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PHRM4010 Exam: Medicine Dosage Formulas

This document provides formulas for calculating creatinine clearance, ideal body weight, body mass index, and dosing adjustments for medications in renal impairment. It includes the Cockcroft-Gault formula for calculating creatinine clearance based on age, weight, and serum creatinine. It also provides formulas for calculating ideal body weight based on height and adjusting medication dosages based on creatinine clearance and the medication's fraction excreted unchanged in urine.

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Hyun Jun Yang
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5 views1 page

PHRM4010 Exam: Medicine Dosage Formulas

This document provides formulas for calculating creatinine clearance, ideal body weight, body mass index, and dosing adjustments for medications in renal impairment. It includes the Cockcroft-Gault formula for calculating creatinine clearance based on age, weight, and serum creatinine. It also provides formulas for calculating ideal body weight based on height and adjusting medication dosages based on creatinine clearance and the medication's fraction excreted unchanged in urine.

Uploaded by

Hyun Jun Yang
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd

PHRM4010: Quality Use of Medicines C Sample Examination

PHRM 4010 FORMULAE FOR SEMESTER ONE EXAM CrCL (ml/min) = (140-age[yr])*WT[kg]/(0.814*serum creatinine [micromol/L])*0.85[female] CrCL (ml/min) = (140-age[yr])*WT[kg]/(0.814*serum creatinine [micromol/L]) IBW (kg) = (HT[cm]-150)*0.9 + 50 (male) IBW (kg) = (HT[cm]-150)*0.9 + 45 (female) BMI (kg/m2) = WT[kg]/HT[m]2 HT = height, WT = weight Dosing in renal ImpairmentIf fu > 90% Dose (renal failure) / Dose (normal) = CrCL (renal failure) / CrCL (normal) If fe=50 to 90% Dose (renal failure) / Dose (normal) = (1-fe) + (CrCL [renal failure] / CrCL [normal]) * fe For calculations assume normal renal function is 100 mL/min

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