4th stage Pharmacology Quiz no.

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Choose the most appropriate answer:
1-All of the following hormones secrete from anterior pituitary, except:
A-Growth hormone B-Prolactin C-Human chorionic gonadotropin D-Luteinizing hormone
E-Thyrotropin stimulating hormone
2-One of the following used diagnostically to differentiate between Cushing syndrome and ectopic
ACTH- producing cells is:
A-Somatostatin B-Somatotropin C-Adrenocorticotropic
hormone D-Corticotropin releasing hormone E-Cortisol
3-Which of the following consider preferred for the diagnosis of adrenal insufficiency:
A-Somatotropin B- Cortisol C- ACTH D-Cosyntropin E-None of above
4-long term use of ACTH may cause all the following toxicities, except:
A-Emotional disturbance B-Hyperkalemia C-hypertension D-Edema E-Infection
5- The posterior pituitary does NOT secret:
A-Vasopressin B- Oxytocin C- Growth hormone D-A&B E-All of the above
6- Correct statements about adrenocorticotropic hormone (ACTH) include all of the following, EXCEPT:
A-Endogenous ACTH is also called corticotropin B- ACTH stimulates the synthesis of
corticosteroids
C- With longer use, toxicity may cause emotional disturbances
D-The oral route is the preferred rout of administration E-None of above
7- Which one of the following compounds is not a hormone?
A-Cabergoline B-Somatomedin C-Somatotropin D-Thyroxine E-Vasopressin
8-Which one of the following hormones not synthesized in the hypothalamus?
A-Corticotropin–releasing hormone B-Luteinizing hormone C-Oxytocin D-Thyrotropin–releasing
hormone E-Vasopressin
9-All of the following substances are endogenous topic hormones secreted by the pituitary gland except:
A-Somatotropin B-Human chorionic gonadotropin (HCG) C-Follicle-stimulating hormone (FSH)
D-Thyroid-stimulating hormone (TSH) E- Adrenocorticotropic hormone (ACTH)
10-Somatotropin released in response to:
A-Somatropin B-Somatostatin C-Growth hormone inhibiting hormone
D- Growth hormone stimulating hormone E-B&C

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11-Gigantism occur in response to:
A-Overproduction of GH after puberty B- Overproduction of somatostatin
C- Overproduction of GH before puberty D- Overproduction of GH during 18-20 years old
E-None of above
12-Reduction of somatotropin release may cause:
A-Acromegaly B-Gigantism C- Addison disease D-Dwarfism E-Cushing
syndrome
13-One of the following is not function of Growth hormone:
A-Weight gain B-Glycogenolysis C-Lipolysis D-Protein synthesis E-Bone density
elevated
14- A 43 years old patient diagnosed with HIV for one year ago, and after 6 months start with
unexplained weight loss and Cachexia, which of the following is suitable for such case:
A-Somatostatin B-Somatotropin C-Somatropin D-Octreotide E-None of above
15-One of the following is synthetic GH:
A- Somatotropin B-Somatostatin C-Lanreotide D-Somatrem E-None of above
16-All of the following are contraindicated of synthetic GH, except:
A-Prader-willi syndrome B-Pediatric with closed epiphyses C-Diabetic retinopathy D-
Acromegaly E-Dwarf patient
17- Which one of the following isn’t adverse effect of synthetic growth hormone?
A-Arthralgia B-Risk of generalized infection C-Myalgia D-Diabetes risk E-Edema
18-Somatostatin inhibit all the following, except:
A-Insulin B-Glucagon C-Gastrin D-GH E- Cortisol
19-A 22 years old male admitted to hospital with severe diarrhea, flushing episodes associated with
carcinoid tumor, which of the following consider more suitable treatment for such case:
A-Somatrem B-Somatropin C-Cosyntropin D-Octreotide E-Somatotropin
20- Galactorrhea and hypogonadism can treated with which of the following:
A-Antipsychotic drugs B-Cabergoline C-Metoclopramide D-Octreotide E-None of above
21- Indications of bromocriptine are following, EXCEPT:
A-Prolactin-secreting adenomas B-Amenorrhea-Galactorrhea C-Prolactin deficiency
D-Acromegaly E-All of above
22-Menotropins is a preparation of:
A-FSH + LH obtained from urine of menstruating women

