Version: 1.
Revision date: 09.12.2019
Safety Data Sheet
SECTION 1: Identification of the substance/mixture and of the company/undertaking
1.1 Product identifier
Trade name/designation: Acetone laboratory reagent
Product No.: A0140
Synonymes: 2-Propanone, Dimethyl ketone, DMK, Propanone
CAS No. 67-64-1
1.2 Relevant identified uses of the substance or mixture and uses advised against
Relevant identified uses: General chemical reagent
1.3 Details of the supplier of the safety data sheet
Supplier
Avantor Performance Materials India Ltd.
Street 501, 5th floor, Tiffany Building, Hiranandani Business Park,
Postal code/city Thane, Maharashtra - 400607, India
Telephone 022-41288100
Emergency phone number
Telephone 1800105561
Preparation Information
Product Information Compliance
1.4 E-mail SDS@[Link]
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SECTION 2: Hazard identification
2.1 Classification of the substance or mixture
Physical hazards
Flammable liquid, category 2
health hazards
Eye irritation, category 2
Specific target organ toxicity (single exposure),
category 3, narcotic effect
2.2 Label elements
Hazard pictograms
Signal word: Danger
Highly flammable liquid and vapour.
Causes serious eye irritation.
May cause drowsiness or dizziness.
2.3 Other hazards none
SECTION 3: Composition / information on ingredients
Substances
Substance name Acetone
Molecular formula CH₃COCH₃
Molecular weight 58.08 g/mol
CAS No. 67-64-1
SECTION 4: First aid measures
4.1 General information
IF exposed or if you feel unwell: Call a POISON CENTRE or doctor/physician. If unconscious place in
recovery position and seek medical advice. Never give anything by mouth to an unconscious person or a
person with cramps. Change contaminated, saturated clothing. Do not leave affected person unattended.
After inhalation
Call a POISON CENTRE/doctor. Remove casualty to fresh air and keep warm and at rest. If breathing is
irregular or stopped, administer artificial respiration.
In case of skin contact
After contact with skin, wash immediately with plenty of water and soap. Remove contaminated, saturated
clothing immediately. In case of skin reactions, consult a physician.
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After eye contact
In case of contact with eyes flush immediately with plenty of flowing water for 10 to 15 minutes holding
eyelids apart and consult an ophthalmologist. Protect uninjured eye. Remove contact lenses, if present and
easy to do. Continue rinsing.
In case of ingestion
If accidentally swallowed rinse the mouth with plenty of water (only if the person is conscious) and obtain
immediate medical attention. Do NOT induce vomiting. Give nothing to eat or drink.
4.2 Most important symptoms and effects, both acute and delayed
no data available
4.3 Indication of any immediate medical attention and special treatment needed
no data available
no data available
SECTION 5: Firefighting measures
5 1 Extinguishing media
Suitable extinguishing media
Water spray
ABC-powder
Carbon dioxide (CO2)
Nitrogen
Extinguishing media which must not be used for safety reasons
no restriction
5.2 Special hazards arising from the substance or mixture
In case of fire may be liberated:
Carbon monoxide
Carbon dioxide (CO2)
5.3 Advice for firefighters
DO NOT fight fire when fire reaches explosives.
Special protective equipment for firefighters
Wear a self-contained breathing apparatus and chemical protective clothing.
5.4 Additional information
Do not allow run-off from fire-fighting to enter drains or water courses.
Do not inhale explosion and combustion gases.
Use caution when applying carbon dioxide in confined spaces. Carbon dioxide can displace oxygen.
Use water spray jet to protect personnel and to cool endangered containers.
In case of fire: Evacuate area.
SECTION 6: Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
In case of major fire and large quantities: Remove persons to safety.
6.2 Environmental precautions
Discharge into the environment must be avoided.
6.3 Methods and material for containment and cleaning up
Spilled product must never be returned to the original container for recycling. Collect in closed and suitable
containers for disposal.
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6.4 Additional information
Clear spills immediately.
SECTION 7: Handling and storage
Precautions for safe handling
Avoid:
Inhalation
Avoid contact with eyes and skin.
Use extractor hood (laboratory).
If handled uncovered, arrangements with local exhaust ventilation have to be used.
If local exhaust ventilation is not possible or not sufficient, the entire working area must be ventilated by
technical means.
Keep away from sources of ignition - No smoking.
Usual measures for fire prevention.
Take precautionary measures against static discharges.
Conditions for safe storage, including any incompatibilities
Recommended storage temperature: Keep bottles tightly closed and away from sources of ignition and
heat.
Keep container tightly closed and in a well-ventilated place. Keep/Store away from combustible materials.
Specific end use(s)
no data available
SECTION 8: Exposure controls/personal protection
8.1 Control parameters
Does not contain substances above concentration limits fixing an occupational exposure limit.
8.2 Exposure controls
Appropriate engineering controls
no data available
Personal protection equipment
no data available
Eye/face protection
no data available
Skin protection
When handling with chemical substances, protective gloves must be worn with the CE-label including the
four control digits. Recommended glove articles DIN-/EN-Norms: EN ISO 374 In the case of wanting to use
the gloves again, clean them before taking off and air them well.
