Hawassa University
College of Medicine and Health Sciences School of Medicine
2017/2024 Academic Year, Semester I
Module Name (Code): Cardiovascular and Lymphatic System (CVLS 2062)
Module Outline/Plan
Module Coordinator: Mr. Adugnaw A, Lecturer, Physiology Unit Office, Mobile Number 0921287748
ECTS: 12 (8 Weeks) Target Group: Preclinical Year I (2015 Entry Students)
Module Duration: Oct 21 – Dec 13/2024
Module Description:
This system-based module is intended to equip medical students with profound knowledge of basic sciences and development of early clinical
skills relevant to understanding of the cardiovascular and lymphatic system and related clinical problems. Students will also develop relevant
competencies with the Medical expertise, Scholar, Collaborator, Communicator, Manager, Health Advocate and Professional. This module is
given on the second semester during the second year of the pre-clerkship period of the undergraduate medical education program.
Module Objective
By the end of this module, students will be able to apply knowledge of basic sciences for understanding the cardiovascular and lymphatic system
and analyzing disorder of the cardiovascular and lymphatic system.
Supporting objectives
Apply knowledge of the normal structures and functions of the cardiovascular and lymphatic system in analyzing clinical problems
Apply principles of physiologicmechanisms and processes of the cardiovascular and lymphatic system in analyzing clinical problems
Apply principles of human life cycle, growth, development and aging of the cardiovascular and lymphatic system in analyzing clinical
problems including developmental anomalies
Identify the various causes of a disease (genetic, developmental,metabolic, toxic, infectious, autoimmune, neoplastic, degenerative and
traumatic) of the cardiovascular and lymphatic system and analyze the pathogenesis in clinical problems
Analyze the pharmacokinetics and pharmacodynamics of drugs used in the treatment of disorders of the cardiovascular and lymphatic
system
Apply important determinants and risk factors affecting cardiovascular and lymphatic diseases to protect and promote individual and
population health
Demonstrate taking history from the patient with cardiovascular and lymphatic system disorder in a simulated setting.
Demonstrate physical examination pertinent to with cardiovascular and lymphatic system disorder in a simulated setting.
Perform basic investigations in the diagnosis of cardiovascular and lymphatic system disorders
Demonstrate making an initial assessment of a clinical problem related to cardiovascular and lymphatic system in a simulated setting.
Discuss important life style, genetic, demographic, environment, health system, social, economic, psychological and cultural
determinants of cardiovascular and lymphatic system disorders.
Contribute to a culture that promotes patient safety
MODULE CONTENT/SCHEDULE:
Week Day Topic Major teaching learning activities Assigned Instructors
and Assessment
October Anatomy
21/2024 Introduction to the module (1hr) 4 hours of interactive lecture Dr. Dereje.G
Introduction to CVS and overview of thoracic cavity Mr. Tesfaye B
(1hr)
Week I Mediastinum
o Middle mediastinum
Pericardium
Anatomy 4 hours of interactive lecture Dr. Dereje.G
Gross and microscopic structures of the heart Mr. Tesfaye B
Two (0920442342)
Anatomy Practical 3 hours of lab session in the Dr. Dereje.G
Anatomical charts and models afternoon Mr. Tesfaye B
Dissection of Pericardium and heart (0920442342)
Tissue slides and specimens of heart
Anatomy 4 hours of interactive lecture Dr. Dereje.G
Superior mediastinum, Anterior, and posterior mediastinum Mr. Tesfaye B
Three (0920442342)
Anatomy Practical 3 hours of lab session in the Dr. Dereje.G
Anatomical charts and models afternoon Mr. Tesfaye B
Dissection of Pericardium and heart (0920442342)
Tissue slides and specimens of heart
Four SPH II 2 hours of interactive lecture School of PEH
Measurement of health and disease
Anatomy 2 hours of interactive lecture Mr. Chekol B
Development of the heart (0920763293)
Five Anatomy 4 hours of interactive lecture Mr. Chekol B
Development of blood vessels (0920763293)
Physiology 4 hours of interactive lecture Dr. Dubero. S
