 Paraproteinaemias May-11
16 Preleukemic conditions May-19
17 Lazy leucocyte syndrome May-19
18 Lab diagnosis of multiple myeloma Nov-18
19 Biphenotypic leukemia May-16
20 Childhood leukemia Nov-19
21 MRD (Minimal Residual Disease) in hematological malignancies May-20
May-20,
22 T & NK Cell neoplasm May-22, Aug-
22
Role of IHC in distinguishing mantle cell from marginal zone
23 May-20
lymphoma
24 Hematogones May-22
May-22, Aug-
25 Allogenic stem cell transplant
22
26 Lesions associated with thymomas May-22
27 Dendritic cell sarcoma May-22
28 Immunophenotyping and cytogenetics of acute leukemia Nov-22
29 Chromosomal translocations in AML Aug-22
30 Prognostic factors in acute leukemias Aug-23
31 Polycythemia vera - etiopathogenesis, lab findings Nov-21
32 Jaundice in pediatric age group Nov-21
33 Primary effusion lymphomas Nov-21

HEMATOLOGY, DISORDERS OF HEMOSTASIS

S. No. Topic Exam Date(s)
1 Lab diagnosis of Hemophilia A May-15
Discuss the causes and laboratory diagnosis of hereditary May-17, Nov-
2
thrombophilia 22
May-18, Nov-
3 Factor VIII deficiency
18
Nov-01-2014,
4 Classification and lab diagnosis of von Willebrand disease
Nov-21
5 Inherited platelet disorders May-14
6 Inherited thrombotic disorders May-13
7 Disorders of platelet function Nov-10
8 Causes of thrombocytopenia Nov-18
9 Differential diagnosis of elevated APTT May-20
10 Platelet function tests Aug-22
11 Porphyrias May-12
12 Noninfectious vasculitis Nov-11
13 Plasmapheresis Nov-11
14 Investigation in a case of thrombotic disease May-11
Nov-10, Aug-
15 Screening tests and special tests in bleeding disorders
23
16 Role of coagulation factors in disease Nov-19
17 Thrombocytopenias Nov-19
May-20, Aug-
18 Automation in hematology
22
19 Role of delta check practices in hematology quality control Nov-22
20 HPLC in hematology Nov-22
21 Diagnosis of platelet function disorders Nov-21
22 Waldenstrom’s macroglobulinemia Nov-21

BLOOD TRANSFUSION
S. No. Topic Exam Date(s)
1 Automation in blood banking May-15
2 Leukopheresis Nov-14
3 Bombay blood group May-14, 20
4 Minor blood group systems Nov-19
5 Allogenic stem cell transplant May-13
6 Platelet transfusion May-13
7 Stem cell transplantation May-11
8 Blood components, preparation and usage May-11
Standard protocols and requirements in establishing a modern
9 May-18
blood bank
10 Autologous transfusion May-17
11 ABO discrepancy and its resolution May-17
12 Diseases transmitted by blood transfusion May-19
13 Quality control in blood bank May-19
14 Relevance of blood donor screening May-16
15 Safe blood transfusion Nov-18
16 ABO discrepancy and its resolution May-17
17 Automated instruments in haematology lab Nov-18
May-16, 22,
18 Quality control and quality assurance in blood banking
Aug-22
19 Packed cell volume Nov-18
20 Blood substitutes May-20
21 Investigation in mismatched transfusion May-20
22 Cryoprecipitate May-22
23 Individual donor NAT Nov-22
24 Apheresis Aug-22
25 Rational use of blood components Nov-21

