Overview of Protein Synthesis Process
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Dr. M. Prasad NaiduOverview of Protein Synthesis Process
Uploaded by
Dr. M. Prasad NaiduProtein Synthesis
[Link] Naidu
MSc Medical Biochemistry, Ph.D,.
A U G G G C U U A A A G C A G U G C A C G U U
This is a molecule of messenger RNA.
It was made in the nucleus by
transcription from a DNA molecule.
mRNA molecule
codon
A U G G G C U U A A A G C A G U G C A C G U U
A ribosome on the rough endoplasmic
reticulum attaches to the mRNA
molecule.
ribosome
A U G G G C U U A A A G C A G U G C A C G U U
It brings an amino acid to the first three
bases (codon) on the mRNA.
Amino acid
tRNA molecule
anticodon
U A C
A transfer RNA molecule arrives.
The three unpaired bases (anticodon)
on the tRNA link up with the codon.
A U G G G C U U A A A G C A G U G C A C G U U
Another tRNA molecule comes into
place, bringing a second amino acid.
U A C
Its anticodon links up with the second
codon on the mRNA.
A U G G G C U U A A A G C A G U G C A C G U U
A peptide bond forms between the
two amino acids.
Peptide bond
A U G G G C U U A A A G C A G U G C A C G U U
The first tRNA molecule releases its amino
acid and moves off into the cytoplasm.
A U G G G C U U A A A G C A G U G C A C G U U
The ribosome moves along the mRNA to
the next codon.
A U G G G C U U A A A G C A G U G C A C G U U
Another tRNA molecule brings
the next amino acid into place.
A U G G G C U U A A A G C A G U G C A C G U U
A peptide bond joins the second
and third amino acids to form a
polypeptide chain.
A U G G G C U U A A A G C A G U G C A C G U U
The polypeptide chain gets longer.
The process continues.
This continues until a termination
(stop) codon is reached.
The polypeptide is then complete.
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