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By short-term hand contact
Suitable material: CR (polychloroprene, chloroprene rubber)
Thickness of the glove material: 0,75 mm
Breakthrough time (maximum wearing < 30 min
time):
By long-term hand contact
Suitable material: Butyl caoutchouc (butyl rubber)
Thickness of the glove material: 0,50 mm
Breakthrough time (maximum wearing > 480 min
time):
Respiratory protection
no data available
Additional information
no data available
Environmental exposure controls
no data available
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SECTION 9: Physical and chemical properties
9.1 Information on basic physical and chemical properties
(a) Appearance
Physical state: liquid
Colour: colourless
(b) Odour: characteristic
(c) Odour threshold: no data available
Safety relevant basic data
(d) pH: 5-6 (400 g/l; H2O; 20 °C)
(e) Melting point/freezing point: -95.4 °C
(f) Initial boiling point and boiling range: 56.2 °C (1013 hPa)
(g) Flash point: < -20 °C (closed cup)
(h) Evaporation rate: no data available
(i) Flammability (solid, gas): Highly flammable liquid and vapour.
(j) Flammability or explosive limits
Lower explosion limit: 2.6 % (v/v)
Upper explosion limit: 12.8 % (v/v)
(k) Vapour pressure: 233 hPa (20 °C)
(l) Vapour density: 2.01 (20 °C)
(m) Relative density: 0.792 g/cm³ (20 °C)
(n) Solubility(ies)
Water solubility (g/L): soluble (20 °C)
Soluble (g/L) in Ethanol: no data available
(o) Partition coefficient: n-octanol/water: -0.24 (20 °C)
(p) Auto-ignition temperature: 465 °C (DIN 51794)
(q) Decomposition temperature: no data available
(r) Viscosity
Kinematic viscosity: no data available
Dynamic viscosity: 0.32 mPa*s (20 °C)
(s) Explosive properties: not applicable
(t) Oxidising properties: not applicable
9.2 Other information
Bulk density: no data available
Refraction index: 1.3591 (589 nm; 20 °C)
Dissociation constant: no data available
Surface tension: no data available
Henry's Law Constant: no data available
SECTION 10: Stability and reactivity
10.1 Reactivity
Vapours are heavier than air, spread along floors and form explosive mixtures with air.
10.2 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature).
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10.3 Possibility of hazardous reactions
Formation of explosive mixtures with:
Oxidising agent, strong
Reducing agent, strong
Nitric acid
Trichloromethane
Peroxides
Violent reaction with:
Alkali (lye)
Oxidising agent
Reducing agent
Exothermic reaction with:
Bromine
Chlorine
10.4 Conditions to avoid
UV-radiation/sunlight
Heat
This material is combustible and can be ignited by heat, sparks, flames, or other sources of ignition (e.g.
static electricity, pilot lights, or mechanical/electrical equipment).
10.5 Incompatible materials
Rubber articles
Plastic articles
10.6 Hazardous decomposition products
no data available
SECTION 11: Toxicological information
11.1 Information on toxicological effects
Acute effects
Acute oral toxicity:
LD50: > 5800 mg/kg - Rat - (RTECS)
Acute dermal toxicity:
LD50: > 20000 mg/kg - Rabbit - (IUCLID)
Acute inhalation toxicity:
LC50: > 76 mg/l (4h) - Rat
Irritant and corrosive effects
Primary irritation to the skin:
not applicable
Irritation to eyes:
Causes serious eye irritation.
Irritation to respiratory tract:
not applicable
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Respiratory or skin sensitisation
In case of skin contact: not sensitising
After inhalation: not sensitising
STOT-single exposure
May cause drowsiness or dizziness.
STOT-repeated exposure
not applicable
CMR effects (carcinogenicity, mutagenicity and toxicity for reproduction)
Carcinogenicity
Germ cell mutagenicity
No indications of human germ cell mutagenicity exist.
Reproductive toxicity
No indications of human reproductive toxicity exist.
Aspiration hazard
not applicable
Other adverse effects
no data available
SECTION 12: Ecological information
12.1 Ecotoxicity
Fish toxicity:
LC50: 8300 mg/l (96 h) - Cairns, [Link]., and A. Scheier 1968. A Comparison of the Toxicity of Some
Common Industrial Waste Components Tested Individually and Combined. [Link]-Cult. 30(1):3-8
Daphnia toxicity:
EC50: 18500 mg/l (48 h) - Randall, T.L., and P.V. Knopp 1980. Detoxification of Specific Organic
Substances by Wet Oxidation. [Link] [Link] Fed. 52(8):2117-2130
LC50: 8450 mg/l (48 h) - Cowgill, U.M., and D.P. Milazzo 1991. The Sensitivity of Ceriodaphnia dubia and
Daphnia magna to Seven Chemicals Utilizing the Three-Brood Test. [Link].