CYTOPATHOLOGY FNAC
S. No. Topic Exam Date(s)
1 Discuss squash technique and its application in brain lesions May-15
2 Role of FNAC in thyroid lesions May-19
3 FNAC of solitary thyroid nodule Nov-14
Discuss the cytologic differential diagnosis of Space occupying
4 Nov-13
lesion (SOL) in the liver
5 Discuss the role of FNA in the evaluation of mediastinal masses May-13
6 FNAC of cystic lesions in the neck May-13
Nov-12, Aug-
7 Discuss the role of FNAC in soft tissue tumours
23
8 Role of FNAC in mucinous lesions of breast May-18, 20
Discuss the role of intraoperative cytology in the diagnosis of
9 May-17
breast lesions
Discuss the cytologic findings and differential diagnostic
10 May-14
considerations in salivary gland lesions
11 Discuss the role of Cytopathology in metastatic neoplasia May-12
12 Diagnosis of primary & secondary lymphomatous effusions Nov-12
Discuss the role of cytology in the diagnosis of lower respiratory
13 May-11
tract lesions
14 Role of intraoperative cytology in the diagnosis of breast lesions May-17
15 Interventional cytology Nov-19
 01-05-2020,
16 Milan system of salivary gland cytopathology
Nov-21
17 Bethesda system for reporting thyroid cytopathology Nov-22
Role of FNA in diagnosis of non-neoplastic lesions of lymph
18 Aug-22
node
19 Bethesda system for reporting thyroid cytopathology Aug-23
Discuss the role of CT guided FNAC in the diagnosis of
20 Aug-23
pulmonary lesions
21 Intraoperative cytology of pancreatic lesions Aug-23
22 Discuss Bethesda system of pancreatic tumors Nov-21

URINE CYTOLOGY
S. No. Topic Exam Date(s)
1 Role of urinary sediment examination Nov-12
2 Discuss in detail about urine cytology in metabolic diseases Nov-11
3 Microscopy of urine May-19
4 Investigation of albuminuria Nov-12
5 Pathological proteins in urine May-18
6 Role of urine microscopy in the diagnosis of diseases May-17
7 Urinary sediments renal stones Nov-10
8 Paris system of reporting urine cytology May-20
9 Automation in cytology May-22
10 Telescoped urinary segment May-22
11 Cytocentrifuge Aug-22
PAP SMEAR
Exam
S. No. Topic
Date(s)
1 Cytomorphologic features of HPV infection in cervicovaginal smears May-15
2 Discuss the role of automation in cervical cytology Nov-14
3 Interpretation of pap smear May-19
4 Cytologic evaluation of hormonal status in vaginal smears May-14
Discuss the cytomorphology, significance & differential diagnosis of
5 Nov-13
endometrial cells in cervical cytology
6 Thin prep cytology Nov-12
7 Recent advances in endocervical pathology May-12

MISCELLANEOUS – I
Exam
S. No. Topic
Date
1 APLA syndrome Nov-14
May 2014,
2 Discuss the hematologic manifestations of HIV infection
Nov-21
3 Mast cells in health and disease May-14
4 Discuss the principles in automated cell counters May-13
5 Automated instruments in haematology laboratories May-18
6 Recent advances in diagnosis of Malaria May-13
Nov-12,
Discuss the role of bone marrow biopsy in the diagnosis of
7 May-16,
haematological disorders
May-17
8 Artificial neural networks in diagnostic pathology May-12
9 Microwave tissue processing May-12
10 Lab diagnosis of diabetes mellitus May-12
11 Role of immunohistochemistry in diagnosis of soft tissue tumors Nov-11
12 Classify disorders associated with splenomegaly Nov-11
13 Semen analysis in IVF clinic May-11
Nov-19,
14 Semen analysis, Approach to male infertility
20, 23
Structure and function of HLA and list of disorders associated with
15 Nov-11
certain HLA alleles
16 Preparation and uses of cell block technique May-18
17 Utility of cytospin in clinical laboratory Nov-12
18 Clinical applications of flow cytometry May-12
May-17,
19 Synovial fluid examination
20, 21
20 Bone marrow biopsy May-17
21 Processing of body fluids in cytology lab May-16
22 Discuss flow cytometry as a diagnostic tool in pathology Nov-18
23 Discuss relevance of fluid cytology in pathology Nov-18
24 Role of electron microscopy in diagnostic surgical pathology May-17
25 Classification and features of jaundice Nov-10
26 Automation in clinical pathology Nov-10
27 Serum lipids in health and disease Nov-10
28 Cellular components in effusions Nov-19
29 Hematological manifestations in SLE May-20
May 2020,
30 Liquid based cytology
Nov-21
31 Hormone secreting tumors of exocrine origin Aug-21
32 Role of frozen section in diagnosis of storage disorders Nov-22
33 Microwave in histopathology -
34 Cytoskeletal abnormalities -
35 Fluorescent In Situ Hybridisation (FISH) -
36 Perinatal Autopsy -
37 Stem cells in therapy -
38 Polymerase chain reaction -
39 Bethesda system of reporting cervicovaginal smears -
40 Reactive pseudosarcomatous proliferations -
41 Quality control and quality assurance in surgical pathology -
42 Role of IHC in small round cell tumor -
43 Proliferation markers used in histopathology -
44 Hemolytic uremic syndrome -
45 Pseudotumor of orbit -
46 Maternal death autopsy -
47 Microalbuminuria -
48 Ethical issues in pathology laboratory -
Role of whole slide imaging (WSI) in pathology teaching and
49 -
practice
50 Succinate dehydrogenase mutant tumors -
51 IgG4 related disease -

