OBSE Notes
OBSE Notes
→ Remove it
Vaginal bleeding+loss of pregnancy symptoms+falling hCG and denies passage of fetus tissue w/ no fetus on U/S
= Anembryonic Pregnancy → follow up
RF → severe MR → forceps
Preconception
Supplementation
- Folic Acid
- ↓ risk? → 0.4mg
- m risk? → 1 mg
- ↑ risk? → 4mg (Hx of NTD)
Drugs
- A+B → Safe
- C → Benefit > Risk ? → Give it
- D+X → Unsafe
Teratogenic Viruses
→ GIVE MMR PRECONCEPTION PREVENT SAB
→ Rubella Exposure During Pregnancy?
→ Reassurance
ANC
1. First Visit? → most important in 1st visit
2. Dating
- Hx? LMP (1. Regular Cycle. 2. No Contraceptive 3. No Lactation)
EDD = Mo (Subtract 3 mo) + D (Add 7 ds)
- Ex? Symphysis → Fundus
- U/S? T1 → CRL
T2 → FL, BPD
3. T
- <20wk → Bleed? = Miscarriage
- >20wk → Bleed? = APH
- <37wk → PTL, PPROM
- >37wk → Term
4. Prenatal Diagnosis
→ Screen Tests?
- T1 → Combined Test = NT + hCG + PAPP-A
- T2 → Quadruple Test= hCG+Inhibin + Estriol+AFP
→ Positive?
→ Diagnostic Tests?
- T1 → CVS (11-14wk)
- T2 → AC (15-16wk)
Drugs
- Contraindications
- ACEi (Renal Agenesis, Oligo), Alcohol (Cardiac defect, Microcephaly, retardation)
- Blood thinner (Warfarin → nasal hypoplasia, stippled epiphyses) ABx (Tetracycline →
Dental Enamel Hypoplasia)
- Chloroquine (Choeioretinitis, Deafness)
- DES (vaginal adenoCa, Uterine Malformations), Deafness (Retinoids → give OCP if she takes it)
- Epilepsy (V. Acid → normal tube, facial characters, Phenytoin → cardiac defect, cleft palate digital
hypoplasia)
- Fucked in the head (Li → cardiac ‘epstein')
- Ionizing Radiation esp 8-15th wk(3% retardation, microcephaly/ 15% SAB)
- Nitrofurantoin (Last Month)
- Indications
- Amoxicillin (Safest Abx)
Amniotic Embolism = Sudden SOB, FHR Brady, DIC after ROM (during labor) → emergency C/S
VTE
- DVT Hx in pregnancy? → LMWH (Enoxaparin)
- sob, Hypoxia post c/s? → LMWH (Clexane)
hCG ↑↑↑ ↑
Ectopic = (Ampulla>Isthmus>Fimbriae>Ovary>Abdomen>Cervix)
- RF
- Hx PID mc (PID → damage cilia)
- Hx ectopic most important (recurrence? 15% if 1 Hx, 20% if 2 Hx) → Offer IVF if too many Hx
- Hx surgery tube/ovary
- Dx?
→ <20wk Pain, Amenorrhea, Bleed, +ve hCG + Palpable Adnexal Mass?
→ Stable?
→ No → Exploratory Laproscopy
→ Yes
→ TVUS
→ Adnexal Mass → Tx Ectopic
→ Intrauterine Pregnancy
→ Nondiagnostic
→ serum hCG
→ >1500 IU/L → repeat hCG + TVUS in 2ds
→ <1500 IU/L → repeat hCG in 2 ds
- Tx?
→ Stable?
→ hCG <5000, Size <3.5 cm, no fetal heart rate?
→ MTX (must be near hospital, Far? → admit)
→ hCG after 1 wk
→ Unstable, C/I MTX, Fail MTX (↑ or plateau hCG despite MTX) , hCG >5000, Size >3.5, renal?
→ Laparoscopy (Laparotomy if critically unstable)
→ Salpingectomy IF ruptured tube, >3cm
→ Salpingostomy IF unruptured, <3 cm
→ hCG weekly (follow up)
→ remain detectable after surgery?
→ MTX
SAB = Pregnancy Termination <20wkGA OR fetus weighs <500g
- ET
- T1 → chromosomal abnormalities (Trisomy 16)
- T2 → cervical incompetence
- Missed → fetal death w/o expulsion w/ closed cervix
→ RhoGAM
→ T1 → dilatation and curettage (Cx asherman ‘obliteration of cavity nxt
amenorrhea, infertility’, perforation, infection, bleed)
→ T2 → Misoprostol
- Threatened → Bleed w/ cervical closed w/o expulsion
→ RhoGAM
→ Reassurance
- Inevitable → Bleed w/ cervical open and pain w/o expulsion
→ RhoGAM
→ w/w or misoprostol
→ Heavy bleed?
