MCQs and Cases : Female Pathology

Made by : Mohammed Alamami

1. Which of the following is not true about Duct Ectasia :
a. It starts with narrowing of the ducts then they dilate
b. It’s either associated with Granulomatous or Plasma cell mastitis
c. It ends with fibrosis and narrowing of the ducts
d. Both B + C
2. Which of the following is a (non proliferative epithelial lesion)
a. Ductal atypical hyperplasia
b. Complex sclerosing lesion
c. Fibrocystic Changes
d. Florid hyperplasia
3. Which of the following has the highest risk of developing into cancer :
a. Ductal typical hyperplasia
b. Florid hyperplasia
c. Ductal Atypical hyperplasia
d. Fibrocystic changes
4. What is the most common tumor of the Breast :
a. Phyllodes tumor
b. Fibroadenoma
c. Ductal Papilloma
d. None of the above
5. Which of the following is not a modifiable risk factor of Breast cancer :
a. Diet
b. Exogenous Estrogen
c. Family history
d. Smoking
6. Which of the following in a non-invasive
cinoma
carof breast
a. Mucinous carcinoma
 b. Tubular Carcinoma
c. Ductal Carcinoma
d. Ductal carcinoma in situ
7. What is the most common invasive type of Breast cancer ?
a. Mucinous
b. Inflammatory
c. Ductal
d. Lobular
8. A 40 years old female was admitted to the clinic, suffering from ((many cha
in the skin of and a mass)) in her right breast, a biopsy was taken, and
undermicroscpose it shows a lot of malignant epithelial cells infiltrating and
obstructing lymphatic vessels of the breast, in this case, and according to th
new gross morphological changes in the breast, we can refer to this cancer
A. Inflammatory carcinoma
B. Ductal Carcinoma
C. INTRA Lobular carcinoma
D. None of the above
9. A 37 years old female presents to the clinic suffering from (Eczema Like les
on the skin of her right nipple, After taking history, She says that she has a
family history of breast cancer, and she was taking OCPs regularly in the pa
few years of her life, but after taking a biopsy from her breast it shows
(Dysplastic cells above the basement membrane only), according to all of th
info, what is the best diagnosis for here (Eczema Like lesions) :
A. Fibro-adenoma of Breast
B. Gynicomastia
C. Ductal carcinoma in situ
D. Paget Disease of the breast
10.A 45 years old female presents to the clinic suffering from a mass in her rig
Breast, A biopsy was taken and examined under microscope, and it confirm
that it is a malignant cancer, other Examinations were performed and they
 confirmed that the malignant cells have Neither Estrogen nor Progesterone
Receptors, which one of the following types of breast cancer this female mo
has :
A. Medullary carcinoma
B. Mucinous Carcioma
C. Intralobular carcinoma
D. Ductal carcinoma
[Link] one of the following micro-organisms can mostly cause female
infertility ?
a. Candida albicans
b. HSV
c. HPV
d. Neisseria Gonorrhoea
[Link] of the following is not true about PID caused by Gonorrhoea :
A. It can cause Pyo-salpinxs
B. It can lead to female infertility
C. It can cause hydro-salpinx
D. Bacteria Usually spread upward through lymphatic's and blood vessels
[Link] of the following is true about Puerperal infections :
a. They are sexually transmitted
b. have the higher risk for bacteremia
c. They spread superfiscially on the mucosa
d. The are caused by only one single micro-organism
[Link] of the following is caused by an infection/inflammation :
A. Labial hypertrophy
B. Labial hypoplasia
C. Ectopic mammary tissue of vulva
D. Bartholin Cyst
[Link] is a microscopic finding that is characteristic for :
A. HSV-1
 B. HSV-2
C. Troponema Pallidum
D. HPV 11,6
[Link] is the name of the lesion found in the 2ry stage of syphilis :
A. Condyoloma Accuminatus
B. Condyloma Latum
C. Chancre
D. None of the above
[Link] of the following is wrong about Lichen Sclerosus ?
