Rajiv Gandhi University of Health Sciences, Karnataka
III Year [Link]. (MLT) Degree Examination - 28-Aug-2020
Time: Three Hours Max. Marks: 80 Marks
PATHOLOGY – PAPER III (RS-3)
Q.P. CODE: 3161
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. Write a note on different blood grouping systems. Discuss the different methods to perform blood
grouping and typing.
2. Discuss culture of peripheral blood lymphocytes. Add a note on the different banding techniques.
3. Discuss methods of collection, fixation, processing and staining of cytological specimens.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. What is Du? How it is detected?
5. List the subgroups of Blood group A. How are they detected and confirmed?
6. What are the different blood collection systems available?
7. Uses and advantages of FNAC
8. Haemolytic disease of newborn
9. Nomenclature of chromosomes
10. Crossmatching of blood
11. List any three donor adverse reactions and their preventive measures.
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. Sex chromatin identification
13. Name five normal components of cervical smear.
14. Autologous blood transfusion
15. Name any three minor blood group systems.
16. Cryoprecipitate
17. MGG stain
18. Bombay blood group
19. Direct Coomb’s test
20. List three reasons for donor deferral.
21. Chromosomes in cancer
22. Karyopynotic index
23. List three fixatives used in cytology.
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Rajiv Gandhi University of Health Sciences, Karnataka
III Year [Link]. (M.L.T) Degree Examination – 20-May-2023
Time: Three Hours Max. Marks: 100 Marks
PATHOLOGY – III (RS-4)
Q.P. CODE: 3284
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Second Question Choice) 2 x 10 = 20 Marks
1. Discuss principle, procedure of flow cytometry.
2. Enumerate the transfusion reactions. Discuss the process of investigating a transfusion
reaction.
OR
Discuss the process of culturing peripheral lymphocytes. Add a note on different types of
banding techniques.
SHORT ESSAYS (Question No 5 & 10 choice) 10 x 5 = 50 Marks
3. Papanicolaou staining.
4. Rh blood group system.
5. Cytologic criteria for malignancy.
OR
Quality control in cytology laboratory.
6. Indications for platelet transfusions. How do you store platelets?
7. Write histology and normal cytology of respiratory tract.
8. Chromosomal abnormalities in cancer.
9. Hemolytic disease of the newborn.
10. What is Barr Body? Add a note on different staining methods used.
OR
Bombay blood group.
11. Describe the method of processing sputum for Cytologic examination.
12. Plasmapheresis.
SHORT ANSWER 10 x 3 = 30 Marks
13. FNAC of breast.
14. Cytology of carcinoma of cervix.
15. Oncogenes.
16. Significance of HLA antigens.
17. Du test.
18. Three anticoagulants used in blood bank.
19. Spray fixatives.
20. Use and care of microscope.
21. Triploidy.
22. Colchicines.
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Rajiv Gandhi University of Health Sciences, Karnataka
III Year [Link]. (MLT) Degree Examination - 04-Aug-2021
Time: Three Hours Max. Marks: 80 Marks
PATHOLOGY – PAPER III (RS-3)
Q.P. CODE: 3161
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. Describe the principle and staining technique of PAP Stain.
2. Enumerate the types of structural abnormalities in chromosomes with examples.
3. Write about different components of blood and explain preparation of platelet concentrates.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. Stains used for chromosome study
5. Coomb’s test
6. ABO blood group system
7. Transfusion reactions
8. Flow cytometry
9. Techniques of collection of specimen for cervical study
10. Cytological fixatives
11. Du testing and its significance
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. Cryoprecipitate
13. Identification of sex chromatin
14. Preparation of Harris haematoxylin
15. Triploidy
16. Cross matching in blood bank
17. Use of microscope
18. Maturation index
19. Name three transfusion transmitted infections.
20. Sputum examination for AFB
21. Inverted microscope
22. Bombay blood group
23. Method of collection of urine for cytology
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Rajiv Gandhi University of Health Sciences, Karnataka
III Year [Link]. (M.L.T) Degree Examination – 16-Dec-2022
Time: Three Hours Max. Marks: 100 Marks
PATHOLOGY – III (RS-4)
Q.P. CODE: 3284
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Second Question Choice) 2 x 10 = 20 Marks
1. What is Fine needle aspiration cytology? Discuss the procedure, advantages and
disadvantages of FNAC over biopsy.