→ D&C (Perforation>Bleeding, Infection, Asherman’s)
- Incomplete → Bleed w/ expulsion and open cervix
→ RhoGAM
→ w/w or misoprostol
→ Septic OR Heavy bleed?
→ D&C
- Complete → Bleed w/ expulsion and closed cervix
→ RhoGAM
→ serial hCG until it’s 0
- Missed → Incidental by USG no Heart Beat
→ w/w or misoprostol
→ Fail?
→ D&C
- Recurrent → >2 consecuitive abortions
- ET
- Fetal → Chromosomal Anomalies
- Maternal
- Uterus
- Cervical incompetence
- submuCosal fibroid
- Commonly uterine septum
- Cavity asherman’s
- Medical
- Thyroid
- DM
- PCOS
- SLE (APS)
- Thrombophilia
- Rh
- Infection → CMV, BActerial Vaginosis
- Septic → Infection Cause Misscrraige
→ IV broad Abx
→ D&C
PTL = 1. Labor (>3 contractions last >30 sec in 3 min w/ >2cm dilation OR 80% effacement) 2. <37+>20wk
- Mx
→ RF: Hx PTL, PPROM, PROM OR Multi Gestation OR Cigarettes, short Cervix, Cervix surgery, late wks
sex
→ Labor <37wk + >20wk?
→ Mother Positioning (Lateral Decubitus) w/ bed rest, fluids, O2
→ Fail (to stop contractions)?
→ No (HTN, DM, ROM, dilatation >4cm, HD, Bleed, )?
→ GA? (Tocolytics → nifedipine > indomethacin)
→ <32? →Tocolytics+Betamethasone+MgSO4+Penicillin
(MgSO4 w/ indomethacin → if expected delivery w/i 24hr = neuroprotection ‘cerebral palsy’)
→ >32? →Tocolytics+Betamethasone+Penicillin
→ >34? → Betamethasone+Penicillin
- Prevention
→ Hx of PTL
→ Yes
→ IM Progesterone
→ TVUS-cervix
→<25mm?→Cerclage (at 13-16 wk) w/ serial TVUS-CL until 24wk
→>25mm?→Serial TVUS-CL until 24wk
→ No
→ TVUS-cervix
→<25mm?→Vaginal progesterone
→N?→routine ANC
- CC → PPROM, Prematurity (killer)
→ Fetal Bradycardia?
→ Station?
→ +1, +2, +3? → Forceps
→
reduced variability
- Mg-Sulfate
- Sleep Pattern
- Opidiod
- Prematurity
- Hypoglycemia
- Fetal Hypoxia
- Cord Prolapse
Infections
GBS
- Screen? 35-37 wkGA rectovaginal culture
- Tx? IF ↓ by IV Penicillin G 4hr before V/D and if ROM on C/S
- GBS disease Hx in infant
- GBS bacteriuria
- GBS UTI
- GBS +ve 5wk prior to labor
- GBS unknown status PLUS >1:
- <27 wk
- Intrapartum Fever
- ROM for >18hr
Pox
- Hx of Pox? → give mom MMR before pregnancy
- Pox perinatal (5ds before or 2 ds after)? → give baby varicella-Zoster Ig
HSV
→ Acyclovir maximize chance of V/D
→ Labor?
→ Speculum Exam
→ Active Lesion? → C/S
→ No Lesion? → V/D
HIV
- Transmission → highest during delivery
- 24% if no prophylaxis
- 8% if w/ prophylaxis
- Mx
- Prenatal → 2 NRTI PLUS 1 NNRTI or protease inhibitor (most important prevention)
- Opportunistic Prophylaxis if CD <200
- No Amniocentesis until viral load undetectable
- Intrapartum
- Mom not on HAART? → Zidovudine
- Viral Load <1000? → Zidovudine PLUS V/D
- Viral Load >1000? → Zidovudine PLUS C/S
[no artificial ROM Or instrumentation]
- Postnatal
- Mother → Continue HAART
- Infant → Zidovudine for >6 wks PLUS serial HIV PCR testing
HTN (mc → IUGR)
- Gestational = >20 wkGA >140/>90 mmHg → give Methyldopa
- Preeclampsia = BP >140/>90 PLUS proteinuria >300 mg/24hr
- Severe? = >1 of:
- Brain → Cerebral, Visual Symptoms
- Lung → Pulmonary Edema
- Heart → BP (>160/110) on 2X 4hr apart
- Liver → ↑ transaminases
- Kidney → Cr >1.1 mg/dL OR doubling
- Blood → PLT <100K
→ PTE? Must deliver
→ w/o severe features?