PAPER III
CARDIOVASCULAR SYSTEM
Exam
S. No. Topic
Date(s)
 May-15,
1 Laboratory evaluation of myocardial infarction
Nov-18
Discuss the pathogenesis, pathology, lab diagnosis & complication
2 Nov-14
of ischemic heart disease
3 Recent trends in pathogenesis of coronary heart disease Nov-17
4 Restrictive cardiomyopathy May-14
5 Discuss the pathology of cardiomyopathies Nov-13
Discuss the etiopathogenesis, morphological changes and lab
6 May-13
diagnosis of myocardial infarction
7 Bacillary angiomatosis Nov-12
8 Primary pulmonary hypertension Nov-12
9 Cardiac effects of noncardiac neoplasms May-12
10 Endomyocardial fibrosis May-12
11 Pathogenesis of heart lesions in rheumatic fever May-12
12 Pathogenesis of atherosclerosis May-12
13 Vascular pathology in hypertension Nov-11
Describe the current concepts in the pathogenesis of atherosclerosis
14 May-11
and discuss the morphology of myocardial infarction
May-11,
Nov-15,
15 Endomyocardial Biopsy
May-19,
20
May-18,
May-16,
16 Types of cardiomyopathies
Nov-20,
May-22
17 Complications of heart transplantation May-17
18 Classification and pathogenesis of vasculitis Nov-16
Importance of examination of left ventricle in pathology
19 Nov-19
postmortems
20 Granulomatosis with polyangiitis Nov-22
21 Sudden cardiac death Aug-22
22 Classification and etiopathogenesis of vasculitis Aug-23
23 Vegetations of heart Nov-21

THE LUNG
Exam
S. No. Topic
Date(s)
1 Pulmonary alveolar proteinosis May-15
2 Solitary fibrous tumor May-15
3 DAD – Diffuse Alveolar Damage May-14
4 Discuss the pathogenesis and morphology of acute lung injury Nov-13
Describe the pathogenesis and pathology of non-cardiogenic
5 May-17
pulmonary oedema
May-13,
May-19,
6 Pathogenesis of asthma
Nov-16,
Nov-22
Use of electron microscopy and immunohistochemistry in diagnosis May-15,
7
of malignant mesothelioma Nov-22
8 Asbestos induced lesions of lung and pleura May-13
May-12,
9 Pathogenesis of ARDS (Acute Respiratory Distress Syndrome)
Nov-20
Nov-11,
10 Discuss about chronic obstructive pulmonary diseases
Nov-21
Classify bronchogenic carcinoma. Discuss its aetiopathogenesis, Nov-11,
11
gross, microscopic features and diagnosis Nov-18
May-16,
12 Recent WHO classification of lung tumors
May-18
May-19,
13 Neuroendocrine tumors of lung
Aug-22
14 Alpha 1 antitrypsin deficiency state Nov-18
15 HIV associated lung lesions Nov-17
16 Pleural tumors, pleural biopsy Nov-10
17 Types of secondary tuberculosis Nov-19
18 IHC & molecular genetics of lung cancer May-20
19 In situ lung cancers May-22
20 Classification of non-small cell lung carcinoma Aug-23

