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Extraction

The document consists of a series of multiple-choice questions related to extraction processes, drug properties, and preparation methods in pharmacology. It covers various topics such as laws of extraction, effects of temperature and particle size, and different extraction techniques like maceration and percolation. Additionally, it includes questions about the properties and classifications of drug formulations and their suitable applications.
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0% found this document useful (0 votes)
7 views7 pages

Extraction

The document consists of a series of multiple-choice questions related to extraction processes, drug properties, and preparation methods in pharmacology. It covers various topics such as laws of extraction, effects of temperature and particle size, and different extraction techniques like maceration and percolation. Additionally, it includes questions about the properties and classifications of drug formulations and their suitable applications.
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

1._______________ Law is followed during extraction process.

( b )
(a) Stokes Law (b) Mass Transfer (c) Darcy Index (d) Extraction Value Law

2. Prolonged size reduction may lead to____________of the constituents. ( c )

(a) Hydrolysis (b) Oxidation (c) Decomposition (d) Dead space


3. Drugs mostly are ___________in dry state ( b )

(a) Finer (b) Porous (c) Crystallize (d) Amorphous


4. ___________in temperature enhances penetration of solvent during extraction process ( a )
(a) Increases (b) Decrease (c) Regular Fluctuation (d) Irregular Fluctuation

5. Diffusion Coefficients is _______________ to absolute temperature and proportional


to___________of the solvent. ( c )
(a) Not Proportional, Density (b) Inversely proportional, Density
(c) Proportional, Density (d) Proportional, Boiling Point

6. Water ____________Hydrolysis of the drug Constituents. ( c )


(a) Retards (b) Fluctuates (c) Promotes (d) Decelerates

7. Flow of Solvents through drug is ( b )


(a) Clarification (b) Percolation (c) Hydration (d) Dehydration

8. Alcohol Strength is not affected in ( c )


(a) Maceration (b) Clarification (c) Reserve percolation (d) Percolation

9. The Last treatment of the drug with the solvent before it is discharged is done with the fresh
solvent entering the system. The process takes place on___________ ( c )
(a) Podbielnaik Extraction (b) Reserve Extraction
(c) Multiple Extraction (d) None of these

10. Vapor of the solvent in the extraction flask rises through the extraction chamber takes
Place in ___________________ ( c )
(a) Centrifugal Extraction (b) Podbielnaik extraction
(c) Soxhelet Extraction (d) Vertical tube extraction

“Education is the most powerful weapon


11. _____________ is the residue of the drug after extraction. ( b )
which
(a) Resinous you
Slime (b)can
Marcuse to change
(c) Menstrum the world.”
(d) Precipitant

12. Concentration infusion is a product of _________________ ( d )


(a) Sublimation (b) Crystallization (c) Vacuum Drying (d) Extraction

13. Standardized Crude extracts are called ______________ ( b )


(a) I.P. Extracts (b) Galenicals (c) Pharmacopoeial Extracts (d) Reference standards

14. The suspension of the drug in the solvent is made in _____________ ( c )


(a) Percolation (b) Extraction (c) Maceration (d) Dilution

15. The process of preliminary uniform moistening of the raw material with the menstrum is
called _____________ ( b )
(a) Preliminary treatment (b) Imbibition (c) Soaking (d) Menstrum Treatment

16. Reserve percolation is suitable for__________________ ( c )


(a) Aqueous (b) Crude Extracts (c) Alcohol-Water Mixture (d) Resins

17. Combination of maceration and percolation takes place in ______________ ( b )


(a) Percolation maceration method (b) Cover and Run Method
(c) Resin Extraction (d) Non-Polar Extraction

18. Maceration is suitable for ________________ Materials ( b )


(a) Unorganized (b) Organized (c) Crude Extracts (d) Fibers.

19. Addition of _________________ in the menstrum enhances extraction. ( a )


(a) Surfactants (b) Humectants (c) Thickening Agents (d) Opacifiers

20. Hot Maceration done by treating the drug in a closed environment is known as ( b )
(a) Clarification (b) Digestion (c) Isolation (d) Defatting

21.____________ are also known as Galenicals. ( a )


(a) Crude Extracts (b) Menstrum (c) Formulation (d) Quantity

22. ____________is not suitable for maceration. ( c )


(a) Correspondence (b) Fine powder (c) Powder (d) Graded powder

23._______________ May be assisted in extraction by Shaking. ( a )


(a) Diffusion (b) Dehydration (c) Vaporization (d) Hydrolysis

24. ___________ is used for concentrated infusion which contains volatile oils. ( d )
(a) Size Reduction (b) Maceration (c) Extraction (d) Double maceration

“I did then what I knew how to do. Now


25. __________________
that is preparedbetter,
I know by Double Maceration.
I do better.” ( a )
(a) Opium Tincture (b) Digitalis (c) Tolu Balsm (d) Lemon Graze