2. Define a Karyotype. Discuss the procedure of Karyotyping using peripheral blood
lymphocytes.
OR
Discuss various selection criteria used while selecting a donor for blood donation.
SHORT ESSAYS (Question No 5 & 10 choice) 10 x 5 = 50 Marks
3. Anatomy, histology and normal cytology of female genital tract.
4. Anticoagulants used in blood banking.
5. Autologous transfusion.
OR
Quality control in blood bank.
6. Preservation of immortalized cell lines.
7. Cryoprecipitate.
8. Demonstration of Barr body in buccal smear.
9. Difference between benign and malignant tumours.
10. Flow cytometry.
OR
May Grunwald Geimsa staining method.
11. Oncogenes.
12. Coomb’s test.
SHORT ANSWER 10 x 3 = 30 Marks
13. List three fixatives used in cytology.
14. Name three minor blood group systems.
15. Name three applications of immunohistochemistry.
16. Inverted microscope.
17. Normal cytology in urine sediment.
18. Mention three transfusion transmitted infections.
19. Maturation index.
20. Liquid based cytology.
21. Exfoliative cytology.
22. Histology of salivary glands.
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Rajiv Gandhi University of Health Sciences, Karnataka
III Year [Link]. (MLT) Degree Examination - 16-Dec-2020
Time: Three Hours Max. Marks: 80 Marks
PATHOLOGY – PAPER III (RS-3)
Q.P. CODE: 3161
Your answers should be specific to the questions asked
Draw neat, labeled diagrams wherever necessary
LONG ESSAY (Any Two) 2 x 10 = 20 Marks
1. Describe in detail the procedure of FNAC. List the advantages, disadvantages and limitations of
FNAC.
2. Classify adverse transfusion reactions. Write in detail sample collection and work up of transfusion
reactions.
3. Describe the Sample collection of CSF for lab investigation. Describe cell counting of CSF Samples.
List the Variations of CSF findings in Tuberculous and Pyogenic.
SHORT ESSAY (Any Six) 6 x 5 = 30 Marks
4. Liquid based cytology
5. Describe quality control parameters of packed Red Blood Cells.
6. Applications of Immunohistochemistry
7. Describe the cytological findings in malignant thyroid lesions.
8. Detection of subgroups of A and B blood grouping systems
9. Structural chromosomal aberrations
10. Describe progressive and regressive stains.
11. Procedure for Cell block preparation and advantages
SHORT ANWERS (Any Ten) 10 x 3 = 30 Marks
12. List the government authorities of blood bank administration.
13. List 3 advantages of computer software in blood bank.
14. Mention 2 indications of exchange transfusion.
15. What are the pre-requisites of autologous transfusion?
16. Mention 4 Thyroid neoplasms.
17. Down’s Syndrome
18. Mention 2 normal Maturation indices.
19. Mention 4 special types of microscopes.
20. List 2 advantages of Leuco depleted blood products.
21. Mention 4 equipments used in blood component separation Laboratory.
22. Mention 4 indications of flow cytometry.
23. What the advantages of karyotyping?
*****
Rajiv Gandhi University of Health Sciences, Karnataka
Third Year [Link]. Medical Laboratory Technology Degree Examination – 31-Oct-
2025
Time: Three Hours Max. Marks: 100 Marks
PATHOLOGY – III (RS-4)
Q.P. CODE: 3284
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Second Question Choice) 2 x 10 = 20 Marks
1. Describe the methods of collection of specimens from respiratory tract for cytological
examination along with the preparation and staining of smears
2. Describe the principle of immunohistochemistry and list five marker and its significances
OR
Enumerate various transfusion reaction. Explain the screening of blood for infective material