HEAD AND NECK AND SALIVARY GLAND

Exam
S. No. Topic
Date(s)
1 Differential diagnosis of salivary gland tumors with clear cells May-14
2 Classify and discuss salivary gland tumors Nov-13
3 Malignant epithelial tumors of salivary gland Aug-22
Classify and discuss salivary gland tumors, note on malignant
4 Aug-23
tumors of salivary gland
5 Discuss pathology of sinonasal tumors Aug-23

THE GASTROINTESTINAL TRACT

Exam
S. No. Topic
Date(s)
1 Barrett esophagus May-15
2 Gastrointestinal Lymphoma May-13
3 Endoscopic biopsy in chronic gastritis May-13
4 Role of helicobacter pylori in pathology May-18
5 Helicobacter pylori associated gastric lesions Nov-19
 Pathology and pathogenesis of lesions caused by helicobacter pylori
6 May-17
infection
7 MALT lymphoma of GIT May-19
8 Discuss the pathogenesis and pathology of Crohn’s disease. Nov-12
May-19,
9 Inflammatory bowel disease
Nov-20
May-12,
10 Describe the molecular genetics of colonic carcinoma
Nov-16
11 Prognostic factors in colonic adenocarcinoma Nov-15
12 Classify and discuss Neuroendocrine tumors of gastrointestinal tract May-12
13 Gastrointestinal polyps Nov-11
14 Colonic polyps Nov-19
15 Ulcers of the small and large intestine May-18
16 Premalignant lesions in GIT Nov-18
17 Serrated adenoma of colon Nov-17
18 Hereditary hyperbilirubinemia Nov-16
19 Celiac disease Nov-17
May-20,
20 Classification of gastric epithelial dysplasia
May-22
21 Role of biopsy in malabsorption syndrome May-20
22 Mucin stains in GI pathology Nov-20
Nov-22,
23 Hirschsprung disease
Aug-22
Premalignant lesions of colon, discuss gross and microscopic
24 Aug-23
features of ulcerative colitis
25 Pathology of major malabsorption syndrome Nov-21

LIVER, GALL BLADDER AND PANCREAS

Exam
S. No. Topic
Date(s)
1 Autoimmune hepatitis May-15
2 Pathology of Non-cirrhotic portal fibrosis Nov-14
Nov-14,
3 Etiopathogenesis & pathology of acute pancreatitis
May-16
4 NASH – Non-alcoholic Steatohepatitis May-14
5 Pathology of chronic hepatitis Nov-16
6 Grading and reporting of chronic hepatitis Nov-10
7 Pathogenesis and pathology of chronic hepatitis Nov-17
Classify gall stones and discuss the current concepts in the formation
8 Nov-13
of gall stones
9 Pathogenesis and pathology of gall stones May-18
10 Pathology of drug-induced liver injury May-13
11 Lab diagnosis of HBV Nov-20
12 Prognostic markers in HCC Nov-20
13 Budd-Chiari syndrome Nov-22
14 NAFLD (Non-Alcoholic Fatty Liver Disease) May-22
Discuss the differential diagnosis of granulomatous lesions in the
15 Nov-12
liver
Nov-17,
16 Biliary cirrhosis
Nov-19
17 Etiopathogenesis of primary carcinoma of liver May-16
18 Hepatitis C viral infection Nov-11
19 Fibrolamellar carcinoma Nov-11
20 Histological spectrum of hepatocellular carcinoma May-19
May-17,
21 Solid-cystic tumour of pancreas
20
22 Solid pseudo papillary tumors of pancreas Nov-10
23 Mucinous lesions of pancreas Nov-15
24 Wilson’s disease Nov-18
25 Exocrine tumors of pancreas Nov-19
26 Endocrine tumors of pancreas May-22
27 Etiopathogenesis and pathology of pancreatic carcinoma May-12