A. It's associated with Dermal Fibrosis
B. It's associated with Atrohy of the Epidermis
C. It has 4-5% risk to develop into SCC
D. It's associated with Chronic inflammatory cells in dermis
[Link] of the following are causes of Vulvar Leukoplakia, Except :
A. Vulvar Dystrophies
B. Syphilis
C. Vitiligo
D. Cancer of Vulva
[Link] Cancer of Vulva, all of the following are true, Except :
a. Bowen's Disease is stage 3 intra-epithelial Carcinoma (Squamous cell
carcinoma is Situ)
b. SCC in vulva is mostly associated with HPV infection
c. Paget Disease of Vulva is usually associated with Invasive Carcinoma
d. SCC that is not caused by HPV, usually occurs in Old females
th
20.A 28 years old female was treated with intra-uterine DESB during her 6
month of pregnancy, her daughter will be at high risk of developing :
A. Vaginal Rhabdomyosarcoma
B. Vaginal Adenosis
C. Clear Cell adenocarcinoma
D. Both B + C
[Link] Cysts are found in :
a. Vulva
b. Ovaries
c. Cervix
d. Breast
[Link] of the following are high risk factors of Cervicitis, except :
A. Rough intercourse
B. Infections
C. After labor
D. Acidity of Cervical secretions
[Link] of the following are true about cervical polyps except :
A. They can easily change into a malignant cancer
B. They are usually single
C. The can cause hemorrhage
D. Non of the above
[Link] of the following is not a risk factor for developing malignant cervcica
carcinoma :
A. Smoking
B. Family history
C. OCPs
D. HPV 6,11
[Link] of the following is true about cervical cancer :
A. When it surrounds half of the cervix, it's called: Barrel Cervix
B. The most common microscopic type of it is : Squamous cell carcinoma
C. It's not associated with Vaginal Bleeding and Dysuria
D. HPV vaccinations are not useful in protection
[Link] is the Characteristic cell for Chronic Endometritis ?
A. Neutrophil
B. Lymphocytes
C. Plasma Cell
 D. None of the above
[Link] an autopsy of a females body, it was found that she had an ectopic
endometriotic tissue located outside the uterus, this condition is called :
A. Endometritis
B. Endometrial Hyperplasia
C. Adenomyosis
D. Endometriosis
[Link] are the most common organs affected with Endometriosis :
A. Spleen
B. Liver
C. Uterus
D. Ovaries
[Link] of the following is High Risk factor for Endometritis :
A. OCPs
B. Acidity of Cervical secretions
C. Intra-uterine contraceptive Devices
D. Non of the above
[Link] of the following is helpful in the treatment of Endometriosis except :
A. COX-2 inhibitors
B. DNA polymerase inhibitors
C. Aromatase inhibitor's
D. Both A + C
[Link] of the following conditions can not lead to Infertility :
A. Endometriosis
B. Adenomyosis
C. Gonorrhea
D. Cervicitis
[Link] of the following are causes of organic bleeding except :
A. Leiomyoma
B. Endometrial Hyperplasia
 C. An ovulatory cycle
D. Endometrial Hyperplasia
[Link] of the following conditions are high risk for developing Endometrial Canc
except :
a. Polycystic Ovarian Syndrome
b. Hormone replacement therapy
c. Estrogen producing adrenal Tumor
d. Endometrial Polyp
34.A 32 years old female, presented to the clinic suffering from irregular vagin
bleeding, laboratory tests and examinations were performed, and they
confirmed the presence of multiple circumscribed masses in the wall of her
Uterus, the Patient History indicated that she was taking OCPs regularly in t
past few years, What is the most appropriate diagnosis for these masses ?
A. Fibro adenoma
B. Leiomyoma
C. Endometrial Polyps
D. Endometrial Carcinoma
35.A 70 years old female was admitted to the hospital suffering from irregular
vaginal bleeding, CT scan and Other examination were performed, and the
examinations confirmed the presence of fluid filled malignant masses in So
parts of here endometrium, What is the most appropriate Diagnosis ?
