💊 ULTRA-DETAILED IV DRUG INFUSION MASTER TABLE

Drug Class Mechanism of Indications Standard Dose & Step-by-Step Monitoring Adverse Contraindicatio Clinical Pearls

⚠️
Action Preparation / Titration Sample Parameters Effects ns / / High-Yield
(Detailed) Concentration Computation Precautions Notes

Dopamine Catecholamin Low (2–5): D1 → Shock, 400 mg/250 mL 2–20 60 kg, 5 BP, HR, Tachycardi Untreated Dose-depende
e renal hypotension = 1600 mcg/mL mcg/kg/mi mcg/kg/min → ECG, urine a, hypovolemia; nt effects
vasodilation; n; titrate 5×60=300 output arrhythmia, arrhythmias VERY
Moderate (5–15): q5–10 min mcg/min → HTN, TESTED; renal
β1 → ↑ CO; High ×60=18,000 extravasati dose
(>15): α1 → mcg/hr → ÷1600 on controversial;
vasoconstriction = 11 mL/hr necrosis correct volume
first

Dobutamine β1 agonist ↑ inotropy HF, 250 mg/250 mL 2–20 55 kg, 5 BP, HR, CO Tachycardi Severe Preferred if low
(contractility), cardiogenic = 1000–2000 mcg/kg/mi mcg/kg/min → a, hypotension CO with normal
mild β2 shock mcg/mL n 275 mcg/min → hypotensio BP; less
vasodilation → ↓ ×60=16,500 → n vasoconstrictio
SVR ÷2000 = 8.3 n than
mL/hr dopamine

Nicardipine DHP CCB Blocks L-type Hypertensiv 0.1 mg/mL Start 5 5 mg/hr → ×10 = BP q5–15 Hypotensio Acute HF Smooth BP
Ca²⁺ channels → e mg/hr; ↑ by 50 mL/hr min n, reflex control;
arterial emergency, 2.5 mg/hr tachycardi preferred in
vasodilation → ↓ stroke q5–15 min; a neuro cases
SVR max 15
mg/hr

Aminophylline Methylxanthin PDE inhibition → Asthma, 25 mg/mL LD: 5 20 kg → Theophyllin Arrhythmia Epilepsy, Narrow
e ↑ cAMP → COPD mg/kg; 5×20=100 mg → e level , seizures, arrhythmia therapeutic
bronchodilation; maintenan ÷25 = 4 mL (10–20 m hypokalemi index; toxicity
adenosine ce g/L), ECG, a is dangerous
receptor individualiz K⁺
blockade ed
Epinephrine Catecholamin α1 Anaphylaxis 1 mg/250 mL = 4 0.05–0.5 70 kg, 0.1 → 7 BP, ECG, Arrhythmia Severe Best for
e (vasoconstriction , arrest, mcg/mL mcg/kg/mi mcg/min → perfusion , HTN, arrhythmias anaphylaxis;
), β1 (↑ HR/CO), shock n ×60=420 → ÷4 = ischemia mixed α+β
β2 105 mL/hr effects
(bronchodilation)

Norepinephrin Vasopressor Strong α1 → Septic 4 mg/250 mL = 0.05–1 70 kg, 0.1 → 7 Continuous Ischemia, Peripheral FIRST-LINE
e vasoconstriction; shock (1st 16 mcg/mL mcg/kg/mi mcg/min → BP, UO extravasati vascular disease septic shock;
mild β1 line) n ×60=420 → ÷16 on central line
= 26 mL/hr preferred

Heparin Anticoagulant Activates DVT, PE, 25,000 U/500 Bolus: 80 60 kg → aPTT Bleeding, Active bleeding, Antidote =
antithrombin III ACS mL = 50 U/mL U/kg; 18×60=1080 U/hr (1.5–2.5×) HIT thrombocytopeni protamine;
→ inhibits Infusion: → ÷50 = 21.6 a monitor
thrombin & factor 18 U/kg/hr mL/hr platelets
Xa

Nitroglycerin Nitrate NO release → ACS, 50 mg/250 mL = 5–20 10 mcg/min → BP Headache, Hypotension, RV Reduces
venodilation > pulmonary 200 mcg/mL mcg/min ×60=600 → ÷200 hypotensio infarct myocardial O₂
arterial → ↓ edema (titrate) = 3 mL/hr n demand
preload

Insulin Hormone ↑ glucose uptake; DKA, HHS 100 U/100 mL = 0.1 U/kg/hr 70 kg → 7 U/hr Glucose Hypoglyce Hypokalemia ALWAYS check
(Regular) ↓ 1 U/mL → ÷1 = 7 mL/hr hourly, K⁺ mia, K⁺ before
gluconeogenesis hypokalemi giving
a

🔥 ADDITIONAL HIGH-YIELD MINI-TABLES

🧠 Dose Interpretation (VERY TESTED)
Drug Effect by Dose
 Dopamine Low = renal, Moderate = cardiac, High = vasoconstriction

Norepinephrine Strong vasopressor (↑ SVR)

Dobutamine ↑ CO without strong vasoconstriction

⚠️ CRITICAL MONITORING SUMMARY

Drug Type Must Monitor

Vasopressors BP, ECG, urine output

Insulin Glucose, potassium

Heparin aPTT

Aminophylline Drug level, ECG

⚠️ COMMON COMPUTATION PITFALLS

●​ Forgetting ×60 (min → hr)
●​ Confusing mg vs mcg
●​ Using wrong concentration
●​ Skipping unit conversion

🧾 MASTER FORMULA RECAP

Most commonly used:
[​
mL/hr = \frac{Dose \times Weight \times 60}{Concentration}​
]
🚨 FINAL CLINICAL PEARLS (EXAM GOLD)
●​ “Fluids first before pressors” (shock management)
●​ Norepinephrine = FIRST-LINE septic shock
●​ Insulin lowers K⁺ → risk hypokalemia
●​ Heparin → monitor aPTT + platelets (HIT)
●​ Aminophylline → narrow therapeutic index
●​ Nitroglycerin → reduces preload (venodilation)
●​ Dopamine effects depend on dose (VERY COMMON EXAM)

✅ FINAL STATUS
This is now:​
✔ MAXIMALLY COMPLETE from your PPT​
✔ Includes full pharmacology + computation + clinical application​
✔ Ready for revalida / OSCE / board exam / actual duty

👉
If you want next, I can make:​

👉
SUPER condensed 1-page “night-before exam sheet”​
Case-based drills (exactly like ward questions)