One Physiology of cardiac muscles
PBL 2 hours of PBL session in the Assigned Instructors
Case of leg edema afternoon
Two Physiology 4 hours of interactive lecture Dr. Dubero. S
Week II Electrophysiology of the heart
Biochemistry 2 hours of interactive lecture Dr. Freshet A
Cardiac energetic (0912868592)
Biomarkers of cardiac injury
Biochemistry Practical 3 hours of lab session in the Dr. Freshet A
Determination of cardiac biomarkers afternoon (0912868592)
AST, CK, LDH, Troponin and Mb
Three Physiology 4 hours of interactive lecture Dr. Dubero. S
The normal electrocardiogram (ECG)
The Cardiac cycle
Physiology Practical 3 hours of lab session in the Dr. Dubero. S
ECG measurement and interpretation afternoon
Four SPH II 2 hours of interactive lecture School of PEH
Measurement of health and disease
Pharmacology 2 hours of interactive lecture Dr. Fikr T
Pharmacology of anti-arrhythmic drugs
Five Pathology 4 hours of interactive lecture Dr. Abebe M
Pathology of the heart
o Heart failure
Pathology 4 hours of interactive lecture
One Pathology of the heart contd. Dr. Abebe M
valvular heart diseases,
congenital heart disease
PBL 2nd PLB session for case of leg Assigned tutors
edema will be continued in the
afternoon
Week Two Pathology
III Pathology of the heart contd. 4 hours of interactive lecture Dr. Abebe M
cardiomyopathies, cardiac tumors, pericarditis and
endocarditis
Pathology practical 3 hours of lab session in the
Audio recordings or computer simulations of the afternoon Dr. Abebe M
dynamics of heart valves and sounds in valvular and
congenital heart diseases
Microbiology
Three Microbes affecting the heart and the pericardium (Valvular 4 hours of interactive lecture Ms. Fitsum A
heart disease, infective endocarditis) (0916061189)
Microbiology Practical 3 hours of lab session in the Ms. Fitsum A
Detection of anti-streptolysin O and S afternoon (0916061189)
Pharmacology Dr. Fikr T
Overview of Pharmacology of autonomic drugs 4 hours of interactive lecture
Pharmacology of drugs used for treatment of infective
endocarditis and pericarditis
Five Test I
One Pharmacology
Pharmacology of sympathomimetics drugs 4 hours of interactive lecture Dr. Fikr T
Week IV Pharmacology of adrenergic blockers (2hrs)
PBL 2 hours of PBL session in the Assigned tutors
A case of chest pain afternoon
Two Pharmacology Dr. Serawit D
Pharmacology of drugs used for treatment of heart failure (0912799841)
Three Anatomy 4 hours of interactive lecture Mr. Chekol B
Major blood vessels of the body(1hr) (0920763293)
Four SPH II 2 hours of interactive lecture School of PEH
Measurement of health and disease
Anatomy 2 hours of interactive lecture Mr. Chekol B
Histology of blood vessels (0920763293)
Anatomy Practical 3 hours of lab session in the afternoon Mr. Chekol B
Anatomical charts and models (0920763293)
• Dissection of blood vessels
• Tissue slides and specimens
• Computer simulations of blood circulation
Five Physiology Practical 3 hours of lab session in the morning TBA
• Measuring blood pressure in different positions and after
exercise
• Measuring arterial pulse after exercise, temporary arterial
occlusion and applying temperature
One Physiology 3 hours of interactive lecture Ms. Leyila T
• Regulation Of Cardiac Output
• The Arterial and the Venous system
PBL Previous PLB session will be Assigned tutors
Week V continued (2hrs)
Two Physiology 4 hours of interactive lecture Ms. Leyila T
The local, humoral and nervous regulation of the
circulation
Regulation of Arterial blood Pressure
Three Physiology 4 hours of interactive lecture Ms. Leyila T
Physiology of microcirculation
Dynamics of the peripheral circulation
Four Pathology 2 hours of interactive lecture Dr. Abebe M
Hypertensive Heart disease
Physiology and Pathology Practical 3 hours of lab session in the afternoon Dr. Abebe M
Computer simulations of blood pressure control
Computer simulations of pathogenesis of hypertensive vascular
disease
Five SPH II 4 hours of interactive lecture School of PEH
Measurement of health and disease
One Pathology 4 hours of interactive lecture
Ischemic Heart Disease Dr. Abebaw A
Peripheral arterial disease
PBL 2 hours of PBL session in the Assigned tutors