A. Leiomyoma
B. Leiomyosarcoma
C. Endometrioid Endometrial Carcinoma
D. Serous Endometrial Carcinoma
[Link] is the most common site for Ectopic Pregnancy ?
A. Stomach
B. Vagina
C. Fallopian tubes
D. None of the abov
[Link] of the following are possible complication of Ectopic pregnancy except :
A. Hematosaplinx
B. Hypovolemic shock
C. Rupture of Fallopian tube
D. Fallopian tube cancer
[Link] of the following can lead to the development of ectopic pregnancy excep
A. Leiomyoma
B. Intra-uterine contraceptive devices
C. PID
D. Endometriosis
[Link] of the following are true regarding Ascending Placental infection, except
a. They spread to the placenta through the blood
b. They can be caused by Vaginal flora
c. They are the most common type of placental infections
d. They can lead to Acute chorio-Amnionitis
40.A pregnant female at her7th month of pregnancy, suddenly develops HTN,
with no other symptoms, which of the following is the best Diagnosis :
A. Pheochromocytoma
B. Chronic HTN
C. Gestational HTN
D. Pre-Eclampasia
[Link] of the following is true About Pre-Eclampasia :
A. The presence of HTN with no Proteinuria
B. The main Event is thought to be Placental Ischemia
C. Spiral arteries are well remodeled in this disease
D. All of the above is true
[Link] of the following is not a morphological change of the placenta in Pre-
Eclampsia :
A. Infarction
B. Liquefactive Necrosis
 C. Acute Atherosis
D. Retro-placental Hematoma
[Link] of the following are Molar Lesions excepts :
A. Complete Mole
B. Partial Mole
C. invasive Mole
D. Choriocarcinoma
[Link] of the following produces the Highest amount of HCG :
a. Complete Mole
b. Partial Mole
c. Invasive Mole
d. Choriocarcinoma
[Link] of the following has the ability to metastasis ?
A. Complete Mole
B. Partial Mole
C. Invasive Mole
D. None of the above
[Link] of the following is wrong about complete Mole :
A. The placenta is totally affected
B. There is a diffuse proliferation of trophoblastic cells
C. High risk of developing toxemia of pregnancy
D. Results from the fertilization of a normal ovum
[Link] of the following is true about Partial Mole
A. All of the placenta is Affected
B. It almost has no risk of developing choriocarcinoma
C. High risk of developing Pre-eclampsia
D. Fetal Part are not found
[Link] of the following is true regarding trophoblastic diseases :
A. Choriocarcinoma is classified as a molar lesion
B. Partial Mole shows no fetal parts
 C. Complete Mole has no risk of developing Choriocarcinoma
D. Complete Mole results from the fertilization of an empty ovum
[Link] of the following is wrong about choriocarcinoma :
A. Under microscope it shows no Villi
B. Gestational type is chemo sensitive
C. Non-Gestational type develops in the gonads
D. It spread early by Lymphatics
[Link] of the following is not found in Polycystic Ovarian syndrome :
A. Low estrogen Levels
B. Diabetes Like Symptoms
C. Obesity
D. High Male Androgen Levels
51.A 30 year-old woman has an infertility workup. Her BMI is 32. Hirsuitims is
noted. On pelvic examination, bilateral adnexal masses are palpated. Trans
vaginal ultrasound examination shows a normal sized uterus, but the ovarie
enlarged and have a dozen peripheral follicles. Laboratory studies show
hyperglycemia and increased androgenic steroids. For which of the followin
conditions is she at greatest risk?