THE KIDNEY, ADRENALS AND RETROPERITONEUM

Exam
S. No. Topic
Date(s)
Nov-10,
1 Discuss cystic lesions of the kidney May-15,
May-14
2 Pathogenesis & pathology of tubulo-interstitial nephritis Nov-14
Describe the pathogenesis and morphology of renal changes in May 2014,
3
diabetes mellitus Nov-21
4 IgA nephropathy May-14
Discuss the recent concepts in transplant-related pathology of the
5 Nov-13
kidney
May-18,
6 Xanthogranulomatous pyelonephritis
Nov-22
7 Describe the mechanisms in progression of glomerular diseases May-17
Discuss in detail MPGN (Membranoproliferative
8 Nov-15
glomerulonephritis)
9 Pathology of renal graft rejection May-13
10 Nephroblastoma Nov-12, 20
11 Prognostic factors associated with Wilm’s tumor Nov-15
12 Renal dysplasia May-12
Role of immunofluorescence and electron microscopy in glomerular
13 May-12
diseases of the kidney
14 Renal cell carcinoma – histology and genetic alterations May-12
Nov-10,
15 Diabetic nephropathy
May-11
16 Primary malignant tumors of the retroperitoneal area May-14
17 Pheochromocytoma Nov-13
18 Diagnosis of pheochromocytoma May-13
19 Diagnostic role of electron microscopy in renal biopsy May-19
Discuss the renal biopsy findings in nephritic syndrome. Add a note
20 Nov-16
on the role of immunofluorescence
21 Etiology of urothelial carcinoma May-16
May-16,
22 Renal lesions in SLE
Nov-18
23 Alport’s syndrome Nov-18
24 Etiology of urothelial carcinoma May-16
25 Grading of urothelial tumors of the bladder Nov-17
26 Grading of urothelial carcinoma Nov-19
27 Bone metastasizing childhood renal tumors May-20
28 ADPKD (Autosomal Dominant Polycystic Kidney Disease) May-22
29 Immunohistochemistry (IHC) in renal tumors Aug-22
30 Childhood renal neoplasms Aug-23
Etiology, pathology, and recent developments in urinary bladder Aug 2023,
31
carcinoma Nov-21

MALE GENITAL SYSTEM

Exam
S. No. Topic
Date(s)
Nov-14,
1 Malakoplakia
Nov-22
2 Male infertility diagnosis Nov-12
May-12,
3 Testicular biopsy in male infertility May-16,
Nov-15
Nov-11,
4 Interpretation of Testicular Biopsy
Aug-23
5 Germ cell tumours of testis May-18
6 Premalignant lesions of prostate May-17
01-11-
7 Histologic variants of prostatic carcinoma 2010, Nov-
21
8 Causes of sterility in male Nov-18
9 Gleason's grading in prostatic carcinoma Nov-10, 20
10 Mimics of carcinoma prostate Nov-20
11 Prognostic markers in prostatic carcinoma May-22
12 Leydig cell tumor Nov-22
13 Intraductal carcinoma prostate Aug-23

