BZ Tnhesitene § Vevriation - #6 Inheritance . Percecs by which characters aw from ponents fo paging He Voniaton > Degeve by which progeny euftern from ther prune - ae Menoleliou. Yenetics — f doope Meal: alton oy fle — Pustian monk - experi menteal on — Pisum sativum C Garcon pee) - = pen i850- 1°63 he per formacl enp: = publicheel pope in 1860 ° = Rearow for gucceek 5 7) Application of stat € maths ii] honge sampling sire- ii Recorded observations wifreut mavipulstior : 4rutlte - iv) Aubtiahesl otata in oe journal: — Bub at that tire he Facer! cuticism - — Fapeu Aesiscovercel in 1900 by — Cowen, de vvie, Tschewmak: — Resrono tov selectivg, pew plot — i] Gary to grow ii) Gieenual iit) sort ger spew ° iv) Shows mony condouting characters: — Ft pak contsatting characters ore Chorrackenn Dorunant | Receive (0 Plank Haight Tell 6 elivorty Cit) oe Yellow CYY) Ureene Lyy)(Q Seeceh Wu ~ . Round RR) cominkled taf @ Seeal Lhope ® Poo cwlowe Greencu) | Yelle) © pret arape Iofleteby | anh © Flower clo Purple @P) ~~ @ Power pation | Reintengy | TOMER iD single pair Js confeantiry Pavented gC OF x @ Phurclype 7: Teh x Daan Genotype | ak x te Gameter : @ x © Fr gen : Heteroxygou> toll: ating Bs Tt x Tt - Z > Gametes } ‘ep © ® fo gent : © © @y tr | te @©| te tt Phenotypic vatio + 3 :! (yrokypic watio. | 2:25] my de Mendel’'s First haw : © kw of Dominance +ere VW] Characten ave contrllec! by atisowte units callest Factors: ii] Fachors occur in paits iii] The teait which is erepresserl in Fi ger is Dominant & ore whith is mouked is Paced ve se Baceptiow fo law dp Deminanle - erp pears . ex: Mirabilis jalapa [Flower colour} Phenetyte — Reet x white tenor: - SR t Qameter — 6 6 — 7 f, gen &} Pink Prpwere et = he x Roo ; - on — ~ >>) Li » AQ@a @® @® ee noes ioe as Ro« ' ; fage — & RR] Ae | ae & Genotypic + both alleles eoeprend equal K Phenotypic < genotigpic satio =7) EO ton two adleles tor a gene but Population hao reulliple alleles for a alnylh gore’ Reson could be wmuseibinns —— . Git 7) a u 4 Mendel’s Second law - + Law of Sepegation [lew of punty of Gamefen’} dy agene rut segregate / separade, fo “> (ow in ives * 4 mating of £, prego matin of F pray with Pp + with yp poner L Fo Find out genotype of progery " i + “DEHYBRED Cross. 1 Crase bet” penents aiffexing in > pam E ens chanatrw: Eq. Fale x winked, gpmCameleon — “a Ge a Fi gan® — He: ferwrygous Round & yellow: goes fa geo’ — (puncte corre |. Phenotypic watio — : i — dt (Mendel's third baw — © Low of Enolpenclent oxrontmant | = Alleles of genes loated on aliffenont chromp2omeo atte + inelepenclant— of each other « — Exception + [Linkage | 4+ [PEEOTROPY | — when sing gore © confenls ne than on chanader / trorotpe 7 -_ —_— 2) se POLYGENTe INHERITANCE * _ when foo oF more genet contr) a character eg: Funan skin colaun & human help” We ee I I oe yu Camete»eet hesta cia Chee 4p Chromosomal Theory of Tnhexitence ~ = by Sutten & Bove - > Chromosome ow unit of inhattinee > Cruwormr Os paired - > Separation ay a pair of chovmrosome taken place, a es —= modal > Drosophila mulavoganice Coats tea > ined term Linkage & Recombination bet" none biste. Chr. of Hes0m) » Linkage > The tendency of the gener ox alleles qo qet inherited together oF not - “Poly tom LE two genet cru clowoly Lireao) i tre linkoge Is more , the terol a fo inherit togethur is_move ° Looeeky lia the ohistance Get" feve gine ee & their fenclonvy 42 Inherit togethor is less - te tr In arosepilS - sstenes for eye colours & body ) Hightty Unked 18% pacorebination ) > Genes for eye color & wing sine wow Looaely Unkeel C 39-27 oombinatte>~)) Bile charter Gene meri. ep low antsy BOL oaeaminaion : [Hoting- RAE [| XX= KY [XX=X0] aa > in humamw = > B Gee tee = Drvzophila — soma ine : 4 Haploctiploicly > Honey bees a que Female Can [Peone ¢n)| cn) Fa chreornoorn’) Cie Cia cyanate) | melouis J trifosis on x. Uia00} ay reeks Q I Genetic [mendelioun Chrmowmal — @ Down's Tumen’s etn \Co lowe sthypertricheds — [P 7 buinslvet al Haernaplulia. €g-widow & Peale. — SCA > Plea Cains in ear pina) . > ystic fbrvais > Thalaccerdce " oO (lows blindinew — pace eteaeeaea : > Ret & Green colour ayeor grey ° > occu gx in mateo € oy in femaleo « — > Shows [Criss ces \inheritance pottew : + Grand persnt> +o aaugnter to goarlion : & Haemopi lie S > Clotting factors VI / IK rt proouceel so, vmple cub leaalo to Heesling, excerively - > feo, Reyot olirazore - MN VI @) Sick coll Anowmie \ (pfretacvorie.| — Qualitative - Quanti tative - > yer te faulty — few Hb + 0.0) —> Due substitution d¢ p> two typen _ tutamic & by valine ak el position of B-chain’ &-Th: \p-Th. of Hb | = RBC tum sickle oo oe Hom @ HBB with chor + shopeot > Spanmegs eee oo ehh che 6) fe keformaice > 4 Phenglalanine a fyzosine Phen hyhonglou | ued enzyme not Pp? + Phenyla lanint — Phony PYOV!< loss of al : pi ng Moth é qucumaulates in broly in hoot & skin SS i 4F Chromosomal Disorders § - > Due to asdition ox deletion 5 chromocomes - — Reason: Non - dis}unction at anaphaue « Cenultiple of iple of batic Seteinetochore teisorey aot mo nosomy faicomy ot are aT al pee+ v. Si Male / Female Sienile sjeuile Female Male with fertnina charasteso