→ <34 wkGA? → observe (OPD)
→ >34 wkGA? → induce delivery
→ w/ severe features?
→
→ >34 wkGA?
→ MgSO4 (drips intraP)
→ AntiHTN
- Hypetensive Moms Need Love
- Hydralazine
- Methyldopa
- Nifedipine (2nd)
- Labetalol (1st)
→ Delivery (only cure for PTE)
→ Continue MgSO4 for 24hr postpartum
→ hyporeflexia followed by hypotension?
→ STOP MgSO4
- HELLP = Hemolysis + Elevated Liver enzymes + Low PLT
→ PTE + N/V + RUQ pain?
→ HELLP?
→ Stabilize (AntiHTN ‘Labetalol, Hydralazine’ and/or MgSO4 ‘prevents seizure’)
→ Delivery ( at >34 wkGA OR any GA w/ abomral baby test or severe/worsening mom)
[Hypertensive w/ Low PLT? → General Anesthesia]
- Eclampsia = Clinical Dx = preeclampsia w/ grand mal seizure
- Chronic = <20 wkGA OR <pregnancy
CC
- Maternal?
- GDM
- superimposed PTE
- PPH
- Placental Abruption
- C/S
- Fetal?
- IUGR
- Preterm Delivery
- Oligo
Hx C/S Smoking
Risk Hx Fibroid
PPROM
- Mx?
→ Bleed >20wk? (Do speculum ‘Confirm bleed’ followed by TVUS ‘Evaluate Placenta’)
→ Abdominal Pain?
→ Yes (Placental Abruption)
→ Stable Mother and Fetus? → V/D after 36wk
→ Unstable Mother? → C/S unless V/D impending
→ No
→ BEFORE ROM (Previa) → admit then C/S after 37wk
→ AFTER ROM (Vasa w/ctg → emergent C/S
PPH = >500mL V/D/>1000mL C/S/bleed causing shock (1ry w/i 24hr/2ry >24hr + <12wk)
- ET → 4T’s
- 80% Tone (Uterine Atony)
- 20% Trauma (laceration, inversion)
- 10% Tissue (retained placenta)
- Accreta 80% (Attached to myometrium)
- Increta 15% (Invade myometrium)
- Percreta 5% (Perforates myometrium)
Dx?
→ Clinical (PPH upon manual separation of the placenta)
→ Initial U/S
→ Confirm Doppler U/S
→ Best MRI
- 1% Thrombin
- bleeding diathesis
- DIC
- Placental Abruption
- Amniotic Embolism
- Prolonged fetal death
Uterine Atony
- ET → AEIOU
- Anatomic Abnormalities
- Exhausted myometrium
- Prolonged labor
- Oxytocin use
- Halogen Anesthesia
- MgSO4
- >5 multiparity
- Leiomyoma
- Chorioamnionitis
- Infections
- Overdistended Uterus → (twin, poly, macro)
Trauma
- ET
- Iatrogenic injury
- Instrumental delivery
- Cervical laceration: most commonly caused by forceps use
- Lower vaginal trauma: most commonly due to episiotomy
- cesarean delivery → Uterine Rupture
- Mx
- Prevent → Active Mx (no C/S or V/D)
→ Oxytocin (Once Shoulder delivered)
→ Fundus Massage
→ Cord Pulling
→ Controlled Cord Clamping
→ Bimanual Massage & External Compression
- Acute
→ Large IV bore, Face Mask, Monitor Vitals, Send CBC
→ Cause?
- Tone?
→ IV Oxytocin w/ Bimanual Massage
→ Fail?
→ ↑ Oxytocin Dose to 40
→ Add Carboprost OR Methergine OR PG1 OR misoprostol
- Oxytocin → C/I in hypersensitivity
- Carboprost → C/I in asthma, active heart dis. Liver dis. Kidney dis.
- Methergine → C/I in HTN, HIV, Heart Disease
→ Fail?
→ Tranexamic acid (w/i 3hr of PPH)
→ Fail?
→ Surgical
→ C/S?
→ Lacerations?
→ Yes → suture ligation
→ No → B-Lynch (compression suture)
→ V/D? → Start Medical, Message
→ Fail?
→ Hysterectomy (definitive)
(embolization if stable only)
- Tissue?
→ remove placenta manually
→ curettage under anesthsia
→ accreta, increta, percreta?