26. Packing of crude drug in a column takes place in ( d )


(a) Maceration (b) Analysis (c) Soarting (d) Percolation

27. Preliminary Moistening drug by the solvent helps to __________ air. ( a )


(a) Displaces (b) Pressurizes (c) Penetrates (d) Expands

28. Filter paper of the packed column _______________ disturbances of the packed
column. ( c )
(a) Aggravates (b) Corrodes (c) Prevents (d) Levels

29. ____________ Percolator is best suitable for Selling Raw Materials. ( a )


(a) Conical (b) Cylindrical (c) Hexagonal (d) Pyremidical

30. Liquid extracts are _____________ preparations than tinctures. ( a )


(a) More Concentrated (b) Less Concentrated (c) Dry (d) None of these

31. ________________ is best suitable for alcohol extracts. ( c )


(a) Percolation (b) Maceration (c) Reserved Percolation (d) All

32. Decreases in particle size ______________ Extraction. ( a )


(a) Enhances (b) Decreases (c) Disturbs (d) Produces

33.________________ of the solvent influences Extraction. ( a )


(a) Density (b) Total Ash Valve (c) Refractive Index (d) Hydration

34. Particle size distribution should be ________________ to achieve adequate permeability


of the power packing for extraction. ( b )
(a) Wide (b) Sharpened (c) Narrow (d) Equal

35. ____________ Prevents degradation of the enzyme action in aqueous extraction ( d )


(a) Water (b) Syrup (c) Anise (d) Alcohol

36.____________ is used for extraction of active principles from spices, ginger,


Oleoresin etc. ( b )
(a) Water (b) Acetone (c) Glycol (d) Sorbitol
37.____________ is present in Soxhelet apparatus. ( c )
(a) Pinholes (b) Knurling (c) Thimble (d) Edge Sealing

38. _____________ assists the penetration of the solvent in to the drug kept in the
soxhelet apparatus. ( a )
(a) Siphoning (b) Hydration (c) Humidification (d) Vacuuming

“Try not to become a man of success. Rather


39._________________ is a process of Expression. ( d )
become a man of value.”
(a) Vaporization (b) Siphoning (c) Permeation (d) Hydraulic Pressing

40. Process of extracting perfume oils is called____________ ( c )


(a) Periodation (b) Iodination (c) Effleurage (d) Vaporisaation

41. Separation of the active constituents from the crude drug is desirable due to which of
the following reason ? ( g )
(a) Potency is more readily controlled.
(b) Deterioration Eg:Enzyme action is Diminished.
(c)Preparation of the drug are more easily formulated, more stable,more palatable,
more elegant.
(d) Smaller bulk facilities storage and transport
(e) Injection of the crude material may be undesirable or Dangerous.
(f) Tabletting or Formation of other unit dosage form may not be possible with the
Crude materials.
(g) All the Above.
42. In one of the extraction processes the crude drug particles are taken in a closed vessel along
with the solvent with occasional shaking for few days. This is known as ( b )
(a) Percolation (b) Maceration (c) Infusion (d) Decoction

43. An Ideal process of tea preparation ( a )


(a) Infusion (b) Decoction (c) Digestion (d) Maceration

44. Percolation process of extraction excludes ( b )


(a) Organized Drugs (b) Unorganized Drugs (c) Soft Drugs (d) Woody Drugs

45. Decoction process of extraction is taken for ( b )


(a) Soft Drug (b) Woody Drug (c) Organized Drug (d) Unorganized Drug

46. The Infusion process of extraction is used for ( b )


(a) Hard Woody Drug (b) Soft Spongy Drug (c) Volatile Oil (d) All

47. To increase the stability of tinctures --------------------- is added ( a )


(a) Glycerin (b) Water (c) Sugar (d) cystine

48. Fluid extracts are also known as ( d )


(a) Menstrum (b) Extracted Menstrum (c) 100% Tincture (d) 80% Tincture

49. The term Percolation is also known as ( a )


(a) Lixiviation (b) Softening (c) Reserved Percolation (d) Expression

“Success is getting what you


50. Tinctures Are want, happiness is wanting what ( e )
you get”
(a) Are made by direct solution of a volatile oil
(b) Represent 100gms of drug of 100ml of finished tinctures
(c) Are aqueous solution of active constituents of drugs.
(d) Are sweetened, flavoured aqueous alcoholic solution of drug.
(e) None of the above
51. The following dosage forms are normally prepared by maceration (or) percolation
Of source product ( c )
(a) Spirits (b) Lotions (c) Tinctures (d) Waters

52. Fluid Extracts are liquid dosage forms containing in each ml the active constituents
of: ( a )

(a) 1gm of crude drug (b) 2gm of crude drug


(c) 5gm of crude drug (d) 10gm of crude drug

53. These are liquid extracts of vegetable drugs containing alcohol as a solvent,
a preservative (or) both ( d )

(a) Elixirs (b) Sprits (c) Tinctures (d) Fluid Extracts

54. These are alcoholic (or) Hydroalcoholic solutions of chemicals or soluble constituents of
crude drugs ( c )

(a) Elixirs (b) Sprits (c) Tinctures (d) Fluid Extracts

55. Alcoholic or Hydroalcoholic solutions of volatile substances containing 50 to 90% of


alcohol are known as ( b )

(a) Elixirs (b) Sprits (c) Tinctures (d) Fluid Extracts

56. The following is the extraction process in which the desired constituents are dissolved from
granulated or powdered drug by the controlled descent of a suitable solvent through a columnof
the drug ( b )
(a) Agitation (b) Percolation (c) Soxhlet Extraction (d) Decoction

57. The are alcoholic liquids usually containing, in low concentrations, the active principles of
crude drugs. They are generally prepared by maceration or percolation or obtained by dilution of
the corresponding liquid or soft extracts ( b )
(a) Liquid Extracts (b) Tinctures (c) Infusions (d) Oxymels

“Failure is the condiment that gives success its flavor.”