20(2):211-217
Algae toxicity:
EC50: 7200 mg/l (96 h) - Slooff, W. 1982. A Comparative Study on the Short-Term Effects of 15
Chemicals on Fresh Water Organisms of Different Tropic Levels. [Link]., Springfield, VA :25
p. (DUT) (ENG ABS) (NTIS/PB83-200386)
Bacteria toxicity:
no data available
12.2 Persistence and degradability
no data available
12.3 Bioaccumulative potential
Partition coefficient: n-octanol/water: -0.24 (20 °C)
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12.4 Mobility in soil:
no data available
12.5 Results of PBT/vPvB assessment
no data available
12.6 Other adverse effects
no data available
SECTION 13: Disposal considerations
13.1 Waste treatment methods
Appropriate disposal / Product
Dispose according to local legislation. Consult the appropriate local waste disposal expert about waste
disposal.
Appropriate disposal / Package
Dispose according to local legislation. Handle contaminated packages in the same way as the substance
itself.
SECTION 14: Transport information
Land transport (ADR/RID)
14.1 UN-No.: 1090
14.2 Proper Shipping Name: ACETONE
14.3 Class(es): 3
Classification code: F1
Hazard label(s): 3
14.4 Packing group: II
14.5 Environmental hazards: No
14.6 Special precautions for user:
Hazard identification number (Kemler 33
No.):
tunnel restriction code: D/E
(Passage forbidden through tunnels of category D when
carried in bulk or in tanks. Passage forbidden through
tunnels of category E.)
Sea transport (IMDG)
14.1 UN-No.: 1090
14.2 Proper Shipping Name: ACETONE
14.3 Class(es): 3
Classification code:
Hazard label(s): 3
14.4 Packing group: II
14.5 Environmental hazards: No
Marine pollutant: No
14.6 Special precautions for user:
Segregation group: -
EmS-No. F-E S-D
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
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not relevant
Air transport (ICAO-TI / IATA-DGR)
14.1 UN-No.: 1090
14.2 Proper Shipping Name: ACETONE
14.3 Class(es): 3
Classification code:
Hazard label(s): 3
14.4 Packing group: II
14.5 Special precautions for user:
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SECTION 15: Regulatory information
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
SECTION 16: Other information
Abbreviations and acronyms
ACGIH - American Conference of Governmental Industrial Hygiensts
ADR - European Agreement concerning the International Carriage of Dangerous Goods by Road
AGS - Committee on Hazardous Substances (Ausschuss für Gefahrstoffe)
CLP - Regulation on Classification, Labelling and Packaging of Substances and Mixtures
DFG - German Research Foundation (Deutsche Forschungsgemeinschaft)
Gestis - Information system on hazardous substances of the German Social Accident Insurance
(Gefahrstoffinformationssystem der Deutschen Gesetzlichen Unfallversicherung)
IATA-DGR - International Air Transport Association-Dangerous Goods Regulations
ICAO-TI - International Civil Aviation Organization-Technical Instructions
IMDG - International Maritime Code for Dangerous Goods
LTV - Long Term Value
NIOSH - National Institute for Occupational Safety and Health
OSHA - Occupational Safety & Health Administration
PBT - Persistent, Bioaccumulative and Toxic
RID - Regulation concerning the International Carriage of Dangerous Goods by Rail
STV - Short Term Value
SVHC - Substances of Very High Concern
vPvB - very Persistent, very Bioaccumulative
Additional information
Indication of changes: none
Disclaimer
The information provided in this Safety Data Sheet (SDS) was prepared based on data believed to be accurate
as of the date of this SDS. TO THE GREATEST EXTENT PERMITTED BY LAW, AVANTOR PERFORMANCE
MATERIALS (“AVANTOR”) EXPRESSLY DISCLAIMS ANY AND ALL REPRESENTATIONS AND
WARRANTIES REGARDING THE INFORMATION CONTAINED HEREIN INCLUDING, WITHOUT
LIMITATION, AS TO ACCURACY, COMPLETENESS, FITNESS FOR PURPOSE OR USE,
MERCHANTABILITY, NON-INFRINGEMENT, PERFORMANCE, SAFETY, SUITABILITY AND STABILITY. This
SDS is intended as a guide to the appropriate use, handling, storage and disposal of the product to which it
relates by properly trained personnel, and is not intended to be comprehensive. Users of Avantor’s products are
advised to perform their own tests and to exercise their own judgment to determine the safety, suitability and
appropriate use, handling, storage and disposal of each product and product combination for their own
purposes and uses. TO THE GREATEST EXTENT PERMITTED BY LAW, AVANTOR DISCLAIMS LIABILITY
FOR, AND BY USING AVANTOR’S PRODUCTS THE PURCHASER AGREES THAT UNDER NO
CIRCUMSTANCES SHALL AVANTOR BE LIABLE FOR, SPECIAL, INDIRECT, INCIDENTAL, PUNITIVE OR
CONSEQUENTIAL DAMAGE OF ANY TYPE OR KIND, INCLUDING WITHOUT LIMITATION, FOR LOSS OF
PROFITS, REPUTATIONAL DAMAGE, PRODUCT RECALL OR BUSINESS INTERRUPTION.
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