BREAST
Exam
S. No. Topic
Date(s)
1 Discuss ductal carcinoma in situ with a note on its progression May-15
2 Predictive and prognostic factors of breast carcinoma May-14
May-17,
3 Ductal carcinoma in situ
Nov-17
4 Stromal tumors of breast Nov-10
Nov-11,
5 Discuss risk factors and prognostic indices of carcinoma breast
May-22
6 Role of IHC in breast carcinoma May-18
7 Prognostic markers in carcinoma breast Nov-19
01-11-
8 Triple negative breast cancer 2018, Nov-
21
9 Role of Her2 neu in breast carcinoma Nov-10
10 Molecular diagnosis of breast carcinoma May-19
11 Cystosarcoma phyllodes Nov-19
12 Circulating tumor cells in breast carcinoma May-20
13 Metaplastic carcinoma Nov-20
14 Staging of breast carcinoma Nov-22
Human epidermal growth factor receptor 2: testing methods and
15 Aug-22
utility

FEMALE GENITAL SYSTEM

Exam
S. No. Topic
Date(s)
May-14,
1 Discuss tumors and tumor-like conditions of intermediate trophoblasts
Nov-22
2 Discuss endometrial intraepithelial neoplasia Nov-13
Discuss the role of pathologist in diagnosis and management of primary
3 May-13
infertility
4 Tumor markers in ovarian tumors May-13
5 Endometrial hyperplasias May-18
6 Endometrial carcinoma Nov-12
7 Placental pathology in hypertensive disease of pregnancy May-12
8 Non-neoplastic cysts of ovary Nov-11
9 Discuss the classification of ovarian tumors Nov-16
10 Surface epithelial tumors of ovary May-19
11 Recent concepts in classification of epithelial ovarian tumors Nov-15
12 Ovarian teratoma May-18
13 Sex cord stromal tumors of the ovary Nov-19
14 Functional tumors of ovary Nov-17
15 Metaplasias of female genital tract May-17
16 Pathogenesis of cervical neoplasia Nov-10
17 Placental site trophoblastic tumour Nov-16
18 FIGO staging of ovarian tumors May-20
19 Complete vs partial mole Nov-20
20 Prognostic indices in epithelial ovarian neoplasms May-22
21 Inflammatory myofibroblastic tumor of female genital tract Aug-22
Pathology of endometrial hyperplasia, note on IHC marker in benign and
22 Aug-22
malignant lesions of endometrium
Classify ovarian tumors, write about histogenesis and etiopathology of
23 Aug-23
hormone-producing tumors
24 Endometrial dating Nov-21

PAPER IV
THE ENDOCRINE SYSTEM
Exam
S. No. Topic
Date(s)
Etiopathogenesis, pathology, and morphology of papillary carcinoma
1 May-15
of thyroid
May-16,
2 IHC and cytogenetics of papillary carcinoma of thyroid
Nov-20
3 Pathogenesis of autoimmune disorders affecting the thyroid Nov-14
Nov-13,
4 Pathology of papillary carcinoma of thyroid and its variants
May-19
Nov-12,
5 Recent variants of papillary carcinoma thyroid
May-18
Classify diabetes mellitus. Discuss pathogenesis and complications
6 May-19
of type 2 diabetes mellitus
May-17,
7 Medullary carcinoma thyroid
May-20
8 Variants of undifferentiated carcinoma of thyroid May-17
9 Pathology of a solitary nodule of thyroid Nov-18
10 Hashimoto's thyroiditis May-17
Discuss recent advances in pathogenesis and pathology of diabetes
11 May-16
mellitus
Nov-19,
12 MEN syndrome
Nov-22
13 Difficulties in diagnosis of papillary carcinoma thyroid May-22
14 Etiopathogenesis and morphology of Hashimoto's thyroiditis Aug-23