58. These are preparations of acetic acid and honey and are used as solvents or vehicles for
crude drugs ( d )

(a) Liquid Extracts (b) Tinctures (c) Infusions (d) Oxymels

59. Belladonna tincture is prepared by __________ ( b )


(a) Maceration (b) Percolation (c) Infusions (d) Decoction
60. Store in a Cool Place Means ( a )
(a) 10-150C (b) 10-250C (c) 10-350C (d) 10-450C

61. The continuous heat extraction of fixed oils is known as ( d )


(a) Maceration (b) Percolation (c) Infusions (d) Soxhelation

62. Liquorice powder is used as ( c )


(a) Astringent (b) Expectorant (c) Adsorbent (d) All the above

[Link] test measures the liquefaction time of rectal suppositories? ( b )


(a) Melting range test (b) softening time test (c) dissolution test (d) All

[Link] the example of medicated spirit is ( a )


(a) Aromatic ammonia spirit (b) compound cardamom spirit
(b) Compound lemon spirit (d) compound orange spirit

65. Which of the following is not quality of suppository base? ( a )


(a) Broad melting test (b) Inert
(c) Non- irritating (d) Have melting and emulsifying properties

66. Which method is not used for the preparation of suppositories? ( d )


(a) Hand rolling (b) Compression (c) Fusion method (d) Levigation

67. Rectal Suppositories intended for adult use usually weigh approximately: ( b )
(a) 1gm (b) 2gm (c) 3gm (d) 4gm

68.A satisfactory suppository base must meet all the following criteria except: ( d )
(a) It should have the narrow melting range (b) It should be Non- irritating
(c) It should be inert (d) It should melt below 300c
69. Cocoa butter exhibits all the properties except: ( c )
(a) It is a mixture of glycosides (b) It is a polymorph
(c) It is soluble in water (d) It is useful in formulating rectal suppositories

70. In the fusion method of making cocoa butter suppositories, which of the
following substances is most likely to be used for lubricating the mould? ( a )
(a) Mineral oil (b) propylene glycol (c) Stearic acid (d) Magnesium silicate

“Education
71. Witepsol is notbase
is a suppository thebelonging
filling to ofthe
a class
pail,ofbut the lighting of (a c )
(a) Oleaginous (b) Hydrophilic (c) fire.”
Emulsifying (d) Natural

72. An example of aqueous suppository base is ( b )


(a) Theobroma oil (b) Macrogal (c) Massupol (d) Masse Esternum

73. Higher Displacement value of a drug indicates its (d )


(a) Lightness (b) Fluffiness (c) Bulkiness (d) Heaviness
74. In Hydrous Wool Fat the proportion of wool fat and water is ( b )
(a) 1:1 (b) 7:3 (c) 4:1 (d)9:1

75. How many number of suppositories should be taken for disintegration test ( a )
(a) 3 (b) 6 (c) 9 (d) 18

76. Suppository bases used are those having melting point in the range of ( c )
(a) 20-250c (b) 43-500c (c) 37-400c (d) 15-180

77. In the fusion method of making cocoa butter suppositories, which substance is most likely
to be used to lubricate the mould? ( a )
(a) Mineral Oil (b) Propylene glycol (c) Cetyl Alcohol (d) Stearic Acid

78. Glycerine suppositories contain 92% glycerine and are solidified by the use of ( c )
(a)White wax (b) Stearic acid (c) Sodium strearate (d) PEG 4000

79. The Suppository base cocoa butter exhibits all BUT the following properties? ( c )
(a) Immiscible body fluids
(b) Exhibits Polymorphism
(c) Gives better release rates for lipophilic drugs
(d) Has Ideal Melting Characteristics

80. ___________ as suppository base consists mixed triglycerides of oleic, palmitic, and
stearic acids, which melts at 34-350C and congeal at 20 or less 0C. ( c )

(a) Soap Glycerine (b) Glycerinated gelatin (c) Cocoa butter (d) All the above

81. An example for a suppository base belongs to non-greasy type is ( b )


(a) Soap Glycerine (b) Glycerinated gelatin (c) Cocoa butter (d) All the above

82 _________________are semisolid dosge forms intended to insert into body orifices like
vagina, rectum where they melt and release their medication and exert local or systematic
action.

“Keep your face to the sunshine and you can


never see the shadow.”

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