SPH 414/514
Risk Assessment and
Characterization
Video 1
What is risk?
Rausand and Haugen
What is risk?
• Risk analysis à risk assessment, risk characterization, risk communication, risk management and policy
1. What can go wrong?
2. What is the likelihood of that happening?
3. What are the consequences?
What is risk?
• Risk analysis à risk assessment, risk characterization, risk communication, risk management and policy
• Risk assessment: scientific evaluation of the probability of harm resulting from exposure to a toxic
(infectious) substance
• Risk characterization: the nature and magnitude of health risk considering the exposure assessment
and hazard identification à includes consideration of the uncertainty associated with each
• Risk communication: the science of communicating risk effectively, particularly in situations that are of
high concern, sensitive or controversial.
• Risk management: the decision-making process related to risk. Includes consideration of the political,
social, economic and scientific/engineering dimensions related to a hazard with an end goal being to
develop an optimal response to the hazard.
The risk triad
Risk management
Regulatory decisions
Determine tolerance
Enforce regulations
a te
Ri
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sk
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Hazard m
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identification i ve
ac
at Public and
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political opinions
Le
at
io
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Dose response
relationships Consideration of
risks and benefits
Exposure
Benefits
assessment Psychological and
assessment
sociologic factors
Risk assessment Risk communication
Basic approach to risk assessment
NRC – Red Book
Ecological and human health risk assessment
Ecological Risk Assessment Human Health Risk Assessment
Population, community and ecosystem • Predictive modeling of the threat posed by
levels exposure to hazards to human health
• Focuses on dose as it relates to the
• Ecotoxicology characteristics of the hazard
• Study of the ways in which polluting agents
disturb biological populations and communities
Dose (Ei) = CC x CR x EF
• Ecological Risk Assessment
BW
• Field surveys in terrestrial and aquatic
environments CC = constituent concentration in the medium of
• Fate and transport modeling concern (mg/L)
• Toxicity testing CR = contact rate with medium of concern (L/day)
• Bioaccumulation studies EF = exposure frequency with the medium of
• Risk characterization concern (days/year)
BW = body weight
Human health risk assessment
Inhalation
Ingestion
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