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B-LH obtained from urine of pregnant women C-FSH + LH obtained from urine of menopausal
women
D-LH obtained from serum of pregnant mares E-None of above
23- A 40-year-old female is undergoing infertility treatments. Which drug might be included in her
treatment regimen?
A. Cabergoline B. Follitropin C. Methimazole D. Vasopressin E-None of above
24-A 34 years old woman with secondary infertility for 6 years ago, which of the following procedures
convenient for conception:
A-Menotropin for 5 day, then follitropin beta for 12 days B-Urofollitropin then
HCG C-Menotropin at first then HCG D-HCG for 12 days the Menotropin for 10 days
E- A&D
25- One of the following may help for breast feeding induction:
A-Metoclopramide B-Bromocriptine C-Cabergoline D-Levothyroxine E-Octreotide
26- One of the following consider the life threatening adverse effect during oxytocin uses:
A-Hypertension B-Hypokalemia C-Water retension D-Repture uterus E-all of above
27- A 27-year-old woman with amenorrhea, infertility, and galactorrhea was treated with a drug that
successfully restored ovulation and menstruation. Before being given the drug, the woman was
carefully questioned about previous mental health problems, which she did not have. She was
advised to take the drug orally. Which of the following is most likely to be the drug that was used to
treat this patient?
A-Bromocriptine B-Desmopressin C-Human gonadotropin hormone D-Leuprolide E-Octreotide
28- A 3-year-old girl was referred to the genetic counselor by her pediatrician. She presents with
short stature (height is 85 cm) and appears to have loose skin on her neck. Which of the following
drugs will allow her to achieve a higher adult height?
A-Adrenocorticotropin (ACTH) B-Corticotropin-releasing hormone (CRH)
C-Growth hormone-releasing hormone (GHRH) D-Gonadotropin-releasing hormone (GnRH)
E-Somatropin
29- A 47-year-old man exhibited signs and symptoms of acromegaly. Radiologic studies indicated
the presence of a large pituitary tumour. Surgical treatment of the tumour was only partially effective
in controlling his disease. At this point, which of the following drugs is most likely to be used as
pharmacologic therapy?
A-Cosyntropin B-Desmopressin C-Bromocriptine D-Octreotide E-Somatropin
30- A 37-year-old woman with infertility due to obstructed fallopian tubes was undergoing ovulation
induction in preparation for in vitro fertilization. Which of the following involve treatment such case?
A-Bromocriptine B-Follitropin C-Gonadotropin D-hCG E-Pergolide
31- A young couple (25-year-old male, 23-year-old female) wants to start a family. They have not
conceived after 1 year of unprotected intercourse. Infertility evaluation revealed no abnormalities in

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the female partner and low sperm count in the male. Which of the following is a drug that is purified
from the urine of postmenopausal women and is used to promote spermatogenesis in infertile men?
A- Choriogonadotropin alfa B- follitropin beta C-HCG D-Somatropin E-Urofollitropin

32- A child with severe asthma is treated with high-dose inhaled corticosteroids. Which adverse
effect is of particular concern?
A. Hypoglycemia B. Hirsutism C. Growth suppression D. Cushing syndrome E-All of above
33- Indications of vasopressin are following:
A-Diabetes mellitus B-Hypertension C-Pituitary diabetes insipidus D-Incompleted abortion
34- Vasopressin possesses the following:
A-Antidiuretic property B-Vasodilatation property C-Release of a thyroid hormone into the plasma
D-Diuretic property E-All of above
35- Vasopressin analogue preferred for the treatment of diabetes insipidus and nocturnal enuresis is:
A-Cosyntropin B-Desmopressin C-Bromocriptine D-Octreotide E-Oxytocin
36-Which of the following diabetes medications is most appropriately paired with an adverse effect
associated with its use:
A-Canagliflozin—urinary tract infections [Link]—heart failure [Link]—weight loss
D. Liraglutide—lactic acidosis
37-Kali Doil is a 69-year-old male with type 2 diabetes and chronic pancreatitis. Which of the
following diabetes medications is contraindicated in this patient?
A. Glipizide B. Insulin lispro C. Metformin D. Dulaglutide E-All of above
38-Which is the most appropriate initial oral agent for management of type 2 diabetes in patients
with no other comorbid conditions?
A. Glipizide B. Empagliflozin C. Metformin D. Pioglitazone E- A&C
39-HB is a 55-year-old obese female who has had type 2 diabetes for 10 years. She is currently
being treated with metformin, but her HbA1c is above goal. She has a history of heart failure and
chronic obstructive pulmonary disorder. Her physician would like to add a medication that will not
cause any weight gain. Which of the following would be most appropriate to control HB’s diabetes?
A. Linagliptin B. Glimepiride C. Pioglitazone D. Inhaled insulin
40-Which class of oral diabetes drugs is paired most appropriately with its primary mechanism of
action?
A. DPP-4 inhibitor—inhibits breakdown of complex carbohydrates
B. SGLT2 inhibitor—increases urinary excretion of glucose C. Sulfonylurea—increases insulin
sensitivity D. Thiazolidinedione—decreases hepatic gluconeogenesis
41-A 27-year-old man was recently diagnosed with Type-2 diabetes mellitus and placed on a