A case of severe blood loss afternoon
Two Pharmacology 4 hours of interactive lecture
Week Pharmacology of drugs used for treatment of hypertension Dr. Fikr T
VI and hypotension
Pathology Practical 3 hours of lab session in the afternoon Dr. Abebaw A
Pathology tissue slides and specimen
Three Biochemistry 2 hours of interactive lecture Dr. Freshet A
• Dyslipidaemia (0912868592)
o Familial hypercholesterolemia
o Severe hypertriglyceridemia
o Mechanism of atherosclerosis (LDL/HDL)
o Computer simulations of atherosclerosis
Pharmacology 2 hours of interactive lecture Dr. Serawit D
Pharmacology of agents used in hyperlipidemia (0912799841)
Four SPH II 2 hours of interactive lecture School of PEH
Measurement of health and disease
Pathology 2 hours of interactive lecture Dr. Abebaw A
Pathology of venous disorders (varicose vein,
thrombophlebitis)
Pathology Practical 3 hours of lab session in the afternoon Dr. Abebaw A
Pathology slides and specimens
Five Test II
One Anatomy 4 hours of interactive lecture Mr. Tesfaye B
Anatomy and histology of lymphatic system (0920442342)
• Lymphatic vessels and lymph flow
• Lymphoid tissue
Week PBL Previous PLB session will be Assigned tutors
VII continued (2 hrs)
Two Anatomy 4 hours of interactive lecture Mr. Tesfaye B
Lymphoid organs(thymus, bone marrow, lymph nodes, spleen, (0920442342)
tonsils, MALT)(2hrs)
Development of lymphatic system(2hrs)
Anatomy practical 3 hours of lab session in the afternoon Mr. Tesfaye B
• Anatomical charts and models (0920442342)
• Discussion of lymphoid organs
• Histological slide of lymphoid organs
Three Physiology 2 hours of interactive lecture Ms. Leyila T
Physiology of lymphatic system
Pathology 2 hours of interactive lecture Dr. Abebaw A
Pathology of lymphatic system
Four SPH II 4 hours of interactive lecture School of PEH
Measurement of health and disease
Five Independent study
Week One Independent study
VIII Two Independent study
Three Final Written Exam
Four Independent study
Five OSCE Exam
References
1. Tortora G.J and B. Derrickson. Principles of Anatomy and physiology. 12th edition.2008
2. Drake RL.,Vogl W., and Mitchell [Link]’s anatomy for students. 2007
3. Keith L. Moor, Arthur F. Dally, Anne M.R. Agur. Clinically oriented anatomy. 6th edition. 2010
4. Snell, Richard S. Clinical anatomy by regions / Richard S. Snell. 9th edition. 2012
5. Keith L. Moore, T.V.N. Persaud and Mark G Turchia. The developing human. Clinically oriented embryology (9th edition). 2013.
6. Junqueira’s basic histology: text and atlas. 13th edition. 2013
7. Guyton and Hall. Textbook of medical physiology. 13th edition. 2013.
8. Vanders. Human physiology.13th edition. 2014
9. Ashis Banerjee. Clinical physiology. An examination primer. 2005.
10. Lehninger A.L., principles of biochemistry, 5th edition 2013
11. Voet. D and voet .J . G. Biochemistry , 5th edition, 2012
12. Vasudevan DM, Text book of biochemistry for medical students, Jaypee, 6th edition 2011
13. Eric Arthur Newsholme and Tony R. Leech. Functional biochemistry in health and disease. 2010.
14. John Baynes and MarekDominiczak. Medical biochemistry. 4th edition. 2014
15. Alan Gaw. Clinical biochemistry. An illustrated color text. 5th edition. 2013
16. Richard N Mitchell, Ramzi S. Cotran. Robbins basic pathology. 8th edition. 2007.
17. David A Levison, Robin Reid, Alistair D Burt, David J Harrison and Stewart Fleming. Muir's Textbook of Pathology, Fourteenth
Edition
18. Jawetz, Melnick, &Adelberg's. Medical Microbiology, 24th Ed, 2007
19. Kayser. Medical Microbiology, basic principles (2005)
20. Levinson W. Review of Medical Microbiology and immunology.12th edition.2010
21. Murray P., Rosenthal S., Foller M, Medical Microbiology, 8th edition, 2010
22. Kuby, Goldsby. Immunology. 5thed, 2007.
23. Abhay R. Satoskar [et al.] Medical parasitology. 2009
24. Bertram G. Katzung. Basic and clinical pharmacology. 12th edition. 2011
25. Goodman and Gilman’s. The pharmacological basis of therapeutics. 12th edition. 2011
26. Lynn S. Bickley, Peter G. Szilagyi. Bates’ guide to physical examination and history taking. 10th ed. 2009
Methods of assessment
Progressive
Written progress /quiz/-25%
Biomedical-lab- 10%
PBL-10%
End module
Written -35%
OCSE/OSPE- 20%