SKIN
Exam
S. No. Topic
Date(s)
1 Prognostic factors in Malignant Melanoma May-15
2 Unusual melanoma Nov-17
Morphology of cutaneous lesions in SLE and their differential
3 Nov-14
diagnosis
4 Progress in diagnosis & prognosis of malignant melanoma Nov-14
5 Cutaneous manifestations of nutritional deficiencies May-14
Nov-13,
6 Discuss cutaneous lymphoproliferative disorders
Nov-12
Discuss the role of immunofluorescence in interpretation of skin May-13,
7
biopsies May-19
Classify autoimmune disease and discuss in detail about Systemic
8 Nov-11
Lupus Erythematosis
9 Clinical types and prognosis of Cutaneous Malignant melanoma Nov-11
10 Precancerous lesions of skin tumours Nov-11
11 Premalignant lesions of skin Nov-19
12 Immunology of leprosy May-11
13 Gross and microscopic features of molluscum contagiosum May-18
May-17,
14 Spitz nevus
May-16
 Nov-18,
15 Merkel cell carcinoma
Aug-23
May-20,
16 Discuss cutaneous blistering disorders
Nov-22
17 Pigmented tumors of skin Aug-22
18 Skin adnexal tumors May-22
19 Darier’s disease Aug-22
20 Mycosis fungoides Aug-22

LYMPH NODES, MEDIASTINUM AND SPLEEN

Exam
S. No. Topic
Date(s)
1 Peripheral T cell lymphoma May-15
Nov-14,
2 Discuss the benefits of the recent WHO classification of thymomas
Nov-20
Nov-14,
3 Recent concepts in Hodgkin’s disease
Nov-20
4 Peripheral T – cell and NK cell Neoplasms Nov-14
5 Anaplastic large cell lymphoma May-14
6 Vascular disorders of the Spleen Nov-12
7 Effusion associated lymphomas Nov-12
Discuss the pathogenesis, pathology, and clinical features of Thymic
8 -
hyperplasia and Thymoma
Discuss classification of lymphomas and write in detail about May-12,
9
Burkitt's lymphoma May-11
10 Castleman’s disease May-18
11 Pitfalls in the interpretation of lymph node biopsies May-18
12 Systemic mastocytosis May-18
13 MALTOMA May-17
14 Di George syndrome May-19
15 Pathology of lymph node in HIV May-19
16 Non-neoplastic lesions of lymph node Nov-19
17 Cystic lesions of spleen Nov-16
18 Progressive transformation of germinal centre of lymph node Nov-15
Classification of NHL and note on diagnostic algorithm for IHC in
19 Nov-15
NHL
20 Kimura’s disease Nov-18
21 NK cell lymphoma May-16
22 Kaposi sarcoma Nov-17
23 Lymphoma in unusual sites and types Nov-17
24 Laboratory approach to splenomegaly Nov-19
Nov-20,
25 Langerhans Cell Histiocytosis (LCH)
May-22
26 HIV associated lymphoma Nov-20
27 Prognostic indicators in Hodgkin’s disease May-22
28 Rosai-Dorfman disease Nov-22
29 Histopathological variants of Hodgkin's lymphoma Aug-23
30 Thymic neoplasms Aug-23

