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Endoplasmic Reticulum

The document outlines the processing of newly synthesized proteins in the endoplasmic reticulum (ER), detailing the roles of signal peptidase, oligosaccharyl transferases, molecular chaperones, and protein disulfide isomerases. It describes the transition of proteins from the ER to the Golgi via vesicles that bud off at ER exit sites, including the ER-Golgi intermediate compartment (ERGIC). A link to a related video is also provided.

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6 views9 pages

Endoplasmic Reticulum

The document outlines the processing of newly synthesized proteins in the endoplasmic reticulum (ER), detailing the roles of signal peptidase, oligosaccharyl transferases, molecular chaperones, and protein disulfide isomerases. It describes the transition of proteins from the ER to the Golgi via vesicles that bud off at ER exit sites, including the ER-Golgi intermediate compartment (ERGIC). A link to a related video is also provided.

Uploaded by

niharikakulkarni8
Copyright
© All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

Endoplasmic Reticulum

Processing of newly synthesized proteins in


ER
• Signal peptide(N terminal ) is chopped off- signal peptidase
• Carbs added- oligosaccharyl transferases
• Molecular chaperons-help in folding, bind to the unfolded, misfolded
– 3D structure
• PDI- protein disulphide isomerases
• From ER-----Golgi
• Vesicles bud off( ER exit sites)-
• ERGIC- ER,G intermediate compartment
• [Link] (SER)

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