STS Full Module 12
STS Full Module 12
Learning Outcome:
Analyze and critique specific issues and
concerns on Science and Technology and
its impact to the Society.
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Chapter 3.1 : The Effects of Assisted Human
Reproduction
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In Vitro fertilization
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There are five basic steps to IVF:
The man's sperm is placed together with the best quality eggs. The mixing
of the sperm and egg is called [Link] and sperm are then stored in an
environmentally controlled chamber. The sperm most often enters (fertilizes) an egg
a few hours after [Link] the doctor thinks the chance of fertilization is low,
the sperm may be directly injected into the egg. This is called intracytoplasmic
sperm injection (ICSI).Many fertility programs routinely do ICSI on some of the eggs,
even if things appear normal.
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• Issues and Concerns
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Gamete Donation
Another ethical and legal issue surrounding the use of donated gametes is to
what extent the anonymity of the donor should be preserved. The issue of
anonymity as it relates to gamete and embryo donation is emotionally charged.
Indeed, the ability of human beings to know their genetic roots is universally
important, at the core of self
identity. Either egg and sperm donors may choose to or not to be anonymous,
though the vast majority in both groups generally chooses anonymity . The
American Society for Reproductive Medicine has identified four levels of gamete
donor information sharing depending on the wishes of the donor and recipient
parties. Recently, however, there is, increasing consideration of the rights of
offspring as it relates to donor gametes and anonymity. Advocates for allowing
either gamete donors or their offspring to break anonymity cite the medical
advantages of sharing medical information with their genetic offspring, in the
case of the donor, or learning about their genetic history directly, in the case of
offspring . Others simply argue that both donors and offspring have an inherent
right to meet and develop a relationship. Recent court rulings suggest that these
rights will become more visible in the future. The ethical and legal issues
surrounding anonymity and gamete donation are sure to be a centrally debated
issues within the field of ART for the foreseeable future.
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Activity 1: Short Response
• In not more than 1000 words, cite some examples of assisted human reproduction
and what are their impacts in the society. Discuss the advantages and
disadvantages of using these assisted human reproduction methods.
Criteria to be 4 3 2 1
Assessed
1. Ideas Writing Writing presents Writing presents Writing presents
successfully the topic in an the topic in an topic in an
presents the topic interesting way. ordinary way. ordinary way.
in a novel or Writing includes Writing includes Concrete details
unique way. good concrete concrete detail, but and commentary
Writing includes detail and some commentary is are either weak or
excellent and insightful obvious, simplistic, missing.
specific concrete commentary. or generic.
detail and
insightful
commentary.
2. Organization Writing has a Writing has a Organization is Writing is aimless
compelling and logical flow of rough but and disorganized.
logical ideas. workable. It
flow of ideas. sometimes gets off
topic.
3. Topic Paragraphs have Paragraphs have Paragraphs have Paragraphs lack
Sentences focused and focused topic topic sentences topic sentences
and poignant topic sentences and that need to be and transitions.
Transitions sentences and obvious more focused and
smooth, almost transitions. rough transitions.
seamless
transitions.
4. Description Writing consistently Writing shows Writing includes Writing uses all
and effectively rather than tell, some showing but telling and no
shows rather than but details could needs more. showing.
tells through be more specific
specific and vivid and vivid.
details.
5. Word Choice Writing uses words Writing makes Writing uses words Writing uses the
that are striking some quality but that are dull or same words over
and fresh but also some routine uninspired. and over. Some
natural, varied, and or ordinary word Writing sounds like words may be
vivid. choices. you are trying too confusing or
hard to impress. inappropriate.
6.. Grammar Writing uses proper Writing has a few Writing has enough Writing has
Usage grammar 100% of grammar grammar errors to numerous
and Sentence the time. problems. distract a reader. grammar
Fluency Sentences flow well Sentences flow Some sentences do mistakes and
and vary in well but do not not flow well poor sentence
construction and vary much. and/or are not construction that
length. varied at all. make the paper
hard to read.
7.. Spelling and Writing uses Writing has a few Writing has enough Writing has
Punctuation correct punctuation errors to fix, but errors in the essay numerous errors
and spelling 100% generally uses to distract a reader. that make the
of the time. correct paper hard to
conventions. read.
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Chapter 3.1.2 Mechanisms of action and effectiveness of
contraceptive methods
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Method How it works Effectiveness: Effectiveness:
pregnancies per pregnancies per
100 women per 100 women per
year with year as commonly
consistent and used
correct use
is a surgical
procedure for male
sterilization or
permanent
contraception.