BONE AND SOFT TISSUE

Exam
S. No. Topic
Date(s)
May-15,
Aug-23,
Describe the role of immunohistochemistry in the diagnosis of soft
1 Nov-10,
tissue sarcomas.
May-17,
Nov-
May-16,
2 Cystic lesions of bone
May-19
3 Chondrosarcoma May-15
4 Kaposi Sarcoma May-15
5 Variants of Synovial Sarcoma Nov-14
6 Prosthesis related changes in the bone Nov-14
7 Describe the pathology of cartilaginous tumours Nov-14
Discuss the differential diagnosis and immunohistochemistry
8 May-14
findings in malignant spindle cell tumors of soft tissue
9 Role of IHC in the diagnosis of spindle cell lesions of soft tissue May-18
Nov-13,
10 Paget’s disease of bone May-22,
Nov-21
Classify bone tumors. Etiopathogenesis, morphology, molecular
11 Nov-15
genetics of osteosarcoma
12 Discuss benign osseous lesions of intramedullary origin May-18
13 Parosteal osteosarcoma May-17
Nov-13,
14 Liposarcoma
Nov-16
Nov-13,
Describe the classification, morphology, diagnosis, and its pitfalls in
15 Nov-22,
the soft tissue sarcomas of childhood
Nov-17
Discuss about differential diagnosis and lab diagnosis of small round
16 May-13
cell tumors of the bone
May-13,
17 Etiopathogenesis of Rheumatoid Arthritis
Nov-21
18 Recent concepts in degenerative joint disease Nov-17
Nov-12,
19 Discuss in detail Giant cell Lesions of Bone. Nov-20,
Nov-22
20 Interpretation of synovial biopsy Nov-18
21 Inflammatory myofibroblastic tumor Nov-12
22 Granulosa cell tumor May-12
23 Chordoma Nov-19
24 X-linked muscular dystrophies May-18
25 Myopathies Nov-10
26 Rhabdomyosarcomas May-19
27 Sclerosing epithelial fibrosarcoma Nov-17
28 Giant cell Lesions of soft tissue Nov-17
29 Post-operative spindle cell nodule Nov-16
30 Discuss the role of EM in the diagnosis of tumors of soft tissue Nov-16
31 Myxoid tumors of soft tissue Nov-15
32 Panniculitis Nov-18
33 Discuss the various pseudosarcomatous lesions of soft tissue Nov-18
34 Reactive pseudosarcomatous proliferations May-18
Nov-18,
35 Interpretation of synovial biopsy
Nov-22
36 Ewings sarcoma Nov-18
37 Gout Nov-19
Nov-19,
38 Cartilage forming tumors of bone
Nov-20
39 Fibrous dysplasia of bone May-20
40 Solitary fibrous tumor Nov-20
41 Epithelioid soft tissue sarcoma Nov-20
42 Familial histiocytic proliferative disorders Nov-20
43 Non inflammatory non neoplastic lesions of bone Aug-22
44 Clear cell sarcoma of tendons and aponeurosis Aug-22
45 MPNST Aug-22
46 Giant cell Lesions of jaw Aug-23
47 Plexiform neurofibroma Aug-23
48 Bone tumors of childhood Aug-23
CENTRAL NERVOUS SYSTEM AND EYE
Exam
S. No. Topic
Date(s)
May-15,
1 Dysembryoblastic Neuroepithelial tumor
May-16
Classify tumours of CNS. Discuss the pathology of posterior cranial
2 May-17
fossa tumours
3 Childhood CNS tumours Nov-18
May-15,
4 Medulloblastoma Nov-18,
Nov-19
Nov-17,
5 Pathogenesis and pathology of Retinoblastoma
Nov-16
6 Chromophobe adenoma May-19
Nov-14,
7 Orbital inflammatory pseudotumours Nov-20,
Nov-22
Nov-14,
8 Morphology of the brain in Alzheimer’s disease May-18,
May-20
9 Desmoplastic infantile astrocytoma May-14
10 Types of astrocytoma May-19
11 Duchenne muscular dystrophy May-14
Nov-15,
12 Pathogenesis and pathology of muscular dystrophy
Nov-21
13 Diseases of neuromuscular junction Nov-16
14 Pituitary adenoma May-14
Nov-13,
Discuss the pathogenesis and morphological changes seen in
15 Nov-22,
Alzheimer’s disease.
Aug-23
16 Primary CNS lymphoma Nov-13
17 Genetics and morphology of Retinoblastoma Nov-13
18 Discuss demyelinating diseases Nov-13
19 Inflammatory neuropathies Nov-19
20 Myasthenia gravis Nov-15
21 Gliomesenchymal tumors May-13
22 Role of histochemistry in muscle biopsy interpretation May-13
23 Interpretation of muscle biopsies Nov-19
Nov-12,
24 Muscular dystrophy, Myotonic Dystrophy
Nov-22
25 Prognostic factors associated with malignant melanoma of the uvea Nov-12
26 WHO criteria for stratification of Meningiomas Nov-12
27 Neuroendocrine tumours May-12
28 Types of Ependymomas Nov-11
29 Neurofibromatosis May-19
30 Grading of meningioma Aug-23
31 Embryonal brain tumors Nov-21