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medication. As he was drinking with his friends, he became severe hypoglycaemic and hypotention.
What medication is he most likely taking?
(A) Acarbose (B) Glipizide (C) Metformin (D) Pioglitazone
42-A 62-year-old female with diabetes presents to her primary care physician for follow-up. She
takes pioglitazone daily and her blood sugar ranges approximately from 100 to 180 mg/dL. Which of
the following indicators would likely have minimal or no change from baseline values with this
therapy?
(A) Glucose (B) Hemoglobin A1c (C) Insulin (D) Low-density lipoprotein
43-A 54-year-old man with Type-2 diabetes presents to the ambulatory care clinic for follow-up. He
was diagnosed with diabetes 6 months ago and was started on oral medication then. His blood
sugar has been under good control with a hemoglobin A1c of 6.7%. He has not had any
hypoglycemic episodes. His only complaint is that despite daily exercise and eating healthier, he has
gained 12 lb in the last 6 months. What medication is most likely to cause his weight gain?
(A) Acarbose (B) Exenatide (C) Glyburide (D) Metformin (E) Pioglitazone
44-Potassium level affect in the mechanism of action in all the following, except:
A-Nateglinide B-Glimepiride C-Rosiglitazone D-Repaglinide
45-Which of the following had drugs had increase of hypoglycaemic incidence of metformine:
A-Miglitol B-bromocriptine C-Linagliptin D-Glimepiride
46-which of the following states had stimulate the growth hormone releasing:
A-Glucagon B-Hyperglycaemia C-Free fatty acids D-Cortisol
47-Patient with severe diarrhoea/flushing episodes associated with carcinoid tumours, which of the
hormonal treatment is/are suitable:
A-Somatropin B-Octreotide C-Menotropin D-Cabergoline E-None of above
48-Regarding duration of action, which of the following oral anti diabetic drugs involve longest acting:
A-Meftformin B-Glipizide C-Pioglitazone D-Canagliflozin
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49-One of the following drugs involve ATP-dependent K channel blocking:
A-Rosiglitazone B-Nateglinide C-Metformin D-Acarbose
50-Which of the following oral anti diabetic drugs involve stimulation of insulin release
A- Pioglitazone B- Metformin C-Insulin lisipro D-Glimepride
51-Hyperinsolinemia, hypoglycaemia, and weight gain are adverse effects of one of the following:
A-Dapagliflozin B-Glyburide C-Metformin D-Rosiglitazone
52-One of the following drugs used for treatment polycystic ovarian syndrome:
A- Metformin B-Miglitol C-Linagliptin D-Empagliflozin
53-Which of the following anti diabetic drugs not involve hypoglycaemia:

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A-Glimepiride B-Repaglinide C-Alogliptin D-Glyburide
54-Metformin is contraindicated in all the following, except:
A-Patient with heart failure B-Carbohydrate highly intake patient C-Renal
dysfunction D-Patients older than 80 years E-All of above
55-Which of the following oral anti diabetic drugs involve peroxisome proliferator-activated receptor
gamma agonist:
A-Sexagliptin B-Acarbose C-Rosiglitazon D-Erugliflozin
56-All of the following oral anti diabetic drugs are contraindicated in heart failure, except:
A-Linagliptin B-Saxegliptin C-Pioglitazon D-Metformin
57-Which of the following oral anti diabetic drugs is α-glucosidase inhibitor:
A- Metformin B- Alogliptin C-Acarbose D-Empagliflozin
58-Which of the following oral anti diabetic drugs involve nasopharyngitis adverse effect:
A-Acarbose B-Biguanides C-Canagliflozin D-Saxagliptin
59-Which of the following oral anti diabetic drugs involve inhibition of sodium glucose cotransporter
II:
A-Metformin B-Glipizide C-Empagliflozin D-Linagliptin
60-One of the following oral anti diabetic drugs involve valvovaginal candidiasis adverse effect:
A-Miglitol B-Repaglinide C- Metformin D-Dapagliflozin

Lecturer [Link] Faris Behia

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