During the
procedure, the
male vasa
Male sterilization deferentia are cut
0.1 0.15
(Vasectomy) and tied or sealed
so as to prevent
sperm from
entering into the
urethra and
thereby prevent
fertilization of a
female through
sexual intercourse.
is a surgical
procedure for
female sterilization
in which the
fallopian tubes are
permanently
Female sterilization
blocked or 0.5 0.5
(tubal ligation)
removed. This
prevents the
fertilization of eggs
by sperm and thus
the implantation of
a fertilized egg.
Prevents the
Lactational
release of eggs
amenorrhea 0.9 (in six months) 2 (in six months)
from the ovaries
method (LAM)
(ovulation)
Prevents
pregnancy by
Standard Days avoiding
5 12
Method or SDM unprotected
vaginal sex during
most fertile days.
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Method How it works Effectiveness: Effectiveness:
pregnancies per pregnancies per
100 women per 100 women per
year with year as commonly
consistent and used
correct use
Prevents or delays < 1 for ulipristal
Emergency
the release of eggs acetate ECPs
contraception pills
from the ovaries. 1 for progestin-
(ulipristal acetate
Pills taken to only ECPs
30 mg or
prevent pregnancy 2 for combined
levonorgestrel 1.5
up to 5 days after estrogen and
mg)
unprotected sex progestin ECPs
The couple
prevents
pregnancy by
avoiding
unprotected Reliable
Calendar method
vaginal sex during effectiveness rates 15
or rhythm method
the 1st and last are not available
estimated fertile
days, by
abstaining or using
a condom.
Tries to keep
sperm out of the
Withdrawal (coitus 4
woman's body, 20
interruptus)
preventing
fertilization
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Activity 2: Crossword Puzzle
1 3
2
4 5
1 2
6 3 7
4
8
9
10
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ASSESSMENT TASK
B. Discussion:
1. Discuss briefly all the Assisted Reproductive Technology methods.
2. 2. Are you in favour in using these ART methods? Why or Why not?
Rubrics
Response 40%
Main/Topic Idea Sentence 40%
Mechanics and Grammar 20%
100%
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References:
Family Planning: A Global Handbook for Providers. 2018 World Health Organization
and Johns Hopkins Bloomberg School of Public
Health. [Link]
[Link]?sequence=1
Kantorová V, Wheldon MC, Ueffing P, Dasgupta ANZ (2020) Estimating
progress towards meeting women’s contraceptive needs in 185
countries: A Bayesian hierarchical modelling study. PLoS Med
17(2):e1003026. [Link]
371/[Link].1003026
United Nations, Department of Economic and Social Affairs, Population Division.
Family Planning and the 2030 Agenda for Sustainable Development. New York:
United
Nations. [Link]
amily/familyPlanning_DataBooklet_2019.pdf
Family Planning Can Reduce High Infant Mortality Levels. Guttmacher
Institute. [Link]
_2-[Link]
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Chapter 3.2 : GM Products: Issues and Concerns and Ensuring
their Safety
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Technological Issues:
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Biosafety and Risk Assessment
• The assessment of genetically modified food crops is based on the concept of substantial
equivalence first formulated by the Organisation for Economic Cooperation and
Development (OECD) in 1993 and discussed and established by several technical expert
panels of the Food and Agricultural Organization (FAO)/ World Health Organization
(WHO) of the United Nations in 2000 and Codex Alimentarius Commission in 2003. This
concept is based on the comparison of the transgenic crop with its conventional
counterpart that is generally accepted as safe because of its history of use as human
food. If there is not much difference, or if the difference is similar to the variation between
or among varieties of the crop, the transgenic crop is considered to be as safe as its
conventional counterpart.
• Since the commercial release of GM crops in 1996, there have been many published
scientific articles on the food safety assessment of GM food crops based on substantial
equivalence. Since 2009, such studies have been summarized and reviewed and have
shown that many transgenic crops are similar in composition with their conventional
counterparts using compositional analyses from simple proximate chemical to complex
transcriptone analysis. However, various studies have also revealed the large variability
in the composition of non-transgenic crops. Thus, while some groups oppose the use of
the concept of substantial equivalence to provide evidence for food safety of GM foods,
others believe that evaluation should be restricted only to potentially harmful
coonstituents which are known to be present in some crops and which could affect their
safety. Recently, an examination of 20-years data on compositional analyses of GM and
nontransgenic counterparts revealed overwhelming evidence that genetic engineering is
“less disruptive of crop composition” than traditional breeding and the authors concluded
that the requirement for compositional analysis may not be warranted.