SHORT ESSAYS (Question No 5 & 10 choice) 10 x 5 = 50 Marks
3. Hormonal cytology of female genital tract and cytological indices
4. Coomb’s test
5. Laminar air flow equipment
OR
Quality control in blood bank
6. May Grunwald Geimsa stain
7. Explain about blood containers and anticoagulants used in blood bank
8. Describe the preparation of 5% cell suspension. Add a note on Cross
matching
9. Component therapy in blood blank
10. Histology and physiology of thyroid gland
OR
Cytology of Endometrium
11. Oncogenes
12. Explain different methods of blood grouping
SHORT ANSWER 10 x 3 = 30 Marks
13. Barr body
14. Anatomy of lymph nodes
15. Mention three advantages of FNAC
16. Bombay blood group
17. Use and care of microscope
18. Maturation index
19. List three difference between Transudate and exudate
20. Donor selection criteria
21. Peripheral smear
22. What is flow cytometry?
Rajiv Gandhi University of Health Sciences, Karnataka
*****
Rajiv Gandhi University of Health Sciences, Karnataka
Third Year [Link]. Medical Laboratory Technology Degree Examination – 27-Nov-
2024
Time: Three Hours Max. Marks: 100 Marks
PATHOLOGY – III (RS-4)
Q.P. CODE: 3284
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Second Question Choice) 2 x 10 = 20 Marks
1. Discuss about anatomy, histology and physiology of female genital tract
2. Enumerate different blood group system. Add a note on ABO blood group and its grouping
methods.
OR
Describe in detail the procedure for FNAC. Add a note on spray fixative and limitations of
FNAC
SHORT ESSAYS (Question No 5 & 10 choice) 10 x 5 = 50 Marks
3. Fresh Frozen Plasma
4. Rapid pap stain
5. Write on hemolytic disease of newborn
OR
Explain the anatomy and physiology of salivary glands
6. Cross matching techniques
7. Transfusion reactions and workup
8. Discuss indications of different blood components.
9. Rh system
10. Write a note on preservation of immortalized cell line
OR
Cytology of effusions in malignant conditions
11. Carbon dioxide incubator
12. Write a note on laminar air flow equipment
SHORT ANSWER 10 x 3 = 30 Marks
13. Types of microscope
14. Mention Karyotypic and Phenotypic abnormalities of turners syndrome
15. Indication of whole blood transfusion
16. Composition of anticoagulants used in blood bank
17. Draw neat labelled diagram of normal Pap smear
18. G-banding
19. Principle of immunocytochemistry
20. Sub groups of A and B
21. Normal cell structure
22. Organization of blood bank
Rajiv Gandhi University of Health Sciences, Karnataka
*****
Rajiv Gandhi University of Health Sciences, Karnataka
III Year [Link]. (M.L.T) Degree Examination – 05-Jun-2024
Time: Three Hours Max. Marks: 100 Marks
PATHOLOGY – III (RS-4)
Q.P. CODE: 3284
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Second Question Choice) 2 x 10 = 20 Marks
1. Write in detail about blood bank organisation, procedures and quality control.
2. Discuss about characterization of human chromosomes by various banding techniques.
OR
Enumerate transfusion reactions and add a note on transfusion reaction.
SHORT ESSAYS (Question No 5 & 10 choice) 10 x 5 = 50 Marks
3. Cytologic criteria of malignancy.
4. Cell Block preparation.
5. Indirect Coomb’s test.
OR
Cytology of Endometrium.
6. Cytology of respiratory tract lesions.
7. Image analysis.
8. Inverted microscope.
9. Preservation of immortalized cell lines.
10. Cross matching techniques.
OR
Applications of Immuno cytochemistry.
11. Minor Blood group systems.
12. Autologous transfusion.
SHORT ANSWER 10 x 3 = 30 Marks
13. Name three fixatives used in cytology.
14. Principle of Papanicolaou stain.
15. Shorr stain.
16. Hormonal cytological indices.
17. Cytology of CSF.
18. Three advantages of fine needle aspiration cytology.
19. Uses of cryoprecipitate.
20. Principle of flow cytometry.
21. Sex chromatin.
22. Platelet concentrate.
*****
Rajiv Gandhi University of Health Sciences, Karnataka
III Year [Link]. (M.L.T) Degree Examination – 22-May-2025
Time: Three Hours Max. Marks: 100 Marks
PATHOLOGY – III (RS-4)
Q.P. CODE: 3284
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Second Question Choice) 2 x 10 = 20 Marks
1. List blood components. Describe the method of preparation of platelet concentrate. Add a
note on storage of platelets.