→ hysterectomy
- Trauma (inversion)
→ Reduce Uterus Manually
→ Anesthesia for pain
→ IV fluid & oxytocin
- Thrombin
- CC
- Anemia
- Brain → Sheehan (Hot and Hyped Actress Have Fixed Post With Income in Dollars)
- Hot Hot Flushes
- Hyped Hypotension
- Actres Agalactia
- Have HypoT
- Fixed Fatigue
- Post PPH
- With Weight Gain
- IncomeInsipidus
- Dollars Decreased Libido
- Transfusion reaCtion
- Mother, Baby Death
- VTE
- inFection
2ry PPH Mx
→ PPH >24hr (delayed)?
→ Stable?
→ No → Exploratory Laparotomy
→ Yes
→ Hx, Ex, Labs
→ Endometritis? (Fever ,tender uterus, Foul lochia, Leukocytosis)
→ Yes → IV clindamycin + IV aminoglycoside such as gentamicin
→ U/S
→ No
→ Pelvic U/S doppler
→ Tissue Retained?
→ Yes → Curettage
→ No → U/S (look for vascular, aneurysm)
- Shoulder Dystocia?
→ McRoberts (flex thighs) OR Apply Suprapubic Pressure
→ Fail?
→ C/S
- Bad Uterine Contractions? → Oxytocin
- ECV (if EVC fail OR <37 wk baby goes down → C/S otherwise wait it will turn spontaneously)
- Do → >37 wk w/ breech presentation wishes V/D
- Don’t
- Antepartum bleed, Active labor
- Baby anomalies, Placental abnormalities (low lying)
- Constriction (oligohydramnios)
- Explosion (ROM), Extended fetus neck
- Fetus non reassuring CTG
- Had C/S before
- Anesthesia?
- Epidural? → Early Stage (<3 cm dilatation) most common+most safe
- Pudendal? → Late Stage (3+ cm dilatation)
(Active Stage? → Epidural)
- Spinal? → non Urgent C/S
- General? → ↓BP OR Risk Bleed (↓PLT) CHOICE for Urgent C/S
(90% effacement, 4cm dilatation ‘active’, baby distress?
→ emergency C/S ‘use general anesthesia’)
OVD
- Do’s
- Long Stage 2 (Failure of baby head rotation, mom heart D. Or exhausted)
- Leg (breech ‘forceps’)
- bad fetaL CTG (brady, decelerations)
- Don'ts
- Unengaged Head
- Bleeding Disorder
- Bullets
- Stage 2 (full dilatation) exhausted? → Vacuum
- CC → Perineal Tear
- 1st Skin + Subcutaneous perineum + vagina epithelium
- 2nd Skin + Perineal Muscle ‘body’
- 3rd External anal sphincter + internal
- 4th ALL (1st, 2nd, 3rd) + rectal mucosa
Cord Prolapse
→ Presentation (Breech), Polyhydramnios, Premature birth
→ Umbilical Cord btw presenting part and Pelvic wall?
→ ROM followed by CTG bradycardia, deceleration
→ Trendelenburg position
→ fetus is pushed back into the uterus
→ immediate tocolysis using β2-mimetics (fenoterol)
→ emergency C/S
Postpartum
- Don’ts
- Hx ruPture uterus
- Placenta previa, vasa Previa
- Position (Transverse)
- cord Prolapse
- Active genital maternal herPes
- Nonreassuring Pump (CTG)
Prevalence +++ ++ +
Anti-dep, psych
Tx reassurance Antidepressant not left alone
Breastfeeding
- Counselling? → before conceiving
- Colostrum? 1st expelled milk (yellow) ↑ protein
- Contraception?
- Progestin Only Pills (Best)
- Sterilization
- Barriers
- IUD
- Combined OCP (pass in milk + ↓ milk)
- Contraindications
- Maternal
- Active Alcohol/Drug abuse, Active untreated TB (breastfeed 2wk after antiTB)
- HIV, HSV breast lesion (HBV, HCV not a contraindication unless niplle crack or bleed)
- Varicella infection 5ds before or 2ds after delivery
- CTX, RTX
- Common Problems
- Engorgement
→ Bilateral Tender Symmetric Fullness w/o erythema and fever
→ Cool Compressor w/ NSAIDS, Acetaminophen (improves w/ regular feeding, pumping)
- Mastitis
→ Staph A
→ Unilateral tender swollen erythema w/ Fever
→ Continue breastfeeding (to prevent abscess), Analgesics, Cold Compressors
→ dicloxacillin or cephalexin
→ no response, fluctuating mass?
→ Abscess
→ stop breastfeeding & I/D
Breech
→ Head palpated at fundus?
- Frank flexed hips and extended knees
- Complete flexed thighs and legs
- Single Foot 1 hip flexed
- Double Foot 2 hips extended
→ TAUS
→ no placenta previa OR active lesion
→ ECV (if not C/I)
→ Fail?
→ C/S at 39 wk
Apgar Score