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Biosafety Regulation in the Philippines
In 1990,the first biosafety system in the developing world was established in the
Philippines by Executive Order no. 430 signed by president Corazon C. Aquino wherein the
National Committee on Biosafety of the Philippines was established to implement the
biosafety system .
In addition, the NCBP’s functions included the review and monitoring of research
and development involving genetically modified organisms (GMOs). NCBP, an
interdepartmental committee, consisted of the Department of Science and Technology
(DOST), Department of Agriculture (DA), Department of Health (DOH), and the Department
of Environment and Natural Resources (DENR). The NCBP under EO 430 was attached to
DOST with the DOST Secretary as NCBP Chair.
From 1990 to 2002, the NCBP’s scope of mandate included research and
development in the laboratory, in the screen housed and in the field.
In April 2002, the Department of Agriculture issued Administrative Order No. 8
“Rules and Regulations for the Importation and Release into the Environment of Plant and
Plant Products Derived from the Use of Modern Biotechnology.” The Bureau of Plant
Industry since then has led other agencies of the Department of Agriculture in processing of
applications for field tests, propagation, or for importation of regulated article, for
monitoring and other related regulatory activities.
The other agencies of DA that are involved in regulating GM or bioengineered
crops are as follows: the Fertilizer and Pesticide Authority (FPA) evaluates and registers
bioengineered crops with pesticidal properties; Bureau of Animal Industry (BAI) evaluates
feed safety and the Bureau of Agriculture and Fisheries Product Standards evaluates food
safety (BAFPS) of Primary and secondary-processed agricultural and fishery products.
In March 2006, EO 514 creating the National Biosafety Framework was approved
and implemented in 2009. The DOST Biosafety Committee is tasked with the regulation and
monitoring of contained experiments in the laboratory and screenhouse. The DA Biosafety
Team based at the Bureau of Plant Industry follows the procedures for field testing and
commercialization started under EO 430. It is involved in the processing of applications for
the entry of GM crops for food, feed and processing.
Lab research
Field work
Concept/ Strategy;
choice of Agronomic or Product Advance
gene(s)sources of horticultural traits Evaluation of food and
gene(s); environmental evaluation; genetic feed safely; safety to
or ecological stability; impact on environment
consideration of gene environment.
or product
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R & D and commercial products involving GM technology are regulated from
laboratory research, to field work and to product advancement in the market.
Assessment is strictly science-based, conducted by the regulatory body and its
Scientific and Technical Review Panels and done on a case- by-case basis. There is
public consultation on any technology that will be field-tested or commercialized.
Activity 3: Think-Pair-Share
Look for a partner and discuss the different issues and concerns about the
GM Products and how can we assure the safety of our GM Products.
Rubrics
Please be guided by this criteria:
Response 40%
Main/Topic Idea Sentence 40%
Mechanics and Grammar 20%
100%
References:
Tecson-Mendoza EM (Ed.) 2014. Understanding Biotechnology. Second
Edition. National Academy of science and Technology-Philippine Science Heritage
(NAST-PSH) Foundation Inc., Manila, Philippines.
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ASSESSMENT TASK
I. Multiple Choice
Instruction: Encircle the letter of the BEST answer.
1. The first Philippine biosafety system established under Executive Order no. 430
in 1990 created a government interdepartmental committee in charge of regulating
R&D involving GMOs called:
A. DA-BPI B. National Committee on Biosafety of the Philippines
C. DOH- BFAD D. DA
2. All of these are ways in assuring the safety of GM products EXCEPT for?
A. Lab Research B. Framework
C. Field Work D. Product Advance
3. This committee was created to implement the biosafety system and to identify and
evaluate potential hazards in genetic engineering experiments or the introduction of
GMOs.
A. OECD B. DA
C. NCBP D. NAST PHL
4. Field testing and commercialization of GM crops in the Philippines are regulated
by:
A. DOST B. DTI
C. DA D. WHO
5. The NCBP Biosafety Committee is composed of :
A. DOST, DA, DENR, DOH
B. BPI, DOST, WHO, FAO
C. DENR, DOST, DOH, BPI
D. DOST, DA, DENR, BPI
II. Discussion:
1. Discuss how can one study the food safety and safety to the environment of crops
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