2. Mention the stains used in cytology. Write the principle and preparation and staining method
of may grunwald Geimsa Stain.
OR
Discuss the principle and equipment used in flow cytometry. Add a note on its uses in the
diagnosis.
SHORT ESSAYS (Question No 5 & 10 choice) 10 x 5 = 50 Marks
3. Fresh frozen plasma.
4. Advantages and disadvantages of FNAC.
5. ABO blood group system.
OR
Cell Block preparation.
6. Cytological fixatives.
7. Quality control in blood bank.
8. Tests for transfusion transmitted infections.
9. Histology and normal cytology of salivary gland.
10. Principle and use of immunohistochemistry.
OR
Blood containers, anticoagulants and storage of blood and blood components.
11. Various banding techniques.
12. Oncogenes.
SHORT ANSWER 10 x 3 = 30 Marks
13. List three infections diagnosed in PAP smear.
14. List three transfusion transmitted diseases.
15. Colchicines.
16. Normal cell structure.
17. Write three differences between benign and malignant cells.
18. Laminar flow equipment.
19. Major cross matching.
20. Sub groups of A & B
21. Schorr stain.
22. Normal cytology of endometrium.
*****
Rajiv Gandhi University of Health Sciences, Karnataka
III Year [Link]. (M.L.T) Degree Examination – 29-Nov-2023
Time: Three Hours Max. Marks: 100 Marks
PATHOLOGY – III (RS-4)
Q.P. CODE: 3284
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Second Question Choice) 2 x 10 = 20 Marks
1. Give an account of cervical cytology screening for malignant and non-malignant conditions.
Add a note on radiation changes.
2. Write about blood components preparation, storage and uses of each of them.
OR
Discuss methods of Karyotypic analysis.
SHORT ESSAYS (Question No 5 & 10 choice) 10 x 5 = 50 Marks
3. Procedure of Papanicolaou’s stain.
4. Cytology of cerebrospinal fluid.
5. Urine cytology.
OR
Fine needle aspiration cytology of salivary glands.
6. Laminar air flow equipment.
7. Direct and indirect Coomb’s test.
8. Chromosomes in neoplasia.
9. HLA antigens.
10. Methods of bleeding donors.
OR
Transfusion transmitted diseases.
11. Investigation of transfusion reaction.
12. Rh blood group system.
SHORT ANSWER 10 x 3 = 30 Marks
13. Fixatives used in cytology.
14. May-Grunwald Giemsa stain.
15. Three uses of flow cytometry.
16. Three applications of Immuno cytochemistry.
17. Name three enzymes used in tissue culture.
18. Uses of inverted microscope.
19. Bombay blood group.
20. Duffy blood group system.
21. Three causes of mismatched blood transfusion.
22. Hormonal cytology
*****
Rajiv Gandhi University of Health Sciences, Karnataka
Third Year [Link]. Medical Laboratory Technology Degree Examination – 11-May-
2026
Time: Three Hours Max. Marks: 100
PATHOLOGY – III (RS-4)
Q.P. CODE: 3284
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Second Question Choice) 2 x 10 = 20 Marks
1. Describe the normal cytology of female genital tract. Add a note on the Bethesda system
2. Enumerate blood transfusion reactions. Write on investigations of transfusion reactions
OR
Describe the methods of compatibility testing
SHORT ESSAYS (Question No 5 & 10 choice) 10 x 5 = 50 Marks
3. Cytology of squamous cell carcinoma of cervix
4. Platelet Apheresis Technique
5. Haemolytic disease of newborn
OR
List the subgroups of blood group A. how are they detected and confirmed?
6. Automation in cyctology
7. Principle of Immuno cytochemistry
8. What is Du? How it is detected?
9. Rapid Pap stain
10. Describe cytology of effusions in malignant and non-malignant conditions
OR
Image analysis
11. Broncho alveolar lavage
12. Oncogenes
SHORT ANSWER 10 x 3 = 30 Marks
13. Bombay blood group
14. Write three anti-coagulants used in blood bank
15. Normal histology of thyroid gland
16. List four common sites of FNAC
17. Cryoprecipitate
18. What is dry and wet fixation?
19. CSF in pyogenic meningitis
20. List three transfusion transmitted diseases
21. Fresh frozen plasma
22. Importance of Rh system
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