A. Malignant mixed mullerian tumor
B. Endometrial hyperplasia
C. Adenomyosis
D. Vulvar Squamous cell Papilloma
52.A 25-year-old woman in her fifteenth week of pregnancy presents with uteri
bleeding and passage of a small amount of watery fluid and tissue. Her uter
found to be filled with cystic, avascular, grapelike structures that do not
penetrate the uterine wall. No fetal parts are found. The most likely diagnos
for this abnormality is:
a. Choriocarcinoma
b. Complete hydatidiform mole
c. Invasive mole.
 d. Partial hydatidiform mole
53.47-year-old woman has noted a pressure sensation, but no pain, in her pelv
region for the past 5 months. On physical examination there is a right adne
fine needle aspirate of the mass is performed and cytologic examination of
fluid aspirated from the mass reveals clusters of malignant epithelial cells m
An ultrasound scan shows a 10 cm fluid-filled cystic mass in the right ovary.
surrounding psammoma bodies. Which of the following neoplasms is she m
likely to have?
a) Endometrioid carcinoma.
b) Malignant mesothelioma.
c) Mature cystic teratoma.
d) Serous cystadenocarcinoma.
[Link] of the following is not A risk factor for developing Ovarian cancer :
A. P53 mutation
B. Nulliparity
C. Family history
D. Ligation of the fallopian tubes
[Link] of the following is not a Germ cell tumor :
A. Dysgerminoma
B. Tetatoma
C. Brunner Tumor
D. Choriocarcinoma
[Link] of the following is a metastatic Ovarian tumor :
A. Brunner tumor
B. Thecoma
C. Yolk sac tumor
D. Krukenberg tumor
[Link] one of the following classes of ovarian tumors is the most common ?
A. Surface epithelium tumors
B. Germ cell tumors
 C. Sex cord tumors
D. Metastatic tumors
[Link] of the following tumors can lead to (pseudomyxoma Peritonei) :
A. Serous epithelial tumors
B. Mucinous Epithelial tumors
C. Brunner Tumors
D. None of the above
[Link] of the following Tumors of the ovary have the highest risk of
developing endometrial cancer :
A. Krukenberg tumor
B. Brunner Tumor
C. Endometrial epithelial cancer
D. Dysgerminoma
60.A 42 years old female presents to the clinic suffering from An abdominal pa
with Difficulty in Breathing, CT scan were taken and examination show that
she has fluid accumulation both in here thoracic and Abdominal cavitites, w
A mass developing in here left ovary, which of the following is the best
diagnosis for this case :
A. Serous Epithelial tumor
B. Mucinous Epithelial tumor
C. Theco-Fibroma
D. Krukenberg tumor
 MCQs for : Pathology of Male reproduc
Organs
Made by : Mohammed Alamami
1- Which of the following is true about Congenital anomalies of the
A. Hypospadias is a condition in which urethra opens on the vent
of penis
B. Epispadius is condition in which urethra fails to open on any s
the penis
C. Phimosis is a condition in which the orifice of the prepuce is e
wide and protruding
D. All of the above are true
2- Which of the following is wrong about Gonorrhoea in Males :
A. At first it starts as acute suppurative inflammation of the ante
B. It can spread upward to casue Prostitis and Cystitis
C. It's more common in circumcised Males
D. Bacteremia may cause Arthritis and Endocarditis
3- Which of the following is wrong about Penile Papilloma :
A. It's originated from stratified squamous epithelium
B. It's a Benign mass
C. It's usually causes by an infection of HPV 16 ot 18
D. The cell show peri-nuclear halo under microscope, a character
as : "Koiliocytosis"
4- Which of the following is true about Penile squamous carcinoma
A. Bowen diseases is unique to Penis only
B. Bowen diseases is Asccoiated with Visceral Malignancies
 C. Bowenoid Papulosis usually can transform into invasive squam
carcinoma
D. Erythroplasia of Querat appears as Dark Black ulcers
5- Which of the following is true about Penile Squamous Cell Carcin
A. It's more common in Females
B. It's usually preceded by and infection of HPV 16,18,31, or 33
C. It's more common in Muslims
D. Usually it affected young ages
6- Which of the following is wrong about congenital anomalies of T
A. An-orchism is the failure of Embryonic formation of testicles
B. Syn-orchism is the fusion of testicles
C. Crypto-orchidism is the ascending of testicles into thoracic ca
D. All of the above are wrong
7- All of the following are causes for Crypto-orchidism except :
A. Narrow inguinal ring
B. Short Spermatic cord
C. Adhesion
D. Trisomy 21
8- All of the following can be found in a child diagnosed with Undes
testicles, except :
A. Testicular Cancer
B. Hernia
C. Polyuria
D. Azospermia
9- What is the most common cause of Male infertility :
A- High estrogen
B- Varicocele
 C- Obstruction of spermatic cord
D- Crypto-orchidism
10- Which of the following is true about testicular torsion ?
A- It will lead to severe suppurative inflammation of Testicles
B- It will lead to hemorrhagic infarction of testicles
C- In this case all of the components of spermatic cord are com
D- Both B + C are true
11- Which of following is wrong regarding fluid accumulations in
testicles :
A. Hematocele occurs usually due to trauma
B. Varicocle is due to abnormality in the testicular artery
C. Hydrocele may occur in a patient with Generalized Edema
D. Spermatocele is sperm contiang cyst inside testicles
12- Which of the following is not a risk factor for Testicular canc
A. Isochromosome of short arm of chromosome 12
B. Intra-tubular germ cell neoplasia
C. An-orchism
D. Kline-felter Syndrome
13- What is the most common class of testicular tumors ?
A- Germ cell tumors
B- Lymphomas
C- Sex-cord tumors
D- Metastatic tumors
14- All of the following are tumor markers used for diagnosis of
Testicular tumors, except :
A- HCG
B- AFP
 C- CEA
D- Parathyroid hormone
15- Regarding seminoma, which of the following is true :
A- Anaplastic seminoma has the best prognosis
B- Classis seminoma show inflammatory cell infiltration, with Go
prognosis
C- Classis and Spermatocytic seminoma usually show metasta
organs
D- Anaplastic seminoma never shows metastasis
16- Which of the following is characterized for Endodermal sinu
A- High Testosterone Synthesis
B- It's A benign tumor
C- It's A metastatic tumor
D- Show cuboidal cell arrangement around blood vessels (Schi
Bodies)
17- Which of the following is wrong about testicular choriocarcin
A- It's one of the germ cell tumor
B- It usually occurs as a pure choriocarcinoma
C- It produces large amounts of HCG
D- All of the above is true
18- Which of the following is A benign tumor :
A- Embryonal Carcinoma
B- Testicular Lymphoma
C- Choriocarcinoma
D- Androblastoma
19- What is the most common tumor cancer in Old Males ?
A- Non Hodgkin Large B cell lymphoma
 B- Seminoma
C- Choriocarcinoma
D- Endodermal Sinus Tumor
20- Which of the following is the most common testicular tumor
children ?
A- Endodermal sinus tumor
B- Teratoma
C- Seminoma
D- Choriocarcinoma
21- Which of the following is wrong regarding Benign Prostatic
Hyperplasia :
A- It's most common in Old ages (after 80 yrs)
B- It leads to dilation of Urethra
C- It's usually due to an Endocrine imbalance
D- It shows hyperplasia of either the Glandular or the Stromal
Prostate
22- Which of the following is wrong regarding Prostatic Carcinom
A- It usually arises in the Posterior Part of the Gland
B- It can be examined by Rectal Examination
C- Undifferentiated carcinoma shows plasma elevation of PSA
D- It the most common cancer in MEN
23- Which of the following is true regarding Prostatic carcinoma
A- Occult carcinoma is discovered During Autopsy
B- It's microscopic type is usually squamous cell carcinoma
C- Rectal invasion is Rare due to the presence of DenoVillers F
D- It can spread by Lymphatics to the Bones
24- Which of the following would not be a risk factor for Prostat
Carcinoma :
A- High Testosterone Level
B- Family History
C- High Estrogen Level
D- All of the above are not risk factors for Prosatic Carcinoma